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PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 12, p. e16000
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2007, Volume 282, Issue 27, pp. 19762 - 19772
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 12/2015, Volume 36, Issue 6, pp. 1451 - 1463
The CCN family of proteins comprises the members CCN1, CCN2, CCN3, CCN4, CCN5 and CCN6. They share four evolutionarily conserved functional domains, and... 
cancers | receptors | signalling pathways | cell functions | CCN family proteins | TISSUE-GROWTH-FACTOR | PROGRESSIVE PSEUDORHEUMATOID DYSPLASIA | MEDICINE, RESEARCH & EXPERIMENTAL | IMMEDIATE-EARLY GENE | DIFFERENTIAL EXPRESSION | FACTOR-BINDING PROTEIN | K-1735 MURINE MELANOMA | SIGNALING PATHWAY | FACTOR CTGF | HEPARAN-SULFATE PROTEOGLYCANS | INFLAMMATORY BREAST-CANCER | Neoplasms - metabolism | Proto-Oncogene Proteins - metabolism | CCN Intercellular Signaling Proteins - genetics | Cysteine-Rich Protein 61 - genetics | Humans | Carcinogenesis - genetics | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Carcinogenesis - metabolism | Cysteine-Rich Protein 61 - metabolism | Nephroblastoma Overexpressed Protein - metabolism | Neoplasm Metastasis | Nephroblastoma Overexpressed Protein - genetics | Neoplasms - genetics | CCN Intercellular Signaling Proteins - metabolism | Connective Tissue Growth Factor - genetics | Neoplasms - pathology | Connective Tissue Growth Factor - metabolism | Repressor Proteins - metabolism | Genetic aspects | Cellular signal transduction | Metastasis | Carcinogenesis | Health aspects | Motility | Colorectal cancer | Amino acids | Insulin-like growth factors | Breast cancer | Kinases | Insulin | Ovarian cancer | Cell adhesion & migration | Proteins | Angiogenesis | Ligands | Tumorigenesis | Localization | Vascular endothelial growth factor | Prostate cancer | Tumors
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 12/2017, Volume 74, Issue 23, pp. 4269 - 4277
Periostin is a matricellular protein that is composed of a multi-domain structure with an amino-terminal EMI domain, a tandem repeat of four FAS 1 domains, and... 
Life Sciences | Biomedicine, general | Biochemistry, general | EMI | FAS 1 | Tenascin | Life Sciences, general | Collagen | Fibronectin | Cell Biology | BMP-1 | LYSYL OXIDASE | CORNEAL DYSTROPHIES | CANCER-ASSOCIATED FIBROBLASTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERIODONTAL-LIGAMENT | AGENT TARGETING PERIOSTIN | EPITHELIAL OVARIAN-CARCINOMA | CELL BIOLOGY | GROWTH-FACTOR-BETA | MATRICELLULAR PROTEIN | COLLAGEN FIBRILLOGENESIS | ACUTE MYOCARDIAL-INFARCTION | Cell Adhesion Molecules - genetics | Tenascin - genetics | Humans | Tenascin - metabolism | Bone Morphogenetic Protein 1 - genetics | Nephroblastoma Overexpressed Protein - genetics | Protein Isoforms - metabolism | Connective Tissue - anatomy & histology | Collagen - genetics | Protein Interaction Domains and Motifs | Bone Morphogenetic Protein 1 - metabolism | Gene Expression | Signal Transduction | Proteoglycans - metabolism | Cell Adhesion Molecules - metabolism | Connective Tissue - metabolism | Fibronectins - metabolism | Nephroblastoma Overexpressed Protein - metabolism | Protein Interaction Mapping | Laminin - genetics | Collagen - metabolism | Protein Binding | Fibronectins - genetics | Laminin - metabolism | Protein Isoforms - genetics | Oxidases | Fibronectins | Crosslinked polymers | Laminin | Architecture | Protein binding | Construction | Collagen (type I) | Homeostasis | Crosslinking | Amino acids | Tissues | Lysyl oxidase | Connective tissues | Proteins | Electromagnetic interference | Extracellular matrix | Bone morphogenetic proteins | Assembly | Binding sites
Journal Article
Matrix Biology, ISSN 0945-053X, 05/2017, Volume 59, pp. 23 - 38
Members of the CCN family of matricellular proteins are cytokines linking cells to the extracellular matrix. We report that CCN3 (Nov) and CCN5 (WISP2) are... 
MMP | Degradomics | Proteolysis | Yeast two-hybrid | Substrate trap | Inactive catalytic domain capture | CCN | ICAT | TISSUE-GROWTH-FACTOR | HEPARIN-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | POSSIBLE MECHANISM | CELL BIOLOGY | BREAST-CANCER CELLS | GELATINASE-A | FACTOR CTGF | BIOLOGICAL-ACTIVITY | EXTRACELLULAR-MATRIX | UP-REGULATION | PROTEASE DEGRADOMICS | CCN Intercellular Signaling Proteins - genetics | Saccharomyces cerevisiae - genetics | Humans | Substrate Specificity | Saccharomyces cerevisiae - metabolism | Nephroblastoma Overexpressed Protein - chemistry | Nephroblastoma Overexpressed Protein - genetics | MCF-7 Cells | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Binding Sites | CCN Intercellular Signaling Proteins - chemistry | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Repressor Proteins - chemistry | Genetic Vectors - chemistry | Protein Structure, Secondary | Matrix Metalloproteinase 14 - chemistry | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Repressor Proteins - genetics | Recombinant Proteins - genetics | Matrix Metalloproteinase 14 - metabolism | Nephroblastoma Overexpressed Protein - metabolism | Two-Hybrid System Techniques | Escherichia coli - genetics | CCN Intercellular Signaling Proteins - metabolism | Matrix Metalloproteinase 14 - genetics | Protein Binding | HeLa Cells
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2007, Volume 92, Issue 8, pp. 3253 - 3260
Context: Childhood adrenocortical tumors (ACTs) have a fetal adrenal phenotype and overexpress steroidogenic factor-1 (SF-1). Nephroblastoma overexpressed... 
APOPTOSIS | MALIGNANCY | CORTEX | ENDOCRINOLOGY & METABOLISM | MARKERS | RECEPTOR | FETAL ADRENAL-GLAND | PROLIFERATION | DIFFERENTIATION | EXPRESSION | CARCINOMA | Steroidogenic Factor 1 | Adenoma - genetics | Humans | DNA, Complementary - genetics | Apoptosis - genetics | Immunoblotting | Intercellular Signaling Peptides and Proteins - biosynthesis | Receptors, Cytoplasmic and Nuclear - biosynthesis | Adrenal Cortex - cytology | Adenoma - metabolism | Luciferases - genetics | Nephroblastoma Overexpressed Protein | RNA, Messenger - biosynthesis | Caspases - metabolism | Flow Cytometry | Transfection | DNA, Complementary - biosynthesis | Carcinoma - pathology | Child | Gene Expression Regulation, Neoplastic - physiology | Adrenal Cortex Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - genetics | Homeodomain Proteins - biosynthesis | Immediate-Early Proteins - biosynthesis | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Adrenal Cortex - physiology | Transcription Factors - biosynthesis | Receptors, Cytoplasmic and Nuclear - genetics | Adrenal Cortex Neoplasms - pathology | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Down-Regulation - genetics | Homeodomain Proteins - genetics | Adrenal Cortex Neoplasms - genetics | Down-Regulation - physiology | Immediate-Early Proteins - genetics | RNA, Neoplasm - biosynthesis | Fluorescent Antibody Technique | Adenoma - pathology | Cell Line, Tumor | RNA, Neoplasm - genetics | Carcinoma - genetics | Apoptosis - physiology | Carcinoma - metabolism | Enzyme Activation - physiology | Luciferases - biosynthesis | Connective Tissue Growth Factor | Life Sciences | Biochemistry, Molecular Biology | Cancer
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2016, Volume 126, Issue 4, pp. 1282 - 1299
Journal Article