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Journal Article
Journal Article
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 05/2017, Volume 102, Issue 5, pp. 1440 - 1446
Context: The P450 enzyme CYP24A1 is the principal inactivator of vitamin D metabolites. Biallelic loss-of-function mutations in CYP24A1 are associated with... 
THERAPY | GENE | TUBERCULOSIS | ENDOCRINOLOGY & METABOLISM | KETOCONAZOLE | DRUG-INDUCED OSTEOMALACIA | IDIOPATHIC INFANTILE HYPERCALCEMIA | HEPATOTOXICITY | D-3 | Cytochrome P-450 CYP3A Inducers - therapeutic use | Vitamin D3 24-Hydroxylase - genetics | Humans | Male | Parathyroid Hormone - blood | Nephrocalcinosis - etiology | Infant, Newborn, Diseases - drug therapy | Calcium - blood | Hypercalcemia - blood | Female | Hypercalcemia - drug therapy | Infant, Newborn, Diseases - genetics | Rifampin - therapeutic use | Child | Metabolism, Inborn Errors - blood | Hypercalcemia - complications | Hypercalcemia - genetics | Hypercalciuria - etiology | Treatment Outcome | Calcium - urine | Calcitriol - blood | Metabolism, Inborn Errors - genetics | Vitamin D - blood | Infant, Newborn, Diseases - blood | Phosphorus - blood | Adolescent | Metabolism, Inborn Errors - drug therapy | Mutation | Metabolism, Inborn Errors - complications | Calcium | Liver | Calcitriol | Inactivation | Calcium (blood) | Hypercalciuria | Dihydroxyvitamin D3 | Vitamin D | Metabolites | Xenobiotics | Parathyroid | Calcium (urinary) | Enzymes | Excretion | Calcium (dietary) | Nutrient deficiency | Deactivation | Phosphorus | Metabolism | Patients | Mineral metabolism | Hypercalcemia | Serum levels | Diet | Calcinosis | Parathyroid hormone | Kidney diseases | Rifampin | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Archives of Medical Research, ISSN 0188-4409, 2014, Volume 45, Issue 4, pp. 325 - 330
Journal Article
Kidney International, ISSN 0085-2538, 03/2018, Volume 93, Issue 3, pp. 656 - 669
Primary/secondary hyperoxalurias involve nephrocalcinosis-related chronic kidney disease (CKD) leading to end-stage kidney disease. Mechanistically, intrarenal... 
beta-hydroxybutyrate | necroinflammation | fibrosis | crystal nephropathy | NALP3 | OXALATE | REPAIR | DENDRITIC CELLS | RENAL INFLAMMATION | UROLOGY & NEPHROLOGY | MICROENVIRONMENTS | PROGRESSION | Cell Plasticity - drug effects | Inflammasomes - metabolism | Kidney - pathology | Nephrocalcinosis - immunology | Kidney - immunology | Hyperoxaluria - metabolism | Male | CARD Signaling Adaptor Proteins - genetics | Hyperoxaluria - drug therapy | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Renal Insufficiency, Chronic - metabolism | CARD Signaling Adaptor Proteins - metabolism | Kidney - metabolism | Nephrocalcinosis - metabolism | Butylene Glycols - pharmacology | Inflammasomes - drug effects | Interleukin-1 - immunology | Nephrocalcinosis - prevention & control | Female | Macrophages - immunology | Disease Models, Animal | Fibroblasts - metabolism | Interleukin-1 - metabolism | Renal Insufficiency, Chronic - immunology | Macrophages - pathology | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Mice, Inbred C57BL | Cells, Cultured | NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors | Fibroblasts - pathology | Inflammasomes - genetics | Hyperoxaluria - pathology | Mice, Knockout | Renal Insufficiency, Chronic - pathology | Renal Insufficiency, Chronic - prevention & control | Macrophages - metabolism | Nephrocalcinosis - pathology | Phenotype | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Receptors, Transforming Growth Factor beta - metabolism | Inflammasomes - immunology | Fibroblasts - immunology | Macrophages - drug effects | Hyperoxaluria - immunology | End-stage renal disease | Phenotypes | CD11b antigen | Kidneys | Interleukin 1 receptor antagonist | Therapeutic applications | CX3CR1 protein | Inflammation | Macrophages | CD45 antigen | Atrophy | Signal transduction | Calcium oxalate | Oxalic acid | Calcinosis | Interleukin 1 | Fibrosis | Fibroblasts | Hyperoxaluria | Kidney diseases | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 05/2008, Volume 3, Issue 3, pp. 658 - 664
Background and Objectives: The treatment for X-linked hypophosphatemia (XLH) with phosphate and calcitriol can be complicated by secondary hyperparathyroidism... 
PHOSPHATE | VITAMIN-D | CINACALCET HYDROCHLORIDE | FIBROBLAST-GROWTH-FACTOR-23 | TUMOR-INDUCED OSTEOMALACIA | SECONDARY HYPERPARATHYROIDISM | HEMODIALYSIS-PATIENTS | UROLOGY & NEPHROLOGY | PARATHYROID-HORMONE | FGF23 | SERUM PHOSPHORUS | Hyperparathyroidism, Secondary - chemically induced | Potassium Compounds - administration & dosage | Phosphates - administration & dosage | Familial Hypophosphatemic Rickets - drug therapy | Humans | Calcitriol - adverse effects | Familial Hypophosphatemic Rickets - metabolism | Male | Phosphates - therapeutic use | Parathyroid Hormone - blood | Calcitriol - therapeutic use | Calcitriol - administration & dosage | Calcium - blood | Nephrocalcinosis - prevention & control | Phosphates - blood | Female | Drug Therapy, Combination | Genetic Diseases, X-Linked | Child | Hyperparathyroidism, Secondary - prevention & control | Glomerular Filtration Rate | Drug Administration Schedule | Administration, Oral | Familial Hypophosphatemic Rickets - physiopathology | Potassium Compounds - blood | Treatment Outcome | Nephrocalcinosis - chemically induced | Vitamins - therapeutic use | Calcitriol - blood | Vitamins - adverse effects | Cinacalcet Hydrochloride | Phosphates - adverse effects | Fibroblast Growth Factors - blood | Naphthalenes - administration & dosage | Potassium Compounds - adverse effects | Adolescent | Creatinine - blood | Potassium Compounds - therapeutic use | Naphthalenes - therapeutic use | Vitamins - administration & dosage | Index Medicus | Acid | Base and Mineral Metabolism
Journal Article
Journal Article