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American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 07/2012, Volume 303, Issue 2, pp. F209 - F219
Journal Article
11/2010
Hedgehog (HH) signaling controls renal development. Mutations in PTC1, the HH receptor, cause cancer in non-renal tissues. We hypothesized that constitutively... 
0719 | Kidney, Hedgehog, Patched, Mesenchyme, UPJ, Gli, HH, Nephrogenesis
Dissertation
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2017, Volume 28, Issue 11, pp. 3133 - 3135
Journal Article
Biology Open, ISSN 2046-6390, 2019, Volume 8, Issue 5, p. bio042754
Six2 cap mesenchyme cells, also called nephron progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the... 
ChIP-seq | Epigenetics | ATAC-seq | Kidney | Nephrogenesis
Journal Article
Journal of Hypertension, ISSN 0263-6352, 2016, Volume 34, Issue 10, pp. 1988 - 1997
Journal Article
Journal of the American Society of Nephrology : JASN, ISSN 1046-6673, 07/2019, Volume 30, Issue 7, pp. 1192 - 1205
Nephron progenitors, the cell population that give rise to the functional unit of the kidney, are metabolically active and self-renew under glycolytic... 
MORPHOGENESIS | ACTIVATION | NUMBER | NEPHROGENESIS | TRANSCRIPTION | UROLOGY & NEPHROLOGY | SELF-RENEWAL | VHL | KIDNEY | HYPOXIA | SUPPRESSION
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2018, Volume 29, Issue 3, pp. 825 - 840
The nephron is the functional unit of the kidney, but the mechanism of nephron formation during human development is unclear. We conducted a detailed analysis... 
CELLS | MORPHOGENESIS | DEVELOPING KIDNEY | NEPHROGENESIS | METANEPHRIC MESENCHYME | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | DIFFERENTIATION | IDENTIFICATION | EPITHELIAL TRANSFORMATION | EARLY ORGANOGENESIS | nephron | human genetics | kidney development | Basic Research
Journal Article
Andrologiâ i Genitalʹnaâ Hirurgiâ, ISSN 2070-9781, 11/2014, Volume 14, Issue 4, pp. 45 - 48
Kidney biopsies obtained from 3 days – 12 years children with congenital hydronephrosis during nephrectomy operation were investigated under the light... 
nephrogenesis | growth factors | angiogenesis
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 01/2008, Volume 313, Issue 1, pp. 234 - 245
Classic tissue recombination and in vitro lineage tracing studies suggest that condensed metanephric mesenchyme (MM) gives rise to nephronic epithelium of the... 
SYSTEM | cap mesenchyme | NEPHROGENESIS | MOUSE | DISTINCT | CRE RECOMBINASE | metanephric mesenchyme | DEVELOPMENTAL BIOLOGY | lineage tracing | INDUCTION | BMP5 | kidney development | cited1 BAC transgenic mice | GENE-EXPRESSION | EFFICIENT
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 4, pp. 801 - 813
Nephron progenitors in the embryonic kidney propagate while generating differentiated nephrons. However, in mice, the progenitors terminally differentiate... 
NEPHROGENESIS | SIX2 | MAINTAIN | SELF-RENEWAL | MOUSE KIDNEY | DIFFERENTIATION | INDUCTION | MESENCHYME | ORGANOGENESIS | ORGANOIDS | CELL BIOLOGY
Journal Article
Hypertension Research, ISSN 0916-9636, 2019, Volume 42, Issue 6, pp. 779 - 789
We previously reported that rats treated with an NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), during lactation developed hypertension in adult life,... 
nephrogenesis | chronic kidney disease | malignant hypertension | NF-kB system | renal injury | Hypertension | Salt | Breastfeeding & lactation | Kidney diseases | Diet | Rodents
Journal Article
Nature Protocols, ISSN 1754-2189, 09/2016, Volume 11, Issue 9, pp. 1681 - 1692
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2006, Volume 17, Issue 11, pp. 3028 - 3040
Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells. The purpose of this study was to test the hypothesis that renal stem... 
MARROW | REGENERATION | NEPHROGENESIS | POSTISCHEMIC KIDNEY | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | ACUTE-RENAL-FAILURE | ADULT KIDNEY | DIFFERENTIATION | IDENTIFICATION | NEPHRON | Animals | Multipotent Stem Cells - cytology | Rats, Inbred F344 | Cells, Cultured | Rats | Cell Differentiation | Kidney - cytology | Index Medicus
Journal Article
Journal of Anatomy, ISSN 0021-8782, 08/2019, Volume 235, Issue 2, pp. 262 - 270
The path taken by the loop of Henle, from renal cortex to medulla and back, is critical to the ability of the kidney to concentrate urine and recover water.... 
nephrogenesis | kidney development | guidance | tubulogenesis | chemotaxis | ANATOMY & MORPHOLOGY | CELL | CULTURE | DROSOPHILA | Urine | Kidneys | Sodium | Tubules | Loop of Henle | Collecting duct | Epithelium | Renal cortex | Original
Journal Article
Journal Article
Journal Article