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1. Nephroprotective effect of Bauhinia variegata (linn.) whole stem extract against cisplatin-induced nephropathy in rats
by Pani, Saumya R and Mishra, Satyaranjan and Sahoo, Sabuj and Panda, Prasana K
10/2011
The nephroprotective activity of the ethanolic extract of Bauhinia variegata (Linn.) whole stem against cisplatin-induced nephropathy was investigated by an in... 
nephrotoxicity | Kanchana | Cisplatin
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2. Full Text Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective
by Barnett, Lillie M A and Cummings, Brian S
Toxicological Sciences, ISSN 1096-6080, 08/2018, Volume 164, Issue 2, pp. 379 - 390
Abstract The kidney consists of numerous cell types organized into the nephron, which is the basic functional unit of the kidney. Any stimuli that induce loss... 
kidney | Chronic kidney disease | Nephrotoxicity | Acute kidney injury | Renal failure | Renal pathology | RABBIT LIVER-MICROSOMES | chronic kidney disease | DRUG-INDUCED NEPHROTOXICITY | CISPLATIN-INDUCED NEPHROTOXICITY | ORGANIC ANION | PROXIMAL TUBULAR CELLS | DIABETIC-NEPHROPATHY | IN-VITRO | nephrotoxicity | renal failure | acute kidney injury | INORGANIC MERCURY | TOXICOLOGY | BIOMARKERS PREDICT NEPHROTOXICITY | renal pathology
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3. Full Text Metabolomics in Nephrotoxicity
by Zhao, Ying-Yong and Lin, Rui-Chao
2014, Advances in Clinical Chemistry, ISBN 9780128001417, Volume 65, 21
Nephrotoxicity or renal toxicity can be a result of hemodynamic changes, direct injury to cells and tissue, inflammatory tissue injury, and/or obstruction of... 
Metabolomics | Metabonomics | Nuclear magnetic resonance spectroscopy | Renal toxicity | Nephrotoxicity | Kidney injury | Mass spectrometry | GENTAMICIN-INDUCED NEPHROTOXICITY | ACUTE KIDNEY INJURY | MAGNETIC-RESONANCE-SPECTROSCOPY | MORNING GLORY SEED | DRUG-INDUCED NEPHROTOXICITY | LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY | RENAL TOXICITY | CISPLATIN-INDUCED NEPHROTOXICITY | ARISTOLOCHIC ACID | MEDICAL LABORATORY TECHNOLOGY | ACID-INDUCED NEPHROTOXICITY | Animals | Kidney - drug effects | Humans | Immunosuppressive Agents - toxicity | Triazines - toxicity | Antineoplastic Agents - toxicity
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4. Full Text P 197 - Role of mitochondrial NADP+-dependent isocitrate dehydrogenase (IDH2) on cisplatin-induced nephrotoxicity
by Kong, Min Jung and Kim, Jee In and Park, Kwon Moo
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S85 - S85
nephrotoxicity | IDH2 | cisplatin
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5. Full Text The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and Fanconi's syndrome: A comprehensive review
by Heidari, R
TOXICOLOGY, ISSN 0300-483X, 07/2019, Volume 423, pp. 1 - 31
Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule function. FS is associated with a vast defect in the renal reabsorption... 
Energy crisis | Oxidative stress | ACUTE KIDNEY INJURY | CISPLATIN-INDUCED NEPHROTOXICITY | Reabsorption | ACUTE-RENAL-FAILURE | ENDOPLASMIC-RETICULUM STRESS | INDUCED LIVER-INJURY | FUMARIC-ACID ESTERS | Bioenergetics | INDUCED OXIDATIVE STRESS | COLISTIN-INDUCED NEPHROTOXICITY | Defect | PHARMACOLOGY & PHARMACY | IFOSFAMIDE-INDUCED NEPHROTOXICITY | TOXICOLOGY | ACUTE INTERSTITIAL NEPHRITIS | ATP | Nephrotoxicity | Xenobiotics | Electrolytes
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6. Full Text The potential use of natural products to negate hepatic, renal and neuronal toxicity induced by cancer therapeutics
by Prša, Patrik and Karademir, Betül and Biçim, Gökhan and Mahmoud, Hatem and Dahan, Inbal and Yalçın, A Süha and Mahajna, Jamal and Milisav, Irina
Biochemical pharmacology, ISSN 0006-2952, 06/2019
Different types of chemotherapeutics are used for cancer treatment. These drugs act on several signal pathways, lead to programmed cell death, and damage... 
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7. Amelioration of Cisplatin-Induced Nephrotoxicity in Rats by Curcumin and α-Tocopherol
by Palipoch, Sarawoot and Punsawad, Chuchard and Chinnapun, Dutsadee and Suwannalert, Prasit
01/2014
Purpose: To investigate the possible protective role of curcumin and α-tocopherol against cisplatin-induced nephrotoxicity in rat. Methods: Male Wistar rats... 
Oxidative stress | α-Tocopherol | Curcumin | Nephrotoxicity | Cisplatin
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8. Full Text Evaluation of Novel Acute Urinary Rat Kidney Toxicity Biomarker for Subacute Toxicity Studies in Preclinical Trials
by Fuchs, Tobias Christian and Frick, Katharina and Emde, Barbara and Czasch, Stephanie and Landenberg, Friedrich von and Hewitt, Philip
Toxicologic Pathology, ISSN 0192-6233, 10/2012, Volume 40, Issue 7, pp. 1031 - 1048
Novel urinary protein biomarkers for the detection of acute renal damage, recently accepted by the U.S. Food and Drug Administration, European Medicines... 
nephrotoxicity | 28-day toxicity study | puromycin | urinary biomarkers | vancomycin | multiplexed analyte profiling | cisplatin | CYCLOSPORINE NEPHROTOXICITY | ACUTE-RENAL-FAILURE | GLUTATHIONE S-TRANSFERASES | GELATINASE-ASSOCIATED LIPOCALIN | PATHOLOGY | CISPLATIN NEPHROTOXICITY | INJURY MOLECULE-1 | CADMIUM NEPHROTOXICITY | CYSTATIN-C | TOXICOLOGY | INDUCED NEPHROTOXICITY | ENDOTHELIAL GROWTH-FACTOR | Acute Disease | Biomarkers - urine | Rats, Wistar | Kidney Diseases - pathology | Rats | Male | Xenobiotics - toxicity | Kidney Diseases - urine | Puromycin - toxicity | Dose-Response Relationship, Drug | Animals | Cisplatin - toxicity | Vancomycin - toxicity | Antimetabolites, Antineoplastic - toxicity | Kidney Diseases - chemically induced | Female | Anti-Bacterial Agents - toxicity | Drug Evaluation, Preclinical | Toxicity Tests, Subacute - methods
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9. Full Text Etiología de la insuficiencia renal en pacientes con endocarditis infecciosa. Papel de los antibióticos
by Goenaga Sánchez, Miguel Ángel and Kortajarena Urkola, Xabier and Bouza Santiago, Emilio and Muñoz García, Patricia and Verde Moreno, Eduardo and Fariñas Álvarez, M. Carmen and Teira Cobo, Ramón and Pericás Pulido, Juan Manuel and de Alarcón González, Arístides and Sousa Regueiro, Dolores and Ruiz Morales, Josefa and Rodríguez-Álvarez, Regino José and Antorrena Miranda, Isabel and Iribarren Loyarte, José Antonio
Medicina Clinica, ISSN 0025-7753, 10/2017, Volume 149, Issue 8, pp. 331 - 338
Background and objectives The possible renal toxicity of certain antibiotics (AB) is well known. The objective of our work is to know the possible effect of AB... 
Antibiotics | Infectious endocarditis | Nephrotoxicity
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10. Drug-induced nephrotoxicity: Pathogenic mechanisms, biomarkers and prevention strategies
by Wu, Huizi and Huang, Jiaguo
Current Drug Metabolism, ISSN 1389-2002, 2018, Volume 19, Issue 7, pp. 559 - 567
Background: Risk factors of drug-induced nephrotoxicity include drug overdose, drug-drug interactions and drug-related adverse effects. Since the usage of some... 
Biomarkers | Early diagnosis | Chronic kidney disease (CKD) | Kidney function | Drug-induced nephrotoxicity | Acute kidney injury (AKI) | GENTAMICIN-INDUCED NEPHROTOXICITY | acute kidney injury (AKI) | kidney function | biomarkers | VANCOMYCIN-INDUCED NEPHROTOXICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-D-GLUCOSAMINIDASE | ACUTE-RENAL-FAILURE | GELATINASE-ASSOCIATED LIPOCALIN | AMPHOTERICIN-B | chronic kidney disease (CKD) | early diagnosis | CELL-CULTURE MODELS | PHARMACOLOGY & PHARMACY | CYCLOSPORINE-INDUCED NEPHROTOXICITY | CONTRAST-INDUCED NEPHROPATHY | CHRONIC KIDNEY-DISEASE | Drugs | Kidneys | Impairment | Drug overdose | Drug development | Risk analysis | Risk factors | Prevention | Side effects | Injury prevention | Developmental stages | Renal failure | Overdose | Bioindicators | Diagnostic systems
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11. Full Text Reno-protective effect of linagliptin against gentamycin nephrotoxicity in rats
by Helmy, Mai M and Mouneir, Samar M
Pharmacological Reports, ISSN 1734-1140, 07/2019
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12. Full Text A clinical pharmacist survey of prophylactic strategies used to prevent adverse events of lipid-associated formulations of amphotericin B
by Chastain, Daniel B and Giles, Rachele L and Bland, Christopher M and Franco-Paredes, Carlos and Henao-Martínez, Andrés F and Young, Henry N
Infectious Diseases, ISSN 2374-4235, 05/2019, Volume 51, Issue 5, pp. 380 - 383
INFECTIOUS DISEASES | INFUSION | LIPOSOME | NEPHROTOXICITY
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13. Full Text Adverse effects of aminoglycosides in children with drug resistant tuberculosis
by Shah, Ira and Goyal, Anmol and Shetty, Naman S
Infectious Diseases, ISSN 2374-4235, 03/2019, Volume 51, Issue 3, pp. 230 - 233
HEARING-LOSS | INFECTIOUS DISEASES | NEPHROTOXICITY
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14. Full Text Vancomycin and the risk of AKI: Now clearer than mississippi mud
by Nolin, Thomas D
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 2016, Volume 11, Issue 12, pp. 2101 - 2103
Acute Kidney Injury | Mississippi | Drug nephrotoxicity | Risk | Vancomycin | Nephrotoxicity | Acute renal failure | UROLOGY & NEPHROLOGY | HOSPITALIZED-PATIENTS | ACUTE-RENAL-FAILURE | INDUCED NEPHROTOXICITY | AMINOGLYCOSIDE | Anti-Bacterial Agents | Humans | acute renal failure | nephrotoxicity | vancomycin | drug nephrotoxicity
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15. Full Text Role of nigella sativa and its constituent thymoquinone on chemotherapy-induced nephrotoxicity: Evidences from experimental animal studies
by Cascella, Marco and Palma, Giuseppe and Barbieri, Antonio and Bimonte, Sabrina and Amruthraj, Nagoth Joseph and Muzio, Maria Rosaria and del Vecchio, Vitale and Rea, Domenica and Falco, Michela and Luciano, Antonio and Arra, Claudio and Cuomo, Arturo
Nutrients, ISSN 2072-6643, 06/2017, Volume 9, Issue 6, p. 625
Background: Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore, new strategies have been considered to prevent chemotherapy-induced... 
Natural compounds | Nigella sativa | Chemotherapy-induced nephrotoxicity | Thymoquinone | GENTAMICIN-INDUCED NEPHROTOXICITY | natural compounds | DOXORUBICIN-INDUCED NEPHROTOXICITY | chemotherapy-induced nephrotoxicity | CISPLATIN-INDUCED NEPHROTOXICITY | RATS | TOXICITY | IFOSFAMIDE | IN-VITRO | NUTRITION & DIETETICS | OIL | FANCONI SYNDROME | PROTECTIVE ROLE | Animals | Antineoplastic Agents - adverse effects | Nigella sativa - chemistry | Kidney Diseases - chemically induced | Kidney Diseases - drug therapy | Benzoquinones - chemistry | Phytotherapy | Benzoquinones - therapeutic use | Kidneys | Ifosfamide | Complications | Lipid peroxidation | Data processing | Systematic review | Doxorubicin | Cisplatin | Antioxidants | Literature reviews | Chemotherapy | Databases | Reviews | Animal tissues | Design standards | Methotrexate | Peroxidation
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16. Full Text The nephrotoxicity of concurrent use of enalapril and gentamicin in rats
by Al-Ani, Imad M and Algantri, Khaleed R and Nafie, Emad M and Al-Mahmood, Sinan Mohammed Abdullah
Asian Journal of Pharmaceutical and Clinical Research, ISSN 0974-2441, 09/2018, Volume 11, Issue 9, pp. 348 - 352
Objective: The present study was aimed to assess the concurrent administration of Enalapril (ENAL) and Gentamicin (GM) in the kidney of rats.Methods: Sixty... 
Enalapril | Nephrotoxicity | Concurrent | Gentamicin
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17. Diclofenac-induced biochemical and histopathological changes in white leghorn birds ( Gallus domesticus )
by Jain, Teenu and Koley, K. M and Vadlamudi, V. P and Ghosh, R. C and Roy, S and Tiwari, Sandhya and Sahu, Upasana
11/2010
Objective : To evaluate diclofenac-induced biochemical and histopathological changes in White Leghorn birds. Materials and Methods : Six-week-old birds were... 
White Leghorn birds | nephrotoxicity | visceral gout | Diclofenac
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18. Full Text Time-Dependent Alterations of Vancomycin-Induced Nephrotoxicity in Mice
by Masaki Takigawaa and b and Hirofumi Masutomia and Yuki Kishimotoa and † and Yoshitomo Shimazakia and Yoshitomo Hamanoc and Yoshitaka Kondoa and Tomio Araid and Jaewon Leee and Toshihiro Ishiif and Yoshiko Morib and Akihito Ishigamia and National Institute of Health and dDepartment of Pathology and Pusan National University and aMolecular Regulation of Aging and eDepartment of Pharmacy and Faculty of Pharmaceutical Sciences and bDepartment of Pharmacy and Toho University and National Institute on Aging and Present address : Laboratory of Neuroscience (LNS and Tokyo Metropolitan Geriatric Hospital and cDepartment of Nephrology and Tokyo Metropolitan Institute of Gerontology and Biomedical Research Center (BRC and fDepartment of Practical Pharmacy
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 7, pp. 975 - 983
Vancomycin hydrochloride (VCM) is a glycopeptide antibiotic that is commonly used against methicillin-resistant, Gram-positive cocci despite the nephrotoxic... 
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19. Full Text Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice
by Zhang, Yong and Chi, Xiaoqing and Wang, Yuemin and Wang, Zizengchen and Wang, Huanan and Bi, Shicheng and Shi, Fushan and Hu, Songhua
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 08/2019, Volume 116, pp. 108970 - 108970
Polymyxin E (PME) plays an important role in fighting against Gram-negative bacterial infections; however, it causes nephrotoxicity, which limits its clinical... 
Oxidative stress | Panax notoginseng saponins (PNS) | Nephrotoxicity | Polymyxin E (PME) | Apoptosis | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED APOPTOSIS | MITOCHONDRIAL | RENAL TUBULAR CELLS | CISPLATIN-INDUCED NEPHROTOXICITY | COLISTIN-INDUCED NEPHROTOXICITY | PHARMACOLOGY & PHARMACY | ASCORBIC-ACID PROTECTS | POLYMYXIN | ACCUMULATION | SULFATE-INDUCED NEUROTOXICITY
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20. Protective effect of Kalanchoe pinnata   pers. (Crassulaceae   ) on gentamicin-induced nephrotoxicity in rats
by Harlalka, Gaurav Vijay and Patil, Chandragauda Raosaheb and Patil, Mahesh Ramu
02/2008
Objective : The present study was undertaken to evaluate the aqueous extract of K. pinnata for its protective effects on gentamicin-induced nephrotoxicity in... 
nephrotoxicity | gentamicin | Bryophyllum pinnata | Antioxidant
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