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Journal Article
Epilepsia, ISSN 0013-9580, 03/2014, Volume 55, Issue 3, pp. 414 - 422
Journal Article
Neuroscience, ISSN 0306-4522, 2010, Volume 166, Issue 2, pp. 464 - 475
Abstract Damage to oligodendrocyte (OL) progenitor cells (OPCs) and hypomyelination are two hallmark features of periventricular leukomalacia (PVL), the most... 
Neurology | myelin | cytokine | nitric oxide | TNF-α | reactive oxygen species | Reactive oxygen species | Myelin | Nitric oxide | Cytokine | APOPTOSIS | TNF-alpha | BRAIN-INJURY | PERIVENTRICULAR LEUKOMALACIA | TOXICITY | RELEASE | NEUROSCIENCES | TUMOR-NECROSIS-FACTOR | IN-VITRO | GLUTAMATE | NITRIC-OXIDE | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Oligodendroglia - metabolism | Stem Cells - immunology | Reactive Oxygen Species - metabolism | Ciliary Neurotrophic Factor - immunology | Cell Death - immunology | Oxidative Stress - immunology | Stem Cells - metabolism | Lipopolysaccharides - immunology | Insulin-Like Growth Factor I - immunology | Oligodendroglia - immunology | Microglia - immunology | Reactive Oxygen Species - immunology | Nerve Growth Factor - immunology | Tumor Necrosis Factor-alpha - immunology | Nerve Fibers, Myelinated - metabolism | Nerve Growth Factor - metabolism | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Cells, Cultured | Rats | Cell Survival - immunology | Blotting, Western | Cell Differentiation - immunology | Ciliary Neurotrophic Factor - metabolism | Animals | Analysis of Variance | Lipopolysaccharides - pharmacology | Nerve Fibers, Myelinated - immunology | Nitric Oxide - metabolism | Insulin-Like Growth Factor I - metabolism | Cell Lineage - immunology | Neurosciences | Brain damage | Lactate dehydrogenase | Serum albumin | Fibroblast growth factors | Peptide hormones | Ciliary neurotrophic factor | Intermediate filament proteins | Mitogens | Myelin proteins | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2009, Volume 119, Issue 12, pp. 3678 - 3691
Adult neural stem cells (aNSCs) derived from the subventricular zone of the brain show therapeutic effects in EAE, an animal model of the chronic inflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | FUNCTIONAL RECOVERY | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | NEUROTROPHIC FACTOR | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | INFECTIOUS TOLERANCE | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | T-LYMPHOCYTES | TRANSGENIC MICE | Fas Ligand Protein - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Multipotent Stem Cells - immunology | Neurons - cytology | Green Fluorescent Proteins - genetics | fas Receptor - metabolism | Adult Stem Cells - immunology | Neurons - transplantation | Time Factors | Nerve Fibers, Myelinated - pathology | Multipotent Stem Cells - transplantation | Female | Cell Differentiation | T-Lymphocytes - pathology | Adult Stem Cells - transplantation | Adult Stem Cells - cytology | Encephalomyelitis, Autoimmune, Experimental - pathology | Transduction, Genetic | Immunomodulation | Mice, Inbred C57BL | Neurons - immunology | Mice, Transgenic | Recombinant Proteins - genetics | Encephalomyelitis, Autoimmune, Experimental - therapy | Animals | Genetic Engineering | Multipotent Stem Cells - cytology | Interleukin-10 - genetics | Nerve Fibers, Myelinated - immunology | Interleukin-10 - biosynthesis | T-Lymphocytes - immunology | Mice | In Vitro Techniques | Apoptosis | Encephalitis | Nervous system diseases | Cytokines | Neurons | Analysis | Stem cells | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0170847 - e0170847
Background Optic neuritis (ON) in patients with anti-myelin oligodendrocyte glycoprotein (MOG)-IgG antibodies has been associated with a better clinical... 
ANTIBODIES | NMO | MULTIPLE-SCLEROSIS | MYELIN-OLIGODENDROCYTE GLYCOPROTEIN | NEUROMYELITIS-OPTICA | MULTIDISCIPLINARY SCIENCES | SPECTRUM DISORDERS | HAND MOTION | COUNTING FINGERS | COHERENCE TOMOGRAPHY | VISUAL-ACUITY TEST | Myelin-Oligodendrocyte Glycoprotein - immunology | Optic Nerve - diagnostic imaging | Myelin-Oligodendrocyte Glycoprotein - genetics | Optic Nerve - pathology | Gene Expression | Aquaporin 4 - immunology | Tomography, Optical Coherence | Humans | Middle Aged | Optic Neuritis - diagnostic imaging | Autoantibodies - biosynthesis | Visual Acuity | Immunoglobulin G - biosynthesis | Nerve Fibers, Myelinated - pathology | Visual Fields | Nerve Fibers, Myelinated - immunology | Aquaporin 4 - genetics | Optic Nerve - immunology | Adult | Female | Retrospective Studies | Optic Neuritis - pathology | Child | Optic Neuritis - immunology | Physiological aspects | Care and treatment | Optic nerve | Properties | Immunoglobulin G | Optic neuritis | Aquaporin 4 | Multiple sclerosis | Correlation | Oligodendrocyte-myelin glycoprotein | Antibodies | Optics | Retina | Systematic review | Epidemiology | Visual perception | Acuity | Eye | Immunology | Medical laboratories | Tomography | Neuritis | Eye (anatomy) | Ophthalmology | Drug dosages | Visual fields | Edema | Immunoglobulins | Myelin | Visual field | Aquaporins | Glycoprotein | Visual acuity | Preventive medicine | Patients | Thickness | Neurology | Index Medicus
Journal Article
Journal Article
Journal of Neuropathology and Experimental Neurology, ISSN 0022-3069, 05/2008, Volume 67, Issue 5, pp. 388 - 401
The roles of plasmacytoid dendritic cells (pDCs) and their response to interferon (IFN)-β therapy in multiple sclerosis (MS) patients are poorly understood. We... 
IFN-β therapy | Multiple sclerosis | Plasmacytoid dendritic cells | ACTIVATION | multiple sclerosis | SUBSETS | LUPUS-ERYTHEMATOSUS | PATHOLOGY | IFN-beta therapy | NEUROSCIENCES | LESIONS | CLINICAL NEUROLOGY | I INTERFERON | plasmacytoid dendritic cells | IMMUNE-RESPONSES | REGULATORY T-CELLS | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | EPSTEIN-BARR-VIRUS | GTP-Binding Proteins - drug effects | Dendritic Cells - immunology | Humans | Middle Aged | Chemokines - drug effects | Male | Nerve Fibers, Myelinated - ultrastructure | Antigens, CD - metabolism | Cerebral Cortex - physiopathology | Antigens, CD - analysis | Interferon-beta - therapeutic use | Plasma Cells - drug effects | Multiple Sclerosis - physiopathology | Lymphocyte Activation - immunology | Myxovirus Resistance Proteins | Lymphocytes - immunology | Chemotaxis, Leukocyte - drug effects | Adult | Dendritic Cells - drug effects | Female | Cerebral Cortex - drug effects | Chemokines - immunology | Biomarkers - metabolism | GTP-Binding Proteins - immunology | B7-H1 Antigen | Intercellular Signaling Peptides and Proteins | Nerve Fibers, Myelinated - drug effects | Biomarkers - analysis | Cell Differentiation - immunology | Phenotype | Interferon-beta - pharmacology | Cell Differentiation - drug effects | Cerebral Cortex - immunology | Lymphocyte Activation - drug effects | Lymphocytes - drug effects | Nerve Fibers, Myelinated - immunology | Multiple Sclerosis - immunology | Chemotaxis, Leukocyte - immunology | Immunologic Factors - pharmacology | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Plasma Cells - immunology | Index Medicus
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 04/2007, Volume 85, Issue 5, pp. 967 - 976
A recombinant human monoclonal IgM, rHIgM22, promotes the synthesis of new myelin when used to treat several animal models of demyelination. rHIgM22 binds to... 
spinal cord repair | multiple sclerosis | Theiler's murine encephalomyelitis virus | oligodendrocyte | Multiple sclerosis | Oligodendrocyte | Spinal cord repair | PROGENITOR CELLS | MULTIPLE-SCLEROSIS LESIONS | CNS REMYELINATION | OLIGODENDROCYTE PRECURSOR CELLS | SPINAL-CORD | NEUROSCIENCES | FIBROBLAST-GROWTH | LYSOLECITHIN-INDUCED DEMYELINATION | MOUSE MODEL | EXTENSIVE DEMYELINATION | NERVOUS-SYSTEM REMYELINATION | Antibody Specificity | Spinal Cord - drug effects | Recombinant Fusion Proteins - pharmacology | Recovery of Function - drug effects | Humans | Recombinant Fusion Proteins - therapeutic use | Nerve Regeneration - immunology | Myelin Sheath - drug effects | Metabolic Clearance Rate | Central Nervous System - immunology | Dose-Response Relationship, Drug | Multiple Sclerosis - physiopathology | Nerve Fibers, Myelinated - pathology | Demyelinating Diseases - immunology | Female | Demyelinating Diseases - drug therapy | Disease Models, Animal | Demyelinating Diseases - physiopathology | Microscopy, Electron, Transmission | Drug Administration Schedule | Myelin Sheath - immunology | Myelin Sheath - pathology | Nerve Fibers, Myelinated - drug effects | Rats | Treatment Outcome | Spinal Cord - immunology | Recovery of Function - immunology | Animals | Immunoglobulin M - blood | Nerve Fibers, Myelinated - immunology | Nerve Regeneration - drug effects | Central Nervous System - drug effects | Multiple Sclerosis - immunology | Mice | Spinal Cord - physiopathology | Central Nervous System - physiopathology | Immunoglobulin M - pharmacology | Multiple Sclerosis - drug therapy | Index Medicus
Journal Article
Journal of Neurotrauma, ISSN 0897-7151, 09/2011, Volume 28, Issue 9, pp. 1893 - 1907
Journal Article