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Nature, ISSN 0028-0836, 07/2010, Volume 466, Issue 7302, pp. 133 - 137
The question of whether tumorigenic cancer stem cells exist in human melanomas has arisen in the last few years(1). Here we show that in melanomas, tumour stem... 
PROGENITORS | PROSPECTIVE IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | CANCER STEM-CELLS | Bone and Bones - pathology | Neoplasm Transplantation | Neoplastic Stem Cells - cytology | Humans | Nerve Tissue Proteins - deficiency | Neural Crest - pathology | Receptors, Nerve Growth Factor - metabolism | Neoplasm Proteins - metabolism | DNA-Binding Proteins - deficiency | Neural Crest - metabolism | Neoplasm Metastasis | Lung Neoplasms - secondary | Neoplastic Stem Cells - metabolism | Antigens, Neoplasm - metabolism | Neoplastic Stem Cells - pathology | Skin Transplantation | Antigens, Neoplasm - analysis | Skin - pathology | Melanoma - metabolism | Melanoma-Specific Antigens | Neural Crest - cytology | Melanoma - pathology | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Neoplastic Stem Cells - transplantation | Receptors, Nerve Growth Factor - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Bone Transplantation | Neoplasm Proteins - analysis | Transplantation, Heterologous - pathology | Mice | Receptors, Nerve Growth Factor - deficiency | Care and treatment | Melanoma | Stem cells | Physiological aspects | Development and progression | Nerve growth factor | Genetic aspects | Growth factor receptors | Research | Risk factors | Transplants & implants | Skin & tissue grafts | Cancer | Tumors | Human | Enrichment | Antigens | Tumours | Bones | Transplantation
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1298 - 1311
Idiopathic pulmonary fibrosis (IPF) can lead to the development of secondary pulmonary hypertension (PH) and ultimately death. Despite this known association,... 
MEDICINE, RESEARCH & EXPERIMENTAL | EPITHELIUM-DERIVED FACTOR | GROWTH-FACTOR-BETA | ANGIOGENESIS | ARTERIAL-HYPERTENSION | DISEASE | SMOOTH-MUSCLE-CELLS | PROLIFERATION | GENE-TRANSFER | EXPRESSION | PIGMENT-EPITHELIUM | Genetic Therapy | Idiopathic Pulmonary Fibrosis - therapy | Apoptosis - drug effects | Gene Expression - genetics | Humans | Transforming Growth Factor beta1 - metabolism | Caspase 3 - metabolism | Hypertension, Pulmonary - physiopathology | Microvessels - pathology | Idiopathic Pulmonary Fibrosis - chemically induced | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Hypertension, Pulmonary - therapy | Idiopathic Pulmonary Fibrosis - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Pulmonary Artery - metabolism | Idiopathic Pulmonary Fibrosis - complications | Vascular Endothelial Growth Factor A - pharmacology | Transforming Growth Factor beta1 - pharmacology | Disease Models, Animal | Fibroblasts - metabolism | Serpins - genetics | Endothelial Cells - metabolism | Smad2 Protein - metabolism | Rats | Lung - physiopathology | Nitric Oxide Synthase Type III - genetics | Rats, Sprague-Dawley | Eye Proteins - metabolism | Models, Biological | Nerve Growth Factors - genetics | Fibroblasts - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Bronchoalveolar Lavage Fluid - chemistry | Hypertension, Pulmonary - etiology | Serum Albumin - metabolism | Phosphorylation | Female | Lung - metabolism | Eye Proteins - genetics | Lung - pathology | Serpins - metabolism | Vascular Endothelial Growth Factor A - therapeutic use | Microvessels - drug effects | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Transforming Growth Factor beta1 - genetics | Animals | Endothelial Cells - cytology | Pulmonary Artery - pathology | Endothelial Cells - drug effects | Immunohistochemistry | Usage | Care and treatment | Genetic aspects | Research | Health aspects | Vascular endothelial growth factor | Pulmonary hypertension | Risk factors | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Annual Review of Neuroscience, ISSN 0147-006X, 7/2017, Volume 40, Issue 1, pp. 307 - 325
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 7/2009, Volume 58, Issue 7, pp. 1033 - 1045
Lenalidomide (Revlimid®; CC-5013) and pomalidomide (CC-4047) are IMiDs® proprietary drugs having immunomodulatory properties that have both shown activity in... 
Immunomodulatory drugs | Biomedicine | Immunology | Lenalidomide | T regulatory cells | Cancer Research | Oncology | Pomalidomide | IMiDs | MULTIPLE-MYELOMA | DENILEUKIN DIFTITOX | THERAPEUTIC IMPLICATIONS | IMiDs (R) | PERIPHERAL-BLOOD | IMMUNOLOGY | TUMOR-INFILTRATING LYMPHOCYTES | CANCER-PATIENTS | ONCOLOGY | IN-VIVO | THALIDOMIDE ANALOG | ANTITUMOR IMMUNITY | Forkhead Transcription Factors - immunology | Receptors, Nerve Growth Factor - immunology | Receptors, Transforming Growth Factor beta - immunology | Receptors, Nerve Growth Factor - drug effects | Humans | Receptors, Nerve Growth Factor - metabolism | Thalidomide - pharmacology | Colonic Neoplasms - metabolism | Receptors, OX40 - immunology | T-Lymphocytes, Regulatory - immunology | Thalidomide - analogs & derivatives | Receptors, OX40 - metabolism | Transforming Growth Factor beta - drug effects | Colonic Neoplasms - immunology | Forkhead Transcription Factors - metabolism | Interleukin-10 - metabolism | Female | Antineoplastic Agents - pharmacology | Forkhead Transcription Factors - antagonists & inhibitors | Immunosuppressive Agents - pharmacology | Receptors, Tumor Necrosis Factor - metabolism | Transforming Growth Factor beta - immunology | Glucocorticoid-Induced TNFR-Related Protein | T-Lymphocytes, Regulatory - drug effects | Animals | Receptors, Transforming Growth Factor beta - drug effects | Receptors, Transforming Growth Factor beta - metabolism | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Receptors, Tumor Necrosis Factor - immunology | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Receptors, Tumor Necrosis Factor - drug effects | Receptors, OX40 - antagonists & inhibitors | Care and treatment | Dexamethasone | Multiple myeloma | Angiogenesis inhibitors | Transforming growth factors | T cells | Cancer
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 05/2013, Volume 138, Issue 2, pp. 155 - 175
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are important for... 
Parkinson's | GDNF | NGF | Trk | BDNF | Alzheimer's | FOREBRAIN CHOLINERGIC NEURONS | NERVE-GROWTH-FACTOR | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROTROPHIC FACTOR GDNF | NIGRAL DOPAMINERGIC-NEURONS | MOUSE MODEL | PHARMACOLOGY & PHARMACY | BASAL FOREBRAIN | LONG-TERM POTENTIATION | CONVECTION-ENHANCED DELIVERY | UP-REGULATES BDNF | Humans | Models, Molecular | Nerve Growth Factors - administration & dosage | Nerve Growth Factors - chemistry | Nerve Growth Factors - metabolism | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - drug therapy | Glial Cell Line-Derived Neurotrophic Factor - administration & dosage | Nerve Growth Factors - therapeutic use | Brain-Derived Neurotrophic Factor - administration & dosage | Brain-Derived Neurotrophic Factor - chemistry | Glial Cell Line-Derived Neurotrophic Factor - metabolism | Animals | Glial Cell Line-Derived Neurotrophic Factor - therapeutic use | Ligands | Brain-Derived Neurotrophic Factor - metabolism | Brain-Derived Neurotrophic Factor - therapeutic use | Glial Cell Line-Derived Neurotrophic Factor - chemistry | Brain | Enzymes | Care and treatment | Inositol | Glycogen | Tissue plasminogen activator | Amyloid beta-protein | Amyotrophic lateral sclerosis | Nerve growth factor | Superoxide | Apolipoproteins | Transforming growth factors | Synthesis | Choline | Bone morphogenetic proteins | Dopa | Alzheimer's disease | Intermediate filament proteins | Injuries | Protein binding
Journal Article