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1. Full Text GDNF, NGF and BDNF as therapeutic options for neurodegeneration
by Allen, Shelley J and Watson, Judy J and Shoemark, Deborah K and Barua, Neil U and Patel, Nikunj K
Pharmacology and Therapeutics, ISSN 0163-7258, 05/2013, Volume 138, Issue 2, pp. 155 - 175
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are important for... 
Parkinson's | GDNF | NGF | Trk | BDNF | Alzheimer's | FOREBRAIN CHOLINERGIC NEURONS | NERVE-GROWTH-FACTOR | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROTROPHIC FACTOR GDNF | NIGRAL DOPAMINERGIC-NEURONS | MOUSE MODEL | PHARMACOLOGY & PHARMACY | BASAL FOREBRAIN | LONG-TERM POTENTIATION | CONVECTION-ENHANCED DELIVERY | UP-REGULATES BDNF | Humans | Models, Molecular | Nerve Growth Factors - administration & dosage | Nerve Growth Factors - chemistry | Nerve Growth Factors - metabolism | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - drug therapy | Glial Cell Line-Derived Neurotrophic Factor - administration & dosage | Nerve Growth Factors - therapeutic use | Brain-Derived Neurotrophic Factor - administration & dosage | Brain-Derived Neurotrophic Factor - chemistry | Glial Cell Line-Derived Neurotrophic Factor - metabolism | Animals | Glial Cell Line-Derived Neurotrophic Factor - therapeutic use | Ligands | Brain-Derived Neurotrophic Factor - metabolism | Brain-Derived Neurotrophic Factor - therapeutic use | Glial Cell Line-Derived Neurotrophic Factor - chemistry | Brain | Enzymes | Care and treatment | Inositol | Glycogen | Tissue plasminogen activator | Amyloid beta-protein | Amyotrophic lateral sclerosis | Nerve growth factor | Superoxide | Apolipoproteins | Transforming growth factors | Synthesis | Choline | Bone morphogenetic proteins | Dopa | Alzheimer's disease | Intermediate filament proteins | Injuries | Protein binding
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2. Full Text The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential
by Becerra, SP and Notario, V
NATURE REVIEWS CANCER, ISSN 1474-175X, 04/2013, Volume 13, Issue 4, pp. 258 - 271
The potent actions of pigment epithelium-derived factor (PEDF) on tumour-associated cells, and its extracellular localization and secretion, stimulated... 
ORTHOTOPIC OSTEOSARCOMA GROWTH | EPITHELIUM-DERIVED FACTOR | ADIPOSE TRIGLYCERIDE LIPASE | ONCOLOGY | MEDIATED GENE-TRANSFER | FACTOR INHIBITS ANGIOGENESIS | ANTI-ANGIOGENIC ACTIVITY | TUMOR-GROWTH | ENDOTHELIAL GROWTH-FACTOR | CEREBELLAR GRANULE CELLS | RETINAL-PIGMENT EPITHELIUM | Neoplasms - metabolism | Serpins - metabolism | Humans | Neoplasms - blood supply | Nerve Growth Factors - metabolism | Eye Proteins - therapeutic use | Serpins - therapeutic use | Angiogenesis Inhibitors | Serpins - physiology | Neoplasms - drug therapy | Nerve Growth Factors - therapeutic use | Eye Proteins - metabolism | Cell Differentiation | Eye Proteins - physiology | Nerve Growth Factors - physiology | Protease Inhibitors - therapeutic use | Physiological aspects | Genetic aspects | Research | Retinal pigment epithelium | Cancer
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3. Full Text Unconventional neurotrophic factors CDNF and MANF: structure, physiological functions and therapeutic potential
by Lindahl, Maria and Saarma, Mart and Lindholm, Päivi
Neurobiology of Disease, ISSN 0969-9961, 2016, Volume 97, Issue Pt B, pp. 90 - 102
Abstract Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) promote the survival of midbrain... 
Neurology | ER stress | Parkinson's disease | Diabetes | CDNF | MANF | NERVE REGENERATION | ENDOPLASMIC-RETICULUM STRESS | NEUROSCIENCES | RAT MODEL | DIABETES-MELLITUS | UNFOLDED PROTEIN RESPONSE | MIDBRAIN DOPAMINE NEURONS | CONVECTION-ENHANCED DELIVERY | INTRACELLULAR TRAFFICKING | TRANSMEMBRANE PROTEIN | Neuroprotective Agents - therapeutic use | Animals | Neuroprotective Agents - chemistry | Nerve Growth Factors - genetics | Humans | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Nerve Growth Factors - chemistry | Nerve Growth Factors - metabolism | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - drug therapy | Nerve Growth Factors - therapeutic use | Proteins | Physiological aspects | Nervous system diseases | Health aspects | Analysis
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4. Neurotrophic factors
by Aebischer, P and Hefti, Franz
1998, Handbook of experimental pharmacology, ISBN 9783540646143, Volume 134., xviii, 325
Nerve growth factor | Nervous system | Neurotrophic functions | Diseases
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5. Full Text Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease
by Tuszynski, Mark H and Yang, Jennifer H and Barba, David and U, Hoi-Sang and Bakay, Roy A. E and Pay, Mary M and Masliah, Eliezer and Conner, James M and Kobalka, Peter and Roy, Subhojit and Nagahara, Alan H
JAMA Neurology, ISSN 2168-6149, 10/2015, Volume 72, Issue 10, pp. 1139 - 1147
IMPORTANCE: Alzheimer disease (AD) is the most common neurodegenerative disorder and lacks effective disease-modifying therapies. In 2001, we initiated a... 
CLINICAL IMPROVEMENT | NUCLEUS BASALIS | ATROPHY | BASAL FOREBRAIN | SPATIAL MEMORY | NGF | MPTP-LESIONED PRIMATES | BRAIN | CLINICAL NEUROLOGY | DEGENERATION | DELIVERY | Gene Transfer Techniques | Genetic Therapy | Humans | Middle Aged | Alzheimer Disease - therapy | Male | Nerve Degeneration - metabolism | Nerve Growth Factor - therapeutic use | Brain - drug effects | Brain - metabolism | Autopsy | Female | Aged | Neurons - metabolism | Alzheimer Disease - genetics | Neurons - drug effects
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6. Full Text The GDNF family: Signalling, biological functions and therapeutic value
by Saarma, Mart and Airaksinen, Matti S
Nature Reviews Neuroscience, ISSN 1471-003X, 05/2002, Volume 3, Issue 5, pp. 383 - 394
Members of the nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) families - comprising neurotrophins and GDNF-family ligands... 
PRIMARY AFFERENTS | ENTERIC NERVOUS-SYSTEM | NEUROTROPHIC FACTOR | LIPID RAFTS | SYMPATHETIC NEURONS | HIRSCHSPRUNG-DISEASE | DOPAMINERGIC-NEURONS | RET RECEPTOR | NEUROSCIENCES | RECEPTOR TYROSINE KINASE | PARKINSONS-DISEASE | Drosophila Proteins | Nerve Tissue Proteins - therapeutic use | Nerve Tissue Proteins - physiology | Neurons - chemistry | Humans | Receptor Protein-Tyrosine Kinases - physiology | Nerve Growth Factors - chemistry | Proto-Oncogene Proteins - chemistry | Nerve Growth Factors - therapeutic use | Nerve Tissue Proteins - metabolism | Nerve Tissue Proteins - chemistry | Animals | Glial Cell Line-Derived Neurotrophic Factor Receptors | Glial Cell Line-Derived Neurotrophic Factor | Neurons - physiology | Proto-Oncogene Proteins - physiology | Proto-Oncogene Proteins c-ret | Signal Transduction - physiology | Neurons - metabolism | Nerve Growth Factors - physiology | Receptor Protein-Tyrosine Kinases - chemistry
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7. Full Text The Extended Granin Family: Structure, Function, and Biomedical Implications
by Bartolomucci, Alessandro and Possenti, Roberta and Mahata, Sushil K and Fischer-Colbrie, Reiner and Loh, Y. Peng and Salton, Stephen R. J
Endocrine Reviews, ISSN 0163-769X, 12/2011, Volume 32, Issue 6, pp. 755 - 797
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II and secretogranin III), and additional related proteins (7B2, NESP55,... 
C-TERMINAL FRAGMENT | SECRETORY GRANULE BIOGENESIS | NEUROENDOCRINE POLYPEPTIDE 7B2 | PROHORMONE CONVERTASE PC2 | PLASMA CHROMOGRANIN-A | ENDOCRINOLOGY & METABOLISM | CENTRAL-NERVOUS-SYSTEM | AMYOTROPHIC-LATERAL-SCLEROSIS | VGF-DERIVED PEPTIDE | DISULFIDE-BONDED LOOP | CARDIAC NATRIURETIC PEPTIDES | Chromogranins - therapeutic use | GTP-Binding Protein alpha Subunits, Gs - chemistry | Neuroendocrine Secretory Protein 7B2 - physiology | Chromogranins - physiology | Humans | Secretory Vesicles - metabolism | Neuropeptides - physiology | Endocrine Cells - metabolism | Peptide Fragments - physiology | Neuroendocrine Cells - metabolism | Neurons - metabolism | Nerve Growth Factors - physiology | Neurons - drug effects | Neuroendocrine Secretory Protein 7B2 - chemistry | Biomarkers - metabolism | Nerve Growth Factors - chemistry | GTP-Binding Protein alpha Subunits, Gs - therapeutic use | Nerve Growth Factors - therapeutic use | Neuropeptides - therapeutic use | Sequence Homology, Amino Acid | Peptide Fragments - chemistry | Animals | Neuroendocrine Secretory Protein 7B2 - therapeutic use | Endocrine Cells - drug effects | Chromogranins - chemistry | Secretory Vesicles - drug effects | GTP-Binding Protein alpha Subunits, Gs - physiology | Peptide Fragments - therapeutic use | Neuroendocrine Cells - drug effects | Biomarkers - chemistry | Neuropeptides - chemistry | Reviews
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