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Trends in Neurosciences, ISSN 0166-2236, 2012, Volume 35, Issue 11, pp. 700 - 709
Caspase-3 has been identified as a key mediator of neuronal programmed cell death. This protease plays a central role in the developing nervous system and its... 
Neurology | synaptic plasticity | synaptic loss | Alzheimer's disease | long-term depression | neuronal differentiation | long-term potentiation | Neuronal differentiation | Synaptic loss | Long-term depression | Long-term potentiation | Synaptic plasticity | ALZHEIMERS-DISEASE | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | PROGRAMMED CELL-DEATH | MITOCHONDRIAL-MEMBRANE PERMEABILIZATION | PRECURSOR PROTEIN | HUNTINGTONS-DISEASE | PARKINSONS-DISEASE | Nerve Net - embryology | Mitochondria - enzymology | Caspase Inhibitors - pharmacology | Humans | Huntington Disease - pathology | Neurons - cytology | Nerve Net - enzymology | Molecular Targeted Therapy | Alzheimer Disease - pathology | Caspase 3 - physiology | Nervous System - growth & development | Nervous System - embryology | Huntington Disease - enzymology | Disease Models, Animal | Nerve Net - growth & development | Long-Term Synaptic Depression - physiology | Nerve Tissue Proteins - physiology | Nervous System - enzymology | Parkinson Disease - pathology | Embryonic Development - physiology | Neural Tube - physiology | Alzheimer Disease - enzymology | Receptors, N-Methyl-D-Aspartate - physiology | Mice, Knockout | Animals | Caspase Inhibitors - therapeutic use | Neurons - enzymology | Parkinson Disease - enzymology | Apoptosis Regulatory Proteins - physiology | Mice | Apoptosis - physiology | Enzyme Activation | Nervous system diseases | Neurosciences | Neural networks | Proteases | Neurons | Depression, Mental | Apoptosis | Neurodegenerative diseases | Proteinase | Central nervous system | Caspase-3 | Neurological diseases | Axons | Mitochondria | Neural tube | Plasticity (synaptic) | Reviews | Differentiation
Journal Article
Nature Reviews Neuroscience, ISSN 1471-003X, 11/2012, Volume 13, Issue 11, pp. 743 - 757
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2006, Volume 26, Issue 16, pp. 4406 - 4414
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2002, Volume 34, Issue 5, pp. 807 - 820
Extracellular signal-regulated kinases (ERK1 and 2) are synaptic signaling components necessary for several forms of learning. In mice lacking ERK1, we observe... 
MOLECULAR MECHANISMS | RECEPTOR MUTANT MICE | ACTIVATED PROTEIN-KINASE | SIGNALING PATHWAY | RAS | DOPAMINE | COCAINE | LONG-TERM POTENTIATION | EXPRESSION | NEUROSCIENCES | NUCLEUS-ACCUMBENS | Nerve Net - abnormalities | Synaptic Transmission - genetics | Male | Nerve Net - enzymology | Presynaptic Terminals - ultrastructure | Corpus Striatum - cytology | Nerve Net - cytology | Corpus Striatum - abnormalities | Amygdala - enzymology | Nucleus Accumbens - enzymology | Presynaptic Terminals - enzymology | Nervous System Malformations - enzymology | Mitogen-Activated Protein Kinase 1 - genetics | Nucleus Accumbens - cytology | Behavior, Animal - drug effects | Female | Hippocampus - enzymology | Nervous System Malformations - genetics | Corpus Striatum - enzymology | Cognition Disorders - enzymology | Nucleus Accumbens - abnormalities | Morphine - pharmacology | MAP Kinase Kinase Kinases - genetics | Nervous System Malformations - pathology | Cognition Disorders - pathology | Amygdala - cytology | Behavior, Animal - physiology | Up-Regulation - genetics | Cognition Disorders - genetics | Long-Term Potentiation - genetics | MAP Kinase Kinase Kinases - metabolism | Avoidance Learning - physiology | Hippocampus - cytology | Mutation - genetics | Mice, Knockout | Mitogen-Activated Protein Kinases - deficiency | Motor Activity - genetics | Animals | Mitogen-Activated Protein Kinases - genetics | Mice | Mitogen-Activated Protein Kinase 3 | Memory - physiology | Mitogen-Activated Protein Kinase 1 - metabolism | Proteins | Phosphorylation | Behavior | Kinases | Gene expression | Rodents
Journal Article
Trends in Neurosciences, ISSN 0166-2236, 2013, Volume 36, Issue 9, pp. 522 - 534
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 1, pp. 64 - 69
Previous studies have supported the concept that the default network is an intrinsic brain system that participates in internal modes of cognition. Neural... 
Humans | Catechol O-Methyltransferase - physiology | Male | Nerve Net - enzymology | Nerve Net - physiology | Young Adult | Methionine - physiology | Dopamine - physiology | Adolescent | Adult | Female | Prefrontal Cortex - enzymology | Prefrontal Cortex - physiology | Dopamine - metabolism | Valine - physiology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2005, Volume 25, Issue 49, pp. 11300 - 11312
Journal Article
Peptides, ISSN 0196-9781, 2010, Volume 31, Issue 8, pp. 1589 - 1597
Orexins are expressed in neurons of the dorsolateral hypothalamus and their axons widely distribute throughout the central nervous system. The noradrenergic... 
Medullary noradrenaline cell groups | Tyrosine hydroxylase | Adrenaline cell groups | Orexin | Phenylethanolamine N-methyltransferase | SLEEP | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD | AXONAL PROJECTIONS | COERULEUS-NORADRENERGIC SYSTEM | BODY-WEIGHT | NUCLEUS AMBIGUUS | ENDOCRINOLOGY & METABOLISM | CONTROLLING FOOD-INTAKE | SITES | PHARMACOLOGY & PHARMACY | MELANIN-CONCENTRATING HORMONE | HYPOTHALAMUS | Tyrosine 3-Monooxygenase - metabolism | Nerve Net - ultrastructure | Rats, Wistar | Brain Stem - ultrastructure | Nerve Fibers - enzymology | Intracellular Signaling Peptides and Proteins - metabolism | Nerve Net - enzymology | Medulla Oblongata - ultrastructure | Presynaptic Terminals - ultrastructure | Solitary Nucleus - enzymology | Brain Stem - physiology | Pons - enzymology | Brain Stem - enzymology | Locus Coeruleus - enzymology | Neurons - ultrastructure | Presynaptic Terminals - enzymology | Neurons - physiology | Phenylethanolamine N-Methyltransferase - metabolism | Solitary Nucleus - metabolism | Medulla Oblongata - physiology | Synaptophysin - metabolism | Nerve Fibers - metabolism | Orexins | Cell Communication | Rats | Neuropeptides - metabolism | Locus Coeruleus - ultrastructure | Animals | Norepinephrine - metabolism | Neurons - enzymology | Nerve Net - metabolism | Presynaptic Terminals - metabolism | Pons - ultrastructure | Solitary Nucleus - ultrastructure | Mice | Nerve Fibers - ultrastructure | Pons - metabolism | Medulla Oblongata - enzymology | Epinephrine - metabolism | Locus Coeruleus - metabolism | Tyrosine | Phenols | Hydroxylases | Peptides | Neurons | Noradrenaline | Networks | Axons | Central nervous system | Terminals | Density | Fibers
Journal Article