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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 12, pp. E1738 - E1746
The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to... 
Developmental neuroscience | Glia | RNAseq | Macrophage | Microglia | CELLS | PROGENITORS | ACTIVATION | BRAIN-INJURY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | MONOCYTES | macrophage | RECEPTOR | glia | PERIPHERAL-NERVE INJURY | developmental neuroscience | GENE-EXPRESSION | microglia | REVEALS | Macrophages - chemistry | Brain - embryology | Sciatic Nerve - injuries | Humans | Middle Aged | Nerve Tissue Proteins - analysis | Transcriptome | Gene Expression Profiling | Brain - growth & development | Endotoxemia - pathology | Membrane Proteins - analysis | Membrane Proteins - deficiency | Microglia - physiology | Gene Expression Regulation, Developmental | Cell Division | Optic Nerve Injuries - pathology | Child | Antibodies, Monoclonal - immunology | Rabbits | Brain - cytology | Lipopolysaccharides - toxicity | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Sciatic Nerve - pathology | Nerve Crush | Membrane Proteins - immunology | Organ Specificity | Temporal Lobe - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Microglia - chemistry | Cell Lineage | Animals | Sequence Analysis, RNA | Biomarkers | Aged | Mice | Physiological aspects | Neural circuitry | Proteins | Tissue | Brain | Spinal cord | Rodents | Monoclonal antibodies | Cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 04/2015, Volume 18, Issue 5, pp. 690 - 697
The developing mammalian brain is destined for a female phenotype unless exposed to gonadal hormones during a perinatal sensitive period. It has been assumed... 
SPINE PLASTICITY | SEXUAL-DIFFERENTIATION | BEHAVIOR | MAST-CELLS | ESTRADIOL | ESTROGEN | RAT-BRAIN | EXPRESSION | NEUROSCIENCES | PROSTAGLANDIN-E2 | FEMALE | DNA (Cytosine-5-)-Methyltransferases - physiology | Nerve Tissue Proteins - deficiency | Nerve Tissue Proteins - analysis | Testosterone - physiology | Cytidine - pharmacology | Male | Copulation - drug effects | Brain - growth & development | Cytidine - analogs & derivatives | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Preoptic Area - physiopathology | Testosterone - pharmacology | Phthalimides - pharmacology | DNA Methylation | Gene Expression Regulation, Developmental | Tryptophan - analogs & derivatives | Nerve Tissue Proteins - biosynthesis | Female | Disorders of Sex Development - physiopathology | Estradiol - physiology | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Tissue Proteins - physiology | DNA (Cytosine-5-)-Methyltransferases - deficiency | Microfilament Proteins - analysis | Rats | Sex Characteristics | DNA, Intergenic - genetics | Disorders of Sex Development - genetics | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | DNA (Cytosine-5-)-Methyltransferases - genetics | Sex Differentiation - physiology | Copulation - physiology | Animals | Protein Isoforms - biosynthesis | CpG Islands | Mice | Tryptophan - pharmacology | Preoptic Area - enzymology | Protein Isoforms - genetics | Enzymes | Hormones, Sex | Regulation | Gene expression | Properties | Health aspects | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 06/2013, Volume 78, Issue 6, pp. 971 - 985
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2006, Volume 172, Issue 1, pp. 41 - 53
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2014, Volume 41, Issue 1, pp. 90 - 100
Abstract Depression is an inflammatory disorder. Pro-inflammatory cytokine interleukin-1 beta (IL-1β) may play a pivotal role in the central nervous system... 
Psychiatry | Allergy and Immunology | Depression | IL-1β-related CNS inflammation | Chronic unpredictable mild stress | Prefrontal cortex | NLRP3 inflammasome | ANTIDEPRESSANT | CHRONIC MILD STRESS | CYTOKINE LEVELS | MAJOR DEPRESSION | IMMUNOLOGY | IL-1 beta-related CNS inflammation | FLUOXETINE | NEUROSCIENCES | TOLL-LIKE | DISORDER | ALTERED EXPRESSION | PITUITARY-ADRENAL AXIS | BRAIN | Microglia - metabolism | Rats, Wistar | Sucrose | Depressive Disorder - pathology | NLR Family, Pyrin Domain-Containing 3 Protein | Nerve Tissue Proteins - analysis | Stress, Physiological | Depressive Disorder - drug therapy | Male | NF-kappa B - metabolism | Receptors, Cytoplasmic and Nuclear - biosynthesis | Interleukin-1beta - blood | Prefrontal Cortex - pathology | Nerve Tissue Proteins - biosynthesis | Microglia - pathology | Interleukin-1beta - biosynthesis | Fluoxetine - therapeutic use | Carrier Proteins | Interleukin-1beta - physiology | Nerve Tissue Proteins - physiology | Calcium-Binding Proteins - analysis | Gene Expression Regulation | Interleukin-1beta - cerebrospinal fluid | Microfilament Proteins - analysis | Rats | Anhedonia | Receptors, Cytoplasmic and Nuclear - physiology | Inflammation | Random Allocation | Depressive Disorder - metabolism | Drinking Behavior | Antidepressive Agents - therapeutic use | Inflammasomes - physiology | Animals | Receptors, Cytoplasmic and Nuclear - analysis | Prefrontal Cortex - metabolism | Enzyme Activation | Chronic Disease | Index Medicus
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2008, Volume 31, Issue 4, pp. 578 - 590
Abstract Astrocyte pathology occurs in association with Alzheimer's disease (AD) and in brain ageing, but is poorly characterised. We sought to define the... 
Neurology | Internal Medicine | Aging | Alzheimer's type pathology | Excitatory amino acid transporter | Temporal cortex | Astrocyte | Glial fibrillary acidic protein | OXIDATIVE STRESS | AMYLOID PLAQUES | FIBROUS ASTROCYTES | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | COGNITIVE FUNCTION | GERIATRICS & GERONTOLOGY | IN-VITRO | CEREBROSPINAL-FLUID S100B | SENILE-DEMENTIA | FIBRILLARY ACIDIC PROTEIN | GLUTAMATE TRANSPORTER | Immunohistochemistry | Predictive Value of Tests | Prospective Studies | Humans | Astrocytes - pathology | Nerve Tissue Proteins - analysis | tau Proteins - metabolism | Male | Gliosis - physiopathology | Nerve Growth Factors - metabolism | Glial Fibrillary Acidic Protein - metabolism | Alzheimer Disease - pathology | Brain - metabolism | Gliosis - pathology | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Female | Biomarkers - metabolism | Severity of Illness Index | Alzheimer Disease - physiopathology | Plaque, Amyloid - pathology | S100 Calcium Binding Protein beta Subunit | Brain - physiopathology | Glial Fibrillary Acidic Protein - analysis | Gliosis - metabolism | Biomarkers - analysis | S100 Proteins - metabolism | Excitatory Amino Acid Transporter 1 - metabolism | Excitatory Amino Acid Transporter 2 - analysis | Excitatory Amino Acid Transporter 2 - metabolism | S100 Proteins - analysis | Nerve Growth Factors - analysis | Nerve Tissue Proteins - metabolism | Phenotype | Alzheimer Disease - metabolism | Amyloid beta-Peptides - analysis | Brain - pathology | Plaque, Amyloid - metabolism | Aged | tau Proteins - analysis | Excitatory Amino Acid Transporter 1 - analysis | Longitudinal Studies | Astrocytes - metabolism | Cohort Studies | Amino acids | Genetic aspects | Alzheimer's disease | Intermediate filament proteins | Public health | Index Medicus
Journal Article
Journal of Periodontal Research, ISSN 0022-3484, 08/2015, Volume 50, Issue 4, pp. 461 - 467
Background and ObjectiveThe main purpose of this study was to isolate and characterize gingival connective tissue-derived mesenchymal stem cells (GMSCs). The... 
multipotent stem cells | stem cells | gingiva | mesenchymal stromal cells | Mesenchymal stromal cells | Gingiva | Multipotent stem cells | Stem cells | DISPASE | COLLAGENASE | REGENERATION | PERIODONTAL-LIGAMENT | DENTAL-PULP | HUMAN ADIPOSE-TISSUE | IN-VITRO | HUMAN BONE-MARROW | DENTISTRY, ORAL SURGERY & MEDICINE | EXPANSION | CULTURES | Cell Adhesion Molecules, Neuronal - analysis | Collagenases - administration & dosage | Osteogenesis - physiology | Humans | Nerve Tissue Proteins - analysis | Receptors, Nerve Growth Factor - analysis | Cell Aggregation - physiology | Adipogenesis - physiology | Antigens, CD - analysis | Fetal Proteins - analysis | Mesenchymal Stromal Cells - cytology | Time Factors | Cell Shape | Cell Differentiation - physiology | CD146 Antigen - analysis | GPI-Linked Proteins - analysis | 5'-Nucleotidase - analysis | Stage-Specific Embryonic Antigens - analysis | Cell Separation - methods | Cytoskeleton - ultrastructure | Endopeptidases - administration & dosage | Endoglin - analysis | Hyaluronan Receptors - analysis | Vimentin - analysis | Chondrogenesis - physiology | Cell Adhesion - physiology | Multipotent Stem Cells - cytology | Gingiva - cytology | Fibroblasts - cytology | Thy-1 Antigens - analysis | Antigens, Surface - analysis | Connective Tissue Cells - cytology | Intermediate filament proteins | Index Medicus | Dentistry
Journal Article