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PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 11, p. e1003773
... with the mitochondrial adaptor protein MAVS (also known as IPS-1, CARDIF and VISA) and initiates a signalling cascade that culminates in the activation of the transcriptional... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Immunologic research, ISSN 1559-0755, 2011, Volume 51, Issue 1, pp. 45 - 60
... and transcription factors and inhibiting apoptosis. This induction by C5b-9 is dependent upon the activation of the phosphatidylinositol 3-kinase/Akt/FOXO1 and ERK1 pathways in a Gi protein-dependent manner... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 3, p. e57208
... disruption of tissue (primary injury), as well as through delayed and potentially reversible molecular and cellular pathophysiological mechanisms, which cause... 
SYSTEM | ACTIVATION | INHIBITION | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE RECEPTORS | SPINAL-CORD-INJURY | RELEASE | NITRIC-OXIDE-SYNTHASE | NF-KAPPA-B | EXPRESSION | NEUROPROTECTION | Nitric Oxide Synthase Type II - biosynthesis | I-kappa B Proteins - immunology | Cerebral Cortex - pathology | MAP Kinase Kinase 4 - immunology | NF-kappa B - metabolism | Brain Injuries - metabolism | Interleukin-1beta - genetics | Tyrosine - analogs & derivatives | Inflammation - metabolism | Tryptases - immunology | NF-KappaB Inhibitor alpha | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Brain Injuries - genetics | Poly(ADP-ribose) Polymerases - biosynthesis | Tyrosine - immunology | Mice, Knockout | Tyrosine - metabolism | Cerebral Cortex - immunology | Tryptases - biosynthesis | MAP Kinase Kinase 4 - genetics | Mice | Poly (ADP-Ribose) Polymerase-1 | Poly(ADP-ribose) Polymerases - immunology | Toll-Like Receptor 4 - biosynthesis | NF-kappa B - immunology | Brain Infarction - metabolism | Brain Infarction - pathology | I-kappa B Proteins - metabolism | I-kappa B Proteins - genetics | Cerebral Cortex - metabolism | Glial Fibrillary Acidic Protein | MAP Kinase Kinase 4 - metabolism | Brain Injuries - immunology | Nitric Oxide Synthase Type II - immunology | Nerve Tissue Proteins - biosynthesis | Interleukin-1beta - biosynthesis | Tryptases - genetics | Nerve Tissue Proteins - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Interleukin-1beta - immunology | Inflammation - immunology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Brain Infarction - immunology | Inflammation - genetics | Brain Infarction - genetics | Brain Injuries - pathology | Tyrosine - genetics | Brain | Brain damage | Brain research | Neurons | Injuries | Neuroprotection | Animal models | Traumatic brain injury | Bax protein | Bcl-2 protein | Control methods | Kinases | Proteins | Signal transduction | Receptors | Head injuries | Animal tissues | Toll-like receptors | Immune system | Translocation | NF-κB protein | Glial fibrillary acidic protein | Cortex | Poly(ADP-ribose) polymerase | JNK protein | Inflammation | TLR4 protein | IL-1β | Trauma | Nitric-oxide synthase | Chymase | Augmentation | Signaling | Injury prevention | Tryptase | Nitrotyrosine | Apoptosis
Journal Article
PloS one, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e48854
...) in the host involves the migration of immature dendritic cells (iDCs). iDCs migrate in response to the HIV-1 envelope protein, gp120, and inhibiting such migration may limit the mucosal transmission of HIV-1... 
SLIT | PROTEIN | REPELLENT | HIV | ANGIOGENESIS | CHEMOTAXIS | MULTIDISCIPLINARY SCIENCES | GUIDANCE | RECEPTORS | ROBO | MIDLINE | Paxillin - metabolism | Proto-Oncogene Proteins pp60(c-src) - immunology | Pseudopodia - immunology | Human Umbilical Vein Endothelial Cells - metabolism | Dendritic Cells - immunology | Humans | Actins - metabolism | Human Umbilical Vein Endothelial Cells - immunology | cdc42 GTP-Binding Protein - metabolism | Paxillin - immunology | Actins - immunology | HIV Envelope Protein gp120 - metabolism | Cell Movement - immunology | HIV Envelope Protein gp120 - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Signal Transduction - immunology | rac1 GTP-Binding Protein - immunology | Actin-Related Protein 2-3 Complex - metabolism | Focal Adhesion Kinase 2 - metabolism | RNA Interference | cdc42 GTP-Binding Protein - immunology | Wiskott-Aldrich Syndrome Protein - metabolism | Microfilament Proteins - metabolism | Receptors, Immunologic - immunology | Microfilament Proteins - genetics | Dendritic Cells - metabolism | Nerve Tissue Proteins - immunology | Cells, Cultured | Protein Binding - immunology | Blotting, Western | Actin-Related Protein 2-3 Complex - immunology | Nerve Tissue Proteins - metabolism | Microscopy, Confocal | Wiskott-Aldrich Syndrome Protein - immunology | Proto-Oncogene Proteins pp60(c-src) - metabolism | Microfilament Proteins - immunology | Intercellular Signaling Peptides and Proteins - immunology | Receptors, Immunologic - metabolism | rac1 GTP-Binding Protein - metabolism | Focal Adhesion Kinase 2 - immunology | Dendritic cells | HIV (Viruses) | Muscle proteins | Actin | Protein binding | Cdc42 protein | Sexually transmitted diseases--STD | Motility | Leukocyte migration | Mucosa | Viruses | Smooth muscle | Kinases | Tissues | Medical schools | Cell adhesion & migration | Proteins | Angiogenesis | Human immunodeficiency virus--HIV | Inhibition | Sequestering | Localization | Wiskott-Aldrich syndrome | LSP1 protein | Envelope protein | Rac1 protein | Glycoproteins | White blood cells | Medicine | Actin-related protein 2 | Signaling | Disease transmission | Ligands | Paxillin | Glycoprotein gp120 | Cell migration | STD | Sexually transmitted diseases | Human immunodeficiency virus
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2017, Volume 18, Issue 6, pp. 665 - 674
Journal Article
Nature (London), ISSN 1476-4687, 2003, Volume 425, Issue 6961, pp. 973 - 977
Journal Article
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2005, Volume 22, Issue 5, pp. 551 - 560
Outer membrane protein A (OmpA) is a conserved major component of the outer membrane of Enterobacteriaceae... 
C-REACTIVE PROTEIN | AMYLOID-P COMPONENT | DENDRITIC CELLS | MACROPHAGES | INFLAMMATION | ACUTE PHASE PROTEINS | TOLL-LIKE RECEPTORS | SCAVENGER RECEPTORS | DIFFERENTIATION | IMMUNOLOGY | LONG PENTRAXIN PTX3 | Toll-Like Receptor 2 | Dendritic Cells - immunology | Humans | Nerve Tissue Proteins - deficiency | Scavenger Receptors, Class F | Scavenger Receptors, Class E | C-Reactive Protein - metabolism | Transfection | C-Reactive Protein - deficiency | Receptors, Immunologic - immunology | CHO Cells | Recombinant Proteins - metabolism | Receptors, LDL - genetics | Cricetinae | Bacterial Outer Membrane Proteins - immunology | Klebsiella pneumoniae - immunology | Nerve Tissue Proteins - immunology | Signal Transduction | Receptors, Oxidized LDL | Mice, Inbred C57BL | Receptors, Immunologic - deficiency | Receptors, LDL - metabolism | C-Reactive Protein - genetics | Recombinant Proteins - genetics | Receptors, LDL - immunology | Immunity, Innate | Nerve Tissue Proteins - genetics | Macrophage Activation | Mice, Knockout | Nerve Tissue Proteins - metabolism | Models, Immunological | Animals | Receptors, Scavenger | Recombinant Proteins - immunology | Mice | In Vitro Techniques | Receptors, Immunologic - genetics | Immunity, Cellular | C-Reactive Protein - immunology | Receptors, Immunologic - metabolism | Medical colleges | Drug resistance in microorganisms | Pneumonia | Dendritic cells | Bacterial pneumonia | Antitank weapons | Proteins | Microorganisms | Statistical analysis | Bacteria | Ligands | Gram-negative bacteria | Immune system
Journal Article