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2012, ISBN 9780791860038, viii, 99
Book
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 1, pp. 126 - 134
Purpose To perform a comprehensive cognitive function (CF) assessment in patients who were relapse free after curative intent radiotherapy (RT) or... 
Radiology | Hematology, Oncology and Palliative Medicine | Squamous cell carcinoma of the head and neck | Chemotherapy | Neuropsychological testing | Radiotherapy | Cognitive dysfunction | PROPHYLACTIC CRANIAL IRRADIATION | ADJUVANT CHEMOTHERAPY | DRIVING PERFORMANCE | FOLLOW-UP | CELL LUNG-CANCER | BREAST-CANCER | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | NEUROCOGNITIVE FUNCTION | LOW-GRADE GLIOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Pharyngeal Neoplasms - radiotherapy | Cerebellum - radiation effects | Prospective Studies | Humans | Middle Aged | Male | Pharyngeal Neoplasms - drug therapy | Antineoplastic Agents - administration & dosage | Cognition - physiology | Laryngeal Neoplasms - drug therapy | Neoplasms, Squamous Cell - pathology | Carcinoma - drug therapy | Carcinoma - blood | Affect - physiology | Head and Neck Neoplasms - drug therapy | Cognition - drug effects | Neoplasms, Squamous Cell - blood | Head and Neck Neoplasms - pathology | Carcinoma, Squamous Cell | Neuropsychological Tests | Cognition Disorders - diagnosis | Memory Disorders - etiology | Hypopharyngeal Neoplasms - pathology | Quality of Life | Pharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - drug therapy | Temporal Lobe - drug effects | Laryngeal Neoplasms - blood | Cerebellum - drug effects | Hypopharyngeal Neoplasms - blood | Cisplatin - administration & dosage | Feasibility Studies | Laryngeal Neoplasms - pathology | Squamous Cell Carcinoma of Head and Neck | Head and Neck Neoplasms - blood | Antineoplastic Agents - adverse effects | Cognition Disorders - etiology | Neoplasms, Squamous Cell - drug therapy | Neoplasms, Squamous Cell - radiotherapy | Female | Carcinoma - pathology | Cognition - radiation effects | Affect - drug effects | Pharyngeal Neoplasms - blood | Affect - radiation effects | Carcinoma - radiotherapy | Combined Modality Therapy - adverse effects | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Cisplatin - adverse effects | Aged | Combined Modality Therapy - methods | Temporal Lobe - radiation effects | Care and treatment | Squamous cell carcinoma | Cancer | BODY FLUIDS | HEAD | NERVOUS SYSTEM | RADIATION DOSES | MEDICINE | THERAPY | CEREBELLUM | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | COMBINED THERAPY | BRAIN | RADIOLOGY | BLOOD | NEOPLASMS | BIOLOGICAL MATERIALS | CENTRAL NERVOUS SYSTEM | STANDARD OF LIVING | CHEMOTHERAPY | NUCLEAR MEDICINE | ORGANS | DISEASES | DOSES | CARCINOMAS | NECK | DOSIMETRY | BODY | MATERIALS
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2018, Volume 35, Issue 9, pp. 1 - 20
The treatment of metastatic lesions in the brain represents a serious unmet medical need in the field of neuro-oncology. Even though many effective compounds... 
Biochemistry, general | Biomedical Engineering | blood-brain barrier | Biomedicine | metastasize | Pharmacy | brain metastases | Medical Law | efflux transporters | molecularly-targeted anti-cancer agents | drug delivery | Pharmacology/Toxicology | PROPHYLACTIC CRANIAL IRRADIATION | RESISTANCE PROTEIN ABCG2 | MULTICENTER PHASE-II | EML4-ALK FUSION GENE | CHEMISTRY, MULTIDISCIPLINARY | P-GLYCOPROTEIN ABCB1 | NEGATIVE BREAST-CANCER | CELL LUNG-CANCER | MOLECULARLY TARGETED THERAPIES | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | CEREBROSPINAL-FLUID CONCENTRATION | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Brain Neoplasms - pathology | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - metabolism | Antineoplastic Agents - administration & dosage | Brain Neoplasms - metabolism | Breast Neoplasms - metabolism | Brain - metabolism | Brain Neoplasms - secondary | Female | Antineoplastic Agents - pharmacokinetics | Carcinoma, Renal Cell - drug therapy | Molecular Targeted Therapy - methods | Melanoma - metabolism | Carcinoma, Renal Cell - pathology | Melanoma - pathology | Brain Neoplasms - drug therapy | Blood-Brain Barrier - drug effects | Breast Neoplasms - drug therapy | Blood-Brain Barrier - metabolism | Brain - drug effects | Blood-Brain Barrier - pathology | Carcinoma, Renal Cell - metabolism | Animals | Breast Neoplasms - pathology | Melanoma - drug therapy | Brain - pathology | Kidney Neoplasms - pathology | Kidney Neoplasms - drug therapy | Drug Delivery Systems - methods | Precision Medicine - methods | Drugs | Care and treatment | Drug delivery systems | Therapeutics | Brain damage | Metastasis | Permeability | Homeopathy | Materia medica and therapeutics | Vehicles | Efflux | Brain | Toxicity | Brain tumors | Central nervous system | Membrane permeability | Oncology | Success | Metastases | Medicine | Blood-brain barrier | Precision medicine | Lesions | Tumors
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 77, Issue 3, pp. 655 - 661
Purpose Controversy endures regarding the optimal treatment of patients with brain metastases (BMs). Debate persists, despite many randomized trials, perhaps... 
Radiology | Hematology, Oncology and Palliative Medicine | radiotherapy | Brain metastases | prognosis | stereotactic radiosurgery | COST-EFFECTIVENESS | PARTITIONING ANALYSIS RPA | RADIATION-THERAPY | TRIAL | ONCOLOGY | NEUROCOGNITIVE FUNCTION | RANDOMIZED PHASE-III | ACCELERATED-FRACTIONATION | SINGLE METASTASES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Carcinoma, Non-Small-Cell Lung - radiotherapy | Gastrointestinal Neoplasms | Prognosis | Age Factors | Humans | Middle Aged | Lung Neoplasms | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - secondary | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Karnofsky Performance Status | Small Cell Lung Carcinoma - radiotherapy | Retrospective Studies | Brain Neoplasms - radiotherapy | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms | Brain Neoplasms - diagnosis | Melanoma - radiotherapy | Treatment Outcome | Brain Neoplasms - drug therapy | Melanoma - secondary | Carcinoma, Renal Cell - radiotherapy | Analysis of Variance | Carcinoma, Renal Cell - secondary | Melanoma - drug therapy | Skin Neoplasms | Selection Bias | Aged | Combined Modality Therapy - methods | Carcinoma, Non-Small-Cell Lung - drug therapy | Care and treatment | Metastasis | Patient outcomes | Analysis | SURGERY | METASTASES | NERVOUS SYSTEM | CENTRAL NERVOUS SYSTEM | MEDICINE | NUCLEAR MEDICINE | ORGANS | THERAPY | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | BODY | BRAIN | RADIOLOGY
Journal Article
2007, 2006. 3rd. Corrected, M.D. Anderson cancer care series, ISBN 0387292020, xii, 364
"Tumors of the Brain and Spine" focuses primarily on the standard approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors... 
Brain | Treatment | Spine | Tumors | Clinical & internal medicine | Neurology | Pathology | Oncology | Neurosurgery | Medicine & Public Health | Surgical Oncology
Book
Neurology, ISSN 0028-3878, 09/2004, Volume 63, Issue 5, pp. 901 - 903
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 9, pp. 829 - 838
Alectinib, a potent ALK tyrosine kinase inhibitor, was more effective and somewhat less toxic than crizotinib when used as primary therapy in patients with ALK... 
RESISTANT | MEDICINE, GENERAL & INTERNAL | MODELS | ANTITUMOR-ACTIVITY | INHIBITOR ALECTINIB | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Follow-Up Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Central Nervous System Neoplasms - secondary | Young Adult | Pyridines - adverse effects | Anaplastic Lymphoma Kinase | Antineoplastic Agents - adverse effects | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Receptor Protein-Tyrosine Kinases - analysis | Pyrazoles - adverse effects | Pyridines - therapeutic use | Crizotinib | Carbazoles - adverse effects | Kaplan-Meier Estimate | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Animals | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Piperidines - adverse effects | Intention to Treat Analysis | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Central Nervous System Neoplasms - drug therapy | Drugs | Care and treatment | Analysis | Comparative analysis | Lung cancer, Non-small cell | Health aspects | Systemic diseases | Toxicity | Lung cancer | Central nervous system | Non-small cell lung carcinoma | Oncology | Nervous system | Metastasis | Radiation therapy | Patients | Lymphoma | Cancer therapies | Survival | Mutation | Protein-tyrosine kinase | Drug dosages | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2008, Volume 26, Issue 15, pp. 2512 - 2518
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 86, Issue 1, pp. 114 - 120
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 7/2006, Volume 78, Issue 3, pp. 255 - 260
Treatment options for patients with recurrent central nervous system (CNS) metastases are limited. Rapid infusion of high-dose intravenous methotrexate (HD IV... 
metastases | Medicine & Public Health | leptomeninges | Oncology | methotrexate | brain | chemotherapy | central nervous system | Brain | Chemotherapy | Methotrexate | Central nervous system | Leptomeninges | Metastases | SOLID TUMORS | PHASE-II | CANCER | CLINICAL NEUROLOGY | TEMOZOLOMIDE | TRIAL | CAPECITABINE | ONCOLOGY | LEPTOMENINGEAL METASTASES | RECURRENT | BRAIN METASTASES | NEOPLASTIC MENINGITIS | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antimetabolites, Antineoplastic - administration & dosage | Central Nervous System Neoplasms - secondary | Dose-Response Relationship, Drug | Carcinoma, Squamous Cell - mortality | Adult | Female | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Neoplasms, Unknown Primary - drug therapy | Head and Neck Neoplasms - drug therapy | Treatment Outcome | Neoplasms, Unknown Primary - mortality | Breast Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - mortality | Head and Neck Neoplasms - pathology | Methotrexate - adverse effects | Carcinoma, Squamous Cell - drug therapy | Breast Neoplasms - pathology | Antimetabolites, Antineoplastic - adverse effects | Survival Analysis | Breast Neoplasms - mortality | Methotrexate - administration & dosage | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Head and Neck Neoplasms - mortality | Infusions, Intravenous | Central Nervous System Neoplasms - drug therapy | Central Nervous System Neoplasms - mortality | Neoplasms, Unknown Primary - pathology | Metastasis
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 78 - 81
Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the haematopoietic stem cell (HSC) compartment. Most MPN patients have a common... 
TYROSINE KINASE JAK2 | JAK2-V617F | ACTIVATING MUTATION | POLYCYTHEMIA-VERA | BONE | MULTIDISCIPLINARY SCIENCES | Neuroprotective Agents - therapeutic use | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Sympathetic Nervous System - drug effects | Humans | Hematopoietic Stem Cells - pathology | Myeloproliferative Disorders - pathology | Sympathetic Nervous System - physiopathology | Adrenergic beta-3 Receptor Agonists - pharmacology | Neuroprotective Agents - pharmacology | Interleukin-1beta - metabolism | Neoplastic Stem Cells - pathology | Female | Sympathetic Nervous System - pathology | Schwann Cells - drug effects | Hematopoietic Stem Cells - drug effects | Nerve Fibers - pathology | Mesenchymal Stromal Cells - drug effects | Stem Cell Niche | Janus Kinase 2 - genetics | Nerve Fibers - drug effects | Schwann Cells - pathology | Myeloproliferative Disorders - drug therapy | Receptors, Adrenergic, beta-3 - metabolism | Disease Progression | Neoplasms - drug therapy | Nestin - metabolism | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Mice | Mesenchymal Stromal Cells - pathology | Neoplasms - pathology | Complications and side effects | Development and progression | Health aspects | Peripheral nerve diseases | Hematopoietic stem cells | Myeloproliferative disorders | Tumors | Studies | Mutation | Kinases | Rodents | Stem cells | Apoptosis
Journal Article