2016, Textes littéraires français, ISBN 2600018700, Volume 636., ccxlviii, 270
Book
1998, ISBN 9783791319339, 232
Book
Neurobiology of Aging, ISSN 0197-4580, 01/2015, Volume 36, Issue 1, pp. 134 - 148
The entorhinal cortex (EC) is one of the first brain areas to display neuropathology in Alzheimer's disease. A mouse model which simulates amyloid-β (Aβ)...
Excitability | Retrosplenial cortex | Prefrontal cortex | NeuN | Entorhinal cortex | Object placement
Excitability | Retrosplenial cortex | Prefrontal cortex | NeuN | Entorhinal cortex | Object placement
Journal Article
Cell Stem Cell, ISSN 1934-5909, 04/2018, Volume 22, Issue 4, pp. 589 - 599.e5
Adult hippocampal neurogenesis declines in aging rodents and primates. Aging humans are thought to exhibit waning neurogenesis and exercise-induced...
volume | Sox2 | Ki-67 | dentate gyrus | doublecortin | NeuN | granule cells | nestin | neural progenitor | PSA-NCAM | PATTERN SEPARATION | STEM-CELLS | HUMAN BRAIN | ALZHEIMERS-DISEASE | ADULT DENTATE GYRUS | NEURONS | OLD-AGE | NEURAL PROGENITOR CELLS | MAJOR DEPRESSION | CHRONIC STRESS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Dentate Gyrus - metabolism | Humans | Middle Aged | Neurons - cytology | Hippocampus - cytology | Neurogenesis | Young Adult | Hippocampus - metabolism | Dentate Gyrus - cytology | Adolescent | Aging | Adult | Aged | Neurons - metabolism
volume | Sox2 | Ki-67 | dentate gyrus | doublecortin | NeuN | granule cells | nestin | neural progenitor | PSA-NCAM | PATTERN SEPARATION | STEM-CELLS | HUMAN BRAIN | ALZHEIMERS-DISEASE | ADULT DENTATE GYRUS | NEURONS | OLD-AGE | NEURAL PROGENITOR CELLS | MAJOR DEPRESSION | CHRONIC STRESS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Dentate Gyrus - metabolism | Humans | Middle Aged | Neurons - cytology | Hippocampus - cytology | Neurogenesis | Young Adult | Hippocampus - metabolism | Dentate Gyrus - cytology | Adolescent | Aging | Adult | Aged | Neurons - metabolism
Journal Article
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, ISSN 1596-5996, 08/2019, Volume 18, Issue 8, pp. 1739 - 1743
Purpose: To investigate the protective effect of Epimedium brevicornu Maxim extract (EBME) against Alzheimer's disease in 3xTg-AD mice. Methods: The cognitive...
Memory impairment | NeuN-positive cells | NEUN | Amyloid beta deposits | PHARMACOLOGY & PHARMACY | Epimedium brevicornu | Alzheimer's disease | EXPRESSION
Memory impairment | NeuN-positive cells | NEUN | Amyloid beta deposits | PHARMACOLOGY & PHARMACY | Epimedium brevicornu | Alzheimer's disease | EXPRESSION
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 03/2019, Volume 527, Issue 4, pp. 767 - 779
Neuronal death and replacement, or neuronal turnover, in the adult brain are one of many fundamental processes of neural plasticity. The adult avian song...
seasonal plasticity | adult neurogenesis | steroid hormone | testosterone | neuronal death | anti‐BrdU (RRID: AB_2536432) | songbird | anti‐NeuN (RRID: AB_2532109) | degeneration | anti-BrdU (RRID: AB_2536432) | anti-NeuN (RRID: AB_2532109) | MOTOR PATHWAY | NEUROTROPHIC FACTOR | PROLIFERATION | NEUROSCIENCES | ZEBRA FINCH | ZOOLOGY | CONTROL-SYSTEM | CANARY | SONG CONTROL NUCLEUS | NEUROGENESIS | BRAIN | PLASTICITY | Seasonal variations | Song | Cell survival | Neurons | Forebrain | Death | Breeding seasons | Song control nuclei | Steroid hormones | Plasticity (neural)
seasonal plasticity | adult neurogenesis | steroid hormone | testosterone | neuronal death | anti‐BrdU (RRID: AB_2536432) | songbird | anti‐NeuN (RRID: AB_2532109) | degeneration | anti-BrdU (RRID: AB_2536432) | anti-NeuN (RRID: AB_2532109) | MOTOR PATHWAY | NEUROTROPHIC FACTOR | PROLIFERATION | NEUROSCIENCES | ZEBRA FINCH | ZOOLOGY | CONTROL-SYSTEM | CANARY | SONG CONTROL NUCLEUS | NEUROGENESIS | BRAIN | PLASTICITY | Seasonal variations | Song | Cell survival | Neurons | Forebrain | Death | Breeding seasons | Song control nuclei | Steroid hormones | Plasticity (neural)
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 05/2015, Volume 132, pp. 96 - 102
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 4/2016, Volume 53, Issue 3, pp. 1637 - 1647
Neuronal nuclei (NeuN) is a well-recognized “marker” that is detected exclusively in post-mitotic neurons and was initially identified through an immunological...
Neurology | Neurosciences | Splicing regulator | Biomedicine | NeuN | Rbfox3 | Neurobiology | Neuronal marker | Mature neurons | Cell Biology | CELL-TYPE | IMMUNOREACTIVITY | NUCLEAR ANTIGEN NEUN | HUMAN-TISSUES | DOPAMINERGIC-NEURONS | NEUROSCIENCES | PRE-MESSENGER-RNA | CULTURED HUMAN | PROTEIN EXPRESSION | MAP-2 | BRAIN | Nerve Tissue Proteins - physiology | Alternative Splicing | Neurons - chemistry | Humans | Cells, Cultured | Gene Expression Regulation | Stress, Physiological | Antigens, Nuclear - physiology | Cytoplasm - metabolism | Neurodevelopmental Disorders - genetics | Epitopes | Nervous System Diseases - genetics | Axotomy | Animals | Cell Nucleus - metabolism | RNA Splicing Factors - physiology | Neurodevelopmental Disorders - metabolism | Biomarkers | Nervous System Diseases - metabolism | Vertebrates - metabolism | Neurons | Protein expression
Neurology | Neurosciences | Splicing regulator | Biomedicine | NeuN | Rbfox3 | Neurobiology | Neuronal marker | Mature neurons | Cell Biology | CELL-TYPE | IMMUNOREACTIVITY | NUCLEAR ANTIGEN NEUN | HUMAN-TISSUES | DOPAMINERGIC-NEURONS | NEUROSCIENCES | PRE-MESSENGER-RNA | CULTURED HUMAN | PROTEIN EXPRESSION | MAP-2 | BRAIN | Nerve Tissue Proteins - physiology | Alternative Splicing | Neurons - chemistry | Humans | Cells, Cultured | Gene Expression Regulation | Stress, Physiological | Antigens, Nuclear - physiology | Cytoplasm - metabolism | Neurodevelopmental Disorders - genetics | Epitopes | Nervous System Diseases - genetics | Axotomy | Animals | Cell Nucleus - metabolism | RNA Splicing Factors - physiology | Neurodevelopmental Disorders - metabolism | Biomarkers | Nervous System Diseases - metabolism | Vertebrates - metabolism | Neurons | Protein expression
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 04/2009, Volume 513, Issue 5, pp. 532 - 541
The human brain is often considered to be the most cognitively capable among mammalian brains and to be much larger than expected for a mammal of our body...
comparative neuroanatomy | glia/neuron ratio | neuron numbers | evolution | human | brain size | Human | Neuron numbers | Comparative neuroanatomy | Evolution | Glia/neuron ratio | Brain size | NERVOUS-SYSTEM | NUCLEAR ANTIGEN NEUN | FRONTAL-CORTEX | SIZE | ANTHROPOID PRIMATES | NEUROSCIENCES | PREFRONTAL CORTEX | TEMPORAL-LOBE | DENSITY | CELLULAR SCALING RULES | ZOOLOGY | GLIA | Immunohistochemistry | Brain - cytology | Antigens, Nuclear - metabolism | Humans | Middle Aged | Male | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Brain - metabolism | Nerve Tissue Proteins - metabolism | Neuroglia - metabolism | Aged | Neurons - metabolism
comparative neuroanatomy | glia/neuron ratio | neuron numbers | evolution | human | brain size | Human | Neuron numbers | Comparative neuroanatomy | Evolution | Glia/neuron ratio | Brain size | NERVOUS-SYSTEM | NUCLEAR ANTIGEN NEUN | FRONTAL-CORTEX | SIZE | ANTHROPOID PRIMATES | NEUROSCIENCES | PREFRONTAL CORTEX | TEMPORAL-LOBE | DENSITY | CELLULAR SCALING RULES | ZOOLOGY | GLIA | Immunohistochemistry | Brain - cytology | Antigens, Nuclear - metabolism | Humans | Middle Aged | Male | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Brain - metabolism | Nerve Tissue Proteins - metabolism | Neuroglia - metabolism | Aged | Neurons - metabolism
Journal Article
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, ISSN 1596-5996, 09/2019, Volume 18, Issue 9, pp. 1903 - 1907
Purpose: To investigate the protective effect of Acorus tatarinowii extract (ATE) against Alzheimer's disease in 3xTg-AD mice. Method: The cognitive function...
NeuN-positive cells | Neurodegenerative diseases | Amyloid beta deposits | MODEL | Memory impairment | Acorus tatarinowii | NEUN | DISEASE | A-BETA | PHARMACOLOGY & PHARMACY | RAT HIPPOCAMPUS | Alzheimer's disease | EXPRESSION
NeuN-positive cells | Neurodegenerative diseases | Amyloid beta deposits | MODEL | Memory impairment | Acorus tatarinowii | NEUN | DISEASE | A-BETA | PHARMACOLOGY & PHARMACY | RAT HIPPOCAMPUS | Alzheimer's disease | EXPRESSION
Journal Article
1991, ISBN 9783926023315, 173
Book
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2171 - 2192
SNCA/α-synuclein aggregation plays a crucial role in synucleinopathies such as Parkinson disease and dementia with Lewy bodies. Aggregating and nonaggregating...
GFAP, glial fibrillary acidic protein | HSPA8/Hsc70, heat shock 70kDa protein 8 | lysosomal degradation | BafA1, bafilomycinA | CASP3/aCasp3, caspase-3 | ESCRT, endosomal sorting complex required for transport | PF, particle fraction | ANXA5, annexin A5 | SNCA-T, tagged α-synuclein | PDGFB/PDGFb, platelet-derived growth factor subunit b | PD, Parkinson disease | S100B/S100b, S100 calcium-binding protein B | HRP, horseradish peroxidase | TUBB3/b-III-Tub, tubulin, β 3 class III | AIF1/Iba1, allograft inflammatory factor 1 | α-synuclein | CA1, cornu ammonis field1 | RT, room temperature | ILVs, intraluminal vesicles | LAMP2A/Lamp2a, lysosomal-associated membrane protein 2, isoform A | MAP2, microtubule-associated protein 2 | SYP, synaptophysin | CD63, CD63 molecule | LN, Lewy neuritis | ALP, autophagy-lysosomal pathway | RAB11A/rab11, member RAS oncogene family | 1 | secretion | EV, empty vector | protein aggregation | TNF/TNFa, tumor necrosis factor α | WT-SNCA, wild-type α-synuclein | CSF, cerebrospinal fluid | RBFOX3/NeuN, RNA binding protein, fox-1 homolog (C. elegans) 3 | DLB, dementia with Lewy bodies | CM, conditioned medium | tg, transgenic | Parkinson disease | ML, molecular layer | ACTB/bAct, actin, β | ER, endoplasmatic reticulum | synucleinopathies | SL, stratum lacunosum; SNCA/aSyn | SNCAIP/Sph1, synphilin-1 | CMA, chaperone-mediated autophagy | inflammation | Neoctx, neocortex | UPS, ubiquitin proteasome system | IL6/IL-6, interleukin-6 | N, neuron | LB, Lewy bodies | MVBs, multivesicular bodies | PS, phosphatidylserine | Hippo, hippocampus | AK, adenylate kinase | Protein aggregation | Lysosomal degradation | Secretion | Synucleinopathies | Inflammation | CALCIUM-DEPENDENT MANNER | CHAPERONE-MEDIATED AUTOPHAGY | LEWY BODY DISEASE | alpha-synuclein | CELL-DEATH | CELL BIOLOGY | TRANSMISSION | MULTIVESICULAR BODIES | PROTEIN-DEGRADATION | NEURONS | PARKINSONS-DISEASE | Animals | Rats, Wistar | Humans | Cells, Cultured | Mice, Transgenic | Signal Transduction - physiology | Autophagy - physiology | Mice | Neurons - metabolism | Parkinson Disease - metabolism | Lewy Bodies - metabolism | alpha-Synuclein - metabolism
GFAP, glial fibrillary acidic protein | HSPA8/Hsc70, heat shock 70kDa protein 8 | lysosomal degradation | BafA1, bafilomycinA | CASP3/aCasp3, caspase-3 | ESCRT, endosomal sorting complex required for transport | PF, particle fraction | ANXA5, annexin A5 | SNCA-T, tagged α-synuclein | PDGFB/PDGFb, platelet-derived growth factor subunit b | PD, Parkinson disease | S100B/S100b, S100 calcium-binding protein B | HRP, horseradish peroxidase | TUBB3/b-III-Tub, tubulin, β 3 class III | AIF1/Iba1, allograft inflammatory factor 1 | α-synuclein | CA1, cornu ammonis field1 | RT, room temperature | ILVs, intraluminal vesicles | LAMP2A/Lamp2a, lysosomal-associated membrane protein 2, isoform A | MAP2, microtubule-associated protein 2 | SYP, synaptophysin | CD63, CD63 molecule | LN, Lewy neuritis | ALP, autophagy-lysosomal pathway | RAB11A/rab11, member RAS oncogene family | 1 | secretion | EV, empty vector | protein aggregation | TNF/TNFa, tumor necrosis factor α | WT-SNCA, wild-type α-synuclein | CSF, cerebrospinal fluid | RBFOX3/NeuN, RNA binding protein, fox-1 homolog (C. elegans) 3 | DLB, dementia with Lewy bodies | CM, conditioned medium | tg, transgenic | Parkinson disease | ML, molecular layer | ACTB/bAct, actin, β | ER, endoplasmatic reticulum | synucleinopathies | SL, stratum lacunosum; SNCA/aSyn | SNCAIP/Sph1, synphilin-1 | CMA, chaperone-mediated autophagy | inflammation | Neoctx, neocortex | UPS, ubiquitin proteasome system | IL6/IL-6, interleukin-6 | N, neuron | LB, Lewy bodies | MVBs, multivesicular bodies | PS, phosphatidylserine | Hippo, hippocampus | AK, adenylate kinase | Protein aggregation | Lysosomal degradation | Secretion | Synucleinopathies | Inflammation | CALCIUM-DEPENDENT MANNER | CHAPERONE-MEDIATED AUTOPHAGY | LEWY BODY DISEASE | alpha-synuclein | CELL-DEATH | CELL BIOLOGY | TRANSMISSION | MULTIVESICULAR BODIES | PROTEIN-DEGRADATION | NEURONS | PARKINSONS-DISEASE | Animals | Rats, Wistar | Humans | Cells, Cultured | Mice, Transgenic | Signal Transduction - physiology | Autophagy - physiology | Mice | Neurons - metabolism | Parkinson Disease - metabolism | Lewy Bodies - metabolism | alpha-Synuclein - metabolism
Journal Article
Neuromethods, ISSN 0893-2336, 2016, Volume 105, pp. 115 - 123
Journal Article
Cell, ISSN 0092-8674, 10/2012, Volume 151, Issue 3, pp. 483 - 496
A major unanswered question in neuroscience is whether there exists genomic variability between individual neurons of the brain, contributing to functional...
CELLS | GERMLINE | EVOLUTION | HUMAN GENOMES | NEUN | GENE | LANDSCAPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKT3 | TUMOR | GENERATION | CELL BIOLOGY | Genome-Wide Association Study | Trisomy | Humans | Male | Malformations of Cortical Development - genetics | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Proto-Oncogene Proteins c-akt - genetics | Caudate Nucleus - metabolism | Chromosomes, Human, Pair 18 | Long Interspersed Nucleotide Elements | Caudate Nucleus - cytology | Mosaicism | Neurons - metabolism | Mutation | Malformations of Cortical Development - pathology | Single-Cell Analysis | Child | Brain | Nervous system diseases | Neurosciences | Neurons | Analysis | Genomics | Genomes | Genetic aspects
CELLS | GERMLINE | EVOLUTION | HUMAN GENOMES | NEUN | GENE | LANDSCAPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKT3 | TUMOR | GENERATION | CELL BIOLOGY | Genome-Wide Association Study | Trisomy | Humans | Male | Malformations of Cortical Development - genetics | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Proto-Oncogene Proteins c-akt - genetics | Caudate Nucleus - metabolism | Chromosomes, Human, Pair 18 | Long Interspersed Nucleotide Elements | Caudate Nucleus - cytology | Mosaicism | Neurons - metabolism | Mutation | Malformations of Cortical Development - pathology | Single-Cell Analysis | Child | Brain | Nervous system diseases | Neurosciences | Neurons | Analysis | Genomics | Genomes | Genetic aspects
Journal Article
15.
Full Text
The reliability of the isotropic fractionator method for counting total cells and neurons
JOURNAL OF NEUROSCIENCE METHODS, ISSN 0165-0270, 10/2019, Volume 326
Background: The Isotropic Fractionator (IF) is a method to determine the cellular composition of nervous tissue. It has been mostly applied to assess variation...
NUMBER | QUANTIFICATION | SIZE | BIOCHEMICAL RESEARCH METHODS | Isotropic fractionator | Cell counting | NEUROSCIENCES | Neuron counting | UNBIASED STEREOLOGY | NEUN | CORTEX | Reliability | BRAIN
NUMBER | QUANTIFICATION | SIZE | BIOCHEMICAL RESEARCH METHODS | Isotropic fractionator | Cell counting | NEUROSCIENCES | Neuron counting | UNBIASED STEREOLOGY | NEUN | CORTEX | Reliability | BRAIN
Journal Article
Cellular and Molecular Neurobiology, ISSN 0272-4340, 7/2018, Volume 38, Issue 5, pp. 1137 - 1143
The early postnatal development of the A-layers of the dorsal lateral geniculate nucleus (LGNd) was investigated in kittens aged 0–34 days by...
Neurosciences | Biomedicine | NeuN | Neurobiology | Cat | Lateral geniculate nucleus | Parvalbumin | Postnatal development | Cell Biology | X-CELLS | MARKER | FERRET | ANTIGEN NEUN | NEUROSCIENCES | CELL BIOLOGY | ORGANIZATION | RETINAL GANGLION-CELLS | PERIGENICULATE NUCLEUS | Y-CELLS | PROJECTIONS | PRENATAL DEVELOPMENT | Immunohistochemistry | Physiological aspects | Laminated materials
Neurosciences | Biomedicine | NeuN | Neurobiology | Cat | Lateral geniculate nucleus | Parvalbumin | Postnatal development | Cell Biology | X-CELLS | MARKER | FERRET | ANTIGEN NEUN | NEUROSCIENCES | CELL BIOLOGY | ORGANIZATION | RETINAL GANGLION-CELLS | PERIGENICULATE NUCLEUS | Y-CELLS | PROJECTIONS | PRENATAL DEVELOPMENT | Immunohistochemistry | Physiological aspects | Laminated materials
Journal Article
International Journal of Morphology, ISSN 0717-9367, 12/2016, Volume 34, Issue 4, pp. 1362 - 1368
Journal Article
Neuroscience Letters, ISSN 0304-3940, 10/2019, Volume 711, p. 134414
Pattern separation aids cognitive flexibility by reducing interference between closely related memories. Dentate gyrus (DG) neurogenesis may facilitate pattern...
BrdU-NeuN | Cognitive flexibility | Neurogenesis | Doublecortin | Hippocampus | ADULT NEUROGENESIS | TIME | NEUROSCIENCES | PATTERN SEPARATION | MOSSY CELLS | MEMORY | CONNECTIVITY | PERIOD | NEURONS | DENTATE GYRUS | EXPRESSION
BrdU-NeuN | Cognitive flexibility | Neurogenesis | Doublecortin | Hippocampus | ADULT NEUROGENESIS | TIME | NEUROSCIENCES | PATTERN SEPARATION | MOSSY CELLS | MEMORY | CONNECTIVITY | PERIOD | NEURONS | DENTATE GYRUS | EXPRESSION
Journal Article