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Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 31, pp. 25927 - 25940
The beta-site amyloid precursor protein-cleaving enzyme BACE1 is a prime drug target for Alzheimer disease. However, the function and the physiological... 
ALZHEIMERS BETA-SECRETASE | CLOSE HOMOLOG | OLFACTORY SENSORY NEURONS | NEURITE OUTGROWTH | MICE DEFICIENT | PERIPHERAL NERVOUS-SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | GATED SODIUM-CHANNELS | SPINAL-CORD-INJURY | AMYLOID PRECURSOR PROTEIN | GAMMA-SECRETASE | Cell Adhesion Molecules - chemistry | Cell Adhesion Molecules - genetics | Neural Cell Adhesion Molecule L1 - genetics | Brain - enzymology | Cercopithecus aethiops | Molecular Sequence Data | Brain - metabolism | Protease Inhibitors - pharmacology | Synapses - metabolism | Proteolysis | Neurons - secretion | Neurons - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Amino Acid Sequence | Synapses - drug effects | Mutagenesis, Site-Directed | Aspartic Acid Endopeptidases - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Synapses - enzymology | Cell Adhesion Molecules - metabolism | Amino Acid Motifs | Mice, Knockout | Brain - drug effects | Amyloid Precursor Protein Secretases - metabolism | Peptide Fragments - chemistry | Animals | Proteome - secretion | Aspartic Acid Endopeptidases - metabolism | Neurons - enzymology | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Primary Cell Culture | Neural Cell Adhesion Molecule L1 - chemistry | COS Cells | Amino Acid Substitution | BACE1 | Neural Adhesion | Alzheimers Disease | Neurons | Protease | CHL1 | Neurobiology | Proteomics | Axon | Axon Guidance
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2007, Volume 27, Issue 3, pp. 590 - 603
Axonal initial segments (IS) and nodes of Ranvier are functionally important membrane subdomains in which the clustering of electrogenic channels enables... 
Retention vs targeting | Ankyrin | Initial segment | Plasma membrane (axolemma) | L1 CAMs | Trafficking | retention vs targeting | NERVOUS-SYSTEM | initial segment | plasma membrane (axolemma) | GATED SODIUM-CHANNELS | ACTION-POTENTIAL INITIATION | BETA-IV SPECTRIN | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | ankyrin | PREMYELINATED AXONS | STRUCTURAL REQUIREMENTS | SINGLE-PARTICLE TRACKING | EXTRACELLULAR-MATRIX | MEMBRANE-PROTEINS | trafficking | Cell Adhesion Molecules - genetics | Multigene Family | Protein Binding - genetics | Cell Adhesion Molecules - physiology | Humans | Neural Cell Adhesion Molecule L1 - genetics | Nerve Growth Factors - metabolism | Neural Cell Adhesion Molecule L1 - physiology | Neurons - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Nerve Growth Factors - physiology | Cell Adhesion Molecules, Neuron-Glia - metabolism | Cell Line | Cell Adhesion Molecules, Neuron-Glia - physiology | Neurons - chemistry | Cell Adhesion Molecules - biosynthesis | Neural Cell Adhesion Molecule L1 - biosynthesis | Cells, Cultured | Axons - metabolism | Rats | Axons - chemistry | Ankyrins - physiology | Nerve Growth Factors - biosynthesis | Cell Adhesion Molecules - metabolism | Ankyrins - biosynthesis | Animals | Nerve Growth Factors - genetics | Ankyrins - metabolism | Cell Adhesion Molecules, Neuron-Glia - biosynthesis
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2008, Volume 27, Issue 11, pp. 1549 - 1562
Axonal receptors for class 3 semaphorins (Sema3s) are heterocomplexes of neuropilins (Nrps) and Plexin‐As signalling coreceptors. In the developing cerebral... 
focal adhesion | cerebral cortex | receptor | semaphorins | axon guidance | Cerebral cortex | Axon guidance | Receptor | Semaphorins | Focal adhesion | NERVOUS-SYSTEM | TYROSINE PHOSPHORYLATION | CELL MOTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | MOLECULE L1 | MICE LACKING | CELL BIOLOGY | INTEGRIN FUNCTION | GROWTH | Signal Transduction | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Neuropilin-1 - metabolism | Neural Cell Adhesion Molecule L1 - genetics | Axons - metabolism | Receptors, Cell Surface - metabolism | Semaphorin-3A - metabolism | Cell Adhesion | Cerebral Cortex - cytology | Nerve Tissue Proteins - genetics | Cerebral Cortex - metabolism | Nerve Tissue Proteins - metabolism | Animals | Growth Cones - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Mutant Strains | Cerebral Cortex - growth & development | Mice | Neural Cell Adhesion Molecule L1 - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Receptors, Cell Surface - genetics | Signal transduction | Genetics | Biochemistry | Molecular biology | Cell adhesion & migration | Growth Cones | Focal Adhesion Protein-Tyrosine Kinases | Neural Cell Adhesion Molecule L1 | Receptors, Cell Surface | Cerebral Cortex | Nerve Tissue Proteins | Cellular Biology | Neuropilin-1 | Life Sciences | Axons | Semaphorin-3A | Mitogen-Activated Protein Kinase 1 | Mitogen-Activated Protein Kinase 3
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 9/2016, Volume 53, Issue 7, pp. 4461 - 4483
Lack of permissive mechanisms and abundance of inhibitory molecules in the lesioned central nervous system of adult mammals contribute to the failure of... 
Femoral nerve injury | Neurology | Neurosciences | Biomedicine | Neurobiology | Neuronal survival | Small molecule | Spinal cord injury | Cell adhesion molecule L1 | Neurite outgrowth | Cell Biology | IMMUNOGLOBULIN SUPERFAMILY | MICE DEFICIENT | SPINAL-CORD | NERVE INJURY | NEUROSCIENCES | POLYSIALIC ACID | RECOVERY | TRAUMATIC BRAIN-INJURY | ISCHEMIA-REPERFUSION | NF-KAPPA-B | Microglia - metabolism | Small Molecule Libraries - pharmacology | Astrocytes - pathology | Male | Duloxetine Hydrochloride - pharmacology | Femoral Nerve - injuries | Extracellular Signal-Regulated MAP Kinases - metabolism | Stilbenes - pharmacology | Motor Neurons - pathology | Myelin Sheath - metabolism | Spinal Cord Injuries - pathology | Proteolysis - drug effects | Microglia - pathology | Female | Neurons - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Phosphorylation - drug effects | Femoral Nerve - drug effects | Motor Neurons - drug effects | Neural Cell Adhesion Molecule L1 - agonists | Astrocytes - drug effects | Cell Survival - drug effects | Glucosides - pharmacology | Microglia - drug effects | Mice, Inbred C57BL | Cells, Cultured | Neuronal Outgrowth - drug effects | Peptides - pharmacology | Cell Movement - drug effects | Animals | Nerve Regeneration - drug effects | Cell Proliferation - drug effects | Spinal Cord Injuries - physiopathology | Astrocytes - metabolism | Neurons | Analysis | Molecules | Spinal cord injuries | Cell adhesion & migration
Journal Article
Current Opinion in Neurobiology, ISSN 0959-4388, 2008, Volume 18, Issue 3, pp. 245 - 250
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2018, Volume 32, Issue 3, pp. 1364 - 1374
Journal Article
Journal Article