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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 518 - 522
Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that... 
CELLS | ZEBRAFISH | GENE | MULTIDISCIPLINARY SCIENCES | KINASE | CARBAMOYL-PHOSPHATE SYNTHETASE | INHIBITOR | LEFLUNOMIDE | EXPRESSION | DISCOVERY | Transcription, Genetic - drug effects | Humans | Neural Crest - pathology | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Stem Cells - cytology | Zebrafish - embryology | Cell Lineage - drug effects | Oxidoreductases Acting on CH-CH Group Donors - antagonists & inhibitors | Neural Crest - metabolism | Melanoma - genetics | Neural Crest - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Proto-Oncogene Proteins B-raf - chemistry | Animals, Genetically Modified | Rats | Genes, p53 - genetics | Melanoma - pathology | Zebrafish - genetics | Neural Crest - drug effects | Isoxazoles - pharmacology | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Transcription, Genetic - physiology | Animals | Cell Differentiation - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Stem Cells - drug effects | Stem Cells - pathology | Mice | Isoxazoles - therapeutic use | Amino Acid Substitution | Care and treatment | Gene mutations | Melanoma | Physiological aspects | Genetic aspects | Research | Tumor proteins | Health aspects | Risk factors | Mutation | Gene expression | Chemicals | Stem cells | Tumors
Journal Article
Journal Article
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 01/2013, Volume 373, Issue 2, pp. 300 - 309
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 07/2016, Volume 55, pp. 111 - 118
Journal Article
Development (Cambridge), ISSN 0950-1991, 04/2015, Volume 142, Issue 7, pp. 1357 - 1367
Bone morphogenetic protein (BMP) signaling plays many roles in skull morphogenesis. We have previously reported that enhanced BMP signaling through the BMP... 
Craniofacial development | Neural crest cell | BMP | MDM2 | Nasal septum | SMAD | Apoptosis | P53 | SEPTAL CARTILAGE | FOREBRAIN DEVELOPMENT | DAMAGE-INDUCED PHOSPHORYLATION | DEVELOPMENTAL BIOLOGY | p53 | PROGRAMMED CELL-DEATH | TUMOR-SUPPRESSOR | NULL MICE | RABBIT SNOUT GROWTH | VOMERAL BONE DEFECT | TRANSGENIC MICE | Embryo, Mammalian - drug effects | Nose - embryology | Chondrogenesis - drug effects | Apoptosis - drug effects | Mesoderm - drug effects | Embryo, Mammalian - metabolism | Neural Crest - metabolism | Embryo Loss - metabolism | Toluene - analogs & derivatives | Fibroblast Growth Factors - metabolism | Proteolysis - drug effects | Bone Morphogenetic Proteins - metabolism | Nasal Cartilages - abnormalities | Nasal Cartilages - embryology | Cell Nucleus - metabolism | Embryo Loss - pathology | Protein Binding - drug effects | Integrases - metabolism | Toluene - pharmacology | Proto-Oncogene Proteins c-mdm2 - metabolism | Nasal Cartilages - pathology | Nose - metabolism | Animals, Newborn | Cell Survival - drug effects | Embryo, Mammalian - pathology | Mesoderm - embryology | Benzothiazoles - pharmacology | Tumor Suppressor Protein p53 - metabolism | Bone Morphogenetic Protein Receptors, Type I - metabolism | Mutation - genetics | Neural Crest - drug effects | Animals | Signal Transduction - drug effects | Neural Crest - embryology | Morphogenesis - drug effects | Mice | Cell Nucleus - drug effects | Nasal Cartilages - metabolism | Mesoderm - pathology | Smad Proteins - metabolism
Journal Article
Journal Article
Science, ISSN 0036-8075, 8/2002, Volume 297, Issue 5582, pp. 848 - 851
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 13, Issue 2, pp. 129 - 140
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, p. e18784
Background: The aggressiveness of melanoma tumors is likely to rely on their well-recognized heterogeneity and plasticity. Melanoma comprises... 
INITIATING CELLS | IN-VITRO | DEFINED FACTORS | METASTASIS | B-16 MELANOMA | BIOLOGY | REGULATORY T-CELLS | EXPRESSION | HUMAN-MALIGNANT MELANOMA | CANCER STEM-CELLS | MHC CLASS-II | Embryonic Stem Cells - metabolism | Immunomodulation - drug effects | Transcription, Genetic - drug effects | Neoplastic Stem Cells - drug effects | Genes, Neoplasm | Humans | Neural Crest - pathology | Spheroids, Cellular - pathology | Gene Expression Profiling | Cell Lineage - drug effects | Neural Crest - metabolism | Neoplastic Stem Cells - metabolism | Melanoma - genetics | Neoplastic Stem Cells - pathology | Spheroids, Cellular - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Neoplasm Invasiveness | Spheroids, Cellular - metabolism | Melanoma - pathology | Neural Crest - drug effects | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Movement - drug effects | Phenotype | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Melanoma - immunology | Pluripotent Stem Cells - drug effects | Culture Media - pharmacology | Cell Proliferation - drug effects | Metastasis | T cells | Gene expression | Analysis | Stem cells | Cancer | Cell proliferation | Transcription factors | Mesenchyme | Oct-4 protein | Lymphocytes T | Activation | Assaying | Immunity | Metastases | Skin cancer | Heterogeneity | Genotype & phenotype | Cell activation | KLF4 protein | Lymphocytes | Mathematical models | Immune system | Subpopulations | Antigens | Aggressive behavior | Cytokines | Immunomodulation | Tumor cells | Invasiveness | Melanoma | Cultures | Tumorigenicity | Neural crest | Embryos | Spheroids | Studies | Ligands | Prostate cancer | Cell migration | Chemokines | Tumors | Apoptosis | Cell Proliferation | Gene Expression Regulation, Neoplastic | Neoplastic Stem Cells | Cellular Biology | Neural Crest | Life Sciences | Cell Lineage | Pluripotent Stem Cells | Culture Media | Transcription, Genetic | Cell Differentiation | Transcription Factors | Embryonic Stem Cells | Spheroids, Cellular | Cell Movement
Journal Article