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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 518 - 522
Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that... 
CELLS | ZEBRAFISH | GENE | MULTIDISCIPLINARY SCIENCES | KINASE | CARBAMOYL-PHOSPHATE SYNTHETASE | INHIBITOR | LEFLUNOMIDE | EXPRESSION | DISCOVERY | Transcription, Genetic - drug effects | Humans | Neural Crest - pathology | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Stem Cells - cytology | Zebrafish - embryology | Cell Lineage - drug effects | Oxidoreductases Acting on CH-CH Group Donors - antagonists & inhibitors | Neural Crest - metabolism | Melanoma - genetics | Neural Crest - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Proto-Oncogene Proteins B-raf - chemistry | Animals, Genetically Modified | Rats | Genes, p53 - genetics | Melanoma - pathology | Zebrafish - genetics | Neural Crest - drug effects | Isoxazoles - pharmacology | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Transcription, Genetic - physiology | Animals | Cell Differentiation - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Stem Cells - drug effects | Stem Cells - pathology | Mice | Isoxazoles - therapeutic use | Amino Acid Substitution | Care and treatment | Gene mutations | Melanoma | Physiological aspects | Genetic aspects | Research | Tumor proteins | Health aspects | Risk factors | Mutation | Gene expression | Chemicals | Stem cells | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 4, pp. E630 - E638
Journal Article
Mechanisms of Development, ISSN 0925-4773, 2011, Volume 128, Issue 3, pp. 200 - 207
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1126 - 15
Journal Article
Developmental Biology, ISSN 0012-1606, 11/2013, Volume 383, Issue 2, pp. 239 - 252
Neural crest cells (NCCs) are physically responsible for craniofacial skeleton formation, pharyngeal arch artery remodeling and cardiac outflow tract septation... 
Neural crest cell | Persistent truncus arteriosus | GTPase | Migration | Cdc42 | Craniofacial malformation | CARDIAC OUTFLOW TRACT | HEART FIELD | MOUSE EMBRYOS | G-PROTEINS | DEVELOPMENTAL BIOLOGY | NUCLEOTIDE EXCHANGE FACTOR | MICE | FOCAL ADHESION KINASE | ACTIN CYTOSKELETON | RHO-GTPASES | Bone Morphogenetic Protein 2 - pharmacology | Embryo, Mammalian - drug effects | Neural Crest - pathology | Actins - metabolism | Craniofacial Abnormalities - embryology | Male | cdc42 GTP-Binding Protein - metabolism | Pseudopodia - drug effects | Cardiovascular Abnormalities - pathology | Gene Deletion | Thymus Gland - pathology | Craniofacial Abnormalities - pathology | Female | Neural Crest - enzymology | Embryo, Mammalian - pathology | Osteogenesis - drug effects | Genotype | Cardiovascular Abnormalities - embryology | Thymus Gland - drug effects | Enzyme Activation - drug effects | Embryo, Mammalian - abnormalities | Mice, Knockout | Neural Crest - drug effects | Cardiovascular Abnormalities - enzymology | Cell Movement - drug effects | Thymus Gland - abnormalities | Phenotype | Animals | Pseudopodia - metabolism | Cell Differentiation - drug effects | Craniofacial Abnormalities - enzymology | Cytoskeleton - metabolism | Morphogenesis - drug effects | Mice | Crosses, Genetic | Embryonic development | Lubrication and lubricants | Analysis | Medical genetics | Bone morphogenetic proteins | Neovascularization | Binding proteins | Protein binding
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47794
The neural crest is a population of multipotent cells that migrates extensively throughout vertebrate embryos to form diverse structures. Mice mutant for the... 
EPITHELIAL-MESENCHYMAL TRANSITION | STEM-CELLS | METHYLATION | ICF SYNDROME | MULTIDISCIPLINARY SCIENCES | DNMT3B | MAMMALIAN DEVELOPMENT | GENERATION | SPECIFICATION | EXPRESSION | EMBRYOGENESIS | Wnt1 Protein - genetics | Embryo, Mammalian | Heart - embryology | Wnt1 Protein - metabolism | Branchial Region - enzymology | Skull - enzymology | DNA (Cytosine-5-)-Methyltransferases - metabolism | Neurogenesis - genetics | Gene Expression Regulation, Developmental | Mesoderm - enzymology | Integrases - metabolism | Cell Differentiation | Neural Crest - enzymology | Mesoderm - embryology | SOXE Transcription Factors - metabolism | Mice, Transgenic | Basal Ganglia - enzymology | Skull - embryology | Basal Ganglia - embryology | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Neural Crest - embryology | Mice | Mutation | Integrases - genetics | Branchial Region - embryology | Cell Movement | SOXE Transcription Factors - genetics | Epigenetic inheritance | Embryonic development | Research | Methyltransferases | Health aspects | DNA | Heart | Spinal cord | Leukocyte migration | Mesoderm | Nervous system | Biology | Defects | Morphogenesis | DNA methylation | Heart diseases | Mesendoderm | Deoxyribonucleic acid--DNA | Septum | Derivatives | Gene expression | Embryos | Neural crest | Sox10 protein | Ganglia | Mutants | Epigenetics | DNA methyltransferase | Skull | Ventricle | Laboratory animals | Cell migration | Deoxyribonucleic acid
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2008, Volume 105, Issue 44, pp. 17115 - 17120
Journal Article
Developmental Biology, ISSN 0012-1606, 01/2016, Volume 409, Issue 1, pp. 152 - 165
Journal Article
Journal Article