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Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
.... Here, we describe the derivation and characterization, including single-cell RNA-seq, of neocortical and spinal cord neuroepithelial stem (NES... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 02/2017, Volume 18, Issue 9, pp. 2113 - 2123
Journal Article
International journal of nanomedicine, ISSN 1178-2013, 2018, Volume 13, pp. 6265 - 6277
...) and induced pluripotent stem cells -derived neural stem cells (iPSC-NSCs), a combined cell transplantation strategy, were prepared and characterized... 
spinal cord injury | polycaprolactone | induced pluripotent stem cells | SURVIVAL | APOPTOSIS | MYELINATION | REGENERATION | NANOSCIENCE & NANOTECHNOLOGY | DISTANCE AXONAL GROWTH | TRANSPLANTATION | PLURIPOTENT STEM-CELLS | RECOVERY | ACTIVATED SCHWANN-CELLS | PHARMACOLOGY & PHARMACY | DIFFERENTIATION | Polycaprolactone | Tissue Engineering - methods | Rats, Wistar | Cell Separation | Coculture Techniques | Induced Pluripotent Stem Cells - ultrastructure | Nerve Growth Factors - metabolism | Fetal Blood - cytology | Neural Stem Cells - cytology | Neural Stem Cells - ultrastructure | Schwann Cells - cytology | Tissue Scaffolds - chemistry | Behavior, Animal | Polyesters - chemistry | Animals | Schwann Cells - ultrastructure | Spinal Cord - pathology | Axons - pathology | Leukocytes, Mononuclear - cytology | Mice | Induced Pluripotent Stem Cells - cytology | Spinal Cord Injuries - therapy | Neural Stem Cells - metabolism | Usage | Tissue engineering | Stem cells | Nerve growth factor | Spinal cord injuries | Transplantation | Embryonic stem cells | Health aspects | Medical research | Transplants & implants | Nervous system | FDA approval | Bone surgery | Biological activity | Quality of life | Cell adhesion & migration | Studies | Ethics | Hospitals | Researchers | Research methodology | Biocompatibility | Umbilical cord | Laboratory animals | Growth factors | Spinal cord injury | Induced pluripotent stem cells
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 34, pp. 12438 - 12443
The apical domain of embryonic (radial glia) and adult (B1 cells) neural stem cells (NSCs) contains a primary cilium... 
Brain | Adult stem cells | Hydrocephalus | Neurons | Neuroglia | Neural stem cells | Mice | Progenitor cells | Neurogenesis | Cilia | Olfactory bulb | Gli1 | Subependyma | Adult neurogenesis | Ventricular zone | INTRAFLAGELLAR TRANSPORT PROTEINS | NEURONAL MIGRATION | adult neurogenesis | ventricular zone | olfactory bulb | STEM-CELLS | SONIC HEDGEHOG | DISEASE GENE | MULTIDISCIPLINARY SCIENCES | ADULT MAMMALIAN BRAIN | SUBVENTRICULAR ZONE | CEREBRAL-CORTEX | OLFACTORY-BULB | subependyma | REPRESSOR FUNCTIONS | Cilia - physiology | Embryonic Stem Cells - metabolism | Glial Fibrillary Acidic Protein - genetics | Brain - embryology | Cell Proliferation | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Hedgehog Proteins - physiology | Brain - growth & development | Embryonic Stem Cells - classification | Embryonic Stem Cells - ultrastructure | Glial Fibrillary Acidic Protein - metabolism | Neural Stem Cells - ultrastructure | Gene Knockdown Techniques | Neural Stem Cells - classification | Brain - metabolism | Tumor Suppressor Proteins - genetics | Nestin - genetics | Kinesin - genetics | Female | Kinesin - antagonists & inhibitors | Animals, Newborn | Tumor Suppressor Proteins - metabolism | Signal Transduction | Mice, Transgenic | Kinesin - metabolism | Nestin - metabolism | Pregnancy | Animals | Neurogenesis - physiology | Neural Stem Cells - metabolism | Physiological aspects | Research | Neurological research | Cilia and ciliary motion | Biological Sciences
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2002, Volume 110, Issue 4, pp. 429 - 441
The adult brain is extremely vulnerable to various insults. The recent discovery of neural progenitors in adult mammals, however, raises the possibility of... 
RAT SPINAL-CORD | GERBIL HIPPOCAMPUS | STEM-CELLS | TRANSIENT FOREBRAIN ISCHEMIA | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROBLAST-GROWTH-FACTOR | CENTRAL-NERVOUS-SYSTEM | ADULT MAMMALIAN BRAIN | SUBVENTRICULAR ZONE | SYNAPTIC PLASTICITY | CELL BIOLOGY | Neural Pathways - drug effects | Recovery of Function - drug effects | Nerve Regeneration - physiology | Neuronal Plasticity - drug effects | Male | Dendrites - ultrastructure | Nerve Degeneration - metabolism | Neuronal Plasticity - physiology | Recovery of Function - physiology | Hippocampus - ultrastructure | Pyramidal Cells - drug effects | Organ Culture Techniques | Dendrites - drug effects | Synapses - drug effects | Neural Pathways - growth & development | Rats | Synapses - ultrastructure | Brain Ischemia - physiopathology | Cell Division - drug effects | Stem Cells - ultrastructure | Cell Division - physiology | Cell Movement - drug effects | Brain Ischemia - drug therapy | Nerve Regeneration - drug effects | Growth Substances - pharmacology | Pyramidal Cells - metabolism | Rats, Wistar | Microtubule-Associated Proteins - metabolism | Nerve Degeneration - physiopathology | Brain Ischemia - metabolism | Hippocampus - drug effects | Stem Cells - metabolism | Excitatory Postsynaptic Potentials - drug effects | Cell Movement - physiology | Excitatory Postsynaptic Potentials - physiology | Synapses - metabolism | Up-Regulation - physiology | Hippocampus - growth & development | Pyramidal Cells - ultrastructure | Dendrites - metabolism | Transcription Factors - genetics | Microscopy, Electron | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Growth Substances - therapeutic use | Stem Cells - drug effects | Neural Pathways - ultrastructure | Nerve Degeneration - drug therapy | Neural circuitry | Neurons | Growth | Physiological aspects | Hippocampus (Brain) | Developmental neurology | Research
Journal Article
Journal Article