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Cellular and Molecular Life Sciences, ISSN 1420-682X, 10/2014, Volume 71, Issue 19, pp. 3659 - 3683
Influenza viruses are major human pathogens responsible for respiratory diseases affecting millions of people worldwide and characterized by high morbidity and... 
Life Sciences | Biochemistry, general | Signaling pathways | New antivirals | Virus–host interaction | Life Sciences, general | Drug targets | Influenza virus | Drug discovery | Biomedicine general | Cell Biology | Virus-host interaction | VIRAL-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR EXPORT | POTENT INHIBITORS | CELL BIOLOGY | NS1 PROTEIN | IN-VITRO | CONFORMATIONAL-CHANGE | STRUCTURE-BASED DISCOVERY | SIALIDASE FUSION PROTEIN | SMALL-MOLECULE INHIBITORS | RNA-POLYMERASE | Virus Replication - drug effects | Antiviral Agents - pharmacology | DNA-Directed RNA Polymerases - antagonists & inhibitors | Antiviral Agents - therapeutic use | Humans | Neuraminidase - metabolism | Orthomyxoviridae - metabolism | Virus Internalization - drug effects | Hemagglutinins - immunology | Hemagglutinins - metabolism | Viral Core Proteins - antagonists & inhibitors | Antibodies, Neutralizing - immunology | Viral Matrix Proteins - antagonists & inhibitors | Viral Core Proteins - metabolism | Influenza, Human - virology | Neuraminidase - antagonists & inhibitors | Viral Matrix Proteins - metabolism | Orthomyxoviridae - drug effects | Influenza, Human - drug therapy | DNA-Directed RNA Polymerases - metabolism | Influenza viruses | Antiviral agents | Influenza | Vaccination | Mortality | Drug resistance | Health aspects | Drug approval | Signal transduction | Pharmacology | Antiviral drugs
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2016, Volume 60, Issue 11, pp. 6679 - 6691
T-705 (favipiravir) is a new antiviral agent in advanced clinical development for influenza therapy. It is supposed to act as an alternative substrate for the... 
NUCLEOTIDE POOL | IN-VITRO | NEURAMINIDASE INHIBITORS | MECHANISM | TRANSCRIPTION | BIOLOGICAL EVALUATION | POLYMERASE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | ANTIVIRAL AGENT | LETHAL MUTAGENESIS | DNA-Directed RNA Polymerases - antagonists & inhibitors | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Influenza A Virus, H3N2 Subtype - metabolism | Reassortant Viruses - genetics | Reassortant Viruses - drug effects | Structure-Activity Relationship | Influenza A Virus, H3N2 Subtype - genetics | IMP Dehydrogenase - genetics | Influenza A Virus, H1N1 Subtype - growth & development | Viral Proteins - metabolism | Influenza A Virus, H3N2 Subtype - growth & development | RNA, Viral - antagonists & inhibitors | Antiviral Agents - chemistry | Madin Darby Canine Kidney Cells | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H1N1 Subtype - metabolism | Amides - pharmacology | A549 Cells | Virus Replication - drug effects | Antiviral Agents - pharmacology | Reassortant Viruses - metabolism | RNA, Viral - biosynthesis | Viral Proteins - genetics | Viral Proteins - antagonists & inhibitors | DNA-Directed RNA Polymerases - genetics | Ribavirin - chemistry | Influenza A Virus, H1N1 Subtype - drug effects | Chick Embryo | Reassortant Viruses - growth & development | IMP Dehydrogenase - metabolism | Pyrazines - chemistry | Animals | Mutation - drug effects | Sequence Analysis, RNA | IMP Dehydrogenase - antagonists & inhibitors | Gene Expression Regulation, Viral | Dogs | Amides - chemistry | DNA-Directed RNA Polymerases - metabolism | Pyrazines - pharmacology | Ribavirin - pharmacology
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 8, pp. 4795 - 4803
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7468, pp. 551 - 555
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 1, pp. 287 - 299
Journal Article
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 4, Issue 4, pp. CD008965 - CD008965
Journal Article