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Nature, ISSN 0028-0836, 04/2017, Volume 544, Issue 7649, pp. 235 - 239
Journal Article
Neuron, ISSN 0896-6273, 09/2013, Volume 79, Issue 6, pp. 1152 - 1168
Genetic variation in neuregulin and its ErbB4 receptor has been linked to schizophrenia, although little is known about how they contribute to the disease... 
PARVALBUMIN-POSITIVE INTERNEURONS | GLUTAMIC-ACID DECARBOXYLASE | NEUREGULIN 3 NRG3 | CORTICAL GABAERGIC INTERNEURONS | GENE-EXPRESSION | FUNCTIONAL CONNECTIVITY | PSYCHIATRIC-DISORDERS | NEUROSCIENCES | PREFRONTAL CORTEX | CEREBRAL-CORTEX | WORKING-MEMORY | Interneurons - physiology | Receptor, Epidermal Growth Factor - genetics | Action Potentials - genetics | Synaptic Transmission - genetics | Parvalbumins - metabolism | Receptor, Epidermal Growth Factor - deficiency | Male | Schizophrenia - complications | Green Fluorescent Proteins - genetics | Schizophrenia - pathology | Statistics as Topic | Schizophrenia - genetics | Social Behavior | Cognition Disorders - etiology | Disease Models, Animal | Animals, Newborn | Maze Learning - physiology | Brain - physiopathology | RNA, Untranslated | Electroporation | Mice, Transgenic | Cognition Disorders - genetics | Transcription Factors - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Action Potentials - physiology | Nerve Tissue Proteins - metabolism | Proteins - genetics | Motor Activity - genetics | LIM-Homeodomain Proteins - genetics | Patch-Clamp Techniques | Phenotype | Animals | Proteins - metabolism | Brain - pathology | Glutamate Decarboxylase - metabolism | Mice | Receptors, GABA-A - metabolism | In Vitro Techniques | Receptor, ErbB-4 | Schizophrenia | Disease susceptibility | Genetic aspects | Biological products | Tissue engineering | Brain | Ultrasonic imaging | Rodents | Migration | Colleges & universities | Kinases | University colleges | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2018, Volume 14, Issue 8, pp. e1007568 - e1007568
We characterized the establishment of an Epidermal Growth Factor Receptor (EGFR) organizing center (EOC) during leg development in Drosophila melanogaster.... 
TRANSCRIPTION FACTORS | LIMB DEVELOPMENT | PROTEIN | IMAGINAL DISCS | GROWTH | WINGLESS | GENETICS & HEREDITY | GENE-EXPRESSION | RECEPTOR | SPECIFICATION | PROXIMAL-DISTAL AXIS | Wnt1 Protein - genetics | ErbB Receptors - genetics | Wnt1 Protein - physiology | Drosophila melanogaster - genetics | Drosophila Proteins - physiology | Receptors, Invertebrate Peptide - genetics | Gene Expression Regulation, Developmental | Gene Deletion | Organizers, Embryonic | Sp1 Transcription Factor - physiology | Transcription Factors - physiology | Signal Transduction | Imaginal Discs - physiology | Transforming Growth Factor beta - physiology | Neuregulins - physiology | Transcription Factors - genetics | Homeodomain Proteins - genetics | ErbB Receptors - physiology | Animals | Transforming Growth Factor beta - genetics | Enhancer Elements, Genetic | Sp1 Transcription Factor - genetics | Alleles | Receptors, Invertebrate Peptide - physiology | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | Neuregulins - genetics | Extremities - growth & development | Homeodomain Proteins - physiology | Animal development | Epidermal growth factor | Extremities, Lower | Drosophila | Physiological aspects | Genetic aspects | Research | Health aspects | Leg | CRISPR | Visualization | Epidermal growth factor receptors | Funding | Biochemistry | Genomes | Biology | Biophysics | Gene expression | Sp1 protein | Genotype & phenotype | Enhancers | Clonal deletion | Insects | Ligands | Imaginal discs | Index Medicus
Journal Article
PLoS biology, ISSN 1545-7885, 10/2018, Volume 16, Issue 10, pp. e3000027 - e3000027
Extensive apoptosis is often seen in patterning mutants, suggesting that tissues can detect and eliminate potentially harmful mis-specified cells. Here, we... 
TRANSFORMATION | GROWTH-FACTOR RECEPTOR | APOPTOSIS | HID | BIOCHEMISTRY & MOLECULAR BIOLOGY | WINGLESS | BIOLOGY | SEGMENTATION GENE | DEATH | HOMOLOG | MELANOGASTER | EXPRESSION | Drosophila melanogaster - embryology | ErbB Receptors - genetics | Cell Survival - genetics | Apoptosis - genetics | Male | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Receptors, Invertebrate Peptide - genetics | Female | Membrane Proteins - metabolism | Neuropeptides - genetics | Cell Survival - physiology | Neuregulins - metabolism | Genes, Insect | Epidermis - metabolism | ErbB Receptors - metabolism | Signal Transduction | Animals, Genetically Modified | Epidermal Growth Factor - genetics | Membrane Proteins - genetics | Epidermal Growth Factor - metabolism | Neuropeptides - metabolism | Body Patterning - physiology | Animals | Epidermis - embryology | Ligands | Receptors, Invertebrate Peptide - metabolism | Apoptosis - physiology | Drosophila Proteins - genetics | Mutation | Neuregulins - genetics | Body Patterning - genetics | Pattern formation | Patterning | Cell survival | Segmentation | Epidermal growth factor receptors | Transforming growth factor | Genes | Drosophila | Epidermis | Gene expression | Embryos | Survival | Mutants | Signaling | Epidermal growth factor | Insects | Cell death | Neuregulin | Growth factors | Apoptosis | Index Medicus
Journal Article
Current Biology, ISSN 0960-9822, 07/2006, Volume 16, Issue 13, pp. 1358 - 1365
The early embryo is emerging as a premiere model system for the computational analysis of gene regulation in development because most of the genes, and many of... 
DEVBIO | DNA-BINDING | NEUROECTODERM | COMMON ORGANIZATIONAL FEATURES | REGULATORY NETWORKS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DORSAL GRADIENT MORPHOGEN | TRANSCRIPTION | SEGMENTATION GENES | BINDING PROTEIN | MELANOGASTER | LAMBDA | Embryo, Nonmammalian - cytology | Transcription Factors - chemistry | Homeodomain Proteins - metabolism | Nervous System - metabolism | Embryo, Nonmammalian - metabolism | Molecular Sequence Data | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Computer Simulation | Drosophila - embryology | Membrane Proteins - metabolism | Nervous System - embryology | Nuclear Proteins - genetics | Snail Family Transcription Factors | Neuregulins - metabolism | Drosophila - genetics | Membrane Proteins - genetics | Nuclear Proteins - metabolism | Drosophila Proteins - chemistry | Phosphoproteins - genetics | Transcription Factors - genetics | Homeodomain Proteins - chemistry | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Sequence Alignment | Animals | Enhancer Elements, Genetic | Membrane Proteins - chemistry | Twist-Related Protein 1 - genetics | Models, Genetic | Drosophila - metabolism | Drosophila Proteins - genetics | Mutation | Neuregulins - genetics | Twist-Related Protein 1 - metabolism | Genes, Developmental | Proteins | Embryonic development | Embryo | Computer-generated environments | Computer simulation | Analysis | Drosophila | Models | Genetic aspects | Gene expression | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 06/2005, Volume 8, Issue 6, pp. 745 - 751
The control of myelination by oligodendrocytes in the CNS is poorly understood. Here we show that LINGO-1 is an important negative regulator of this critical... 
NERVOUS-SYSTEM | NEUREGULIN | FYN TYROSINE KINASE | ACTIVATION | MORPHOLOGICAL-DIFFERENTIATION | SHEATH THICKNESS | SCHWANN-CELLS | EXPRESSION | NEUROSCIENCES | RECEPTOR FAMILY-MEMBER | MOLECULES | Oligodendroglia - metabolism | RNA Interference - drug effects | Central Nervous System - metabolism | Coculture Techniques | Humans | Rats, Long-Evans | Myelin-Associated Glycoprotein - genetics | Myelin-Associated Glycoprotein - metabolism | Proto-Oncogene Proteins c-fyn | Gene Expression Regulation, Developmental - genetics | rhoA GTP-Binding Protein - metabolism | Nerve Fibers, Myelinated - ultrastructure | Ranvier's Nodes - metabolism | Receptors, Cell Surface - antagonists & inhibitors | Central Nervous System - embryology | Oligodendroglia - ultrastructure | Ranvier's Nodes - ultrastructure | Myelin Sheath - metabolism | Central Nervous System - growth & development | Cell Differentiation - genetics | Oligodendroglia - drug effects | src-Family Kinases - metabolism | Myelin-Associated Glycoprotein - antagonists & inhibitors | RNA Interference - physiology | Nerve Fibers, Myelinated - metabolism | Proto-Oncogene Proteins - metabolism | Microscopy, Electron, Transmission | Nerve Fibers, Myelinated - drug effects | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Rats | Receptors, Cell Surface - metabolism | Proto-Oncogene Proteins - genetics | Nerve Tissue Proteins | Ranvier's Nodes - genetics | Signal Transduction - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Mice, Knockout | Membrane Proteins | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Myelin Sheath - genetics | Mice | Myelin Sheath - ultrastructure | src-Family Kinases - genetics | Receptors, Cell Surface - genetics | Myelination | Central nervous system | Physiological aspects | Oligodendroglia | Genetic aspects | Research | Diagnosis | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2019, Volume 15, Issue 3, pp. e1007857 - e1007857
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2015, Volume 5, Issue 1, pp. 17806 - 17806
How several signaling pathways are coordinated to generate complex organs through regulation of tissue growth and patterning is a fundamental question in... 
ENCODES | POINTED-P2 | GROWTH-FACTOR RECEPTOR | CELLS | PROTEIN | DROSOPHILA TRACHEAL SYSTEM | PATHWAY | MULTIDISCIPLINARY SCIENCES | BRANCHING MORPHOGENESIS | PROLIFERATION | MAMMARY-GLAND | Protein-Tyrosine Kinases - metabolism | ErbB Receptors - genetics | Fibroblast Growth Factors - genetics | Male | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | DNA-Binding Proteins - metabolism | Fibroblast Growth Factors - metabolism | Protein-Tyrosine Kinases - genetics | Receptors, Invertebrate Peptide - genetics | Gene Expression Regulation, Developmental | Air Sacs - cytology | Receptors, Fibroblast Growth Factor - genetics | Female | Neuregulins - metabolism | Proto-Oncogene Proteins - metabolism | Air Sacs - metabolism | ErbB Receptors - metabolism | Animals, Genetically Modified | Air Sacs - growth & development | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Larva | Receptors, Fibroblast Growth Factor - metabolism | Drosophila melanogaster - growth & development | Receptors, Invertebrate Peptide - metabolism | Drosophila Proteins - genetics | Neuregulins - genetics | Pattern formation | Fibroblast growth factor | Transcription factors | Leukocyte migration | Epidermal growth factor receptors | Muscles | Kinases | Cell adhesion & migration | Signal transduction | Epidermal growth factor | Insects | Ligands | Trachea | Metamorphosis | Cell migration | Index Medicus
Journal Article