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European Journal of Cancer, ISSN 0959-8049, 2016, Volume 67, pp. 130 - 140
Abstract Objectives Dose-finding trials are fundamental to develop novel drugs for children and adolescents with advanced cancer... 
Hematology, Oncology and Palliative Medicine | Innovative Therapies for Children with Cancer | Dose-finding trial | Prognostic factor | Phase I trial | Children | Adolescents | Survival | Life Sciences & Biomedicine | Oncology | Science & Technology | Osteosarcoma - drug therapy | Multivariate Analysis | Prognosis | Neuroectodermal Tumors, Primitive - drug therapy | Humans | Child, Preschool | Infant | Male | Neuroblastoma - mortality | Sarcoma, Ewing - mortality | Medulloblastoma - mortality | Ependymoma - drug therapy | Employment | Ependymoma - mortality | Sarcoma - mortality | Female | Rhabdomyosarcoma - drug therapy | Retrospective Studies | Child | Rhabdomyosarcoma - mortality | Schools | Osteosarcoma - mortality | Glioma - mortality | Neuroectodermal Tumors, Primitive - mortality | Europe | Proportional Hazards Models | Neoplasms - mortality | Therapies, Investigational | Survival Rate | Sarcoma - drug therapy | Neoplasms - drug therapy | Sarcoma, Ewing - drug therapy | Neuroblastoma - drug therapy | Adolescent | Medulloblastoma - drug therapy | Central Nervous System Neoplasms - drug therapy | Central Nervous System Neoplasms - mortality | Clinical Trials, Phase I as Topic | Glioma - drug therapy | Care and treatment | Patient outcomes | Children's hospitals | Oncology, Experimental | Clinical trials | Research | Health aspects | Cancer
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 04/2003, Volume 95, Issue 7, pp. 516 - 525
Hypoxia-inducible factor 1 alpha (HIF-1alpha), a component of HIF-1, is expressed in human tumors and renders cells able to survive and grow under hypoxic... 
Intercellular Signaling Peptides and Proteins - analysis | Neoplasms - metabolism | Vascular Endothelial Growth Factor A | G(M1) Ganglioside - analysis | Vascular Endothelial Growth Factors | Humans | Immunoblotting | Male | Transplantation, Heterologous | Hypoxia-Inducible Factor 1, alpha Subunit | Transcription Factors - drug effects | Endothelial Growth Factors - analysis | Carcinoma, Hepatocellular - drug therapy | Female | Neovascularization, Pathologic - prevention & control | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Carcinoma - drug therapy | Cell Hypoxia - drug effects | Enzyme-Linked Immunosorbent Assay | Liver Neoplasms - drug therapy | Angiogenesis Inhibitors - pharmacology | Platelet Endothelial Cell Adhesion Molecule-1 - analysis | Rats | Neoplasms - blood supply | Uterine Cervical Neoplasms - drug therapy | Stomach Neoplasms - drug therapy | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Precipitin Tests | Neoplasms - drug therapy | Indazoles - pharmacology | Transcription Factors - metabolism | Culture Media, Conditioned | Animals | Lymphokines - analysis | Neuroblastoma - drug therapy | Killer Cells, Natural - drug effects | Mice | Neovascularization, Pathologic - metabolism | Killer Cells, Natural - metabolism | Kidney Neoplasms - drug therapy | Antimitotic agents | Antineoplastic agents | Evaluation
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2010, Volume 363, Issue 14, pp. 1324 - 1334
Journal Article
Molecular cancer therapeutics, ISSN 1538-8514, 07/2018, Volume 17, Issue 7, pp. 1405 - 1415
Journal Article