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1. Full Text 177Lu-DOTATATE molecular radiotherapy for childhood neuroblastoma
by Gains, Jennifer E and Bomanji, Jamshed B and Fersht, Naomi L and Sullivan, Tracy and D'Souza, Derek and Sullivan, Kevin P and Aldridge, Matthew and Waddington, Wendy and Gaze, Mark N
Journal of Nuclear Medicine, ISSN 0161-5505, 07/2011, Volume 52, Issue 7, pp. 1041 - 1047
This study tested the principle that (68)Ga-DOTATATE PET/CT may be used to select children with primary refractory or relapsed high-risk neuroblastoma for... 
Lu-DOTATATE | Molecular radiotherapy | Childhood neuroblastoma | Targeted radionuclide therapy | Ga- DOTATATE | Somatostatin receptor imaging | Recurrence | Octreotide - analogs & derivatives | Humans | Child, Preschool | Male | Neuroblastoma - diagnostic imaging | Tomography, X-Ray Computed | Treatment Outcome | Positron-Emission Tomography | Octreotide - therapeutic use | Neuroblastoma - radiotherapy | Adolescent | Gallium Radioisotopes | Organometallic Compounds - therapeutic use | Female | Neuroblastoma - metabolism | Receptors, Somatostatin - metabolism | Child
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2. Full Text (17)7Lu-DOTATATE Molecular Radiotherapy for Childhood Neuroblastoma
by Gains, JE and Bomanji, JB and Fersht, NL and Sullivan, T and D'Souza, D and Sullivan, KP and Aldridge, M and Waddington, W and Gaze, MN
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 07/2011, Volume 52, Issue 7, pp. 1041 - 1047
This study tested the principle that Ga-68-DOTATATE PET/CT may be used to select children with primary refractory or relapsed high-risk neuroblastoma for... 
Y-90-DOTATOC | NEUROENDOCRINE TUMORS | childhood neuroblastoma | SOLID TUMORS | targeted radionuclide therapy | Ga-68-DOTATATE | molecular radiotherapy | RANDOMIZED-TRIAL | RADIOLABELED SOMATOSTATIN ANALOG | PET/CT | somatostatin receptor imaging | RECEPTORS | PHASE-I | DOSIMETRY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MEDIATED RADIONUCLIDE THERAPY | Lu-177-DOTATATE
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3. Full Text Opportunities for research in molecular radiotherapy
by Flux, Glenn D and O'Sullivan, Joe and Gaze, Mark N and Prise, Kevin M
British Journal of Radiology, ISSN 0007-1285, 2017, Volume 90, Issue 1071, p. 20160921
Cancer has been treated with radiopharmaceuticals for 80 years. A recent National Cancer Research Institute report from the Clinical and Translational... 
NEUROBLASTOMA | THERAPY | DOSIMETRY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Medical Oncology - methods | Biomedical Research - methods | Radiopharmaceuticals | Humans | Radiotherapy - methods
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4. Full Text A systematic review of (131) I-meta iodobenzylguanidine molecular radiotherapy for neuroblastoma
by Wilson, JS and Gains, JE and Moroz, V and Wheatley, K and Gaze, MN
EUROPEAN JOURNAL OF CANCER, ISSN 0959-8049, 03/2014, Volume 50, Issue 4, pp. 801 - 815
The optimal use and effectiveness of I-131-meta iodobenzylguanidine (I-131-mIBG) molecular radiotherapy for neuroblastoma remain unclear despite extensive... 
I-131 METAIODOBENZYLGUANIDINE | Molecular radiotherapy | Clinical effectiveness | REFRACTORY NEUROBLASTOMA | TARGETED RADIOTHERAPY | Systematic review | Neuroblastoma | MYELOABLATIVE CHEMOTHERAPY | CLINICAL-EXPERIENCE | Radionuclide | Radiopharmaceutical | IODINE-131-METAIODOBENZYLGUANIDINE THERAPY | INTERNATIONAL CRITERIA | ONCOLOGY | I-131-meta iodobenzylguanidine | HIGH-DOSE CHEMOTHERAPY | HIGH-RISK NEUROBLASTOMA | PHASE-I
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5. Full Text A systematic review of 131I-meta iodobenzylguanidine molecular radiotherapy for neuroblastoma
by Wilson, Jayne S and Gains, Jennifer E and Moroz, Veronica and Wheatley, Keith and Gaze, Mark N
European Journal of Cancer, ISSN 0959-8049, 03/2014, Volume 50, Issue 4, pp. 801 - 815
The optimal use and effectiveness of I-meta iodobenzylguanidine ( I-mIBG) molecular radiotherapy for neuroblastoma remain unclear despite extensive clinical... 
Molecular radiotherapy | 131I-meta iodobenzylguanidine | Radionuclide | Clinical effectiveness | Radiopharmaceutical | Systematic review | Neuroblastoma | I-meta iodobenzylguanidine | Radiotherapy Dosage | Iodine Radioisotopes - therapeutic use | Clinical Trials as Topic - statistics & numerical data | Humans | Neuroblastoma - radiotherapy | 3-Iodobenzylguanidine - therapeutic use | Neuroblastoma - epidemiology | Treatment Outcome | Research Design
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6. Advanced olfactory neuroblastoma treated with combined conventional and hypofractionated stereotactic radiotherapy
by Nomoto, Satoshi and Shioyama, Yoshiyuki and Ohga, Saiji and Nakamura, Katsumasa and Honda, Hiroshi
03/2011
Three patients with olfactory neuroblastoma (ONB) of the nasal and/or paranasal cavity were treated with a combination of conventional radiotherapy (RT) and... 
stereotactic radiotherapy | olfactory neuroblastoma | Cyberknife
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7. Full Text Usefulness of Renal Autotransplantation for Radiotherapy-induced Renovascular Hypertension
by Wakabayashi, Shinichi and Takaoka, Hiroyuki and Miyauchi, Hideaki and Sazuka, Tomokazu and Saito, Yuichi and Sugimoto, Kazumasa and Funabashi, Nobusada and Ichikawa, Tomohiko and Matsubara, Hisahiro and Kobayashi, Yoshio
Internal Medicine, ISSN 0918-2918, 2019, Volume 58, Issue 13, pp. 1897 - 1899
We experienced a young woman with congestive heart failure (CHF) caused by renovascular hypertension (RVH) and subsequent hypertensive heart disease. She... 
Neuroblastoma | Renal autotransplantation | Renovascular hypertension | Hypertensive heart disease | neuroblastoma | hypertensive heart disease | MEDICINE, GENERAL & INTERNAL | ARTERY STENOSIS | renovascular hypertension | renal autotransplantation | Hypertension | Radiation effects | Renal artery | Radiation | Stenosis | Cardiovascular disease | Radiation therapy | Congestive heart failure | Coronary artery disease | Blood pressure | Cardiovascular diseases | Heart diseases | Age | Case Report
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8. Full Text A retrospective multicenter study of carbon ion radiotherapy for locally advanced olfactory neuroblastomas
by Suefuji, Hiroaki and Koto, Masashi and Demizu, Yusuke and Saitoh, Jun-Ichi and Shioyama, Yoshiyuki and Tsuji, Hiroshi and Okimoto, Tomoaki and Ohno, Tatsuya and Nemoto, Kenji and Nakano, Takashi and Kamada, Tadashi
Anticancer Research, ISSN 0250-7005, 03/2018, Volume 38, Issue 3, pp. 1665 - 1670
The purpose was to evaluate efficacy and safety of carbon ion radiotherapy (C-ion RT) in patients with locally advanced olfactory neuroblastomas (ONBs). This... 
Cancer of the head | Neck | Radiotherapy | Multicenter study | Carbon ion radiotherapy | Olfactory neuroblastoma | SURGERY | METAANALYSIS | TOXICITY | carbon ion radiotherapy | IRRADIATION | THERAPY | ONCOLOGY | ESTHESIONEUROBLASTOMA | radiotherapy | multicenter study | EXPERIENCE | cancer of the head and neck | OUTCOMES
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9. EANM practical guidance on uncertainty analysis for molecular radiotherapy absorbed dose calculations
by Gear, Jonathan I and Cox, Maurice G and Gustafsson, Johan and Gleisner, Katarina Sjögreen and Murray, Iain and Glatting, Gerhard and Konijnenberg, Mark and Flux, Glenn D
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 12/2018, Volume 45, Issue 13, pp. 2456 - 2474
A framework is proposed for modelling the uncertainty in the measurement processes constituting the dosimetry chain that are involved in internal absorbed dose... 
Uncertainty analysis | Dosimetry | I-131 METAIODOBENZYLGUANIDINE | NEUROBLASTOMA | QUALITY-CONTROL | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | SPECT | SOFTWARE | Dosimeters | Chains | Mathematical models | Radiation therapy | Calibration | Recovery
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10. Full Text Targeted molecular radiotherapy of pediatric solid tumors using a radioiodinated alkyl-phospholipid ether analog
by Baiu, Dana C and Marsh, Ian R and Boruch, Alexander E and Shahi, Ankita and Bhattacharya, Saswati and Jeffery, Justin J and Zhao, Qianqian and Hall, Lance T and Weichert, Jamey P and Bednarz, Bryan P and Otto, Mario
Journal of Nuclear Medicine, ISSN 0161-5505, 02/2018, Volume 59, Issue 2, pp. 244 - 250
External-beam radiotherapy plays a critical role in the treatment of most pediatric solid tumors. Particularly in children, achieving an optimal therapeutic... 
MicroPET/CT imaging | Radionuclide therapy | Pediatric cancer | Targeted radiotherapy | SURVIVAL | microPET/CT imaging | targeted radiotherapy | NEUROBLASTOMA | MODEL | RADIATION | CHEMOTHERAPY | pediatric cancer | CHILDREN | radionuclide therapy | RHABDOMYOSARCOMA | MALIGNANCIES | EXPERIENCE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CT imaging | microPET | Theranostics
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11. Full Text Proton Radiotherapy for High-Risk Pediatric Neuroblastoma: Early Outcomes and Dose Comparison
by Hattangadi, Jona A., M.D and Rombi, Barbara, M.D and Yock, Torunn I., M.D and Broussard, George, B.S and Friedmann, Alison M., M.D and Huang, Mary, M.D and Chen, Yen-Lin E., M.D and Lu, Hsiao-Ming, Ph.D and Kooy, Hanne, Ph.D and MacDonald, Shannon M., M.D
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 83, Issue 3, pp. 1015 - 1022
Purpose To report the early outcomes for children with high-risk neuroblastoma treated with proton radiotherapy (RT) and to compare the dose distributions for... 
Radiology | Hematology, Oncology and Palliative Medicine | High-risk neuroblastoma | IMPT | Intensity-modulated radiotherapy | Proton radiotherapy | IMRT | Intensity-modulated proton radiotherapy | SURVIVAL | RADIATION-THERAPY | TRANSPLANTATION | IMPACT | ONCOLOGY | INFANTS | LOCAL-CONTROL | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | RESEARCH-HOSPITAL EXPERIENCE | Protons - adverse effects | Humans | Child, Preschool | Protons - therapeutic use | Infant | Male | Neuroblastoma - therapy | Organs at Risk | Radiotherapy, Intensity-Modulated - adverse effects | Neoplasm, Residual | Organ Sparing Treatments - methods | Female | Neuroblastoma - pathology | Radiotherapy Dosage | Neuroblastoma - genetics | Radiotherapy, Intensity-Modulated - methods | Induction Chemotherapy - methods | Neuroblastoma - diagnostic imaging | Treatment Outcome | Tumor Burden | Combined Modality Therapy - adverse effects | Photons - therapeutic use | Radiography | Neuroblastoma - radiotherapy | Radiotherapy, Conformal - adverse effects | Combined Modality Therapy - methods | Radiotherapy, Conformal - methods | Pediatrics | Neuroblastoma | Radiotherapy | Nuclear radiation | Analysis | Radiation | Adjuvants | SURGERY | PATIENTS | NEOPLASMS | FAILURES | LUNGS | ERYTHEMA | RADIATION DOSES | PROTONS | CHEMOTHERAPY | CHILDREN | HEART | KIDNEYS | RADIATION DOSE DISTRIBUTIONS | RADIOLOGY AND NUCLEAR MEDICINE | PEDIATRICS | STEM CELLS | RADIOTHERAPY | SKIN | SIDE EFFECTS | ANOREXIA | HAZARDS
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12. Full Text The role of TRAIL in fatigue induced by repeated stress from radiotherapy
by Feng, Li Rebekah, PhD and Suy, Simeng, PhD and Collins, Sean P., MD, PhD and Saligan, Leorey N., PhD, RN, CRNP, FAAN
Journal of Psychiatric Research, ISSN 0022-3956, 2017, Volume 91, pp. 130 - 138
Abstract Fatigue is one of the most common and debilitating side effects of cancer and cancer treatment, and yet its etiology remains elusive. The goal of this... 
Psychiatry | OXIDATIVE STRESS | SYMPTOM CLUSTER | CANCER-RELATED FATIGUE | FUNCTIONAL ASSESSMENT | PSYCHIATRY | PROSTATE-CANCER | DEPRESSION RATING-SCALE | QUALITY-OF-LIFE | IONIZING-RADIATION | NEURONAL DAMAGE | RADIATION-THERAPY | Tumor Necrosis Factor-alpha - metabolism | Reproducibility of Results | Enzyme-Linked Immunosorbent Assay | Humans | Fatigue - etiology | Male | Radiotherapy - adverse effects | TNF-Related Apoptosis-Inducing Ligand - metabolism | Young Adult | Psychiatric Status Rating Scales | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Analysis of Variance | Microarray Analysis | Adolescent | Cell Line, Tumor | Adult | Female | Neoplasms - radiotherapy | Surveys and Questionnaires | Neuroblastoma - pathology | Stress, Psychological - complications | Stress, Psychological - etiology | Cytokines - blood | Development and progression | Fatigue | Radiotherapy | Prostate cancer | Genomics | Research institutes
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13. Immunohistochemical evaluation of molecular radiotherapy target expression in neuroblastoma tissue
by Gains, Jennifer E and Sebire, Neil J and Moroz, Veronica and Wheatley, Keith and Gaze, Mark N
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 03/2018, Volume 45, Issue 3, pp. 402 - 411
Purpose Neuroblastoma may be treated with molecular radiotherapy, I-131 meta-Iodobenzylguanidine and Lu-177 Lutetium DOTATATE, directed at distinct molecular... 
Immunohistochemistry | Molecular radiotherapy | Meta-Iodobenzylguanidine | Somatostatin receptor | Lutetium DOTATATE | Noradrenalin transporter molecule | Neuroblastoma | NEUROENDOCRINE TUMORS | I-123 METAIODOBENZYLGUANIDINE | CELL-LINES | METAIODOBENZYLGUANIDINE UPTAKE | QUANTITATIVE-DETERMINATION | POLYMERASE-CHAIN-REACTION | GENE-EXPRESSION | CHILDHOOD NEUROBLASTOMA | SOMATOSTATIN RECEPTOR SCINTIGRAPHY | HIGH-RISK NEUROBLASTOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Correlation coefficient | Evaluation | Correlation coefficients | Data processing | Radiation therapy | Paraffin | Patients | Lutetium | Confidence intervals | Monoclonal antibodies | Sampling methods | Norepinephrine | Somatostatin | Noradrenaline | Transporter | Tumors
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14. Full Text The Evidence for External Beam Radiotherapy in High-Risk Neuroblastoma of Childhood: A Systematic Review
by Arumugam, S and Manning-Cork, N.J and Gains, J.E and Boterberg, T and Gaze, M.N
Clinical Oncology, ISSN 0936-6555, 03/2019, Volume 31, Issue 3, pp. 182 - 190
External beam radiotherapy is widely used in various ways in the management of neuroblastoma. Despite extensive clinical experience, the precise role of... 
neuroblastoma | radiotherapy | systematic review | radiation | High-risk | PEDIATRIC NEUROBLASTOMA | INTENSIVE CHEMOTHERAPY | EXCELLENT LOCAL-CONTROL | BONE-MARROW-TRANSPLANTATION | INTERNATIONAL SOCIETY | MODULATED RADIATION-THERAPY | ONCOLOGY | METASTATIC NEUROBLASTOMA | HIGH-DOSE CHEMOTHERAPY | MYELOABLATIVE THERAPY | QUALITY-ASSURANCE | Metastasis | Neuroblastoma | Radiotherapy | Radiation
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15. Full Text Radiotherapy for childhood cancer and subsequent thyroid cancer risk: a systematic review
by Lorenz, Eva and Scholz-Kreisel, Peter and Baaken, Dan and Pokora, Roman and Blettner, Maria
European Journal of Epidemiology, ISSN 0393-2990, 12/2018, Volume 33, Issue 12, pp. 1139 - 1162
Most of the pooled analyses and reviews reported an association between radiotherapy for childhood cancer and an increased thyroid cancer risk. Up to now this... 
Public Health | Medicine & Public Health | Haemangioma | Secondary thyroid cancer | Infectious Diseases | Oncology | Systematic review | Childhood cancer survivors | Radiation therapy | Cardiology | Epidemiology | ATOMIC-BOMB SURVIVORS | EXTERNAL RADIATION | NEUROBLASTOMA | 2ND MALIGNANT NEOPLASMS | RADIATION-THERAPY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HODGKINS-DISEASE | ACUTE LYMPHOBLASTIC-LEUKEMIA | POOLED ANALYSIS | EXPOSURE | MARROW TRANSPLANTATION | Humans | Neoplasms, Radiation-Induced - etiology | Thyroid Neoplasms - epidemiology | Thyroid Neoplasms - etiology | Neoplasms - radiotherapy | Neoplasms, Radiation-Induced - epidemiology | Child | Thyroid cancer | Oncology, Experimental | Radiation | Research | Radiotherapy | Risk factors | Cancer in children | Cancer | Radiation effects | Health risks | Risk | Literature reviews | Studies | Heterogeneity | Reviews | Children | Health risk assessment | Thyroid
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16. Full Text Abdominal Radiotherapy: A Major Determinant of Metabolic Syndrome in Nephroblastoma and Neuroblastoma Survivors
by Waas, Marjolein and Neggers, Bas and Raat, Hein and Rij, Caroline and Pieters, Rob and Heuvel-Eibrink, Marry
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52237
textabstractBackground: Reports on metabolic syndrome in nephroblastoma and neuroblastoma survivors are scarce. Aim was to evaluate the occurrence of and the... 
ADULT SURVIVORS | LONG-TERM SURVIVORS | CHILDHOOD-CANCER | OBESITY | RISK-FACTORS | CELL FUNCTION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | BODY-COMPOSITION | GLUCOSE-TOLERANCE | ADIPOSE-TISSUE | Metabolic Syndrome - etiology | Prospective Studies | Follow-Up Studies | Wilms Tumor - radiotherapy | Humans | Middle Aged | Neuroblastoma - blood | Child, Preschool | Infant | Male | Kidney Neoplasms - metabolism | Radiotherapy - adverse effects | Wilms Tumor - blood | Case-Control Studies | Kidney Neoplasms - blood | Young Adult | Metabolic Syndrome - blood | Dyslipidemias - blood | Hip - physiology | Fasting - blood | Insulin Resistance - physiology | Radiography, Abdominal - methods | Adult | Cholesterol, LDL - blood | Fatty Acids, Nonesterified - blood | Female | Blood Pressure - physiology | Wilms Tumor - metabolism | Child | Infant, Newborn | Body Mass Index | Cross-Sectional Studies | Survivors | Kidney Neoplasms - radiotherapy | Abdomen - radiation effects | Radiation Injuries - etiology | Abdominal Fat - metabolism | Waist Circumference - physiology | Neuroblastoma - radiotherapy | Radiation Injuries - blood | Adolescent | Triglycerides - blood | Cholesterol, HDL - blood | Dyslipidemias - metabolism | Adiposity - physiology | Neuroblastoma - metabolism | Blood Glucose - metabolism | Dyslipidemias - physiopathology | Type 2 diabetes | Low density lipoproteins | Radiation | Development and progression | Triglycerides | Neuroblastoma | Radiotherapy | Fatty acids | Cholesterol | Blood | Analysis and chemistry | Physiological aspects | Nephroblastoma | Lipoproteins (low density) | Adipose tissue | Circumferences | Irradiated | Body composition | Body composition (biology) | Blood pressure | Lipoproteins (high density) | Dual energy X-ray absorptiometry | Mortality | Energy measurement | Metabolic diseases | Radiation therapy | Insulin | Hip | Abdomen | Irradiation | Insulin resistance | Females | Health risk assessment | Metabolic disorders
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17. Full Text Utility of adjuvant chemotherapy in patients receiving surgery and adjuvant radiotherapy for primary treatment of esthesioneuroblastoma
by Miller, Kevin C and Marinelli, John P and Van Gompel, Jamie J and Link, Michael J and Janus, Jeffrey R and Foote, Robert L and Price, Katharine A and Garcia, Joaquin and Rivera, Michael and Chintakuntlawar, Ashish V
Head & Neck, ISSN 1043-3074, 05/2019, Volume 41, Issue 5, pp. 1335 - 1341
Background Past research established that surgery plus adjuvant radiotherapy (S + AR) improves overall survival (OS) in esthesioneuroblastoma (ENB). However,... 
olfactory neuroblastoma | adjuvant | chemotherapy | esthesioneuroblastoma | survival | SURGERY | PROGNOSIS | ADOLESCENT | CELL LUNG-CANCER | ETOPOSIDE | CISPLATIN | OTORHINOLARYNGOLOGY | EXPERIENCE | Medical research | Care and treatment | Surgery | Analysis | Adjuvant treatment | Etoposide | Medicine, Experimental | Medical records | Metastasis | Radiotherapy | Cancer | Chemotherapy | Platinum | Radiation therapy | Neuroblastoma | Olfactory epithelium | Survival | Patients
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18. Full Text Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-cis-Retinoic Acid
by Matthay, Katherine K and Villablanca, Judith G and Seeger, Robert C and Stram, Daniel O and Harris, Richard E and Ramsay, Norma K and Swift, Patrick and Shimada, Hiroyuki and Black, C. Thomas and Brodeur, Garrett M and Gerbing, Robert B and Reynolds, C. Patrick and Childrens Canc Grp
The New England Journal of Medicine, ISSN 0028-4793, 10/1999, Volume 341, Issue 16, pp. 1165 - 1173
Neuroblastoma, the most common extracranial solid tumor of childhood, has a long-term survival rate of only 15 percent. 1 At diagnosis the defining... 
TOTAL-BODY IRRADIATION | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | INTERNATIONAL CRITERIA | RETINOIC ACID | N-MYC | METASTATIC NEUROBLASTOMA | CHILDRENS-CANCER-GROUP | MYELOABLATIVE THERAPY | PROGNOSTIC VALUE | NEURO-BLASTOMA CELLS | Bone marrow | Care and treatment | Transplantation | Neuroblastoma | Cytotoxicity | Chemotherapy | Transplants & implants | Acids | Tumors
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