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1. Full Text Metabolite profiling of Alzheimer's disease cerebrospinal fluid
by Czech, Christian and Berndt, Peter and Busch, Kristina and Schmitz, Oliver and Wiemer, Jan and Most, Veronique and Hampel, Harald and Kastler, Jürgen and Senn, Hans
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31501
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive loss of cognitive functions. Today the diagnosis of AD relies on clinical... 
SENILE DEMENTIA | BIOMARKERS | HOMOCYSTEINE | NOREPINEPHRINE | MULTIDISCIPLINARY SCIENCES | CSF | MARKERS | DYSFUNCTION | DIAGNOSTICS | DISCOVERY | CORTISOL | Alzheimer Disease - diagnosis | Gas Chromatography-Mass Spectrometry | Hydrocortisone - cerebrospinal fluid | Humans | Sensitivity and Specificity | Alzheimer Disease - metabolism | Metabolome | Cysteine - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Case-Control Studies | Disease Progression | Uridine - cerebrospinal fluid | Medical research | Advertising executives | Cysteine | Corticosteroids | Metabolites | Medicine, Experimental | Liquid chromatography | Mass spectrometry | Alzheimer's disease | Cystine | Plasma | Nuclear magnetic resonance--NMR | Profiling | Neuropathology | Cognitive ability | Clinical trials | Amino acids | Statistical methods | Cerebrospinal fluid | Hormones | Hydrocortisone | Proteins | Aging | Age | Statistical analysis | Neurodegenerative diseases | Mass spectroscopy | Metabolism | Patients | Chromatography | Sensitivity | Uridine | Biomarkers | Scientific imaging | Alzheimers disease | Homocysteine | Psychiatry | Pharmaceuticals | Dementia | Nuclear magnetic resonance | NMR
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2. Full Text Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
by Toledo, J.B and Zetterberg, H and van Harten, A.C and Glodzik, L and Martinez-Lage, P and Bocchio-Chiavetto, L and Rami, L and Hansson, O and Sperling, R and Engelborghs, S and Osorio, R.S and Vanderstichele, H and Vandijck, M and Hampel, H and Teipl, S and Moghekar, A and Albert, M and Hu, W.T and Argiles, J.A.M and Gorostidi, A and Teunissen, C.E and de Deyn, P.P and Hyman, B.T and Molinuevo, J.L and Frisoni, G. B and Linazasoro, G and de Leon, M.J and van der Flier, W.M and Scheltens, P and Blennow, K and Shaw, L.M and Trojanowski, J.Q and Alzheimer's Dis Neuroimaging and Alzheimer’s Disease Neuroimaging Initiative and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Brain, ISSN 0006-8950, 2015, Volume 138, Issue 9, pp. 2701 - 2715
In a large multicentre study, Toledo et al. examine core Alzheimer's disease CSF biomarkers in 1233 cognitively normal subjects aged 40-85 years. Alzheimer... 
dementia | cognitive ageing | Alzheimer's disease | imaging | biomarkers | ADULT LIFE-SPAN | ASSOCIATION GUIDELINES | CSF BIOMARKERS | 2 ANALYTICAL PLATFORMS | NEUROSCIENCES | CLINICAL NEUROLOGY | NEUROPATHOLOGIC ASSESSMENT | TAU PROTEINS | NATIONAL INSTITUTE | BETA-AMYLOID 1-42 | AGING BRAIN | AGE | Severity of Illness Index | Alzheimer Disease - physiopathology | Peptide Fragments - cerebrospinal fluid | Age Factors | Neurodegenerative Diseases - etiology | Humans | Middle Aged | Male | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Neuropsychological Tests | Analysis of Variance | Apolipoproteins E - genetics | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Cognition - physiology | Adult | Female | Aged | Alzheimer Disease - genetics | Cohort Studies | Neurosciences | Neurovetenskaper
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3. Full Text Alzheimer's disease cerebrospinal fluid biomarkers predict cognitive decline in lewy body dementia
by Abdelnour, Carla and van Steenoven, Inger and Londos, Elisabet and Blanc, Frederic and Auestad, Bjorn and Kramberger, Milica G and Zetterberg, Henrik and Mollenhauer, Brit and Boada, Merce and Aarsland, Dag and European DLB Consortium and on behalf of the European DLB Consortium and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Movement Disorders, ISSN 0885-3185, 08/2016, Volume 31, Issue 8, pp. 1203 - 1208
ABSTRACT Introduction Alzheimer's disease pathologies are common in dementia with Lewy bodies, but their clinical relevance is not clear. CSF biomarkers... 
CSF biomarkers | cognitive decline | Lewy body dementia | TAU-PROTEIN | MINI-MENTAL-STATE | DIFFERENTIAL-DIAGNOSIS | CSF AMYLOID-BETA | PERFORMANCE | ALPHA-SYNUCLEIN | PATHOLOGY | CLINICAL NEUROLOGY | A-BETA | BODIES | PARKINSONS-DISEASE | Alzheimer Disease - physiopathology | Peptide Fragments - cerebrospinal fluid | Prognosis | Follow-Up Studies | Humans | Male | Mental Status and Dementia Tests | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Disease Progression | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Biomarkers | Female | Lewy Body Disease - cerebrospinal fluid | Aged | Lewy Body Disease - physiopathology | Medicine, Experimental | Medical research | Biological markers | Alzheimer's disease | Analysis | Parkinson's disease | Threonine | Neurodegenerative diseases | Cognitive ability | Cerebrospinal fluid | Lewy bodies | Tau protein | Vitamin E | Dementia disorders | β-Amyloid | Alzheimers disease | Movement disorders | Dementia | Neurosciences | pathology | mini-mental-state | bodies | csf amyloid-beta | parkinsons-disease | Neurosciences & Neurology | alpha-synuclein | a-beta | performance | differential-diagnosis | tau-protein | Neurovetenskaper
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4. Full Text Dual-Task Performance and Neurodegeneration: Correlations Between Timed Up-and-Go Dual-Task Test Outcomes and Alzheimer’s Disease Cerebrospinal Fluid Biomarkers
by Åhman, Hanna Bozkurt and Giedraitis, Vilmantas and Cedervall, Ylva and Lennhed, Björn and Berglund, Lars and McKee, Kevin and Kilander, Lena and Rosendahl, Erik and Ingelsson, Martin and Åberg, Anna Cristina and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Socialt arbete and Medicinsk vetenskap
Journal of Alzheimer's Disease, ISSN 1387-2877, 09/2019, Volume 71, Issue s1, pp. S75 - S83
Background: Tools to identify individuals at preclinical stages of dementia disorders are needed to enable early interventions. Alterations in dual-task... 
Neurodegenerative diseases | Cognitive ability | Disorders | Impairment | Cerebrospinal fluid | Tau protein | Neurodegeneration | Correlation analysis | Dementia disorders | Biomarkers | Longitudinal studies | Alzheimer's disease | Enzyme-linked immunosorbent assay | Dementia | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
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5. Full Text Reproducibility of Alzheimer’s Disease Cerebrospinal Fluid-Biomarker Measurements under Clinical Routine Conditions
by Vogelgsang, Jonathan and Wedekind, Dirk and Bouter, Caroline and Klafki, Hans-W and Wiltfang, Jens
Journal of Alzheimer's Disease, ISSN 1387-2877, 02/2018, Volume 62, Issue 1, pp. 203 - 212
Analysis of cerebrospinal fluid (CSF) is one of the key tools for the state-of-the-art differential diagnosis of dementias. Dementia due to Alzheimer’s disease... 
Neurodegenerative diseases | Tau protein | Laboratories | Reproducibility | Dementia disorders | Biomarkers | Amyloid | Differential diagnosis | Diagnostic systems | Cerebrospinal fluid | Alzheimer's disease
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6. Full Text Memory Correlates of Alzheimer’s Disease Cerebrospinal Fluid Markers: A Longitudinal Cohort Study
by Reijs, Babette L.R and Ramakers, Inez H.G.B and Köhler, Sebastian and Teunissen, Charlotte E and Koel-Simmelink, Marleen and Nathan, Pradeep J and Tsolaki, Magda and Wahlund, Lars-Olof and Waldemar, Gunhild and Hausner, Lucrezia and Vandenberghe, Rik and Johannsen, Peter and Blackwell, Andrew and Vanderstichele, Hugo and Verhey, Frans and Visser, Pieter Jelle
Journal of Alzheimer's Disease, ISSN 1387-2877, 10/2017, Volume 60, Issue 3, pp. 1119 - 1128
Background: Performance on episodic, semantic, and working memory tests is impaired in Alzheimer’s disease (AD)-type dementia, but it is unclear which type of... 
Neurodegenerative diseases | Memory | Spatial discrimination learning | Cognitive ability | Spatial discrimination | Mental task performance | Cognition | Cerebrospinal fluid | Learning | Memory tasks | Tau protein | Semantics | Dementia disorders | Biomarkers | Recall | Short term memory | Alzheimer's disease | Spatial memory | Dementia
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7. Full Text Applying fluid biomarkers to Alzheimer's disease
by Zetterberg, Henrik and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
American journal of physiology. Cell physiology, ISSN 0363-6143, 07/2017, Volume 313, Issue 1, pp. C3 - C10
Alzheimer's disease (AD) is a common neurodegenerative disease that starts with a clinically silent phase of a decade or more during which brain pathologies... 
Diagnosis, Differential | Peptide Fragments - cerebrospinal fluid | Humans | Neurodegenerative Diseases - diagnosis | Fatty Acid-Binding Proteins - cerebrospinal fluid | Neurodegenerative Diseases - blood | tau Proteins - cerebrospinal fluid | Biomarkers - blood | Alzheimer Disease - cerebrospinal fluid | Intermediate Filaments - metabolism | Neurodegenerative Diseases - cerebrospinal fluid | Alzheimer Disease - diagnosis | Amyloid beta-Peptides - cerebrospinal fluid | Neurocalcin - cerebrospinal fluid | Neurogranin - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Alzheimer Disease - blood | Occludin - blood | Physiological aspects | Body fluids | Biological markers | Alzheimer's disease | amyloid | Alzheimer’s disease | neurofilament | biomarkers | cerebrospinal fluid | Theme | tau | plasma | serum | blood | neurogranin | Neurodegenerative Diseases/blood/cerebrospinal fluid/diagnosis | Biomarkers/blood/cerebrospinal fluid | tau Proteins/cerebrospinal fluid | Neurogranin/cerebrospinal fluid | Occludin/blood | Diagnosis | Neurocalcin/cerebrospinal fluid | Neurologi | Differential | Peptide Fragments/cerebrospinal fluid | Amyloid beta-Peptides/cerebrospinal fluid | Fatty Acid-Binding Proteins/cerebrospinal fluid | Neurology | Intermediate Filaments/metabolism | Alzheimer Disease/blood/cerebrospinal fluid/diagnosis
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8. Full Text α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
by Mollenhauer, Brit, Dr and Locascio, Joseph J, PhD and Schulz-Schaeffer, Walter, MD and Sixel-Döring, Friederike, MD and Trenkwalder, Claudia, MD and Schlossmacher, Michael G, Dr
Lancet Neurology, The, ISSN 1474-4422, 2011, Volume 10, Issue 3, pp. 230 - 240
Summary Background Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy are brain disorders characterised by intracellular α-synuclein... 
Neurology | BIOMARKERS | MULTIPLE SYSTEM ATROPHY | DEMENTIA | RESEARCH CRITERIA | TASK-FORCE | ALZHEIMERS-DISEASE | CLINICAL-DIAGNOSIS | QUANTIFICATION | CSF | LEWY BODIES | CLINICAL NEUROLOGY | Cross-Sectional Studies | Lewy Body Disease - diagnosis | Humans | Middle Aged | Male | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Alzheimer Disease - diagnosis | Multiple System Atrophy - cerebrospinal fluid | alpha-Synuclein - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Aged, 80 and over | Parkinson Disease - diagnosis | Adult | Female | Lewy Body Disease - cerebrospinal fluid | Aged | Biomarkers - cerebrospinal fluid | Multiple System Atrophy - diagnosis | Cohort Studies | Brain | Basal ganglia | Deposits | Parkinson's disease | Hydrocephalus | Neurodegenerative diseases | biomarkers | Central nervous system diseases | Clinical trials | Cerebrospinal fluid | Synuclein | Statistics | Lewy bodies | Atrophy | Neurological diseases | Hospitals | Tau protein | Dementia disorders | Alzheimer's disease | Age | Enzyme-linked immunosorbent assay | Movement disorders | progressive supranuclear palsy
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9. Full Text Genetic Loci Associated with Alzheimer's Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort
by Elias-Sonnenschein, Lyzel S and Helisalmi, Seppo and Natunen, Teemu and Hall, Anette and Paajanen, Teemu and Herukka, Sanna-Kaisa and Laitinen, Marjo and Remes, Anne M and Koivisto, Anne M and Mattila, Kari M and Lehtimaki, Terho and Verhey, Frans R. J and Visser, Pieter Jelle and Soininen, Hilkka and Hiltunen, Mikko
PLOS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e59676
Objectives: To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of... 
COMMON VARIANTS | POLYMORPHISMS | PROTEIN | MULTIDISCIPLINARY SCIENCES | A-BETA | RISK | SORL1 | BINDING | TAU LEVELS | GENOME-WIDE ASSOCIATION | APOLIPOPROTEIN-E | Genetic Predisposition to Disease | Genome-Wide Association Study | Phosphorylation | Apolipoprotein E4 - genetics | Clusterin - genetics | Peptide Fragments - cerebrospinal fluid | Membrane Proteins - genetics | Humans | Middle Aged | Risk Factors | Logistic Models | Male | tau Proteins - cerebrospinal fluid | Genetic Loci | Alzheimer Disease - cerebrospinal fluid | Case-Control Studies | Finland | Amyloid beta-Peptides - cerebrospinal fluid | Female | Aged | Polymorphism, Single Nucleotide | Protein Processing, Post-Translational | Biomarkers - cerebrospinal fluid | Alzheimer Disease - genetics | Development and progression | Genetic aspects | Single nucleotide polymorphisms | Cerebrospinal fluid | Health aspects | Alzheimer's disease | Risk factors | Tau proteins
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10. Full Text A Luminex Assay Detects Amyloid β Oligomers in Alzheimer’s Disease Cerebrospinal Fluid
by Herskovits, Adrianna Z and Locascio, Joseph J and Peskind, Elaine R and Li, Ge and Hyman, Bradley T
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e67898
Amyloid beta (aβ) protein assembles into larger protein aggregates during the pathogenesis of Alzheimer’s disease (AD) and there is increasing evidence that... 
Peptides | Neuropathology | Pathogenesis | Memory | Cerebrospinal fluid | Assaying | Proteins | Oligomers | Alzheimer's disease | Enzyme-linked immunosorbent assay | Sensitivity analysis | Medical imaging | Oligomerization | Neurodegenerative diseases | Fluid | Behavioral sciences | Patients | Neurology | Brain research | Hospitals | Tau protein | Biomarkers | Diagnostic systems | Psychiatry | Dementia
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11. Full Text High performance plasma amyloid-β biomarkers for Alzheimer's disease
by Nakamura, Akinori and Kaneko, Naoki and Villemagne, Victor L and Kato, Takashi and Doecke, James and Doré, Vincent and Fowler, Chris and Li, Qiao-Xin and Martins, Ralph and Rowe, Christopher and Tomita, Taisuke and Matsuzaki, Katsumi and Ishii, Kenji and Ishii, Kazunari and Arahata, Yutaka and Iwamoto, Shinichi and Ito, Kengo and Tanaka, Koichi and Masters, Colin L and Yanagisawa, Katsuhiko
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7691, pp. 249 - 254
To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are expected to be most efficacious at the earliest and mildest... 
NATIONAL INSTITUTE | LIFE-STYLE AIBL | ANALYTICAL PLATFORMS | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | BLOOD-BASED BIOMARKERS | DIAGNOSTIC GUIDELINES | MILD COGNITIVE IMPAIRMENT | CEREBROSPINAL-FLUID | MASS-SPECTROMETRY | ASSOCIATION WORKGROUPS | Immunoprecipitation | Humans | Male | Positron-Emission Tomography | Amyloid beta-Peptides - blood | Case-Control Studies | Alzheimer Disease - diagnosis | Brain - metabolism | Mass Spectrometry | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Peptide Fragments - blood | Amyloid beta-Peptides - cerebrospinal fluid | Amyloid beta-Protein Precursor - blood | Female | Biomarkers - metabolism | Peptide Fragments - metabolism | Reproducibility of Results | Peptide Fragments - cerebrospinal fluid | Cognitive Dysfunction - metabolism | Japan | Cognitive Dysfunction - blood | Biomarkers - blood | Alzheimer Disease - cerebrospinal fluid | Cost-Benefit Analysis | Alzheimer Disease - metabolism | Aged | Biomarkers - cerebrospinal fluid | Australia | Alzheimer Disease - blood | Neuroimaging | Plasma | Brain | Peptides | Cognitive ability | Clinical trials | Cerebrospinal fluid | Blood | Aging | Alzheimer's disease | Medical research | Medical imaging | Neurodegenerative diseases | Positron emission | Mass spectroscopy | Amyloid precursor protein | Studies | Biomarkers | Ligands | Scientific imaging | Alzheimers disease | Mass spectrometry | Positron emission tomography | Dementia
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12. Full Text Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
by Shaw, Leslie M and Vanderstichele, Hugo and Knapik‐Czajka, Malgorzata and Clark, Christopher M and Aisen, Paul S and Petersen, Ronald C and Blennow, Kaj and Soares, Holly and Simon, Adam and Lewczuk, Piotr and Dean, Robert and Siemers, Eric and Potter, William and Lee, Virginia M.‐Y and Trojanowski, John Q and Alzheimer's Dis Neuroimaging Initi and Alzheimer's Disease Neuroimaging Initiative and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Annals of Neurology, ISSN 0364-5134, 04/2009, Volume 65, Issue 4, pp. 403 - 413
Objective Develop a cerebrospinal fluid biomarker signature for mild Alzheimer's disease (AD) in Alzheimer's Disease Neuroimaging Initiative (ADNI) subjects.... 
DIAGNOSIS | TRIALS | PROFILE | FRONTOTEMPORAL DEMENTIA | MARKERS | CSF BIOMARKERS | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | TAU LEVELS | CLINICAL NEUROLOGY | DECLINE | Phosphorylation | Apolipoprotein E4 - genetics | Area Under Curve | Humans | Middle Aged | Male | Threonine - metabolism | tau Proteins - chemistry | Alzheimer Disease - pathology | Sensitivity and Specificity | Statistics, Nonparametric | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Female | Retrospective Studies | Cognition Disorders - cerebrospinal fluid | Peptide Fragments - cerebrospinal fluid | Cognition Disorders - pathology | Cognition Disorders - genetics | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Disease Progression | Diagnostic Imaging | ROC Curve | Aged | Biomarkers - cerebrospinal fluid | Alzheimer Disease - genetics | Cohort Studies | Neuroimaging | Neurodegenerative diseases | Threonine | biomarkers | Cognitive ability | Data processing | Cerebrospinal fluid | Regression analysis | Tau protein | Autopsy | Alzheimer's disease | Immunoassays | Geriatrics | Peptide Fragments | pathology | Biological Markers | MEDICIN OCH HÄLSOVETENSKAP | tau Proteins | 80 and over | genetics | MEDICAL AND HEALTH SCIENCES | chemistry | Apolipoprotein E4 | Alzheimer Disease | Statistics | Amyloid beta-Protein | Nonparametric | Cognition Disorders | cerebrospinal fluid | metabolism
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