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1. Full Text Applying fluid biomarkers to Alzheimer’s disease
by Zetterberg, Henrik and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 2017, Volume 313, Issue 1, pp. C3 - C10
Plasma | Neurofilament | Alzheimer’s disease | Neurogranin | Biomarkers | Serum | Tau | Amyloid | Cerebrospinal fluid | Blood | Diagnosis, Differential | Peptide Fragments - cerebrospinal fluid | Humans | Neurodegenerative Diseases - diagnosis | Fatty Acid-Binding Proteins - cerebrospinal fluid | Neurodegenerative Diseases - blood | tau Proteins - cerebrospinal fluid | Biomarkers - blood | Alzheimer Disease - cerebrospinal fluid | Intermediate Filaments - metabolism | Neurodegenerative Diseases - cerebrospinal fluid | Alzheimer Disease - diagnosis | Amyloid beta-Peptides - cerebrospinal fluid | Neurocalcin - cerebrospinal fluid | Neurogranin - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Alzheimer Disease - blood | Occludin - blood | Physiological aspects | Body fluids | Biological markers | Alzheimer's disease | Temporal lobe | Neurodegenerative diseases | Parenchyma | Lewy bodies | Studies | Pathology | Fluids | Senile plaques | Tau protein | Neurodegeneration | Alzheimers disease | Plaques | Index Medicus | amyloid | neurofilament | biomarkers | cerebrospinal fluid | Theme | tau | plasma | serum | blood | neurogranin | amyloid beta protein | Data- och informationsvetenskap | Neurosciences | Fatty Acid-Binding Proteins | Peptide Fragments | Alzheimer disease | fatty acid binding protein | neurocalcin | tau Proteins | Intermediate Filaments | VSNL1 protein | Amyloid beta-Peptides | MAPT protein | peptide fragment | NRGN protein | Diagnosis | human | Neurovetenskaper | Neurodegenerative Diseases | differential diagnosis | amyloid beta-protein (1-42) | Differential | occludin | intermediate filament | biological marker | Computer and Information Science | OCLN protein | metabolism | tau protein | Neurodegenerative Diseases/blood/cerebrospinal fluid/diagnosis | Biomarkers/blood/cerebrospinal fluid | tau Proteins/cerebrospinal fluid | Neurogranin/cerebrospinal fluid | Occludin/blood | Neurocalcin/cerebrospinal fluid | Neurologi | Peptide Fragments/cerebrospinal fluid | Amyloid beta-Peptides/cerebrospinal fluid | Fatty Acid-Binding Proteins/cerebrospinal fluid | Neurology | Intermediate Filaments/metabolism | Alzheimer Disease/blood/cerebrospinal fluid/diagnosis
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2. Association of Cerebrospinal Fluid Neurofilament Light Protein Levels with Cognition in Patients with Dementia, Motor Neuron Disease, and Movement Disorders
by Olsson, Bob and Portelius, Erik and Cullen, Nicholas C and Sandelius, Åsa and Zetterberg, Henrik and Andreasson, Ulf and Höglund, Kina and Irwin, David J and Grossman, Murray and Weintraub, Daniel and Chen-Plotkin, Alice and Wolk, David and McCluskey, Leo and Elman, Lauren and Shaw, Leslie M and Toledo, Jon B and McBride, Jennifer and Hernandez-Con, Pilar and Lee, Virginia M-Y and Trojanowski, John Q and Blennow, Kaj
JAMA neurology, ISSN 2168-6149, 03/2019, Volume 76, Issue 3, pp. 318 - 325
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Frontotemporal Dementia - cerebrospinal fluid | Parkinsonian Disorders - cerebrospinal fluid | Humans | Middle Aged | Parkinsonian Disorders - diagnosis | Dementia - diagnosis | Male | Intermediate Filaments - metabolism | Case-Control Studies | Alzheimer Disease - diagnosis | Neurofilament Proteins - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Cognition - physiology | Dementia - cerebrospinal fluid | Female | Cognitive Dysfunction - diagnosis | tau Proteins - cerebrospinal fluid | Cognitive Dysfunction - cerebrospinal fluid | Motor Neuron Disease - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Frontotemporal Dementia - diagnosis | Parkinson Disease - diagnosis | Aged | Biomarkers - cerebrospinal fluid | Motor Neuron Disease - diagnosis | Brain | Parkinson's disease | Cognitive ability | Disorders | Impairment | Cognition | Cerebrospinal fluid | Proteins | Motor neuron diseases | Autopsy | Neurodegeneration | Dementia disorders | Degeneration | Paralysis | Light levels | Alzheimer's disease | Movement disorders | Autopsies | Neurodegenerative diseases | Motor neurone disease | Amyotrophic lateral sclerosis | Disease control | Lewy bodies | Diseases | Neurological diseases | Cognition & reasoning | Tau protein | Progressive supranuclear palsy | Correlation analysis | β-Amyloid | Frontotemporal dementia | Dementia
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3. Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis
by Bridel, Claire and Van Wieringen, Wessel N and Zetterberg, Henrik and Tijms, Betty M and Teunissen, Charlotte E and Alvarez-Cermeño, José C and Andreasson, Ulf and Axelsson, Markus and Bäckström, David C and Bartos, Ales and Bjerke, Maria and Blennow, Kaj and Boxer, Adam and Brundin, Lou and Burman, Joachim and Christensen, Tove and Fialová, Lenká and Forsgren, Lars and Frederiksen, Jette L and Gisslén, Magnus and Gray, Elizabeth and Gunnarsson, Martin and Hall, Sara and Hansson, Oskar and Herbert, Megan K and Jakobsson, Joel and Jessen-Krut, Jan and Janelidze, Shorena and Johannsson, Gudmundur and Jonsson, Michael and Kappos, Ludwig and Khademi, Mohsen and Khalil, Michael and Kuhle, Jens and Landén, Mikael and Leinonen, Ville and Logroscino, Giancarlo and Lu, Ching-Hua and Lycke, Jan and Magdalinou, Nadia K and Malaspina, Andrea and Mattsson, Niklas and Meeter, Lieke H and Mehta, Sanjay R and Modvig, Signe and Olsson, Tomas and Paterson, Ross W and Pérez-Santiago, Josué and Piehl, Fredrik and Pijnenburg, Yolande A. L and Pyykkö, Okko T and Ragnarsson, Oskar and Rojas, Julio C and Romme Christensen, Jeppe and Sandberg, Linda and Scherling, Carole S and Schott, Jonathan M and Sellebjerg, Finn T and Simone, Isabella L and Skillbäck, Tobias and Stilund, Morten and Sundström, Peter and Svenningsson, Anders and Tortelli, Rosanna and Tortorella, Carla and Trentini, Alessandro and Troiano, Maria and Turner, Martin R and Van Swieten, John C and Vågberg, Mattias and Verbeek, Marcel M and Villar, Luisa M and Visser, Pieter Jelle and Wallin, Anders and Weiss, Andreas and Wikkelsø, Carsten and Wild, Edward J and NFL Grp
JAMA neurology, ISSN 2168-6149, 2019, Volume 76, Issue 9, pp. 1035 - 1048
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunoassay | Multiple sclerosis | Sexually transmitted diseases--STD | Parkinson's disease | Central nervous system | Parkinsons disease | Disorders | Sex | Systematic review | Cerebrospinal fluid | Inflammatory diseases | Proteins | Human immunodeficiency virus--HIV | Dementia disorders | Diagnosis | Alzheimer's disease | Age | Movement disorders | Level (quantity) | Neurodegenerative diseases | Amyotrophic lateral sclerosis | Reporting | Age factors | Neurological diseases | Neurology | Men | Biomarkers | Diagnostic systems | Frontotemporal dementia | Dementia
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4. Full Text α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
by Mollenhauer, Brit, Dr and Locascio, Joseph J, PhD and Schulz-Schaeffer, Walter, MD and Sixel-Döring, Friederike, MD and Trenkwalder, Claudia, MD and Schlossmacher, Michael G, Dr
Lancet neurology, ISSN 1474-4422, 2011, Volume 10, Issue 3, pp. 230 - 240
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cross-Sectional Studies | Lewy Body Disease - diagnosis | Humans | Middle Aged | Male | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Alzheimer Disease - diagnosis | Multiple System Atrophy - cerebrospinal fluid | alpha-Synuclein - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Aged, 80 and over | Parkinson Disease - diagnosis | Adult | Female | Lewy Body Disease - cerebrospinal fluid | Aged | Biomarkers - cerebrospinal fluid | Multiple System Atrophy - diagnosis | Cohort Studies | Index Medicus | Brain | Basal ganglia | Deposits | Parkinson's disease | Hydrocephalus | Neurodegenerative diseases | biomarkers | Central nervous system diseases | Clinical trials | Cerebrospinal fluid | Synuclein | Statistics | Lewy bodies | Atrophy | Neurological diseases | Hospitals | Tau protein | Dementia disorders | Alzheimer's disease | Age | Enzyme-linked immunosorbent assay | Movement disorders | progressive supranuclear palsy
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5. Full Text Longitudinal analyses of cerebrospinal fluid α‐Synuclein in prodromal and early Parkinson's disease
by Mollenhauer, Brit and Caspell‐Garcia, Chelsea J and Coffey, Christopher S and Taylor, Peggy and Singleton, Andy and Shaw, Leslie M and Trojanowski, John Q and Frasier, Mark and Simuni, Tanya and Iranzo, Alex and Oertel, Wolfgang and Siderowf, Andrew and Weintraub, Daniel and Seibyl, John and Toga, Arthur W and Tanner, Caroline M and Kieburtz, Karl and Chahine, Lana M and Marek, Kenneth and Galasko, Douglas and PPMI Study and PPMI study and for the PPMI study
Movement disorders, ISSN 0885-3185, 09/2019, Volume 34, Issue 9, pp. 1354 - 1364
cohort studies | outcome research | Parkinson's disease/parkinsonism | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuroimaging | Metabolomics | Parkinson's disease | Dopamine | Neurodegenerative diseases | Secretion | Parkinsons disease | Cognitive ability | Sleep (REM) | Cerebrospinal fluid | Synuclein | Sleep disorders | Neurodegeneration | Proteomics | Hemoglobin | Biomarkers | Dopamine transporter | Age | Movement disorders | Dopamine receptors | Index Medicus | parkinsonism | Parkinson’s disease
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6. Full Text Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease
by Tokuda, Takahiko and Salem, Sultan A and Allsop, David and Mizuno, Toshiki and Nakagawa, Masanori and Qureshi, Mohamed M and Locascio, Joseph J and Schlossmacher, Michael G and El-Agnaf, Omar M.A
Biochemical and biophysical research communications, ISSN 0006-291X, 2006, Volume 349, Issue 1, pp. 162 - 166
α-Synuclein | Biomarker | Neurodegenerative diseases | Parkinson disease | Cerebrospinal fluid | Diagnosis | ELISA | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Humans | Middle Aged | Gene Expression Regulation | Male | Case-Control Studies | alpha-Synuclein - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Adolescent | Sex Factors | Aged, 80 and over | Aging | Parkinson Disease - diagnosis | Adult | Female | Aged | Index Medicus
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7. Full Text Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
by Shaw, Leslie M and Vanderstichele, Hugo and Knapik‐Czajka, Malgorzata and Clark, Christopher M and Aisen, Paul S and Petersen, Ronald C and Blennow, Kaj and Soares, Holly and Simon, Adam and Lewczuk, Piotr and Dean, Robert and Siemers, Eric and Potter, William and Lee, Virginia M.‐Y and Trojanowski, John Q and Alzheimer's Dis Neuroimaging Initi and Alzheimer's Disease Neuroimaging Initiative and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Annals of neurology, ISSN 0364-5134, 04/2009, Volume 65, Issue 4, pp. 403 - 413
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Phosphorylation | Apolipoprotein E4 - genetics | Area Under Curve | Humans | Middle Aged | Male | Threonine - metabolism | tau Proteins - chemistry | Alzheimer Disease - pathology | Sensitivity and Specificity | Statistics, Nonparametric | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Female | Retrospective Studies | Cognition Disorders - cerebrospinal fluid | Peptide Fragments - cerebrospinal fluid | Cognition Disorders - pathology | Cognition Disorders - genetics | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Disease Progression | Diagnostic Imaging | ROC Curve | Aged | Biomarkers - cerebrospinal fluid | Alzheimer Disease - genetics | Cohort Studies | Neuroimaging | Neurodegenerative diseases | Threonine | biomarkers | Cognitive ability | Data processing | Cerebrospinal fluid | Regression analysis | Tau protein | Autopsy | Alzheimer's disease | Immunoassays | Geriatrics | Index Medicus | Peptide Fragments | pathology | Biological Markers | MEDICIN OCH HÄLSOVETENSKAP | tau Proteins | 80 and over | genetics | MEDICAL AND HEALTH SCIENCES | chemistry | Apolipoprotein E4 | Alzheimer Disease | Statistics | Amyloid beta-Protein | Nonparametric | Cognition Disorders | cerebrospinal fluid | metabolism
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8. Full Text Cerebrospinal fluid β‐glucocerebrosidase activity is reduced in parkinson's disease patients
by Parnetti, Lucilla and Paciotti, Silvia and Eusebi, Paolo and Dardis, Andrea and Zampieri, Stefania and Chiasserini, Davide and Tasegian, Anna and Tambasco, Nicola and Bembi, Bruno and Calabresi, Paolo and Beccari, Tommaso
Movement disorders, ISSN 0885-3185, 10/2017, Volume 32, Issue 10, pp. 1423 - 1431
Parkinson's disease | β‐glucocerebrosidase | GBA1 gene | CSF biomarkers | lysosomal enzyme activity | β-glucocerebrosidase | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Glucosylceramidase - genetics | Peptide Fragments - cerebrospinal fluid | Humans | Middle Aged | Male | Statistics as Topic | tau Proteins - cerebrospinal fluid | Parkinson Disease - genetics | Glucosylceramidase - cerebrospinal fluid | Mutation - genetics | beta-N-Acetylhexosaminidases - cerebrospinal fluid | Lysosomes - metabolism | alpha-Synuclein - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Amyloid beta-Peptides - cerebrospinal fluid | Female | ROC Curve | Aged | Cathepsin D - cerebrospinal fluid | Enzymes | Neurodegenerative diseases | Lysosomal enzymes | Cognitive ability | Parkinsons disease | Cathepsin D | Glucosylceramidase | Cerebrospinal fluid | Mutation | Movement disorders | Index Medicus
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9. Full Text α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies
by van Steenoven, Inger and Majbour, Nour K and Vaikath, Nishant N and Berendse, Henk W and van der Flier, Wiesje M and van de Berg, Wilma D. J and Teunissen, Charlotte E and Lemstra, Afina W and el-Agnaf, Omar M. A
Movement disorders, ISSN 0885-3185, 11/2018, Volume 33, Issue 11, pp. 1724 - 1733
dementia with Lewy bodies | Neuroscience(all) | biomarkers | α-synuclein | CSF | α‐synuclein | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Parkinson Disease - diagnostic imaging | Peptide Fragments - cerebrospinal fluid | Humans | Middle Aged | Tomography, Emission-Computed, Single-Photon | Male |