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Trends in neurosciences (Regular ed.), ISSN 0166-2236, 2009, Volume 32, Issue 11, pp. 591 - 601
Journal Article
Nature (London), ISSN 1476-4687, 08/2017, Volume 549, Issue 7672, pp. 389 - 393
The pathophysiology of neurodegenerative diseases is poorly understood and there are few therapeutic options... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Microglia - metabolism | Clone Cells - enzymology | Humans | Male | Myeloid Progenitor Cells - enzymology | Extracellular Signal-Regulated MAP Kinases - metabolism | MAP Kinase Signaling System | Erythroid Precursor Cells - enzymology | Histiocytosis - pathology | Microglia - pathology | Female | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Histiocytosis - enzymology | Myeloid Progenitor Cells - metabolism | Neurodegenerative Diseases - pathology | Macrophages - pathology | Microglia - enzymology | Neurodegenerative Diseases - genetics | Myeloid Progenitor Cells - pathology | Histiocytosis - metabolism | Neurodegenerative Diseases - metabolism | Clone Cells - metabolism | Macrophages - enzymology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Erythroid Precursor Cells - pathology | Macrophages - metabolism | Animals | Clone Cells - pathology | Proto-Oncogene Proteins B-raf - genetics | Histiocytosis - genetics | Erythroid Precursor Cells - metabolism | Mosaicism | Mice | Mutation | Neurodegenerative Diseases - enzymology | Physiological aspects | Nervous system | Development and progression | Degeneration | Genetic aspects | Research | Histiocytosis | Mitogen-activated protein kinases | Intervention | Disease | Stem cell transplantation | Activation | Genomes | Kinases | Macrophages | Neuronal-glial interactions | Genotype & phenotype | Allografts | Neurodegeneration | Rodents | Bone marrow | Ataxia | Alzheimer's disease | Myeloid cells | Cytokines | Neurodegenerative diseases | Fetuses | Extracellular signal-regulated kinase | MAP kinase | Cell lineage | Gene expression | Patients | Amyloid precursor protein | Microglia | Organogenesis | Diseases | Neurological diseases | Gliosis | Stem cells | Neural stem cells | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0178622 - e0178622
... of human demyelinating diseases, including multiple sclerosis. In this study, we investigated the role of acid sphingomyelinase in demyelination and myelin repair... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Amyloid Precursor Protein Secretases - genetics | Sphingomyelin Phosphodiesterase - genetics | Axons - enzymology | Recovery of Function - drug effects | Cell Count | Humans | Astrocytes - pathology | Male | Astrocytes - enzymology | Multiple Sclerosis - prevention & control | Multiple Sclerosis - chemically induced | Synaptophysin - genetics | Oligodendroglia - drug effects | Cuprizone | Microglia - pathology | Demyelinating Diseases - chemically induced | Demyelinating Diseases - pathology | Disease Models, Animal | Synaptophysin - metabolism | Astrocytes - drug effects | Multiple Sclerosis - enzymology | Demyelinating Diseases - enzymology | Microglia - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Axons - drug effects | Microglia - enzymology | Demyelinating Diseases - prevention & control | Mice, Knockout | Sphingomyelin Phosphodiesterase - deficiency | Oligodendroglia - pathology | Amyloid Precursor Protein Secretases - metabolism | Animals | Sphingomyelin Phosphodiesterase - antagonists & inhibitors | Axons - pathology | Nerve Regeneration - drug effects | Multiple Sclerosis - pathology | Oligodendroglia - enzymology | Mice | Amitriptyline - pharmacology | Immunohistochemistry | Animal experimentation | Usage | Multiple sclerosis | Analysis | Amyloid beta-protein | Research | Gene expression | Brain | Neurosciences | Laboratories | Sphingolipids | Activation | Recovery | Neuronal-glial interactions | Western blotting | Proteins | Demyelination | Rodents | Ceramide | Fibroblasts | Inhibition | Repair | Damage | Growth factors | Alzheimer's disease | Injuries | Activation analysis | Synaptophysin | Amitriptyline | Demyelinating diseases | Myelin | Patients | Amyloid precursor protein | Sphingomyelin phosphodiesterase | Diseases | Studies | Neurology | Myelination | Acids | Sphingomyelin | Regulation | Molecular biology | Apoptosis | Index Medicus
Journal Article