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Science, ISSN 0036-8075, 3/2011, Volume 331, Issue 6021, pp. 1199 - 1203
Journal Article
Journal Article
Pathology, ISSN 0031-3025, 02/2013, Volume 45, Issue 2, pp. 116 - 126
BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its... 
pathology | familial cancer | uveal melanoma | skin | diagnosis | inherited tumour susceptibility | melanoma | 3p21 loss syndrome | atypical Spitz tumour | germline mutation | BAP1 | Pathology | Inherited tumour susceptibility | Melanoma | Uveal melanoma | Atypical Spitz tumour | Familial cancer | Germline mutation | Skin | Diagnosis | PLEURAL MESOTHELIOMA | DNA-DAMAGE RESPONSE | BRCA1-ASSOCIATED PROTEIN-1 | RENAL-CELL CARCINOMA | BREAST-CANCER | POLYCOMB GROUP PROTEINS | SPITZ NEVI | HISTONE DEACETYLASE INHIBITORS | MALIGNANT MESOTHELIOMA | MYELODYSPLASTIC SYNDROMES | Neoplasms - metabolism | Carcinoma, Neuroendocrine - diagnosis | Melanoma - diagnosis | Humans | Lung Neoplasms - metabolism | Meningioma - genetics | Neoplasms - diagnosis | Paraganglioma - diagnosis | Adenocarcinoma - metabolism | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Gene Deletion | Nevus, Epithelioid and Spindle Cell - genetics | Skin Neoplasms - diagnosis | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Adenocarcinoma - genetics | Uveal Neoplasms - metabolism | Carcinoma, Neuroendocrine - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease | Meningioma - metabolism | Paraganglioma - genetics | Carcinoma, Neuroendocrine - genetics | Mesothelioma - diagnosis | Mesothelioma - genetics | Nevus, Epithelioid and Spindle Cell - metabolism | Ubiquitin Thiolesterase - genetics | Skin Neoplasms - metabolism | Immunohistochemistry - methods | Nevus, Epithelioid and Spindle Cell - diagnosis | Adenocarcinoma - diagnosis | Mesothelioma - metabolism | Paraganglioma - metabolism | Skin Neoplasms - genetics | Uveal Neoplasms - diagnosis | Biomarkers, Tumor - genetics | Meningioma - diagnosis | Mutation | Lung Neoplasms - diagnosis
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2015, Volume 7, Issue 302, pp. 302ra136 - 302ra136
Journal Article
Cancer Discovery, ISSN 2159-8274, 11/2011, Volume 1, Issue 6, pp. 487 - 495
Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer that most commonly evolves from preexisting prostate adenocarcinoma (PCA).... 
REARRANGEMENT | FUSION | ONCOLOGY | ADENOCARCINOMA | KINASE | SMALL-CELL CARCINOMA | N-MYC | COMMON | DIFFERENTIATION | EXPRESSION | Oncogene Proteins - genetics | Prostatic Neoplasms - metabolism | Adenocarcinoma - pathology | Carcinoma, Small Cell - genetics | Gene Expression - drug effects | Gene Expression - genetics | Humans | Male | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Prostate - metabolism | Aurora Kinase A | Adenocarcinoma - metabolism | Prostatic Neoplasms - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Prostate - drug effects | Adenocarcinoma - genetics | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Prostatic Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Neuroendocrine Tumors - pathology | Prostatic Neoplasms - pathology | Carcinoma, Small Cell - metabolism | Neuroendocrine Tumors - metabolism | Carcinoma, Small Cell - drug therapy | Oncogene Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Aurora Kinases | Adenocarcinoma - drug therapy | Disease Progression | Neuroendocrine Tumors - genetics | Protein Kinase Inhibitors - therapeutic use | Cell Line, Tumor | Neuroendocrine Tumors - drug therapy | Cohort Studies | drug targets | aurora kinase A | neuroendocrine prostate cancer | n-myc
Journal Article
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 10/2013, Volume 20, Issue 5, pp. 649 - 657
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 5/2013, Volume 40, Issue 5, pp. 800 - 816
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 1, pp. 23 - 38
Neuroendocrine (NE) phenotype, seen in >30% of prostate adenocarcinomas (PCa), and NE prostate tumors are implicated in aggressive prostate cancer. Formation... 
CELLCYCLE | TRANSCRIPTION FACTORS | HYPOXIA-INDUCIBLE FACTOR | STEM-CELLS | TRANSGENIC ADENOCARCINOMA | ONCOLOGY | MOUSE | CELL-PROLIFERATION | DIFFERENTIATION | MODEL | SIAH UBIQUITIN LIGASE | CANCER | Neurosecretory Systems - pathology | Liver Neoplasms, Experimental - secondary | Prostatic Neoplasms - metabolism | Adenocarcinoma - pathology | Hepatocyte Nuclear Factor 3-beta - genetics | Humans | Lung Neoplasms - metabolism | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Male | Ubiquitin-Protein Ligases - physiology | Prostate - metabolism | Liver Neoplasms, Experimental - metabolism | Prostate - pathology | Adenocarcinoma - metabolism | Prostatic Neoplasms - genetics | Lung Neoplasms - secondary | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Neurosecretory Systems - metabolism | Female | Adenocarcinoma - genetics | Liver Neoplasms, Experimental - genetics | Hepatocyte Nuclear Factor 3-beta - metabolism | Lung Neoplasms - genetics | Neuroendocrine Tumors - pathology | Prostatic Neoplasms - pathology | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Neuroendocrine Tumors - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Lymphatic Metastasis | Mice, Knockout | Neuroendocrine Tumors - genetics | Phenotype | Animals | Cell Line, Tumor | Mice | Tumors
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2014, Volume 111, Issue 23, pp. E2404 - E2413
Journal Article