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Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Development (Cambridge), ISSN 0950-1991, 11/2013, Volume 140, Issue 22, pp. 4510 - 4521
Muller glia function as retinal stem cells in adult zebrafish. In response to loss of retinal neurons, Muller glia partially dedifferentiate, re-express... 
Müller glia | N-cadherin | Retinal regeneration | Alcama | Muller glia | STEM-CELLS | DEDIFFERENTIATION | PROLIFERATION | DEVELOPMENTAL BIOLOGY | GOLDFISH RETINA | ADULT ZEBRAFISH | VERTEBRATE RETINA | ROD PHOTORECEPTORS | SIGNALING PATHWAY | NEUROGENESIS | LINEAGE | Cadherins - metabolism | Multipotent Stem Cells - metabolism | Photoreceptor Cells, Vertebrate - drug effects | Ependymoglial Cells - metabolism | Neural Stem Cells - cytology | Neuroepithelial Cells - cytology | Retinal Ganglion Cells - metabolism | Retinal Neurons - cytology | Retinal Ganglion Cells - cytology | Neurogenesis - drug effects | Retinal Neurons - drug effects | Asymmetric Cell Division - drug effects | Ouabain - pharmacology | Biomarkers - metabolism | Cell Dedifferentiation - drug effects | Zebrafish Proteins - metabolism | Neural Stem Cells - drug effects | Photoreceptor Cells, Vertebrate - cytology | Cell Adhesion - drug effects | Ependymoglial Cells - drug effects | Regeneration - drug effects | Animals | Retinal Neurons - metabolism | Models, Biological | Multipotent Stem Cells - cytology | Zebrafish - metabolism | Ependymoglial Cells - cytology | Heterozygote | Neuroepithelial Cells - metabolism | Photoreceptor Cells, Vertebrate - metabolism | Cell Cycle - drug effects | Neural Stem Cells - metabolism | Retinal Ganglion Cells - drug effects | Index Medicus | Stem Cells and Regeneration
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 12/2016, Volume 420, Issue 1, pp. 120 - 135
Journal Article
STEM CELLS, ISSN 1066-5099, 02/2007, Volume 25, Issue 2, pp. 411 - 418
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2012, Volume 15, Issue 5, pp. 713 - 721
The Huntington's disease gene product, huntingtin, is indispensable for neural tube formation, but its role is obscure. We studied neurulation in htt-null... 
TARGETED DISRUPTION | ZEBRAFISH | LACKING HUNTINGTIN | EMBRYONIC STEM-CELLS | MUTANT HUNTINGTIN | ADAM10 | MICE | DISEASE GENE HOMOLOG | WILD-TYPE HUNTINGTIN | NEUROSCIENCES | N-CADHERIN CLEAVAGE | Body Patterning - drug effects | Guanylate Kinases - genetics | Amyloid Precursor Protein Secretases - genetics | RNA, Small Interfering - genetics | Wnt1 Protein - genetics | Brain - embryology | PAX2 Transcription Factor - metabolism | Cadherins - metabolism | Apoptosis - drug effects | Embryo, Mammalian | Hedgehog Proteins - metabolism | Apoptosis - genetics | Green Fluorescent Proteins - genetics | Brain - metabolism | NFI Transcription Factors - metabolism | Cadherins - genetics | Tissue Inhibitor of Metalloproteinase-1 - pharmacology | Discs Large Homolog 1 Protein | Membrane Proteins - genetics | Gene Expression Regulation, Developmental - drug effects | PAX2 Transcription Factor - genetics | Cell Adhesion - drug effects | Mutation - genetics | Biological Evolution | Brain - drug effects | Huntingtin Protein | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Analysis of Variance | Membrane Proteins - antagonists & inhibitors | Cell Adhesion - physiology | Embryo, Nonmammalian | Guanylate Kinases - metabolism | Neuroepithelial Cells - physiology | Mice | Zebrafish Proteins - genetics | ADAM Proteins - genetics | Cerebral Ventricles - cytology | Drosophila melanogaster | Neuroepithelial Cells - drug effects | Embryonic Stem Cells - metabolism | Nestin | Immunoprecipitation | Gene Expression Regulation, Developmental - genetics | Wnt1 Protein - metabolism | Zebrafish - embryology | Cell Differentiation - genetics | Transfection | Hedgehog Proteins - genetics | Intermediate Filament Proteins - genetics | Neurons - physiology | Membrane Proteins - metabolism | Cerebral Ventricles - embryology | Neurons - drug effects | Nuclear Proteins - genetics | Hydroxamic Acids - pharmacology | Green Fluorescent Proteins - metabolism | Brain - cytology | ADAM Proteins - antagonists & inhibitors | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Dipeptides - pharmacology | Cells, Cultured | ADAM10 Protein | Morpholines - pharmacology | Nuclear Proteins - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Dictyostelium | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Body Patterning - genetics | Huntington's chorea | Physiological aspects | Cadherins | Genetic aspects | Research | Embryonic stem cells | Risk factors
Journal Article
Journal of Experimental Biology, ISSN 0022-0949, 11/2012, Volume 215, Issue 22, pp. 3881 - 3894
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56117
Background: Neural progenitor cells (NPCs) in the developing neuroepithelium are regulated by intrinsic and extrinsic factors. There is evidence that NPCs form... 
STEM-CELLS | ADULT NEUROGENESIS | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR GENE | KUNITZ DOMAINS | SERINE-PROTEASE INHIBITOR | NEURONAL DIFFERENTIATION | TYPE-1 HAI-1 | RAT HIPPOCAMPUS | TUBE CLOSURE | GLIOBLASTOMA CELLS | Bone Morphogenetic Protein 2 - pharmacology | Membrane Glycoproteins - metabolism | Rats, Wistar | Humans | Neural Stem Cells - drug effects | Bone Morphogenetic Protein Receptors - metabolism | Rats | Neural Stem Cells - cytology | Neuroepithelial Cells - cytology | Bone Morphogenetic Protein 4 - pharmacology | Membrane Glycoproteins - genetics | Neuroglia - drug effects | Gene Expression Regulation - drug effects | Neuroglia - cytology | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Neuroepithelial Cells - metabolism | Phosphorylation - drug effects | Neural Stem Cells - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Neuroepithelial Cells - drug effects | Protease inhibitors | Proteases | Stem cells | Bone morphogenetic proteins | Transplantation | Cell differentiation | Embryonic stem cells | Intermediate filament proteins | Cell proliferation | Neonates | Brain | Cell culture | Serine | Differentiation (biology) | Embryo cells | Radial glial cells | Stem cell transplantation | Biochemistry | Kinases | Neurogenesis | Cell surface | Cell adhesion & migration | Proteins | Cell growth | Allografts | Cell fate | Protease | Rodents | Neostriatum | Growth factors | Medical research | Immunoglobulins | Bone morphogenetic protein 4 | Bone morphogenetic protein 2 | Developmental biology | Hepatocyte growth factor | RNA-mediated interference | Molecular interactions | Glial fibrillary acidic protein | Cell division | Proteinase inhibitors | siRNA | Gene expression | Ribonucleic acid--RNA | Signaling | Brain research | Plasmids | Cells (biology) | Neural stem cells | Serine proteinase | Bone | RNA | Ribonucleic acid
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 45, Issue 6, pp. 873 - 886
It has been debated whether asymmetric distribution of cell surface receptors during mitosis could generate asymmetric cell divisions by yielding daughters... 
NEURAL STEM-CELLS |