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1. Full Text Whole-genome characterization of chemoresistant ovarian cancer
by Patch, Ann-Marie and Christie, Elizabeth L and Etemadmoghadam, Dariush and Garsed, Dale W and George, Joshy and Fereday, Sian and Nones, Katia and Cowin, Prue and Alsop, Kathryn and Bailey, Peter J and Kassahn, Karin S and Newell, Felicity and Quinn, Michael C.J and Kazakoff, Stephen and Quek, Kelly and Wilhelm-Benartzi, Charlotte and Curry, Ed and Leong, Huei San and Hamilton, Anne and Mileshkin, Linda and Au-Yeung, George and Kennedy, Catherine and Hung, Jillian and Chiew, Yoke-Eng and Harnett, Paul and Friedlander, Michael and Quinn, Michael and Pyman, Jan and Cordner, Stephen and O'Brien, Patricia and Leditschke, Jodie and Young, Greg and Strachan, Kate and Waring, Paul and Azar, Walid and Mitchell, Chris and Traficante, Nadia and Hendley, Joy and Thorne, Heather and Shackleton, Mark and Miller, David K and Arnau, Gisela Mir and Tothill, Richard W and Holloway, Timothy P and Semple, Timothy and Harliwong, Ivon and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Idrisoglu, Senel and Bruxner, Timothy J. C and Christ, Angelika N and Poudel, Barsha and Holmes, Oliver and Anderson, Matthew and Leonard, Conrad and Lonie, Andrew and Hall, Nathan and Wood, Scott and Taylor, Darrin F and Xu, Qinying and Lynn Fink, J and Waddell, Nick and Drapkin, Ronny and Stronach, Euan and Gabra, Hani and Brown, Robert and Jewell, Andrea and Nagaraj, Shivashankar H and Markham, Emma and Wilson, Peter J and Ellul, Jason and McNally, Orla and Doyle, Maria A and Vedururu, Ravikiran and Stewart, Collin and Lengyel, Ernst and Pearson, John V and Waddell, Nicola and Defazio, Anna and Grimmond, Sean M and Bowtell, David D. L and Australian Ovarian Canc Study Grp and Australian Ovarian Cancer Study Group and The Australian Ovarian Cancer Study Group
Nature (London), ISSN 0028-0836, 05/2015, Volume 521, Issue 7553, pp. 489 - 494
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oncogene Proteins - genetics | PTEN Phosphohydrolase - genetics | Humans | Mutagenesis - genetics | Cystadenocarcinoma, Serous - genetics | DNA-Binding Proteins - genetics | Genes, Neurofibromatosis 1 | Germ-Line Mutation - genetics | Cyclin E - genetics | Cystadenocarcinoma, Serous - drug therapy | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Ovarian Neoplasms - genetics | DNA Methylation | Drug Resistance, Neoplasm - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | DNA Mutational Analysis | Retinoblastoma Protein - genetics | Genes, BRCA2 | Female | Genes, BRCA1 | Ovarian Neoplasms - drug therapy | Cohort Studies | Drug Resistance, Neoplasm - drug effects | Care and treatment | Analysis | Genetic aspects | Nucleotide sequencing | Methylation | Ovarian cancer | DNA sequencing | Gene amplification | Genomes | Mutation | Metastasis | Gene expression | Chromosomes | Patients | Tumors | Index Medicus
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2. Full Text Whole-genome landscapes of major melanoma subtypes
by Hayward, Nicholas K and Hayward, Nicholas K and Wilmott, James S and Wilmott, James S and Waddell, Nicola and Waddell, Nicola and Johansson, Peter A and Johansson, Peter A and Field, Matthew A and Field, Matthew A and Nones, Katia and Nones, Katia and Patch, Ann-Marie and Patch, Ann-Marie and Kakavand, Hojabr and Kakavand, Hojabr and Alexandrov, Ludmil B and Alexandrov, Ludmil B and Burke, Hazel and Burke, Hazel and Jakrot, Valerie and Jakrot, Valerie and Kazakoff, Stephen and Kazakoff, Stephen and Holmes, Oliver and Holmes, Oliver and Leonard, Conrad and Leonard, Conrad and Sabarinathan, Radhakrishnan and Sabarinathan, Radhakrishnan and Mularoni, Loris and Mularoni, Loris and Wood, Scott and Wood, Scott and Xu, Qinying and Xu, Qinying and Waddell, Nick and Waddell, Nick and Tembe, Varsha and Tembe, Varsha and Pupo, Gulietta M and Pupo, Gulietta M and De Paoli-Iseppi, Ricardo and De Paoli-Iseppi, Ricardo and Vilain, Ricardo E and Vilain, Ricardo E and Shang, Ping and Shang, Ping and Lau, Loretta M S and Lau, Loretta M. S and Dagg, Rebecca A and Dagg, Rebecca A and Schramm, Sarah-Jane and Schramm, Sarah-Jane and Pritchard, Antonia and Pritchard, Antonia and Dutton-Regester, Ken and Dutton-Regester, Ken and Newell, Felicity and Newell, Felicity and Fitzgerald, Anna and Fitzgerald, Anna and Shang, Catherine A and Shang, Catherine A and Grimmond, Sean M and Grimmond, Sean M and Pickett, Hilda A and Pickett, Hilda A and Yang, Jean Y and Yang, Jean Y and Stretch, Jonathan R and Stretch, Jonathan R and Behren, Andreas and Behren, Andreas and Kefford, Richard F and Kefford, Richard F and Hersey, Peter and Hersey, Peter and Long, Georgina V and Long, Georgina V and Cebon, Jonathan and Cebon, Jonathan and Shackleton, Mark and Shackleton, Mark and Spillane, Andrew J and Spillane, Andrew J and Saw, Robyn P. M and Saw, Robyn P M and López-Bigas, Núria and López-Bigas, Núria and Pearson, John V and Pearson, John V and Thompson, John F and Thompson, John F and Scolyer, Richard A and Scolyer, Richard A and Mann, Graham J and Mann, Graham J and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature (London), ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 175 - 180
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Membrane Proteins - genetics | Humans | X-linked Nuclear Protein | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Mutation - genetics | Genes, p16 | Genome, Human - genetics | Tumor Suppressor Protein p53 - genetics | Ultraviolet Rays - adverse effects | Telomerase - genetics | Signal Transduction - drug effects | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Mitogen-Activated Protein Kinases - genetics | Neurofibromatosis 1 - genetics | Melanoma - classification | Nuclear Proteins - genetics | DNA Helicases - genetics | Telomere - genetics | Genetic research | Genetic aspects | Genomes | Research | Melanoma | Medical research | Pathogenesis | U.V. radiation | Mucosa | p53 Protein | Genes | MAP kinase | Auroral kilometric radiation | Kinases | Gene sequencing | Telomeres | Ultraviolet radiation | Carcinogens | Mutagenesis | Protein kinase | Mutation | Signatures | Index Medicus | Biological Science | 60 APPLIED LIFE SCIENCES
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3. Full Text Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
by Ophir Shalem and Neville E. Sanjana and Ella Hartenian and Xi Shi and David A. Scott and Tarjei S. Mikkelsen and Dirk Heckl and Benjamin L. Ebert and David E. Root and John G. Doench and Feng Zhang
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2014, Volume 343, Issue 6166, pp. 84 - 87
T lymphocytes | HEK293 cells | Genetic vectors | Genomics | REPORTS | Cell lines | Stem cells | Melanoma | Genetic loci | Genetic mutation | Genetic screening | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genome-Wide Association Study | Gene Library | raf Kinases - antagonists & inhibitors | Humans | Selection, Genetic | Cell Survival - genetics | Mediator Complex - genetics | Genetic Loci | Transcription Factors - genetics | Gene Knockout Techniques | Genes, Neurofibromatosis 1 | Genes, Neurofibromatosis 2 | Genetic Testing - methods | Lentivirus | Cullin Proteins - genetics | Pluripotent Stem Cells - metabolism | Drug Resistance, Neoplasm - genetics | Sulfonamides - therapeutic use | Melanoma - genetics | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Adaptor Proteins, Signal Transducing - genetics | Clustered Regularly Interspaced Short Palindromic Repeats | Indoles - therapeutic use | RNA sequencing | Genome-wide association studies | Research | Studies | Genetic engineering | Pharmaceutical sciences | Index Medicus
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4. Full Text The molecular landscape of glioma in patients with Neurofibromatosis 1
by D’Angelo, Fulvio and Ceccarelli, Michele and Tala, Tala and Garofano, Luciano and Zhang, Jing and Frattini, Véronique and Caruso, Francesca P and Lewis, Genevieve and Alfaro, Kristin D and Bauchet, Luc and Berzero, Giulia and Cachia, David and Cangiano, Mario and Capelle, Laurent and de Groot, John and DiMeco, Francesco and Ducray, François and Farah, Walid and Finocchiaro, Gaetano and Goutagny, Stéphane and Kamiya-Matsuoka, Carlos and Lavarino, Cinzia and Loiseau, Hugues and Lorgis, Véronique and Marras, Carlo E and McCutcheon, Ian and Nam, Do-Hyun and Ronchi, Susanna and Saletti, Veronica and Seizeur, Romuald and Slopis, John and Suñol, Mariona and Vandenbos, Fanny and Varlet, Pascale and Vidaud, Dominique and Watts, Colin and Tabar, Viviane and Reuss, David E and Kim, Seung-Ki and Meyronet, David and Mokhtari, Karima and Salvador, Hector and Bhat, Krishna P and Eoli, Marica and Sanson, Marc and Lasorella, Anna and Iavarone, Antonio
Nature medicine, ISSN 1078-8956, 01/2019, Volume 25, Issue 1, pp. 176 - 187
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Humans | Middle Aged | Child, Preschool | Male | Brain Neoplasms - complications | Germ-Line Mutation - genetics | X-linked Nuclear Protein - genetics | Glioma - complications | Glioma - genetics | Young Adult | Brain Neoplasms - immunology | Antigens, Neoplasm - metabolism | Adult | Female | Neurofibromatosis 1 - genetics | Child | Reproducibility of Results | Brain Neoplasms - genetics | Glioma - immunology | DNA Methylation - genetics | Transcriptome - genetics | Adolescent | Neurofibromatosis 1 - complications | T-Lymphocytes - immunology | Neurofibromin 1 - genetics | Cohort Studies | Care and treatment | Gene mutations | Gliomas | Neurofibromatosis | Physiological aspects | Development and progression | Genetic aspects | Gene expression | Health aspects | Chromatin | Transcription | Brain tumors | p53 Protein | Gene regulation | MAP kinase | Neurofibromin 1 | Lymphocytes T | Homozygosity | Patients | Recklinghausen's disease | Neoplasms | Subgroups | 1-Phosphatidylinositol 3-kinase | Alterations | Life span | Glioma | DNA methylation | Mutation | Isocitrate dehydrogenase | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Life Sciences
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5. Full Text Comprehensive genomic characterization defines human glioblastoma genes and core pathways
by Chin, L and Meyerson, M and Aldape, K and Bigner, D and Mikkelsen, T and VandenBerg, S and Kahn, A and Penny, R and Gerhard, D. S and Getz, G and Brennan, C and Taylor, B. S and Winckler, W and Park, P and Ladanyi, M and Hoadley, K. A and Verhaak, R. G. W and Hayes, D. N and Spellman, Paul T and Absher, D and Weir, B. A and Ding, L and Wheeler, D and Lawrence, M. S and Cibulskis, K and Mardis, E and Zhang, Jinghui and Wilson, R. K and Donehower, L and Wheeler, D. A and Purdom, E and Wallis, J and Laird, P. W and Herman, J. G and Schuebel, K. E and Weisenberger, D. J and Baylin, S. B and Schultz, N and Yao, Jun and Wiedemeyer, R and Weinstein, J and Sander, C and Gibbs, R. A and Gray, J and Kucherlapati, R and Lander, E. S and Myers, R. M and Perou, C. M and McLendon, Roger and Friedman, Allan and Tissue Source Sites and Canc Genome Atlas Res Network and Canc Genome Characterization Ctr and Genome Sequencing Ctr and Project Teams and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature (London), ISSN 0028-0836, 10/2008, Volume 455, Issue 7216, pp. 1061 - 1068
PIK3CA GENE | ALKYLATING-AGENTS | HIGH-FREQUENCY | MALIGNANT GLIOMAS | MISMATCH REPAIR | CELL-LINES | NF1 GENE | TUMORS | NEUROFIBROMATOSIS TYPE-1 | SOMATIC MUTATIONS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Tumors of the nervous system. Phacomatoses | Genomics | Humans | Middle Aged | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Male | DNA Repair - genetics | DNA Methylation | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Adult | Female | Retrospective Studies | Genes, Tumor Suppressor | Protein Structure, Tertiary | Genes, erbB-1 - genetics | Brain Neoplasms - genetics | Models, Molecular | Gene Dosage | Signal Transduction - genetics | Mutation - genetics | Genome, Human - genetics | Phosphatidylinositol 3-Kinases - genetics | DNA Modification Methylases - genetics | Adolescent | Aged | Neurofibromin 1 - genetics | Genetic aspects | Research | Gene expression | Glioblastoma multiforme | Cancer cells | Genotype & phenotype | Public access | Genetics | Patients | Deoxyribonucleic acid--DNA | Methods | Cancer | Index Medicus
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