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Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 247 - 251
The polycomb repressive complex 2 (PRC2) exerts oncogenic effects in many tumour types(1). However, loss-of-function mutations in PRC2 components occur in a... 
SUPPRESSOR | GENE | MULTIDISCIPLINARY SCIENCES | MICE | NF1 MICRODELETION PATIENTS | MUTATIONS | BET BROMODOMAIN INHIBITION | CANCER | TUMORS | NEUROFIBROMATOSIS TYPE-1 | EZH2 | Chromatin - metabolism | Transcription, Genetic - drug effects | Polycomb Repressive Complex 2 - genetics | Humans | Transcription Factors - deficiency | ras Proteins - metabolism | Neurofibromin 1 - deficiency | Glioma - genetics | Neoplasms - genetics | Melanoma - genetics | Tumor Suppressor Proteins - deficiency | Glioma - pathology | Nerve Sheath Neoplasms - pathology | Nuclear Proteins - deficiency | Tumor Suppressor Proteins - genetics | Epigenesis, Genetic - drug effects | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Nuclear Proteins - genetics | Chromatin - drug effects | Nerve Sheath Neoplasms - drug therapy | Disease Models, Animal | Triazoles - therapeutic use | Nerve Sheath Neoplasms - genetics | Tumor Suppressor Proteins - metabolism | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | ras Proteins - antagonists & inhibitors | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Melanoma - pathology | Transcription Factors - genetics | Azepines - therapeutic use | Neoplasms - drug therapy | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Animals | Polycomb Repressive Complex 2 - deficiency | Melanoma - drug therapy | Nuclear Proteins - antagonists & inhibitors | Mice | Neoplasms - pathology | Polycomb Repressive Complex 2 - metabolism | Chromatin - genetics | Neurofibromin 1 - genetics | Glioma - drug therapy | Epigenetic inheritance | Ras genes | Genetic transcription | Research | Gliomas | Studies | Mutation | Genes | Tumors | Defects
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2014, Volume 46, Issue 11, pp. 1227 - 1232
Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9679, pp. 1974 - 1986
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 5, pp. 682 - 694
Journal Article
Oncogene, ISSN 0950-9232, 04/2013, Volume 32, Issue 14, pp. 1821 - 1830
The Salvador/Warts/Hippo (Hippo) signaling pathway defines a novel signaling cascade regulating cell contact inhibition, organ size control, cell growth,... 
KIBRA | Willin | breast cancer | Hippo pathway | Merlin | claudin-low | APOPTOSIS | PROTEIN | ORGAN SIZE CONTROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | YAP | PROLIFERATION | DROSOPHILA | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER CELLS | ONCOGENE | ONCOLOGY | CYCLE EXIT | GENETICS & HEREDITY | RNA, Small Interfering - genetics | Neurofibromin 2 - genetics | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Cytoskeletal Proteins - genetics | Humans | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Immunoenzyme Techniques | Hepatocyte Growth Factor - antagonists & inhibitors | Biomarkers, Tumor - metabolism | Hepatocyte Growth Factor - genetics | Carcinoma, Ductal, Breast - pathology | Carcinoma, Ductal, Breast - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Real-Time Polymerase Chain Reaction | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | Breast - cytology | Membrane Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Blotting, Western | Hepatocyte Growth Factor - metabolism | Breast Neoplasms - genetics | Claudin-1 - genetics | Biomarkers, Tumor - genetics | Cell Movement | Carcinoma, Ductal, Breast - genetics | Phosphorylation | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | Breast - metabolism | Breast Neoplasms - metabolism | Claudin-1 - metabolism | Epithelial-Mesenchymal Transition | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cytoskeletal Proteins - metabolism | Female | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Neurofibromin 2 - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - antagonists & inhibitors | Phosphoproteins - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Breast Neoplasms - pathology | Nuclear Proteins - antagonists & inhibitors | Apoptosis | Cellular proteins | Prognosis | Physiological aspects | Breast cancer | Genetic aspects | Cellular signal transduction | Research | Health aspects | Mammals | Gene expression
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2010, Volume 18, Issue 2, pp. 288 - 299
Journal Article
Genes, Chromosomes and Cancer, ISSN 1045-2257, 08/2012, Volume 51, Issue 8, pp. 743 - 755
Journal Article