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Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications
Journal of medicinal chemistry, ISSN 0022-2623, 09/2015, Volume 58, Issue 18, pp. 7093 - 7118
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Neoplasms - metabolism | Respiratory Tract Diseases - metabolism | Cardiovascular Diseases - drug therapy | Humans | Voltage-Gated Sodium Channels - physiology | Epilepsy - metabolism | Biological Products - pharmacology | Respiratory Tract Diseases - drug therapy | Pain - metabolism | Neuromuscular Diseases - drug therapy | Pain - drug therapy | Voltage-Gated Sodium Channel Blockers - therapeutic use | Protein Subunits - physiology | Voltage-Gated Sodium Channel Blockers - chemistry | Biological Products - therapeutic use | Protein Subunits - genetics | Protein Structure, Tertiary | Voltage-Gated Sodium Channels - genetics | Cardiovascular Diseases - metabolism | Drug Industry | Clinical Trials as Topic | Neuromuscular Diseases - metabolism | Neoplasms - drug therapy | Biological Products - chemistry | Channelopathies - genetics | Animals | Channelopathies - drug therapy | Voltage-Gated Sodium Channel Blockers - pharmacology | Epilepsy - drug therapy | Ligands | Voltage-Gated Sodium Channels - chemistry | Protein Subunits - chemistry | Mutation | Ion Channel Gating | Index Medicus
Journal Article
European journal of neurology, ISSN 1351-5101, 07/2010, Volume 17, Issue 7, pp. 893 - 902
myasthenia gravis | neuromuscular transmission disorders | Lambert–Eaton myasthenic syndrome | neuromyotonia | Lambert-Eaton myasthenic syndrome | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | MEDLINE | Evidence-Based Medicine - methods | Meta-Analysis as Topic | Humans | Isaacs Syndrome - therapy | Myasthenia Gravis - therapy | Autoimmune Diseases - immunology | Clinical Protocols - standards | Isaacs Syndrome - drug therapy | Evidence-Based Medicine - trends | Isaacs Syndrome - immunology | Lambert-Eaton Myasthenic Syndrome - immunology | Lambert-Eaton Myasthenic Syndrome - therapy | Neuromuscular Junction Diseases - drug therapy | Review Literature as Topic | Autoimmune Diseases - therapy | Neuromuscular Junction Diseases - therapy | Myasthenia Gravis - immunology | Neuromuscular Junction Diseases - immunology | Myasthenia Gravis - drug therapy | Autoimmune Diseases - drug therapy | Lambert-Eaton Myasthenic Syndrome - drug therapy | Viral antibodies | Medical colleges | Online health care information services | Myasthenia gravis | Corticosteroids | Immunotherapy | Practice guidelines (Medicine) | Antibodies | Drug therapy | Azathioprine | Index Medicus
Journal Article
Neurotherapeutics, ISSN 1933-7213, 04/2017, Volume 14, Issue 2, pp. 417 - 428
Charcot–Marie–Tooth disease | Acetylated α-tubulin | Compound screening | HSPB1 | Mitochondria | Histone deacetylase 6 | Pharmacology & Pharmacy | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Histone Deacetylase 6 - antagonists & inhibitors | Neuromuscular Junction - drug effects | Charcot-Marie-Tooth Disease - enzymology | Muscle, Skeletal - innervation | Axonal Transport - drug effects | Charcot-Marie-Tooth Disease - drug therapy | Pyrimidines - pharmacology | Animals | Pyrimidines - therapeutic use | Muscle, Skeletal - drug effects | Histone Deacetylase Inhibitors - pharmacology | Hydroxamic Acids - therapeutic use | Histone Deacetylase Inhibitors - therapeutic use | Mice | Tumor Cells, Cultured | Drug Evaluation, Preclinical | Ganglia, Spinal - drug effects | Neurons - drug effects | Hydroxamic Acids - pharmacology | Medicine, Experimental | Medical research | Tubulins | Analysis | Neurophysiology | Index Medicus | Original
Journal Article
Trends in pharmacological sciences (Regular ed.), ISSN 0165-6147, 01/2019, Volume 40, Issue 1, pp. 50 - 70
cyclophilin D | calcium | drug discovery | mPTP | mitochondria | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Mitochondrial Membrane Transport Proteins - metabolism | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Humans | Reperfusion Injury - drug therapy | Drug Discovery - methods | Mitochondria - metabolism | Molecular Targeted Therapy | Neurodegenerative Diseases - drug therapy | Neuromuscular Diseases - drug therapy | Neuromuscular Diseases - physiopathology | Animals | Neurodegenerative Diseases - physiopathology | Cell Death - physiology | Reperfusion Injury - physiopathology | Child | Index Medicus
Journal Article
Neurotherapeutics, ISSN 1933-7213, 7/2016, Volume 13, Issue 3, pp. 555 - 561
Neurology | Neurosciences | Biomedicine | Neurobiology | Cytokine | drug development | Neurosurgery | anticytokine | neurology | Pharmacology & Pharmacy | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cytokines - therapeutic use | Alzheimer Disease - complications | Humans | Nervous System Diseases - drug therapy | Alzheimer Disease - drug therapy | Demyelinating Diseases - complications | Stroke - complications | Treatment Outcome | Clinical Trials as Topic | Stroke - drug therapy | Nervous System Diseases - complications | Neuromuscular Diseases - drug therapy | Multiple Sclerosis - complications | Animals | Encephalitis - drug therapy | Neuromuscular Diseases - complications | Encephalitis - complications | Cytokines - antagonists & inhibitors | Demyelinating Diseases - drug therapy | Multiple Sclerosis - drug therapy | Index Medicus | Review
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 01/2021, Volume 371, Issue 6524, pp. 29 - 31
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gene Transfer Techniques | Exons | Humans | Morpholinos - therapeutic use | Oligonucleotides, Antisense - therapeutic use | Dynamin II - genetics | RNA Precursors - genetics | Dependovirus | Molecular Targeted Therapy | Muscular Dystrophy, Duchenne - therapy | RNA Stability | Genetic Therapy - methods | Drugs | Motor neurons | Neuromuscular diseases | Mental disorders | Peripheral nerves | Muscles | Viruses | Ribonucleic acid--RNA | Drug development | Skeletal muscle | Musculoskeletal system | Nerves | Neuromuscular junctions | Gene therapy | Index Medicus | Life Sciences
Journal Article
Molecular therapy. Methods & clinical development, ISSN 2329-0501, 03/2018, Volume 8, Issue C, pp. 87 - 104
genotoxicity | inherited diseases | AAV | liver immunogenicity | AAV genome | gene therapy | persistence | AAV capsid | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Antigens | Neuromuscular diseases | Disease | Neurodegenerative diseases | Clinical trials | Viruses | Infections | Genomes | Drug development | Vectors (Biology) | Proteins | Plasmids | Blindness | Conflicts of interest | Biomarkers | Gene therapy | Drug dosages | Deoxyribonucleic acid--DNA | Methods | Expression vectors | Life Sciences | Human health and pathology
Journal Article