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Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 534, Issue 7606, pp. 267 - 271
Journal Article
Cell host & microbe, ISSN 1931-3128, 2016, Volume 19, Issue 6, pp. 788 - 799
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2016, Volume 92, Issue 5, pp. 949 - 958
Zika virus (ZIVK) represents a new threat to global health, with particular relevance to neuroscientists, due to associated newborn and adult neurological... 
microcephaly | acute flaccid paralysis | vertical transmission | neurovirology | antibody-mediated enhancement | interferon | Guillain-Barré syndrome | Zika | flavivirus | NEURAL PROGENITORS | FLACCID PARALYSIS | STEM-CELLS | WEST-NILE-VIRUS | CONGENITAL CYTOMEGALOVIRUS-INFECTION | CROSS-REACTIVITY | CENTRAL-NERVOUS-SYSTEM | VERTICAL TRANSMISSION | DENGUE VIRUS | NEUROSCIENCES | BRAIN | Meningoencephalitis - physiopathology | Pregnancy Complications, Infectious - virology | Blindness - physiopathology | Humans | Brain - virology | Interferons - immunology | Microcephaly - virology | Pregnancy Complications, Infectious - physiopathology | Meningoencephalitis - immunology | Pregnancy Complications, Infectious - immunology | Zika Virus Infection - virology | Microcephaly - immunology | Female | Microcephaly - physiopathology | Infant, Newborn | Zika Virus - pathogenicity | Cognitive Dysfunction - virology | Cell Survival | Zika Virus Infection - physiopathology | Brain - physiopathology | Neural Stem Cells - virology | Zika Virus - physiology | Retinal Neurons - virology | Guillain-Barre Syndrome - physiopathology | Cognitive Dysfunction - physiopathology | Pregnancy | Guillain-Barre Syndrome - immunology | Meningoencephalitis - virology | Neurogenesis - physiology | Zika Virus Infection - immunology | Guillain-Barre Syndrome - virology | Blindness - virology | Brain - immunology | Nervous system diseases | Guillain-Barre syndrome | Neurons | Cell death | Analysis | Stem cells | Disease susceptibility | Health aspects | Neurophysiology | Interferon | Paralysis | Biological response modifiers | Brain | Encephalitis | Neurosciences | Congenital diseases | Pandemics | Disease | Neurobiology | Zika virus | Infections | Vaccines | Kinases | Microcephaly | Proteins | Mosquitoes | Rodents | Meningitis
Journal Article
PLoS pathogens, ISSN 1553-7374, 2018, Volume 14, Issue 1, p. e1006764
Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the vertebrate host are poorly understood. In this study, we show for the... 
ENCEPHALITIS-VIRUS | MICROBIOLOGY | ENVELOPE PROTEIN | ENDOCYTOSIS | PATHOGENESIS | VIROLOGY | EXTRACELLULAR VESICLES | TRANSFERRIN RECEPTOR | BIOGENESIS | INFECTED-CELLS | C VIRUS | COMMUNICATION | PARASITOLOGY | Endothelium, Vascular - cytology | Neurons - pathology | Keratinocytes - virology | Coculture Techniques | Humans | Cerebral Cortex - pathology | Cercopithecus aethiops | Encephalitis, Tick-Borne - pathology | Neurons - cytology | Arthropod Vectors - ultrastructure | Cerebral Cortex - cytology | Viral Proteins - metabolism | Encephalitis Viruses, Tick-Borne - ultrastructure | Ixodes - cytology | Cerebral Cortex - ultrastructure | Endothelium, Vascular - ultrastructure | Encephalitis Viruses, Tick-Borne - pathogenicity | Neurons - ultrastructure | Arthropod Vectors - cytology | Encephalitis, Tick-Borne - virology | RNA, Viral - metabolism | Host-Parasite Interactions | Keratinocytes - ultrastructure | Exosomes - ultrastructure | Exosomes - virology | Cell Line | Neurons - virology | Mice, Inbred C57BL | Cells, Cultured | Cerebral Cortex - virology | Keratinocytes - cytology | Encephalitis, Tick-Borne - transmission | Cryoelectron Microscopy | Host-Pathogen Interactions | Ixodes - ultrastructure | Keratinocytes - pathology | Animals | Encephalitis Viruses, Tick-Borne - physiology | Ixodes - virology | Embryo, Mammalian - cytology | Models, Biological | Endothelium, Vascular - virology | Endothelium, Vascular - pathology | Mice | Arthropod Vectors - virology | Encephalitis | Disease transmission | Viral proteins | West Nile fever | Research | Health aspects | Tick-borne diseases | Neuropathogenesis | Clathrin | Tick-borne encephalitis | Pathogenesis | Funding | Ticks | Viruses | Infections | Biochemistry | Vaccines | Exosomes | Aquatic insects | Mammalian cells | Proteins | Blood-brain barrier | Arthropods | Arachnids | RNA viruses | Invasiveness | Keratinocytes | Electron microscopy | Mammals | Ribonucleic acid--RNA | Endothelial cells | Virology | Medicine | Infectious diseases | Microscopy | West Nile virus | Skin | Software | Microvasculature | Molecular biology | Cell migration | Viral infections | RNA | Ribonucleic acid
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 491, Issue 7426, pp. 769 - 773
In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn errors of toll-like receptor 3 (TLR3) immunity are prone to HSV-1... 
TOLL-LIKE RECEPTOR-3 | TLR3 DEFICIENCY | DOUBLE-STRANDED-RNA | HUMAN ES | PROTECTIVE IMMUNITY | VIRUS ENCEPHALITIS | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | CENTRAL-NERVOUS-SYSTEM | HERPES-SIMPLEX ENCEPHALITIS | RETICULAR THALAMIC NEURONS | Neurons - pathology | Encephalitis, Herpes Simplex - immunology | Humans | Central Nervous System - pathology | Interferons - immunology | Central Nervous System - immunology | Membrane Transport Proteins - deficiency | Neural Stem Cells - immunology | Oligodendroglia - immunology | Astrocytes - immunology | Membrane Transport Proteins - genetics | Toll-Like Receptor 3 - deficiency | Herpesvirus 1, Human - immunology | Cell Differentiation | Toll-Like Receptor 3 - genetics | Induced Pluripotent Stem Cells - cytology | Child | Astrocytes - virology | Central Nervous System - virology | Neurons - virology | Disease Susceptibility | Cell Separation | Induced Pluripotent Stem Cells - virology | Neural Stem Cells - virology | Cells, Cultured | Neurons - immunology | Oligodendroglia - virology | Immunity, Innate | Encephalitis, Herpes Simplex - pathology | Oligodendroglia - pathology | Cell Lineage | Central Nervous System - cytology | Encephalitis, Herpes Simplex - virology | Encephalitis, Herpes Simplex - metabolism | Biomarkers | Herpesvirus 1, Human - pathogenicity | Neurons | Stem cells | Physiological aspects | Toll-like receptors | Virulence (Microbiology) | Research | Health aspects | Herpes simplex virus | Proteins | Epidermal growth factor | Patients
Journal Article
Journal Article
Journal Article