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European Journal of Organic Chemistry, ISSN 1434-193X, 05/2017, Volume 2017, Issue 17, pp. 2486 - 2490
Phytoprostanes (PhytoPs) are produced in plants and seeds by non‐enzymatic free‐radical pathways from α‐linolenic acid (ALA). We recently highlighted the... 
Biomarkers | Oxidative stress | Phytofurans | Fatty acids | Total synthesis | CHEMISTRY, ORGANIC | CYCLIC OXYGENATED METABOLITES | PEROXIDATION | DISCOVERY | ISOFURANS | PHYTOPROSTANES F-1 | PRODUCTS | NEUROPROSTANES | DOCOSAHEXAENOIC ACID | NEUROFURANS | STRESS | Analytical chemistry | Organic chemistry | Chemical Sciences
Journal Article
Chemical Communications, ISSN 1359-7345, 09/2015, Volume 51, Issue 86, pp. 15696 - 15699
Journal Article
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 44, pp. 9408 - 9414
A unified strategy for the total synthesis of the methyl esters of all phytoprostane (PhytoP) classes bearing two ring-oxygen atoms based on an orthogonally... 
BIOMARKERS | PHYTOPROSTANES | PROSTAGLANDINS | NEUROPROSTANES | B-1 | F-3-ISOPROSTANES | BIOSYNTHESIS | IN-VIVO | CHEMISTRY, ORGANIC | ISOPROSTANES | STRESS | Chemistry Techniques, Synthetic | Cyclization | Oxidation-Reduction | Stereoisomerism | Oxygen - chemistry | Cyclopentanes - chemistry | Catalysis | Cyclopentanes - chemical synthesis | Alkylation
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2017, Volume 15, Issue 44, pp. 9408 - 9414
A unified strategy for the total synthesis of the methyl esters of all phytoprostane (PhytoP) classes bearing two ring-oxygen atoms based on an orthogonally... 
Oxygen | Oxygen atoms | Precursors | Biomarkers | Esters | Chains | Chemical reactions | Cyclopentane | Coupling | Chemical synthesis
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2009, Volume 50, Issue 13, pp. 1498 - 1500
The first synthesis of 4-F -Neuroprostane 1a and its 4-epimer is described. This molecule presents an important contribution to the study of neuronal oxidative... 
Oxidative stress | Neuroprostane | Wittig | DPA | Total synthesis | HWE | Organic chemistry | Chemical Sciences
Journal Article
Plant Physiology, ISSN 0032-0889, 11/2018, Volume 178, Issue 3, pp. 1344 - 1357
The ecological success of diatoms requires a remarkable ability to survive many types of stress, including variations in temperature, light, salinity, and... 
MARINE DIATOM | PHYTOPROSTANES | NEUROPROSTANES | BIOSYNTHESIS | PLANT DEFENSE | IN-VIVO | GENE-EXPRESSION | POLYUNSATURATED FATTY-ACIDS | ALPHA-LINOLENIC ACID | LIPIDS | PLANT SCIENCES | Physiological aspects | Oxidative stress | Biosynthesis | Diatoms | Observations | Life Sciences | Biochemistry, Molecular Biology
Journal Article
by Taber, DF and Gu, PM and Li, R
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 08/2009, Volume 74, Issue 15, pp. 5516 - 5522
A stereodivergent total synthesis of the Delta(13)-9-isofurans has been developed. The four core substituted tetrahydrofurans were prepared by the Sharpless... 
SECONDARY ALCOHOLS | ISOFURANS | NEUROPROSTANES | PRODUCTS | ASYMMETRIC DIHYDROXYLATION | SELECTIVE REDUCTIONS | CHEMISTRY, ORGANIC | ISOPROSTANES | DISCOVERY | ALUMINUM-HYDRIDE | METHYL-ESTER | Furans - chemistry | Stereoisomerism | Molecular Structure
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 68, Issue 100, pp. 66 - 77
Abstract Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively females, caused in the overwhelming majority of the cases by... 
Neurology | Lipid peroxidation | Oxidative stress | Brain damage | Neurodevelopmental disorder | Murine models | Rett syndrome | F-4-NEUROPROSTANES | IRON | F-2-DIHOMO-ISOPROSTANES | NEUROSCIENCES | DEFICIENCY | CHOLESTEROL-METABOLISM | MECP2 | MOUSE MODEL | DISEASE | DYSFUNCTION | STRESS | Arachidonic Acid - metabolism | Rett Syndrome - complications | Gas Chromatography-Mass Spectrometry | Mice, Inbred C57BL | Neuroprostanes - metabolism | Oxidative Stress - physiology | Male | Mice, Transgenic | Aldehydes - metabolism | Mutation - genetics | Methyl-CpG-Binding Protein 2 - genetics | Animals | Isoprostanes - metabolism | Analysis of Variance | Nestin - genetics | Brain Injuries - blood | Female | Mice | Brain Injuries - etiology | Rett Syndrome - blood | Rett Syndrome - genetics | Brain Injuries - pathology | Disease Models, Animal | Docosahexaenoic Acids - metabolism | Models | Analysis | Protein binding | Organic chemistry | Chemical Sciences | OS, oxidative stress | Mecp2 | y, hemizygous null mice | NPBI, non-protein-bound iron | Mecp2, methyl-CpG-binding protein 2 — mouse protein | CRE, Cre-Recombinase | AdA, adrenic acid | AUs, arbitrary units | ARA, arachidonic acid | 4-HNE PAs, 4-HNE protein adducts | PSV, Preserved Speech Variant | Mecp2, methyl-CpG-binding protein 2 — mouse gene | wt, wild type | wt-Cre, wild type expressing Cre recombinase | MECP2, methyl-CpG-binding protein 2 — human gene | y, symptomatic Mecp2 308-mutated hemizygous males | ROS, reactive oxygen species | F2-IsoPs, F2-isoprostanes | MeCP2, methyl-CpG-binding protein 2 — human protein | y, Lox | F2-dihomo-IsoPs, F2-dihomo-isoprostanes | 4-HNE PAs, 4-hydroxy-2-nonenal protein adducts | Mecp2 stop | y NestinCre, rescued Lox | ASDs, autism spectrum disorders | F4-NeuroPs, F4-neuroprostanes | Mecp2 308 | stop pre-symptomatic hemizygous mice | x, symptomatic Mecp2 308-mutated females | DHA, docosahexaenoic acid | PUFAs, polyunsaturated fatty acids | BDNF, brain-derived neurotrophic factor | IsoPs, isoprostanes | RTT, Rett syndrome | stop mice (Mecp2 reactivated in the nervous tissue) | 4-HNE, 4-hydroxy-2-nonenal
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 01/2012, Volume 16, Issue 2, pp. 165 - 169
Journal Article