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Journal Article
Food Chemistry, ISSN 0308-8146, 05/2013, Volume 138, Issue 1, pp. 547 - 555
Journal Article
Critical Reviews in Analytical Chemistry, ISSN 1040-8347, 01/2018, Volume 48, Issue 1, pp. 86 - 93
Ursolic acid (UA) is a naturally occurring triterpenoid which is a promising candidate for the development of new therapeutic approaches and for the prevention... 
drug delivery systems | Ursolic acid | analytical methods | biological effects | CHEMISTRY, ANALYTICAL | NRF2 PATHWAY | BIOACTIVE TRITERPENES | OLEANOLIC ACID | MASS-SPECTROMETRY | OLEA-EUROPAEA L | PERFORMANCE LIQUID-CHROMATOGRAPHY | ANTICANCER ACTIVITY | SOLID DISPERSIONS | POLOXAMER 407 | DISSOLUTION RATE | Hypolipidemic Agents - analysis | Gas Chromatography-Mass Spectrometry | Triterpenes - pharmacology | Antineoplastic Agents, Phytogenic - analysis | Anti-Infective Agents - pharmacology | Humans | Hypoglycemic Agents - analysis | Neuroprotective Agents - analysis | Chromatography, High Pressure Liquid | Hypolipidemic Agents - pharmacology | Drug Delivery Systems | Hypoglycemic Agents - pharmacology | Triterpenes - analysis | Electrophoresis, Capillary | Animals | Neuroprotective Agents - pharmacology | Anti-Infective Agents - analysis | Antineoplastic Agents, Phytogenic - pharmacology | Biological properties | Analytical methods | Drug delivery systems | Capillary electrophoresis | Medical treatment | Mass spectroscopy | Pharmacology | Raw materials | Plants (organisms) | Drug delivery | Liquid chromatography | High-performance liquid chromatography | Chromatography | Transdermal medication | Biological materials | Gas chromatography | Biological effects | Acids | Qualitative analysis | Mass spectrometry | High performance liquid chromatography
Journal Article
Journal of Physiology and Biochemistry, ISSN 1138-7548, 11/2018, Volume 74, Issue 4, pp. 539 - 547
The link between obesity-induced systemic inflammation and decreased insulin signalling is well-known. It is also known that peripherally produced inflammatory... 
Oxidative stress | Neuroinflammation | Inflammation | Diabetes | Astrocytes | Type 3 diabetes | ACTIVATION | PHYSIOLOGY | TRIMESEMINE(TM) | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VITRO | MIDLIFE | BRAIN | MODULATION | Antioxidants - chemistry | Plant Extracts - pharmacology | Humans | Neuroprotective Agents - pharmacology | Enzyme Inhibitors - chemistry | Medicine, African Traditional | Cholinesterase Inhibitors - isolation & purification | GPI-Linked Proteins - antagonists & inhibitors | Indole Alkaloids - chemistry | Cell Survival - drug effects | Lipopolysaccharides - toxicity | Enzyme Inhibitors - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - analysis | Cholinesterase Inhibitors - analysis | Enzyme Inhibitors - analysis | Plant Extracts - isolation & purification | Enzyme Inhibitors - isolation & purification | Mesembryanthemum - chemistry | Ethnopharmacology | Cholinesterase Inhibitors - pharmacology | Antioxidants - isolation & purification | Indole Alkaloids - pharmacology | Nerve Tissue Proteins - isolation & purification | Oxidative Stress - drug effects | Acetylcholinesterase - metabolism | Astrocytes - metabolism | Plant Extracts - chemistry | Cholinesterase Inhibitors - chemistry | Nerve Tissue Proteins - analysis | Neuroprotective Agents - analysis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Monophenol Monooxygenase - antagonists & inhibitors | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Monophenol Monooxygenase - metabolism | Nerve Tissue Proteins - chemistry | Astrocytes - immunology | Nerve Tissue Proteins - pharmacology | Antioxidants - analysis | Astrocytes - drug effects | Cell Line | Neuroprotective Agents - chemistry | Cytokines - metabolism | Antioxidants - pharmacology | Drug Discovery | GPI-Linked Proteins - metabolism | Neuroprotective Agents - isolation & purification | Indole Alkaloids - analysis | Cytokines - antagonists & inhibitors | Antioxidants | Enzymes | Corticosteroids | Anti-inflammatory drugs | Physiological aspects | Polyphenols | Chronic diseases | Development and progression | Mitogens | Index Medicus
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 02/2011, Volume 19, Issue 3, pp. 1285 - 1297
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 10/2017, Volume 119, pp. 36 - 46
Journal Article
Journal of Food Science, ISSN 0022-1147, 10/2016, Volume 81, Issue 10, pp. C2439 - C2446
Journal Article
Journal of Toxicology and Environmental Health, Part A, ISSN 1528-7394, 04/2014, Volume 77, Issue 7, pp. 390 - 404
Manganese (Mn) is an essential element for human health. However, at high concentrations Mn may be neurotoxic. Mn accumulates in astrocytes, affecting their... 
ANTIOXIDANTS | AMAZONIAN PALM BERRY | DAMAGE | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | F-2-ISOPROSTANES | GLUTATHIONE | GLUTAMATE | IN-VIVO | TOXICOLOGY | DOUBLE-EDGED SWORDS | BRAIN | FRUIT PULP | Plant Extracts - chemistry | Neuroprotective Agents - analysis | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Dietary Supplements - analysis | Neuroprotective Agents - metabolism | GA-Binding Protein Transcription Factor - biosynthesis | Plant Extracts - metabolism | Anthocyanins - adverse effects | Nerve Tissue Proteins - biosynthesis | Brazil | Biological Transport - drug effects | Cerebral Cortex - drug effects | Dietary Supplements - adverse effects | Neuroprotective Agents - adverse effects | Arecaceae - chemistry | Anthocyanins - analysis | Animals, Newborn | Astrocytes - cytology | Astrocytes - drug effects | Neuroprotective Agents - chemistry | Fruit - chemistry | Manganese Poisoning - diet therapy | Cells, Cultured | Rats | Manganese - chemistry | Anthocyanins - metabolism | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Animals | Manganese Poisoning - prevention & control | Glutamic Acid - metabolism | Oxidative Stress - drug effects | Manganese - adverse effects | Astrocytes - metabolism | GA-Binding Protein Transcription Factor - metabolism | Plant Extracts - adverse effects | Antioxidants | Stresses | Stress concentration | Health | Anthocyanins | Lipids | Attenuation | Manganese
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 10/2017, Volume 14, Issue 10, pp. 3248 - 3257
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2002, Volume 81, Issue 5, pp. 1084 - 1091
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 03/2012, Volume 140, Issue 2, pp. 247 - 254
In the traditional Indian and Thai system of medicine, Linn., flower is used as brain tonic and to calm anxiety and panic attacks. The present study was... 
MCAO | Mimusops elengi | Antioxidants | Neuroprotective | Infarct volume | Brain edema | BBB disruption | HPLC | CHEMISTRY, MEDICINAL | ACID | ASSAY | TISSUE | SULFHYDRYL GROUPS | NEUROPROTECTION | PLANT SCIENCES | THERAPY | INTEGRATIVE & COMPLEMENTARY MEDICINE | ACUTE ISCHEMIC-STROKE | IMPROVES | PHARMACOLOGY & PHARMACY | MICE | Neuroprotective Agents - therapeutic use | Plant Extracts - chemistry | Reperfusion Injury - etiology | Rats, Wistar | Plant Extracts - pharmacology | Antioxidants - metabolism | Neuroprotective Agents - analysis | Polyphenols - pharmacology | Reperfusion Injury - drug therapy | Male | Chromatography, High Pressure Liquid | Flowers | Stroke - pathology | Anti-Inflammatory Agents - analysis | Neuroprotective Agents - pharmacology | Nitrites - blood | Anti-Inflammatory Agents - therapeutic use | Behavior, Animal - drug effects | Female | Phytotherapy | Ischemic Attack, Transient - metabolism | Reperfusion Injury - metabolism | Ischemic Attack, Transient - pathology | Ischemic Attack, Transient - drug therapy | Mimusops - chemistry | Cerebrovascular Disorders | Anti-Inflammatory Agents - pharmacology | Brain Edema | Rats | Stroke - drug therapy | Antioxidants - pharmacology | Blood-Brain Barrier - drug effects | Antioxidants - therapeutic use | Stroke - metabolism | Animals | Cerebral Infarction | Polyphenols - analysis | Mice | Polyphenols - therapeutic use | Plant Extracts - therapeutic use | Brain | Injuries | Edema | Neuroprotection | Stroke | Antiinflammatory agents | biomarkers | Nitrite | High-performance liquid chromatography | Stress | Neurological diseases | Reperfusion | Blood-brain barrier | Ischemia | Cerebral blood flow | Extravasation | Polyphenols | Anxiety | Brain injury
Journal Article
Drug Development Research, ISSN 0272-4391, 11/2018, Volume 79, Issue 7, pp. 339 - 351
Preclinical Research & Development Withanolide A (WA), a steroidal lactone is a major bioactive constituent of Withania somnifera (L.) with remarkable... 
pharmacokinetics | plasma protein binding | Withanolide A | LC–MS/MS | Withania somnifera | tissue distribution | WITHAFERIN-A | CHEMISTRY, MEDICINAL | QUANTIFICATION | VALIDATION | TANDEM MASS-SPECTROMETRY | BIOAVAILABILITY | PERFORMANCE LIQUID-CHROMATOGRAPHY | LC-MS/MS | IN-VITRO | PHARMACOLOGY & PHARMACY | WITHANIA-SOMNIFERA ASHWAGANDHA | HPLC | EXTRACT | Tissue Distribution - physiology | Permeability - drug effects | Tissue Distribution - drug effects | Withania | Neuroprotective Agents - analysis | Rats | Male | Lactones - analysis | Rats, Sprague-Dawley | Blood Proteins - analysis | Phytosterols - pharmacokinetics | Lactones - blood | Neuroprotective Agents - blood | Animals | Lactones - pharmacokinetics | Neuroprotective Agents - pharmacokinetics | Phytosterols - blood | Withanolides - pharmacokinetics | Phytosterols - analysis | Withanolides - blood | Withanolides - analysis | Tandem Mass Spectrometry - methods | Blood Proteins - pharmacokinetics | Protein Binding - physiology | Liquid chromatography | Permeability | Mass spectrometry | Blood proteins | Protein binding | Binding | Plasma | Neuroprotection | Chemical partition | Intravenous administration | Membrane permeability | Mass spectroscopy | Pharmacology | Blood | Chromatography | Proteins | Partitioning | Dialysis | Pharmacokinetics | Equilibrium dialysis
Journal Article