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Journal of cell science, ISSN 0021-9533, 2014, Volume 127, Issue 10, pp. 2249 - 2260
Differential kinetics of the same signaling pathway might elicit different cellular outcomes. Here, we show that high-frequency neuronal activity converts... 
Neurotrophin | Signal transduction | Neuronal activity | Signaling kinetics | Neuronal surface receptor | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Signal Transduction | Rats | Male | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Kinetics | Rats, Sprague-Dawley | Receptor, trkB - metabolism | Index Medicus
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 11/2016, Volume 100, pp. 153 - 163
... strategies that can limit the defects in, or even to restore, mitochondrial function while reducing free radical generation... 
Neuroprotection | PPARγ agonists | Mitochondrial function | Neurodegenerative disorders | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Neuroprotective Agents - therapeutic use | Humans | Alzheimer Disease - drug therapy | Mitochondria - metabolism | Parkinson Disease - drug therapy | Mitochondria - drug effects | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - drug therapy | Huntington Disease - metabolism | Amyotrophic Lateral Sclerosis - drug therapy | PPAR gamma - pharmacology | PPAR gamma - therapeutic use | Animals | Neurodegenerative Diseases - physiopathology | Neuroprotective Agents - pharmacology | Alzheimer Disease - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Parkinson Disease - metabolism | Huntington Disease - drug therapy | Mitochondria - physiology | Disease Models, Animal | Index Medicus | GSK-3β, glycogen synthase kinase-3β | BDNF, brain derived neurotrophic factor | SRC, steroid receptor coactivator | Aβ, protein amyloid-β | UCP-2, uncoupling protein 2 | Bcl-2, B-cell lymphoma2 | Review | Nrf2, nuclear factor erythroid-derived 2-like 2 | ALS, amyotrophic lateral sclerosis | HD, huntington's disease | NRF1, nuclear respiratory factor 1 | AF-1, transcriptional activation domain | LPS, lipopolysacchacaride | PPARγ, peroxisome proliferation-activated receptor gamma | UCP-1, uncoupling protein 1 | mtDNA, mitochondrial DNA | ROS, reactive oxygen species | TNFα, tumour necrosis factor α | PD, parkinson's disease | TDP-43, TAR DNA-binding protein 43 | Cdk5, cyclin-dependent kinase 5 | COX-2, cyclooxygenase-2 | PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1α | SOD1, superoxide dismutase 1 | HO-1, haem oxygenase-1 | BAT, brown adipose tissue | AD, alzheimer's disease | Bax, Bcl-2-associated X protein | TZDs, thiazolidinediones | ΔΨm, mitochondrial membrane potential | 15D-PGJ2, 15-deoxy-Δ12,14-Prostaglandin J2 | MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | CBP, CREB-binding protein | CNS, central nervous system | WAT, white adipose tissue | 6-OHDA, 6-hydroxydopamine | NF-κB, nuclear factor-κB | iNOS, inducible nitric oxide synthase | TFAM, mitochondrial transcription factor A | MPP+, 1-methyl-4-phenylpyridinium ion | NRF2, nuclear respiratory factor 2
Journal Article