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Diabetologia, ISSN 0012-186X, 2/2007, Volume 50, Issue 2, pp. 431 - 438
Journal Article
Experimental Cell Research, ISSN 0014-4827, 03/2019, Volume 376, Issue 2, pp. 221 - 226
Over the last decade there has been growing evidence that Brain Expressed X-Linked 2 (BEX2) has a significant role in the process of carcinogenesis.... 
Brain tumor | NF-κB | BEX2 | Breast cancer | Oncogene | JNK | SURVIVAL | TARGET | APOPTOSIS | NEUROTROPHIN RECEPTOR | CELL-CYCLE ARREST | PROLIFERATION | PP2A | NERVE GROWTH-FACTOR | CELL BIOLOGY | BREAST-CANCER | NF-kappa B | ONCOLOGY | GENE FAMILY | Proteins | Gliomas | Leukemia | Genes | Brain tumors | Colorectal cancer | Development and progression | Nerve growth factor | Gene expression | Health aspects
Journal Article
Traffic, ISSN 1398-9219, 11/2011, Volume 12, Issue 11, pp. 1620 - 1633
Dynamin (Dyn) is a multidomain and multifunctional GTPase best known for its essential role in clathrin‐mediated endocytosis (CME). Dyn2 mutations have been... 
p75/neurotrophin receptor | centronuclear myopathy | lipid rafts | Charcot‐Marie‐Tooth disease | EGFR | clathrin‐mediated endocytosis | Centronuclear myopathy | Lipid rafts | Clathrin-mediated endocytosis | Charcot-Marie-Tooth disease | Receptor, Epidermal Growth Factor - genetics | Receptor, Nerve Growth Factor - genetics | Humans | Myopathies, Structural, Congenital - genetics | Charcot-Marie-Tooth Disease - genetics | Receptor, Epidermal Growth Factor - metabolism | Dynamin II - metabolism | Endocytosis - genetics | Muscles - metabolism | Charcot-Marie-Tooth Disease - metabolism | Receptor, Nerve Growth Factor - metabolism | Cell Line | Cholera Toxin - metabolism | Dynamin II - genetics | Clathrin - genetics | Clathrin - metabolism | Endocytosis - physiology | Mice, Knockout | Protein Transport | Homozygote | Phenotype | Animals | Cholera Toxin - genetics | Golgi Apparatus - metabolism | Heterozygote | Mice | Myopathies, Structural, Congenital - metabolism | Mutation | Golgi Apparatus - genetics | GTPASE ACTIVITY | MARIE-TOOTH-DISEASE | TRANSPORT VESICLES | PLASMA-MEMBRANE | COATED VESICLE FORMATION | clathrin-mediated endocytosis | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | PLECKSTRIN HOMOLOGY DOMAIN | T-TUBULE | Physiological aspects | Embryonic development | Genetic aspects | Epidermal growth factor | Cholera toxin | Centronuclear Myopathy | neurotrophin receptor | EGF receptor | p75
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3541 - 3551
Nerve growth factor (NGF) contributes to the development of chronic pain associated with degenerative connective tissue pathologies, such as intervertebral... 
pain | intervertebral disc | FIBRONECTIN FRAGMENT | LOW-BACK-PAIN | C-FOS | low back pain | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | NF-B (NF-KB) | MESSENGER-RNA | nerve growth factor | NGF SYNTHESIS | nucleus pulposus | IN-VIVO | GENE-EXPRESSION | neurotrophin | toll-like receptor (TLR) | TNF-ALPHA | Nerve Growth Factor - secretion | Intervertebral Disc - cytology | Toll-Like Receptor 2 - agonists | Toll-Like Receptor 2 - antagonists & inhibitors | Toll-Like Receptor 2 - genetics | Transcription Factor RelA - antagonists & inhibitors | Humans | Middle Aged | Antibodies, Neutralizing - metabolism | Protein Precursors - secretion | Male | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Young Adult | Interleukin-1beta - metabolism | Adult | Female | Interleukin-1beta - antagonists & inhibitors | Interleukin-1beta - secretion | Recombinant Proteins - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Growth Factor - metabolism | Protein Precursors - genetics | Nerve Tissue Proteins - agonists | Cells, Cultured | Recombinant Proteins - chemistry | Nerve Growth Factor - genetics | Intervertebral Disc - metabolism | Toll-Like Receptor 2 - metabolism | Nerve Tissue Proteins - genetics | Protein Precursors - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | MAP Kinase Signaling System - drug effects | Transcription Factor RelA - metabolism | Active Transport, Cell Nucleus - drug effects | Adolescent | Ligands | Intervertebral Disc - drug effects | Protein Kinase Inhibitors - pharmacology | Lumbar Vertebrae | Tissue Donors | NF-κB (NF-KB) | Cell Biology
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 11/2016, Volume 25, Issue 22, pp. 4920 - 4938
Decreases in the ratio of neurotrophic versus neurodegenerative signalling play a critical role in Huntington's disease (HD) pathogenesis and recent evidence... 
NEURONAL INTRANUCLEAR INCLUSIONS | DENDRITIC SPINES | NERVOUS-SYSTEM | P75 NEUROTROPHIN RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | MUTANT HUNTINGTIN | GENETICS & HEREDITY | STRIATAL SPINY NEURONS | NF-KAPPA-B | TRANSGENIC MICE | COGNITIVE DEFICITS
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2017, Volume 13, Issue 8, p. e1006968
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 02/2017, Volume 639, pp. 88 - 93
In the mouse cerebellum, Ca -dependent activator protein for secretion 2 (CADPS2, CAPS2) is involved in regulated secretion from dense-core vesicles (DCVs),... 
Neurotrophin | Autism | KEGG | Cadps2 | GeneChip | Secretion | EXOCYTOSIS | MOUSE | CELL-SURVIVAL | NEUROSCIENCES | NERVE GROWTH-FACTOR | MICE | DENSE-CORE VESICLES | NEUROTROPHIN RELEASE | BRAIN | CAPS2
Journal Article
Journal of Alzheimer's disease : JAD, ISSN 1387-2877, 2018, Volume 63, Issue 1, pp. 139 - 147
Journal Article