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The Journal of Nutritional Biochemistry, ISSN 0955-2863, 07/2016, Volume 33, pp. 8 - 14
Lipopolysaccharide (LPS) is the major structural component of Gram-negative bacteria cell wall and a highly pro-inflammatory toxin. Naringenin is found in... 
Oxidative stress | NF-κB | Cytokines | Leukocyte recruitment | Inflammatory pain | HAIRLESS MICE | TOPICAL FORMULATIONS | ANTIBIOTICS | NOCICEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | SENSORY NEURONS | NUTRITION & DIETETICS | NF-kappa B | CYTOKINE PRODUCTION | INDUCED OXIDATIVE STRESS | HYPERALGESIA | BACTERIOLYSIS | Leukocytes, Mononuclear - metabolism | Transcription Factor RelA - antagonists & inhibitors | Skin - metabolism | Stress, Mechanical | Male | Behavior, Animal | Leukocytes, Mononuclear - immunology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Neutrophils - metabolism | Macrophages - immunology | Neutrophil Infiltration - drug effects | Skin - immunology | Biomarkers - metabolism | Leukocytes, Mononuclear - drug effects | Lipopolysaccharides - toxicity | Flavanones - therapeutic use | Hot Temperature - adverse effects | Hyperalgesia - metabolism | Neutrophils - drug effects | Neutrophils - immunology | Hyperalgesia - prevention & control | Hyperalgesia - immunology | Antioxidants - therapeutic use | Macrophages - metabolism | Animals | Transcription Factor RelA - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Flavanones - metabolism | Macrophages - drug effects | RAW 264.7 Cells | Mice | Oxidative Stress - drug effects | Macrophage Activation - drug effects | Dietary Supplements | Skin - drug effects | Index Medicus
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2013, Volume 14, Issue 1, pp. 41 - 51
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 03/2014, Volume 275, Issue 2, pp. 122 - 133
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2016, Volume 311, Issue 3, pp. H725 - H734
Platelets are capable of binding, aggregating, and internalizing microorganisms, which enhances the elimination of pathogens from the blood. The yeast Candida... 
Aggregation | Candida albicans | Tolllike receptors | β-Glucans | Platelets | Coagulation | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | beta-glucans | toll-like receptors | RECOGNITION | INFLAMMATORY RESPONSES | THROMBOSIS | MACROPHAGES | RECEPTOR | aggregation | OLIGOSACCHARIDE | coagulation | SACCHAROMYCES-CEREVISIAE | platelets | TUMOR-NECROSIS-FACTOR | CANDIDA-ALBICANS | POLYSACCHARIDES | PERIPHERAL VASCULAR DISEASE | Up-Regulation | Phosphorylation | P-Selectin - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Platelet Glycoprotein GPIIb-IIIa Complex - drug effects | Protein Kinase C - metabolism | Adenosine Triphosphate - metabolism | Platelet Glycoprotein GPIIb-IIIa Complex - metabolism | Transforming Growth Factor beta1 - drug effects | Platelet Aggregation - drug effects | Toll-Like Receptor 4 - antagonists & inhibitors | Blood Platelets - drug effects | Real-Time Polymerase Chain Reaction | Thrombin - drug effects | Fibrinogen - drug effects | Glucosides - pharmacology | Protein Kinase C - drug effects | Neutrophils | Fungi - chemistry | beta-Glucans - pharmacology | Toll-Like Receptor 4 - metabolism | Platelet Adhesiveness - drug effects | P-Selectin - drug effects | Blood Platelets - metabolism | Fibrinogen - metabolism | Platelet Activation - drug effects | Thrombin - metabolism | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 174 - 184
Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear.... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | INTERLEUKIN-18 LEVELS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOVASCULAR-DISEASE | RECEPTOR | ESSENTIAL-HYPERTENSION | PROTEINS | T-CELLS | AGE | CELL BIOLOGY | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Oxidative Stress - immunology | Transcriptome | Immunoblotting | Male | Purinergic P1 Receptor Antagonists - pharmacology | Young Adult | Toll-Like Receptor 8 - immunology | Aging - immunology | Toll-Like Receptor 6 - immunology | Aging - genetics | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Aged, 80 and over | Caffeine - pharmacology | Hypertension - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin 1 Receptor Antagonist Protein - immunology | Carotid Intima-Media Thickness | Mortality | Neutrophils - drug effects | Hypertension - immunology | Nucleotides - metabolism | Toll-Like Receptor 5 - immunology | Monocytes - drug effects | Regression Analysis | Phenotype | Mice | Calcium-Binding Proteins - genetics | Metabolomics | Pulse Wave Analysis | Neutrophil Activation - drug effects | Cytidine - pharmacology | Interleukin 1 Receptor Antagonist Protein - genetics | Intracellular Signaling Peptides and Proteins - immunology | Cytidine - analogs & derivatives | CARD Signaling Adaptor Proteins - genetics | Toll-Like Receptor 6 - genetics | Adult | Female | Blood Pressure - drug effects | Blood Platelets - drug effects | Macrophages - immunology | Cytokines - immunology | CARD Signaling Adaptor Proteins - immunology | Cell Line | Vascular Stiffness - genetics | Cytokines - metabolism | Oxidative Stress - genetics | Interleukin-1beta - immunology | Adenine - pharmacology | Inflammation - immunology | Inflammasomes - genetics | Vascular Stiffness - immunology | Animals | Inflammasomes - immunology | Toll-Like Receptor 8 - genetics | Inflammation - genetics | Aged | Platelet Activation - drug effects | Genetic aspects | Immune response | Gene expression | Health aspects | Aging | Inflammation | Immune system | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2006, Volume 116, Issue 12, pp. 3211 - 3219
Journal Article
Nature Communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, pp. 11037 - 11037
Excessive activation of blood coagulation and neutrophil accumulation have been described in several human cancers. However, whether hypercoagulation and... 
COLON-CANCER | COMPLEMENT | ACTIVATION | RISK-FACTORS | VENOUS THROMBOEMBOLISM | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MOLECULAR-WEIGHT HEPARIN | MOUSE MODEL | EXTRACELLULAR DNA TRAPS | TISSUE FACTOR | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2007, Volume 176, Issue 2, pp. 231 - 241
Neutrophil extracellular traps (NETs) are extracellular structures composed of chromatin and granule proteins that bind and kill microorganisms. We show that... 
Oxidases | Chromatin | Cell death | Antimicrobials | Cell nucleus | Neutrophils | Nuclear membrane | Cell membranes | Neuroendocrine tumors | Apoptosis | STREPTOCOCCUS | APOPTOSIS | ACTIVATION | MYELOPEROXIDASE | REACTIVE OXYGEN | LEUKOCYTES | CHRONIC GRANULOMATOUS-DISEASE | AUTOTOXICITY | STAPHYLOCOCCUS-AUREUS | HYDROGEN-PEROXIDE | CELL BIOLOGY | Catalase - pharmacology | Leukocyte Elastase - metabolism | Chromatin - metabolism | Neutrophils - cytology | Vacuoles - ultrastructure | Reactive Oxygen Species - metabolism | Tetradecanoylphorbol Acetate - pharmacology | Apoptosis - drug effects | Staphylococcus aureus - physiology | Catalase - antagonists & inhibitors | Humans | Cell Death - immunology | Granulomatous Disease, Chronic - metabolism | Neutrophil Activation - drug effects | Nuclear Envelope - ultrastructure | fas Receptor - immunology | Immunity, Innate - physiology | Cytoplasmic Granules - metabolism | Cell Death - drug effects | Neutrophils - microbiology | Granulomatous Disease, Chronic - pathology | Cell Survival - physiology | Cell Survival - drug effects | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Neutrophils - physiology | Phagocytosis - immunology | Onium Compounds - pharmacology | Cell Survival - immunology | Microscopy, Electron | Neutrophil Activation - physiology | Antibodies - pharmacology | Nuclear Envelope - metabolism | Apoptosis - immunology | Cell Death - physiology | Cytoplasmic Granules - ultrastructure | Vacuoles - metabolism | Apoptosis - physiology | Heterochromatin | Index Medicus
Journal Article