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The Journal of experimental medicine, ISSN 0022-1007, 07/2017, Volume 214, Issue 7, pp. 2103 - 2119
Neutrophils play a crucial role in host defense. However, neutrophil activation is also linked to autoimmune diseases such as systemic lupus erythematosus (SLE... 
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Extracellular Traps - metabolism | Dendritic Cells - immunology | Humans | Complement C5a - metabolism | Lupus Erythematosus, Systemic - metabolism | Monocytes - metabolism | Monocytes - immunology | Complement Activation - immunology | Receptors, IgG - metabolism | Toll-Like Receptor 8 - immunology | Extracellular Traps - immunology | Flow Cytometry | Toll-Like Receptor 7 - immunology | Lupus Erythematosus, Systemic - immunology | Neutrophils - metabolism | Dendritic Cells - metabolism | Toll-Like Receptor 7 - metabolism | Cells, Cultured | Neutrophils - immunology | Phagocytosis - immunology | Receptors, IgG - immunology | Blotting, Western | Complement C5a - immunology | Antigen-Antibody Complex - immunology | Toll-Like Receptor 8 - metabolism | Shedding | Complement component C5a | Immune clearance | Proteins | Cell activation | Systemic lupus erythematosus | Proteolysis | Toll-like receptors | Furin | Cleavage | Antigen-antibody complexes | Immune system | TLR7 protein | Dendritic cells | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Nucleic acids | Signaling | Monocytes | Chronic conditions | Complement activation | Information processing | Autoimmune diseases | Phagocytosis | Index Medicus | 311 | 300 | Extracellular Traps/immunology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Phagocytosis/immunology | Immunologi inom det medicinska området | Lupus Erythematosus, Systemic/immunology | Toll-Like Receptor 7/immunology | Neutrophils/immunology | Complement Activation/immunology | Monocytes/immunology | Antigen-Antibody Complex/immunology | Receptors, IgG/immunology | Medicinska och farmaceutiska grundvetenskaper | Dendritic Cells/immunology | Complement C5a/immunology | Toll-Like Receptor 8/immunology | Immunology in the medical area
Journal Article
Infection and immunity, ISSN 1098-5522, 03/2014, Volume 82, Issue 3, pp. 937 - 948
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1424 - 1432
.... Platelet-activating factor (PAF) is a potent phospholipid-derived mediator the central role of which has been well established in experimental models of both immune-mediated and non... 
Allergy and Immunology | Allergy | signaling | mediators | receptor antagonists | anaphylaxis | platelet-activating factor | mast cells | acetylhydrolase | platelets | sepsis | Immunology | Life Sciences & Biomedicine | Science & Technology | Blood Platelets - pathology | Blood Platelets - immunology | Humans | Platelet Activation - immunology | Platelet Activating Factor - immunology | Eosinophils - immunology | 1-Alkyl-2-acetylglycerophosphocholine Esterase - immunology | Receptors, G-Protein-Coupled - immunology | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Sepsis - pathology | Asthma - immunology | Anaphylaxis - immunology | Eosinophils - pathology | Platelet Aggregation - genetics | Neutrophils - pathology | Mast Cells - immunology | Platelet Membrane Glycoproteins - immunology | Sepsis - immunology | Platelet Aggregation - immunology | Signal Transduction | Anaphylaxis - pathology | Gene Expression Regulation | Neutrophils - immunology | Platelet Activating Factor - genetics | Platelet Membrane Glycoproteins - genetics | Asthma - genetics | Sepsis - genetics | Anaphylaxis - genetics | Platelet Activation - genetics | Mast Cells - pathology | Receptors, G-Protein-Coupled - genetics | Asthma - pathology | Enzymes | Immune response | Anaphylaxis | Permeability | Metabolites | Analysis | Proteins | Antigens | Blood platelets | E coli | Rodents | Preeclampsia | Lipids | Smooth muscle | Carbon | Biological activity | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 11/2017, Volume 114, Issue 45, pp. E9618 - E9625
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) constitutes life-threatening autoimmune diseases affecting every organ, including the... 
Glomerulonephritis | NETs | Complement | ANCA | Necroptosis | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Cell Line | Neutrophil Activation - immunology | Humans | Kidney - immunology | Neutrophils - immunology | Male | Necrosis - metabolism | Complement Activation - immunology | Antibodies, Antineutrophil Cytoplasmic - immunology | Necrosis - immunology | Endothelial Cells - immunology | Kidney - metabolism | Animals | Apoptosis - immunology | Extracellular Traps - immunology | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology | Complement Pathway, Alternative - immunology | Female | Mice | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - metabolism | Physiological aspects | Vasculitis | Health aspects | Apoptosis | Animal models | Syngeneic grafts | Complement component C5a | Clinical trials | Cardiovascular disease | Kinases | Damage prevention | Cell activation | Antineutrophil cytoplasmic antibodies | Bone marrow | Inhibition | Medical research | Damage assessment | Kidneys | Medical treatment | Neutrophils | MAP kinase | Leukocytes (neutrophilic) | Pharmacology | Endothelial cells | Endothelium | Complement activation | Protein kinase | Autoimmune diseases | Index Medicus | Biological Sciences | PNAS Plus | complement | glomerulonephritis | necroptosis
Journal Article
PloS one, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e53531 - e53531
...), is a potent adjuvant inducing strong Th1 and Th17 immune responses. We previously identified the C-type lectin Mincle as receptor for these glycolipids that triggers the FcR gamma-Syk-Card9 pathway for APC activation and adjuvanticity... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adjuvants, Immunologic - administration & dosage | Cytoskeletal Proteins - genetics | Receptors, Interleukin-1 - genetics | Antigens, Bacterial - immunology | Interleukin-17 - immunology | Lectins, C-Type - immunology | Lectins, C-Type - genetics | Th1 Cells - immunology | Cytoskeletal Proteins - deficiency | Membrane Proteins - deficiency | Molecular Mimicry | Adjuvants, Immunologic - chemistry | Myeloid Differentiation Factor 88 - immunology | Interferon-gamma - genetics | Lectins, C-Type - deficiency | Tuberculosis Vaccines - immunology | Adaptive Immunity | Immunization | Vaccines, Subunit | Antigens, Bacterial - chemistry | Signal Transduction | Membrane Proteins - genetics | Receptors, Interleukin-1 - immunology | Cord Factors - chemistry | Tuberculosis Vaccines - administration & dosage | Gene Expression Regulation | Myeloid Differentiation Factor 88 - genetics | Interleukin-17 - genetics | Membrane Proteins - immunology | Cord Factors - immunology | Mice, Knockout | Tuberculosis - immunology | Animals | Apoptosis Regulatory Proteins | Cytoskeletal Proteins - immunology | Tuberculosis Vaccines - chemistry | CARD Signaling Adaptor Proteins | Interferon-gamma - immunology | Tuberculosis - prevention & control | Th17 Cells - immunology | Mice | Lectins | Antigens | Membrane lipids | Tuberculosis vaccines | Plant lipids | Vaccination | Trehalose | Helper cells | Intracellular signalling | Activation | Lymphocytes T | Interleukin 1 receptors | Cord factor | Experiments | Signal transduction | Immunology | Lymphocytes | Interleukin 1 | Immunoglobulins | Immune response | Cytokines | Neutrophils | Adjuvanticity | Interleukin 17 | Interleukin 18 | Infectious diseases | Hospitals | Tuberculosis | Glycolipids | Antigen-presenting cells | γ-Interferon | MyD88 protein | Syk protein | Hygiene | Index Medicus
Journal Article