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Autophagy, ISSN 1554-8627, 07/2015, Volume 11, Issue 7, pp. 1063 - 1080
Oxidative stress (OS) stimulates autophagy in different cellular systems, but it remains controversial if this rule can be generalized. We have analyzed the... 
NQO2 | paraquat | astrocytes | parkinson disease | macroautophagy | ROS | Parkinson disease | Paraquat | Astrocytes | Macroautophagy | DMSO | autophagic vacuoles | 6 dihydro-6-phenyl | phosphate-buffered saline | CELL BIOLOGY | PARAQUAT-INDUCED AUTOPHAGY | shRNA | short harpin ribonucleic acid | flow cytometry | NMDPEF | PBS | mean fluorescence intensity | antibody | 8-phenanthridinediamine | GLIAL INCLUSIONS | phosphorylated | MAPK | green fluorescent protein | Dulbecco's modified Eagle's medium | nuclear factor | CELL-DEATH | TRANSCRIPTION FACTOR NRF2 | small interfering ribonucleic acid | N-[2-(2-methoxy-6H-dipyrido[2,3-a:3,2-e]pyrrolizin-11-yl)ethyl]-2-furamide | glial fibrillary acidic protein | 1-methyl 4-phenyl 1 | erythroid 2-like 2 | room temperature | PROTEIN AGGREGATION | FACS | NEUROBLASTOMA-CELLS | 5-carboxy-2 | chloroquine | GFP | mitogen-activated protein kinase | benzyldihydronicotinamide riboside | DMEM | MFI | IN-VITRO | dimethyl sulfoxide | reactive oxygen species | CA-DCF-DA | HYDROGEN-PEROXIDE TOXICITY | AVs | QUINONE REDUCTASE | 5-(6-triphenylphosphoniumhexyl)-5 | substantia nigra | OXYGEN SPECIES PRODUCTION | 7 dichlorofluorescein diacetate | MitoSOX | siRNA | western blotting | BNAH | GFAP | 6-tetraidro-piridine | menadione | TTBS | MPTP | Tween-Tris buffered saline | oxidative stress | NFE2L2 | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Astrocytes - pathology | Astrocytes - enzymology | Vacuoles - drug effects | Autophagy - drug effects | Neuroprotection - drug effects | Astrocytoma - pathology | Neuroprotective Agents - pharmacology | Formamides - pharmacology | Phagosomes - drug effects | Astrocytes - drug effects | Quinone Reductases - metabolism | Parkinson Disease - pathology | Phagosomes - metabolism | Enzyme Inhibitors - pharmacology | Neurotoxins - toxicity | Antioxidants - pharmacology | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Acetylcysteine - pharmacology | Vacuoles - metabolism | Benzhydryl Compounds - pharmacology | Mice | Oxidative Stress - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Paraquat - toxicity | Index Medicus
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 09/2011, Volume 25, Issue 5, pp. 320 - 329
Chemicals that activate nuclear factor‐E2‐related factor 2 (Nrf2) often increase multidrug‐resistance‐associated protein (Mrp) expression in liver.... 
Nuclear Factor‐E2‐Related Factor 2(nrfz | Kelch‐Like ECH‐Associated Protein 1(Kea‐p1) | nfe2Lz) Organic Anion‐Transporting Polypeptide (Oatp | Abcc4 | Multidrug‐Resistance‐Associated Protein(Mrp) | Kelch-Like ECH-Associated Protein 1(Kea-p1) | Nfe2Lz) Organic Anion-Transporting Polypeptide (Oatp | Multidrug-Resistance-Associated Protein(Mrp) | Nuclear Factor-E2-Related Factor 2(nrfz | Nuclear Factor-E2-Related Factor 2(nrfz, nfe2Lz) Organic Anion-Transporting Polypeptide (Oatp) | DIFFERENTIAL EXPRESSION | Kelch-Like ECH-Associated Protein 1(Keap1) | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE-LIVER | TRANSCRIPTION FACTOR NRF2 | ANTIOXIDANT RESPONSE ELEMENT | TRANS-STILBENE OXIDE | TISSUE DISTRIBUTION | IN-VIVO | ANDROSTANE RECEPTOR | GENE-EXPRESSION | RESISTANCE | TOXICOLOGY | Cytoskeletal Proteins - genetics | Cytochrome P-450 Enzyme System - metabolism | Hepatocytes - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Organic Anion Transporters - metabolism | Cytoskeletal Proteins - deficiency | Hepatocytes - cytology | Organic Anion Transporters - genetics | Gene Deletion | Multidrug Resistance-Associated Proteins - genetics | NF-E2-Related Factor 2 - genetics | Glutamate-Cysteine Ligase - metabolism | Kelch-Like ECH-Associated Protein 1 | Drug Resistance, Multiple - genetics | Signal Transduction | Liver - metabolism | Gene Expression Regulation | Mice, Knockout | Animals | Adaptor Proteins, Signal Transducing - deficiency | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Cytochrome P-450 Enzyme System - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Glutamate-Cysteine Ligase - genetics | Liver - cytology | Mice | Multidrug Resistance-Associated Proteins - metabolism | Glutamate-cysteine ligase | Enzymes | biotransformation | organic anion transporting polypeptide | Cytochrome P450 | Liver | Sulfotransferase | mRNA | Internet | Gene expression | oxidoreductase | Catalytic subunits | Index Medicus | Multidrug resistance-associated protein (Mrp) | Keap1 | nfe2l2 | Organic anion transporting polypeptide (Oatp) | Nrf2
Journal Article
Journal Article
The Journal of Reproduction and Development, ISSN 0916-8818, 01/2019, Volume 65, Issue 1, p. 73
Pterostilbene (PTS) in blueberries is a phytoalexin with antioxidant properties. PTS exerts strong cytoprotective effects on various cells via Nuclear Factor... 
Cell culture | Oxidative stress | Reactive oxygen species | Media (culture) | Hydrogen peroxide | Bax protein | Bcl-2 protein | Superoxide dismutase | Caspase-3 | Antioxidants | Proteins | Signal transduction | Catalase | Heme | Peroxidase | Glutathione | Glutathione peroxidase | Caspase | Blastocysts | Embryos | Lymphoma | Zygotes | Lymphocytes B | Protein expression | X protein | Apoptosis | B-cell lymphoma
Journal Article
Redox Biology, ISSN 2213-2317, 04/2017, Volume 11, Issue C, pp. 254 - 262
Artesunate, an anti-malarial drug, has been repurposed as an anticancer drug due to its induction of cell death reactive oxygen species (ROS) production.... 
Resistance | Head and neck cancer | Ferroptosis | Reactive oxygen species | Nrf2 | Artensunate | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | MECHANISMS | MEDIATED APOPTOSIS | DRUG-RESISTANCE | PROTECTS | IN-VITRO | ENHANCEMENT | RADIOTHERAPY | ARTEMISININ | CYTOTOXICITY | Heme Oxygenase-1 - metabolism | NF-E2-Related Factor 2 - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Head and Neck Neoplasms - metabolism | Reactive Oxygen Species - agonists | Kelch-Like ECH-Associated Protein 1 - genetics | Artemisinins - antagonists & inhibitors | Heme Oxygenase-1 - genetics | Artemisinins - pharmacology | Chromans - pharmacology | Cyclohexylamines - pharmacology | NF-E2-Related Factor 2 - genetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Alkaloids - pharmacology | Signal Transduction | Membrane Proteins - genetics | Head and Neck Neoplasms - drug therapy | Kelch-Like ECH-Associated Protein 1 - metabolism | Cisplatin - pharmacology | Drug Repositioning | Iron - metabolism | Antimalarials - pharmacology | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Mice, Nude | NF-E2-Related Factor 2 - metabolism | Head and Neck Neoplasms - genetics | Phenylenediamines - pharmacology | Mice | Mice, Inbred BALB C | Apoptosis | Drug Resistance, Neoplasm - drug effects | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 41, pp. 28660 - 28675
The cadmium-transformed human lung bronchial epithelial BEAS-2B cells exhibit a property of apoptosis resistance as compared with normal non-transformed... 
TARGET | OVEREXPRESSION | BCL-2 | OXIDATIVE STRESS | ACTIVATION | TRANSCRIPTION FACTOR NRF2 | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | AUTOPHAGY | P62 | BINDING | Neoplasm Transplantation | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | NF-E2-Related Factor 2 - antagonists & inhibitors | Superoxide Dismutase - genetics | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Epithelial Cells - drug effects | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | bcl-X Protein - genetics | Apoptosis - genetics | Lung Neoplasms - pathology | Male | Cell Transformation, Neoplastic - chemically induced | Green Fluorescent Proteins - genetics | Bronchi - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cell Transformation, Neoplastic - genetics | Bronchi - metabolism | NF-E2-Related Factor 2 - genetics | Autophagy - genetics | Bronchi - pathology | Genes, Reporter | Superoxide Dismutase - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Lung Neoplasms - genetics | Cell Line | Green Fluorescent Proteins - metabolism | Cadmium - toxicity | Signal Transduction | Catalase - genetics | Epithelial Cells - pathology | Cell Transformation, Neoplastic - metabolism | Catalase - metabolism | Animals | Mice, Nude | NF-E2-Related Factor 2 - metabolism | Mice | Cell Transformation, Neoplastic - pathology | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Cadmium | Reactive Oxygen Species (ROS) | Nuclear Factor 2 (Erythroid-derived 2-like Factor) (NFE2L2) (Nrf2) | Autophagy | Carcinogenesis | p62 | Cell Biology | Apoptosis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2014, Volume 289, Issue 36, pp. 24944 - 24955
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 15, pp. 9738 - 9752
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 07/2012, Volume 21, Issue 14, pp. 3173 - 3192
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 1, pp. 327 - 340
Mutations in the genes encoding nuclear factor (erythroid-derived 2)-like 2 (NRF2), Kelch-like ECH-associated protein 1 (KEAP1), and cullin 3 (CUL3) are... 
SURVIVAL | Nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2) | PROTEIN | proliferation | PKM2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | pentose phosphate pathway (PPP) | ISOFORM | IDENTIFICATION | Esophagus | LUNG-CANCER | PYRUVATE-KINASE | SIGNALING PATHWAY | Keap1 | CANCER METABOLISM | metabolism | epithelium | BINDING-SITES | Index Medicus
Journal Article
Cell and Bioscience, ISSN 2045-3701, 08/2014, Volume 4, Issue 1, pp. 39 - 39
Nrf2 plays a critical role in defending against oxidative stress and inflammation. We previously reported that Nrf2 confers protection against ultraviolet-B... 
MIP-2 | pro-MMP-9 | Inflammation | Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or Nrf2) | Ultraviolet | ECM | p53 | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KERATINOCYTES | METALLOPROTEINASES | CANCER | RESPONSES | EPIDERMIS | DEFICIENT | CYTOPROTECTION | MICE | EXPRESSION | Skin | Comparative analysis | Tumor proteins | DNA damage
Journal Article
Journal of Reproduction and Development, ISSN 0916-8818, 2018
Pterostilbene (PTS) in blueberries is a phytoalexin with antioxidant properties. PTS exerts strong cytoprotective effects on various cells via Nuclear Factor... 
Oxidative stress | In vitro culture medium | Mouse embryo | Nuclear Factor Erythroid 2 like 2 (NFE2L2) | Pterostilbene
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2017, Volume 292, Issue 1, pp. 205 - 216
Journal Article
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