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Drug safety, ISSN 0114-5916, 2005, Volume 28, Issue 3, pp. 263 - 275
Background: Drug-drug interactions (DDIs) are a well known risk factor for adverse drug reactions. HMG-CoA reductase inhibitors (`statins') are a cornerstone... 
HMG CoA reductase inhibitors | Drug interactions | Lipid metabolism disorders | Medicine & Public Health | Drug Safety and Pharmacovigilance | Pharmacology/Toxicology | Pharmacology & Pharmacy | Public, Environmental & Occupational Health | Toxicology | Life Sciences & Biomedicine | Science & Technology | Digoxin - adverse effects | Oxidoreductases, N-Demethylating - administration & dosage | Prevalence | Simvastatin - adverse effects | Cytochrome P-450 CYP3A | Humans | Male | Drug Monitoring - methods | Heptanoic Acids - adverse effects | Drug Interactions | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Time Factors | Aryl Hydrocarbon Hydroxylases - adverse effects | Fatty Acids, Monounsaturated - adverse effects | Niacin - adverse effects | Pyrroles - adverse effects | Oxidoreductases, N-Demethylating - adverse effects | Product Surveillance, Postmarketing - methods | Pravastatin - therapeutic use | Comorbidity | Pravastatin - metabolism | Simvastatin - metabolism | Niacin - metabolism | Cyclosporine - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Indoles - adverse effects | Cyclosporine - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Indoles - therapeutic use | Simvastatin - therapeutic use | Heptanoic Acids - metabolism | Digoxin - metabolism | Heptanoic Acids - therapeutic use | Physicians - classification | Hyperlipidemias - diagnosis | Hyperlipidemias - epidemiology | Indoles - metabolism | Fatty Acids, Monounsaturated - therapeutic use | Niacin - therapeutic use | Fatty Acids, Monounsaturated - metabolism | Pravastatin - adverse effects | Female | Drug Therapy, Combination | Pyrroles - therapeutic use | Cyclosporine - metabolism | Digoxin - therapeutic use | Physicians - statistics & numerical data | Pyrroles - metabolism | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cross-Sectional Studies | Hyperlipidemias - drug therapy | Ambulatory Care | Atorvastatin Calcium | Aged | Aryl Hydrocarbon Hydroxylases - administration & dosage | Index Medicus
Journal Article
Nature reviews. Drug discovery, ISSN 1474-1784, 05/2014, Volume 13, Issue 6, pp. 445 - 464
...) are inversely associated with cardiovascular outcome, it has been postulated that HDL is anti-atherogenic and that increasing HDL-C levels is a promising therapeutic strategy... 
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cholesterol Ester Transfer Proteins - antagonists & inhibitors | Recombinant Proteins - therapeutic use | Drugs, Investigational - adverse effects | Lipoproteins, HDL - agonists | Hypolipidemic Agents - metabolism | Lipoproteins, HDL - blood | Cardiovascular Diseases - prevention & control | Humans | Lipoproteins, HDL - metabolism | Drugs, Investigational - therapeutic use | Drugs, Investigational - metabolism | Recombinant Proteins - adverse effects | Phosphatidylcholine-Sterol O-Acyltransferase - genetics | Apolipoprotein A-I - genetics | Niacin - therapeutic use | Cardiovascular Diseases - blood | Lipoproteins, HDL - therapeutic use | Niacin - adverse effects | Recombinant Proteins - metabolism | Hypolipidemic Agents - adverse effects | Molecular Targeted Therapy - adverse effects | Cardiovascular Diseases - metabolism | Clinical Trials as Topic | Apolipoprotein A-I - metabolism | Apolipoprotein A-I - agonists | Niacin - metabolism | Up-Regulation - drug effects | Phosphatidylcholine-Sterol O-Acyltransferase - adverse effects | Animals | Models, Biological | Phosphatidylcholine-Sterol O-Acyltransferase - therapeutic use | Hypolipidemic Agents - therapeutic use | Cholesterol Ester Transfer Proteins - metabolism | Phosphatidylcholine-Sterol O-Acyltransferase - metabolism | Care and treatment | High density lipoproteins | Patient outcomes | Development and progression | Research | Cardiovascular diseases | Risk factors | Index Medicus
Journal Article