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Current Medicinal Chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 16, pp. 1 - 16
The old-fashioned anticancer approaches, aiming at arresting cancer cell proliferation interfering with non-specific targets (e.g. DNA), have been replaced, in... 
Tumor microenvironment | Fda-Approved drugs | Multitargeted drugs | Anticancer agents | Polypharmacology | Tyrosine kinase receptors | Oncogene addiction | CHRONIC MYELOGENOUS LEUKEMIA | CHEMISTRY, MEDICINAL | GROWTH-FACTOR-RECEPTOR | TARGETED-THERAPY | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGORAFENIB BAY 73-4506 | BCR-ABL INHIBITOR | anticancer agents | FDA-approved drugs | CELL LUNG-CANCER | tyrosine kinase receptors | oncogene addiction | polypharmacology | PHILADELPHIA-CHROMOSOME | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | tumor microenvironment | GASTROINTESTINAL STROMAL TUMORS | Neoplasms - metabolism | Niacinamide - analogs & derivatives | Anilides - therapeutic use | Pyrazoles - therapeutic use | Pyridines - chemistry | Humans | Anilides - chemistry | Imidazoles - chemistry | Imatinib Mesylate - therapeutic use | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Niacinamide - chemistry | Phenylurea Compounds - chemistry | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Imidazoles - therapeutic use | Pyrroles - therapeutic use | Quinazolines - chemistry | Pyridazines - therapeutic use | Pyridines - therapeutic use | Piperidines - chemistry | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Receptor Protein-Tyrosine Kinases - metabolism | Imatinib Mesylate - chemistry | Neoplasms - drug therapy | Pyridazines - chemistry | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Pyrroles - chemistry | Indoles - therapeutic use | Neoplasms - pathology | Indoles - chemistry | Tyrosine | Cell proliferation | Drugs | Medical research | Phenotypes | Clinical trials | Kinases | Proteins | Inhibitors | Modulation | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Nanoscale, ISSN 2040-3364, 03/2014, Volume 6, Issue 6, pp. 3231 - 3242
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 2/2014, Volume 31, Issue 2, pp. 394 - 400
In vitro skin permeation studies have been used extensively in the development and optimisation of delivery of actives in vivo. However, there are few reported... 
Biochemistry, general | Biomedical Engineering | Biomedicine | permeation | Pharmacy | confocal raman spectroscopy | in vitro - in vivo correlation | niacinamide | skin | Medical Law | Pharmacology/Toxicology | TOPICAL DRUG-DELIVERY | PROPYLENE-GLYCOL | APPEARANCE | SOLVENT-SOLUTE INTERACTIONS | CONFOCAL RAMAN-SPECTROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | COSOLVENT CONCENTRATION | IBUPROFEN PERMEATION | ENHANCEMENT | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Skin Absorption - physiology | Propylene Glycol - metabolism | Skin - metabolism | Solvents - chemistry | Humans | Isosorbide - metabolism | Solvents - metabolism | Administration, Cutaneous | Isosorbide - chemistry | Excipients - chemistry | Laurates - metabolism | Pharmaceutical Vehicles - chemistry | Niacinamide - chemistry | Pyrrolidinones - metabolism | Pharmaceutical Vehicles - metabolism | Female | Propylene Glycol - chemistry | Mineral Oil - metabolism | Mineral Oil - chemistry | Niacinamide - metabolism | Propylene Glycols - metabolism | Solubility | Permeability | Pyrrolidinones - chemistry | Laurates - chemistry | Propylene Glycols - chemistry | Excipients - metabolism | Isosorbide - analogs & derivatives | Drug Delivery Systems - methods | Niacinamide | Skin | Raman spectroscopy | Analysis | Drug delivery systems | Pharmacology | Transdermal medication
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 01/2017, Volume 12, Issue 1, pp. 282 - 290
Journal Article
Journal of controlled release, ISSN 0168-3659, 2017, Volume 249, pp. 111 - 122
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Journal Article
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 4, pp. 1257 - 1266
Journal Article