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Journal Article
Intensive Care Medicine, ISSN 0342-4642, 8/2011, Volume 37, Issue 8, pp. 1368 - 1377
The calcium-sensitizing drug levosimendan increases myocardial contractility and, by activating K+-channels, dilates pulmonary vessels. In the acute setting,... 
Vascular remodeling | Pediatrics | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Levosimendan | Intensive / Critical Care Medicine | Pulmonary arterial hypertension | Anesthesiology | Potassium channel | VASODILATING MECHANISMS | CELL-PROLIFERATION | CARDIAC-MUSCLE | NICORANDIL | HEART | SMOOTH-MUSCLE | INHIBITION | ARTERIAL-HYPERTENSION | ENDOTHELIAL-CELLS | CHANNELS | CRITICAL CARE MEDICINE | Myocardial Contraction - drug effects | Pyridazines - pharmacology | Hypertension, Pulmonary - chemically induced | Nicorandil - pharmacology | Glyburide - pharmacology | Hypoglycemic Agents - administration & dosage | Pyridazines - administration & dosage | Hypertension, Pulmonary - drug therapy | Glyburide - administration & dosage | Disease Models, Animal | Vasodilator Agents - pharmacology | Hydrazones - administration & dosage | Rats | Cardiotonic Agents - pharmacology | Nicorandil - administration & dosage | Potassium Channels - drug effects | Rats, Sprague-Dawley | Hydrazones - pharmacology | Hypoglycemic Agents - pharmacology | Animals | Cardiotonic Agents - administration & dosage | Pulmonary Circulation - drug effects | Airway Remodeling - drug effects | Vasodilator Agents - administration & dosage | Germany | Complications and side effects | Patient outcomes | Physiological aspects | Respiratory agents | Dosage and administration | Potassium channels | Research | Drug therapy | Pulmonary hypertension
Journal Article
Journal Article
by Wang, SJ and Duan, Y and Feng, XY and Liu, L and Shi, ZF and Wang, B and Xia, CH and Man, WR and Wang, HC and Zhao, ZJ and Sun, D
ANATOLIAN JOURNAL OF CARDIOLOGY, ISSN 2149-2263, 03/2019, Volume 21, Issue 3, pp. 163 - 171
Journal Article
Expert Opinion on Drug Safety, ISSN 1474-0338, 06/2019, Volume 18, Issue 6, pp. 537 - 547
Introduction: Nicorandil may exert cardioprotective effects in ischemic heart disease. However, its efficacy in combination with early reperfusion is... 
percutaneous coronary intervention | reperfusion injury | nicorandil | ST-elevated myocardial infarction | no-reflow phenomenon | Meta-analysis | NITRATES | MANAGEMENT | PROTECTION | ADENOSINE | PREVENTION | REPERFUSION | IMPACT | THERAPY | PCI | PHARMACOLOGY & PHARMACY
Journal Article
Lancet, The, ISSN 0140-6736, 2007, Volume 370, Issue 9597, pp. 1483 - 1493
Journal Article
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 05/2015, Volume 85, Issue 6, pp. 970 - 976
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e33367
Background: An antianginal K-ATP channel opener nicorandil has various beneficial effects on cardiovascular systems; however, its effects on pulmonary... 
SURVIVAL | ACTIVATION | INHIBITION | POTASSIUM CHANNELS | K-ATP CHANNELS | BIOLOGY | INJURY | RATS | CELL-PROLIFERATION | CARDIAC PROTECTION | Antihypertensive Agents - pharmacology | Human Umbilical Vein Endothelial Cells - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Antihypertensive Agents - administration & dosage | Hypertension, Pulmonary - physiopathology | Endothelium, Vascular - drug effects | Male | Phosphatidylinositol 3-Kinases - metabolism | NG-Nitroarginine Methyl Ester - administration & dosage | Hypertension, Pulmonary - chemically induced | Hypertension, Pulmonary - prevention & control | Enzyme Inhibitors - administration & dosage | Nicorandil - pharmacology | Glyburide - pharmacology | Glyburide - administration & dosage | Drug Therapy, Combination | Proto-Oncogene Proteins c-akt - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Human Umbilical Vein Endothelial Cells - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Injections, Intraperitoneal | Ventricular Pressure - drug effects | Rats | Familial Primary Pulmonary Hypertension | Monocrotaline - toxicity | Nicorandil - administration & dosage | Random Allocation | Rats, Sprague-Dawley | Blotting, Western | Animals | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Endothelium, Vascular - pathology | Arginine | Glibenclamide | Nitric oxide | Pulmonary hypertension | Endothelium | Heart | Systolic pressure | Bcl-2 protein | Monocrotaline | AKT protein | Kinases | Caspase-3 | Serum-free medium | Signal transduction | Rodents | Attenuation | Blood pressure | Adenosine triphosphate | Hypertension | Cell survival | Extracellular signal-regulated kinase | Caspase | Injection | Nitric-oxide synthase | Endothelial cells | 1-Phosphatidylinositol 3-kinase | NG-Nitroarginine methyl ester | Signaling | Lungs | Ventricle | Circulatory system | Mercury | Umbilical vein | Potassium | Apoptosis
Journal Article
Hypertension: Journal of the American Heart Association, ISSN 0194-911X, 11/2003, Volume 42, Issue 5, pp. 919 - 924
Journal Article