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Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 03/2012, Volume 140, Issue 1, pp. 166 - 178
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2003, Volume 87, Issue 4, pp. 969 - 980
We investigated the effect of diazoxide on neuronal survival in primary cultures of rat cortical neurons against oxygen–glucose deprivation (OGD). Diazoxide... 
mitochondrial ATP‐sensitive potassium channels | free radicals | pre‐conditioning | diazoxide | neurons | succinate dehydrogenase | Succinate dehydrogenase | Mitochondrial ATP-sensitive potassium channels | Free radicals | Diazoxide | Neurons | Pre-conditioning | SENSITIVE POTASSIUM CHANNELS | PROTEIN-KINASE-C | ARTERY-OCCLUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL CEREBRAL-ISCHEMIA | mitochondrial ATP-sensitive potassium channels | 3-NITROPROPIONIC ACID | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | FREE-RADICALS | pre-conditioning | INDUCED CARDIOPROTECTION | K-ATP CHANNEL | CARDIAC MITOCHONDRIA | Propionates - pharmacology | Cell Hypoxia - physiology | Hydroxy Acids - pharmacology | Diazoxide - pharmacology | Rats, Wistar | Neuroprotective Agents - antagonists & inhibitors | Neurons - cytology | Cerebral Cortex - cytology | Diazoxide - antagonists & inhibitors | Ischemic Preconditioning - methods | Nicorandil - pharmacology | Neuroprotective Agents - pharmacology | Glyburide - pharmacology | Time Factors | Neurons - physiology | Superoxides - metabolism | Cell Death - drug effects | Neurons - drug effects | Cell Survival - physiology | Cell Survival - drug effects | Cell Hypoxia - drug effects | Decanoic Acids - pharmacology | Succinate Dehydrogenase - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mitochondria - drug effects | Enzyme Activation - drug effects | Glucose - deficiency | Animals | Nitro Compounds | Glucose - metabolism | Oxidative Stress - drug effects | Cromakalim - pharmacology | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 3156 - 8
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2002, Volume 282, Issue 2, pp. 531 - 539
K+ channel openers have been recently recognized for their ability to protect mitochondria from anoxic injury. Yet the mechanism responsible for mitochondrial... 
Heart | Energy metabolism | Reactive oxygen species | Anoxia | Cardioprotection | Nicorandil | Diazoxide | ATP | APOPTOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | anoxia | K-ATP CHANNELS | INJURY | REPERFUSION | heart | FREE-RADICALS | nicorandil | diazoxide | reactive oxygen species | cardioprotection | PERIPHERAL VASCULAR DISEASE | RAT-HEART | GENERATION | energy metabolism | PEROXIDE | Potassium - metabolism | Hydroxy Acids - pharmacology | Diazoxide - pharmacology | Reactive Oxygen Species - metabolism | Anti-Arrhythmia Agents - pharmacology | Potassium Channels - physiology | Oxygen Consumption - physiology | Oxidative Phosphorylation - drug effects | Nicorandil - pharmacology | Adenosine Triphosphate - metabolism | Myocardium - metabolism | Myocardial Reperfusion Injury - drug therapy | Potassium Channel Blockers | Energy Metabolism - physiology | Vasodilator Agents - pharmacology | Free Radical Scavengers - metabolism | Decanoic Acids - pharmacology | Succinate Dehydrogenase - antagonists & inhibitors | Rats | Mitochondria - metabolism | Cardiotonic Agents - pharmacology | Cytochrome c Group - metabolism | Adenosine Diphosphate - pharmacology | Myocardial Reperfusion Injury - metabolism | Animals | Oxygen Consumption - drug effects | Potassium Channels - agonists | Oxidative Stress - drug effects | Energy Metabolism - drug effects | Index Medicus
Journal Article
Intensive Care Medicine, ISSN 0342-4642, 8/2011, Volume 37, Issue 8, pp. 1368 - 1377
The calcium-sensitizing drug levosimendan increases myocardial contractility and, by activating K+-channels, dilates pulmonary vessels. In the acute setting,... 
Vascular remodeling | Pediatrics | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Levosimendan | Intensive / Critical Care Medicine | Pulmonary arterial hypertension | Anesthesiology | Potassium channel | VASODILATING MECHANISMS | POTASSIUM CHANNELS | NITRIC-OXIDE SYNTHASE | K-ATP CHANNELS | HEART-FAILURE | MUSCLE-CELL PROLIFERATION | CARDIAC-MUSCLE | SMOOTH-MUSCLE | ARTERIAL-HYPERTENSION | ENDOTHELIAL-CELLS | CRITICAL CARE MEDICINE | Myocardial Contraction - drug effects | Pyridazines - pharmacology | Hypertension, Pulmonary - chemically induced | Nicorandil - pharmacology | Glyburide - pharmacology | Hypoglycemic Agents - administration & dosage | Pyridazines - administration & dosage | Hypertension, Pulmonary - drug therapy | Glyburide - administration & dosage | Disease Models, Animal | Vasodilator Agents - pharmacology | Hydrazones - administration & dosage | Rats | Cardiotonic Agents - pharmacology | Nicorandil - administration & dosage | Potassium Channels - drug effects | Rats, Sprague-Dawley | Hydrazones - pharmacology | Hypoglycemic Agents - pharmacology | Animals | Cardiotonic Agents - administration & dosage | Pulmonary Circulation - drug effects | Airway Remodeling - drug effects | Vasodilator Agents - administration & dosage | Germany | Complications and side effects | Patient outcomes | Physiological aspects | Respiratory agents | Dosage and administration | Potassium channels | Research | Drug therapy | Pulmonary hypertension | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 08/2000, Volume 102, Issue 6, pp. 706 - 712
Background-This study examines the effects of nicorandil, a K+ channel opener, on transmural dispersion of repolarization (TDR) and induction of torsade de... 
Long-QT syndrome | Nicorandil | Arrhythmia | Genes | Cells | DE-POINTES | CARDIAC & CARDIOVASCULAR SYSTEMS | genes | ABNORMALITIES | T-WAVE | long-QT syndrome | PINACIDIL | CELLULAR BASIS | cells | HERG | nicorandil | arrhythmia | PERIPHERAL VASCULAR DISEASE | POTASSIUM | VENTRICULAR ARRHYTHMIAS | BLOCKADE | HEMATOLOGY | Index Medicus | Abridged Index Medicus
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 7/2007, Volume 375, Issue 5, pp. 323 - 328
Journal Article
Cardiovascular Diabetology, ISSN 1475-2840, 11/2011, Volume 10, Issue 1, pp. 105 - 105
Background: Nicorandil, an anti-angina agent, reportedly improves outcomes even in angina patients with diabetes. However, the precise mechanism underlying the... 
Reactive oxidative species | Endothelial dysfunction | Nicorandil | Diabetes | Enos | Nadph oxidase | CARDIAC-FUNCTION | eNOS | OXYGEN SPECIES PRODUCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | DEPENDENT RELAXATION | SENSITIVE HYPERTENSIVE-RATS | NAD(P)H OXIDASE | FLOW-MEDIATED VASODILATION | NADPH oxidase | INDUCED OXIDATIVE STRESS | IN-VIVO | ENDOCRINOLOGY & METABOLISM | K-ATP CHANNEL | CORONARY-ARTERY-DISEASE | Diabetes Mellitus, Experimental - drug therapy | Reactive Oxygen Species - metabolism | Diabetes Mellitus, Experimental - enzymology | Humans | Protein Multimerization | NADPH Oxidases - metabolism | Diabetic Angiopathies - etiology | Endothelium, Vascular - drug effects | Male | Spin Labels | Endothelium, Vascular - enzymology | Femoral Artery - enzymology | Diabetic Angiopathies - physiopathology | Nicorandil - pharmacology | Time Factors | Cyclic N-Oxides - pharmacology | Acetophenones - pharmacology | Ultrasonography | Diabetic Angiopathies - enzymology | Diabetes Mellitus, Experimental - complications | Diabetic Angiopathies - prevention & control | Nitric Oxide Synthase Type III - metabolism | Diabetes Mellitus, Experimental - physiopathology | NG-Nitroarginine Methyl Ester - pharmacology | Vasodilator Agents - pharmacology | Femoral Artery - physiopathology | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Rats | Antioxidants - pharmacology | Femoral Artery - drug effects | GTP Cyclohydrolase - metabolism | Rats, Sprague-Dawley | Nitric Oxide Synthase Type III - antagonists & inhibitors | Animals | Femoral Artery - diagnostic imaging | Oxidative Stress - drug effects | Vasodilation - drug effects | Endothelial Cells - enzymology | Endothelial Cells - drug effects | Studies | Cardiovascular disease | Rodents | Veins & arteries | Index Medicus
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 06/2015, Volume 65, Issue 6, pp. 640 - 648
Journal Article