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cytokines - genetics (45) 45
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proteins (44) 44
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multidisciplinary sciences (39) 39
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activation (32) 32
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life-span (30) 30
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Kidney International, ISSN 0085-2538, 05/2018, Volume 93, Issue 5, pp. 1073 - 1085
Circulating inorganic phosphate exhibits a remarkable daily oscillation based on food intake. In humans and rodents, the daily oscillation in response to food... 
NAD | phosphate | daily oscillation | Npt2c | Nampt | Npt2a | CIRCADIAN-RHYTHM | SERUM PHOSPHATE | CARDIOVASCULAR-DISEASE | HEMODIALYSIS-PATIENTS | ADENINE-DINUCLEOTIDE | UROLOGY & NEPHROLOGY | PARATHYROID-HORMONE | DIETARY PHOSPHATE | DIURNAL-VARIATION | CHRONIC KIDNEY-DISEASE | STAGE RENAL-DISEASE | Biomarkers - urine | Liver - enzymology | Sodium-Phosphate Cotransporter Proteins, Type IIb - genetics | Kidney - enzymology | Male | Mice, 129 Strain | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Sodium-Phosphate Cotransporter Proteins, Type IIb - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Time Factors | Sodium-Phosphate Cotransporter Proteins, Type IIc - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIc - metabolism | Phosphates - urine | Phosphates - blood | Female | Cytokines - genetics | NAD - metabolism | Cytokines - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Biomarkers - blood | Nicotinamide Phosphoribosyltransferase - deficiency | Circadian Rhythm | Sodium-Phosphate Cotransporter Proteins, Type IIc - deficiency | Renal Elimination | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Sodium-Phosphate Cotransporter Proteins, Type IIb - deficiency | Sodium-Phosphate Cotransporter Proteins, Type IIa - deficiency | Cytokines - deficiency | Cytokines - antagonists & inhibitors | Intestines - enzymology | NADPH | Plasma | Renal function | Homeostasis | Proteins | Sodium phosphate | Clonal deletion | Intestine | Phosphate | Rodents | Light | Phosphoribosyltransferase | Intestinal absorption | Food | Excretion | Kidneys | Mortality | Reabsorption | Metabolism | Sodium | Hepatocytes | Food intake | Nicotinamide phosphoribosyltransferase | Nicotinamide | Kidney diseases
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 11/2009, Volume 29, Issue 21, pp. 5872 - 5888
Journal Article
Circulation Research, ISSN 0009-7330, 06/2017, Volume 120, Issue 12, pp. 1889 - 1902
RATIONALE:The thoracic aortic wall can degenerate over time with catastrophic consequences. Vascular smooth muscle cells (SMCs) can resist and repair artery... 
cell aging | DNA damage | extracellular matrix | aortic disease | ACTIVATION | HOMEOSTASIS | CARDIAC & CARDIOVASCULAR SYSTEMS | STRAND BREAK REPAIR | DNA-DAMAGE RESPONSE | ATHEROSCLEROSIS | I COLLAGEN | METABOLISM | COLONY-ENHANCING FACTOR | FIBRONECTIN | PERIPHERAL VASCULAR DISEASE | SENESCENCE | HEMATOLOGY | Tunica Media - pathology | Aortic Aneurysm, Thoracic - genetics | Nicotinamide Phosphoribosyltransferase - biosynthesis | Genome - physiology | Humans | Middle Aged | Myocytes, Smooth Muscle - pathology | Male | Laser Capture Microdissection - methods | Aortic Aneurysm, Thoracic - pathology | DNA Damage - physiology | Adult | Female | Cytokines - genetics | Aorta - enzymology | Tunica Media - physiology | Aortic Aneurysm, Thoracic - enzymology | Cells, Cultured | Myocytes, Smooth Muscle - physiology | Nicotinamide Phosphoribosyltransferase - deficiency | Mice, Knockout | Aorta - pathology | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Aged | Cytokines - deficiency | Mice | Cytokines - biosynthesis | NADPH | Senescence | Poly(ADP-ribose) | Aneurysms | Smooth muscle | Genomes | Hemorrhage | Ribose | Aorta | Phosphoribosyltransferase | Degeneration | Angiotensin II | Deoxyribonucleic acid--DNA | CpG islands | Adenine | Poly(ADP-ribose) polymerase | Thorax | NAD | Poly(ADP-ribose) Polymerase 1 | Nicotinamide phosphoribosyltransferase | Coronary vessels | Angiotensin | Nicotinamide | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e98972
Nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme for nicotinamide adenine dinucleotide (NAD(+)) synthesis, and Sirt1, an... 
DEACETYLATION | METABOLISM | POSSIBLE INVOLVEMENT | MULTIDISCIPLINARY SCIENCES | CALORIC RESTRICTION | DISEASE | AMPK | AUTOPHAGY | CELL-SURVIVAL | SIRT1 | ISCHEMIA/REPERFUSION | Heart - physiopathology | Sirtuin 1 - metabolism | Caloric Restriction | Cardiotonic Agents - metabolism | Nicotinamide Mononucleotide - metabolism | Ischemic Preconditioning | Male | Cardiotonic Agents - pharmacology | Nicotinamide Phosphoribosyltransferase - deficiency | Up-Regulation - drug effects | Animals | Reperfusion Injury - prevention & control | Nicotinamide Phosphoribosyltransferase - metabolism | Myocardial Ischemia - complications | NAD - biosynthesis | Heart - drug effects | Nicotinamide Mononucleotide - pharmacology | Mice | Myocardial Infarction - prevention & control | Reperfusion Injury - complications | Reperfusion Injury - metabolism | NADPH | Heart | Oxidative stress | Histone deacetylase | Biosynthesis | Biology | Autophagy | Medical schools | Mimicry | Proteins | Dietary restrictions | Reperfusion | Synthesis | Salvage | Ischemia | FOXO1 protein | Rodents | Aging | Phosphoribosyltransferase | Trends | Acetylation | Heart diseases | Adenosine triphosphate | Enzymes | Adenine | Cardiomyocytes | Metabolism | SIRT1 protein | Calories | NAD | Medicine | Injury prevention | Nicotinamide phosphoribosyltransferase | Nicotinamide adenine dinucleotide | Hypoxia | Nicotinamide | Preconditioning | Apoptosis
Journal Article
Cell Metabolism, ISSN 1550-4131, 08/2016, Volume 24, Issue 2, pp. 269 - 282
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2011, Volume 26, Issue 11, pp. 2656 - 2664
Human aging is associated with a progressive decline in bone mass and an accumulation of marrow fat. We found that osteoblast differentiation was reduced and... 
Nicotinamide phosphoribosyltransferase (NAMPT) | Osteoblastogenesis | Nicotinamide adenine dinucleotide (NAD) | Nicotinamide (NAM) | Mesenchymal stem cells (MSC) | SIRT1 | Adipogenesis | MESENCHYMAL STEM CELLS (MSC) | OSTEOBLAST DIFFERENTIATION | NICOTINAMIDE (NAM) | ADIPOGENESIS | BIOSYNTHESIS INHIBITOR | OSTEOBLASTOGENESIS | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | HISTONE/PROTEIN DEACETYLASES | BONE-FORMATION | NAD BIOSYNTHESIS | ENDOCRINOLOGY & METABOLISM | ADENINE-DINUCLEOTIDE | PPAR-GAMMA | ACID NICOTINAMIDE | NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) | SIR2 FAMILY | CALORIE RESTRICTION | Mesenchymal Stromal Cells - enzymology | Sirtuin 1 - metabolism | Adipogenesis - drug effects | Humans | Aging - drug effects | Adipocytes - cytology | Male | Adipocytes - drug effects | Cell Lineage - drug effects | Mesenchymal Stromal Cells - cytology | Nicotinamide Phosphoribosyltransferase - metabolism | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | NAD - metabolism | Cell Line | Mesenchymal Stromal Cells - drug effects | Intracellular Space - drug effects | Cytokines - metabolism | Niacinamide - metabolism | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Osteogenesis - drug effects | Stromal Cells - metabolism | Nicotinamide Phosphoribosyltransferase - deficiency | Sirtuin 1 - antagonists & inhibitors | Animals | Adipocytes - metabolism | Intracellular Space - metabolism | Culture Media - pharmacology | Cytokines - deficiency | Mice | Carbazoles - pharmacology | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Aging - metabolism
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2008, Volume 181, Issue 7, pp. 4685 - 4695
Journal Article
Cell Reports, ISSN 2211-1247, 09/2016, Volume 17, Issue 1, pp. 69 - 85
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 08/2016, Volume 16, Issue 7, pp. 1851 - 1860
Journal Article