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The Journal of Physiology, ISSN 0022-3751, 11/2011, Volume 589, Issue 21, pp. 5109 - 5123
Non‐Technical Summary  Cardiovascular disease and high blood pressure (hypertension) are frequent in the human population. Amiloride is commonly given as a... 
SELECTIVE INHIBITOR | PHYSIOLOGY | NERVE-TERMINALS | MEDIAL HABENULA | RAT | GANGLION NEURONS | AMILORIDE | SODIUM-CHANNEL | NEUROSCIENCES | CALCIUM-CHANNEL | SENSORY NEURONS | ISOFORM 1 | Xenopus | Nerve Tissue Proteins - deficiency | Amiloride - analogs & derivatives | Guanidines - pharmacology | Sodium Channels - physiology | Brain - physiology | Nicotine - pharmacology | Neurons - physiology | Oocytes - drug effects | Synaptic Transmission - drug effects | Neurons - drug effects | Nicotinic Agonists - pharmacology | Sodium Channels - deficiency | Sodium-Hydrogen Exchangers - antagonists & inhibitors | Pyrazoles - pharmacology | Cell Line | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Tissue Proteins - physiology | Acid Sensing Ion Channels | Sodium-Hydrogen Exchangers - physiology | Mice, Inbred C57BL | Sodium Channel Blockers - pharmacology | Nerve Tissue Proteins - genetics | Mice, Knockout | Brain - drug effects | Animals | Oocytes - physiology | Receptors, Nicotinic - physiology | Amiloride - pharmacology | Mice | Sodium Channels - genetics | In Vitro Techniques | Hypertension | Cardiovascular disease | Potassium | Investigations | Drugs | Brain | Brain slice preparation | Nervous system | Antagonists | Oocytes | Potassium channels (calcium-gated) | Antagonism | Amiloride | Synaptic transmission | Habenula | Cardiorespiratory | Medications | Blood pressure | Communication | Peripheral nervous system | Sodium channels | gamma -Aminobutyric acid receptors | Cross-reactivity | Excitability | Acidity | Acetylcholine receptors (nicotinic) | Glutamatergic transmission | Blood diseases | Cardiovascular diseases | Animal subjects | Index Medicus | Neuroscience
Journal Article
Journal Article
Pharmacology Biochemistry and Behavior, ISSN 0091-3057, 2014, Volume 125, pp. 40 - 47
An aspect of nicotine reinforcement that may contribute to tobacco addiction is the effect of nicotine to enhance the motivational properties of... 
Dopamine | Serotonin | Reinforcement | Conditioned reinforcement | Nicotine
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 10/2000, Volume 295, Issue 1, pp. 321 - 327
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167071 - e0167071
Background Cigarette smoking plays an important role in the progression of chronic kidney disease (CKD). Nicotine, one of the major components of cigarette... 
ACETYLCHOLINE-RECEPTORS | CIGARETTE-SMOKING | NMDA RECEPTORS | RISK-FACTOR | MULTIDISCIPLINARY SCIENCES | RENAL-FUNCTION | INJURY | DIABETIC-NEPHROPATHY | CHRONIC KIDNEY-DISEASE | CARDIOVASCULAR MORBIDITY | ROS PRODUCTION | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Apoptosis - genetics | Male | Nicotinic Antagonists - pharmacology | Spin Labels | Reactive Oxygen Species - agonists | Nicotine - pharmacology | MAP Kinase Kinase 4 - metabolism | Cyclic N-Oxides - pharmacology | Mitogen-Activated Protein Kinase 1 - genetics | Female | MAP Kinase Kinase 4 - antagonists & inhibitors | Membrane Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Receptors, Nicotinic - metabolism | Podocytes - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Membrane Proteins - genetics | Tissue Culture Techniques | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | Nicotine - antagonists & inhibitors | Podocytes - cytology | Reactive Oxygen Species - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Podocytes - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | MAP Kinase Kinase 4 - genetics | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Oxidative Stress - drug effects | Receptors, Nicotinic - genetics | Cell Line, Transformed | Mitogen-Activated Protein Kinase 1 - metabolism | Oxidative stress | Physiological aspects | Research | Health aspects | Health/Alcohol and other Drugs/Information/Nicotine and Tobacco | Nicotine | Smoking | Apoptosis | Cell proliferation | Reactive oxygen species | Phosphorylation | Laboratories | Syngeneic grafts | Downstream effects | Tempol | Acetylcysteine | Superoxide dismutase | Antagonists | mRNA | Medical schools | Antioxidants | Proteins | Receptors | Rodents | Mesangial cells | Localization | Medical research | Extracellular signal-regulated kinase | JNK protein | Superoxide | Permeability | Gene expression | Cigarette smoking | Signaling | Molecular modelling | Inhibitors | Acetylcholine receptors (nicotinic) | In vivo methods and tests | Acetylcholine | Kidney diseases | Diabetes | Kidney transplantation | Index Medicus
Journal Article
EUROPEAN NEUROPSYCHOPHARMACOLOGY, ISSN 0924-977X, 06/2014, Volume 24, Issue 6, pp. 964 - 973
Many physiological systems in mammals are linked to the body's master circadian rhythm in the sleep/wake cycle and dysfunctions in this rhythm has been... 
Circadian rhythms | Suprachiasmatic nucleus | CHOLINERGIC ANTAGONIST | PSYCHIATRY | EVOKED DOPAMINE RELEASE | SCHIZOPHRENIA | NEUROSCIENCES | CLINICAL NEUROLOGY | CARBACHOL | Major depression | GANGLION-CELLS | NICOTINIC ACETYLCHOLINE-RECEPTOR | PHARMACOLOGY & PHARMACY | PROJECTIONS | BINDING | Nicotine | COGNITIVE DEFICITS
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2007, Volume 554, Issue 2, pp. 164 - 174
Stimulatory actions of nicotine on mesocorticolimbic dopamine transmission are partly mediated by nicotine-induced glutamate release acting on ionotropic and... 
Self-administration | LY341495 | Withdrawal | Dependence | MPEP | Intracranial self-stimulation | Reward | Metabotropic glutamate receptor | Nicotine | reward | nicotine | CONDITIONED REWARD | DECREASED NICOTINE | metabotropic glutamate receptor | LOCOMOTOR-ACTIVITY | COCAINE | METABOTROPIC GLUTAMATE RECEPTORS | withdrawal | intracranial self-stimulation | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | DOPAMINE NEURONS | self-administration | IN-VIVO | dependence | PHARMACOLOGY & PHARMACY | BRAIN | Ganglionic Stimulants - administration & dosage | Nicotine - administration & dosage | Rats, Wistar | Receptors, Metabotropic Glutamate - physiology | Male | Amino Acids - pharmacology | Eating - physiology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Self Administration | Drug Interactions | Time Factors | Receptor, Metabotropic Glutamate 5 | Xanthenes - pharmacology | Pyridines - administration & dosage | Injections, Intraperitoneal | Excitatory Amino Acid Antagonists - administration & dosage | Rats | Excitatory Amino Acid Antagonists - pharmacology | Eating - drug effects | Reinforcement Schedule | Animals | Pyridines - pharmacology | Ganglionic Stimulants - pharmacology | Infusions, Intravenous | Substance Withdrawal Syndrome - physiopathology | Substance Withdrawal Syndrome - psychology | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Index Medicus
Journal Article