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Journal Article
2010, Advances in experimental medicine and biology, ISBN 1441964444, Volume 683., xix, 118
This book investigates insect nicotinic acetylcholine receptors. It explores the involvement of insect nicotinic receptors in learning and memory processes,... 
toxicity | Insects | Receptors, Nicotinic | Insecticides | Physiology | Nicotinic receptors | Physiological effect | Synaptic Transmission | Biomedicine general | Biomedicine
Book
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64828
textabstractThe brain needs mechanisms able to correlate plastic changes with local circuit activity and internal functional states. At the cerebellum input... 
HIPPOCAMPAL SYNAPTIC PLASTICITY | TACTILE STIMULATION | RAT CEREBELLUM | ACH RECEPTORS | NMDA RECEPTORS | NEUROTRANSMITTER RELEASE | MULTIDISCIPLINARY SCIENCES | GRANULE CELL SYNAPSES | DIFFERENTIALLY FACILITATE | SPATIAL-ORGANIZATION | DENTATE GYRUS | Reflex, Vestibulo-Ocular - physiology | Synaptic Transmission - physiology | Synapses - physiology | Rats | Nerve Fibers - drug effects | Cerebellum - physiology | Animals | Nerve Fibers - physiology | Long-Term Potentiation - drug effects | Receptors, Nicotinic - physiology | Reflex, Vestibulo-Ocular - drug effects | alpha7 Nicotinic Acetylcholine Receptor - physiology | Long-Term Potentiation - physiology | Synaptic Transmission - drug effects | Mice | Nicotinic Agonists - pharmacology | Brain | Cerebellum | Potentiation | Neurosciences | Calcium | Synaptic strength | Memory | Activation | Neuromodulation | Fibers | Learning | Receptors | Plasticity | Physiology | Dendrites | Trends | Gating | Adaptation | Channel gating | Granule cells | Long-term potentiation | Pharmacology | Plasticity (cerebellar) | Neurology | Granular materials | Sensory stimulation | Acetylcholine receptors (nicotinic) | Plastic properties | Mossy fibers | Nicotine | Receptors, Nicotinic | Neurons and Cognition | Synaptic Transmission | Life Sciences | Nicotinic Agonists | Long-Term Potentiation | Nerve Fibers | Synapses | Reflex, Vestibulo-Ocular | alpha7 Nicotinic Acetylcholine Receptor | Acetylcholine
Journal Article
Biochemistry, ISSN 0006-2960, 06/2014, Volume 53, Issue 23, pp. 3758 - 3766
We isolated a novel, atypical long-chain three-finger toxin (TFT), α-elapitoxin-Dpp2d (α-EPTX-Dpp2d), from black mamba (Dendroaspis polylepis polylepis) venom.... 
KAPPA-BUNGAROTOXIN | ALPHA-NEUROTOXINS | SNAKE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | NICOTINIC RECEPTOR PROBE | CRYSTAL-STRUCTURES | 3-FINGERED TOXINS | PROTEINS | BINDING | ACETYLCHOLINE-RECEPTOR | Reptilian Proteins - chemistry | Humans | alpha7 Nicotinic Acetylcholine Receptor - antagonists & inhibitors | Nicotinic Antagonists - pharmacology | Nicotinic Agonists - chemistry | Reptilian Proteins - pharmacology | Receptors, Nicotinic - chemistry | Neurons - metabolism | Amino Acid Sequence | Nicotinic Antagonists - isolation & purification | Receptors, Nicotinic - metabolism | Nerve Tissue Proteins - agonists | Carrier Proteins - antagonists & inhibitors | Recombinant Proteins - chemistry | alpha7 Nicotinic Acetylcholine Receptor - genetics | Reptilian Proteins - isolation & purification | Elapid Venoms - pharmacology | Nicotinic Antagonists - chemistry | Calcium Signaling - drug effects | Neurotoxins - metabolism | Protein Conformation | Protein Processing, Post-Translational | alpha7 Nicotinic Acetylcholine Receptor - metabolism | Reptilian Proteins - metabolism | Elapid Venoms - chemistry | Nicotinic Antagonists - metabolism | Molecular Sequence Data | Neurotoxins - isolation & purification | Carrier Proteins - chemistry | Protein Stability | Elapid Venoms - isolation & purification | Neurons - drug effects | Nicotinic Agonists - pharmacology | Binding, Competitive | Recombinant Proteins - metabolism | Cell Line | Nerve Tissue Proteins - antagonists & inhibitors | Neurotoxins - chemistry | alpha7 Nicotinic Acetylcholine Receptor - agonists | Recombinant Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Neurotoxins - pharmacology | Carrier Proteins - genetics | Sequence Alignment | Animals | Carrier Proteins - metabolism | Elapidae - metabolism | Elapid Venoms - metabolism | Receptors, Nicotinic - genetics | Venom | Chemical properties | Research
Journal Article
Neurotoxicology, ISSN 0161-813X, 07/2013, Volume 37, pp. 127 - 133
Clothianidin is a neonicotinoid insecticide developed in the early 2000s. We have recently demonstrated that it was a full agonist of α-bungarotoxin-sensitive... 
Cockroach | Neonicotinoid | Calcium | DUM neurons | Nicotinic receptors | cAMP | Insect | Clothianidin | CAMP | ENTRY | INVOLVEMENT | NEUROSCIENCES | UNPAIRED MEDIAN NEURONS | NEONICOTINOID INSECTICIDES | MEMORY | TARGETS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | INSECT NEUROSECRETORY-CELLS | AGONIST | Neonicotinoids | Guanidines - pharmacology | Male | Nicotinic Antagonists - pharmacology | Dose-Response Relationship, Drug | Time Factors | Neurons - metabolism | Neurons - drug effects | Cyclic AMP - metabolism | Insect Proteins - metabolism | Nicotinic Agonists - pharmacology | Insecticides - pharmacology | Cell Line | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Second Messenger Systems - drug effects | alpha7 Nicotinic Acetylcholine Receptor - agonists | Periplaneta | Animals | Membrane Potentials | Calcium Signaling - drug effects | Thiazoles - pharmacology | alpha7 Nicotinic Acetylcholine Receptor - metabolism | Insect Proteins - drug effects | Bungarotoxins - pharmacology | Index Medicus | Insecticides | Life Sciences | Nicotinic Agonists | Thiazoles | Genetics | Second Messenger Systems | Calcium Signaling | Environmental Sciences | Receptors, Nicotinic | Neurons | Biochemistry, Molecular Biology | Cyclic AMP | Guanidines | Nicotinic Antagonists | Bungarotoxins | Insect Proteins | alpha7 Nicotinic Acetylcholine Receptor
Journal Article
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 3/2012, Volume 220, Issue 1, pp. 1 - 14
Nicotine is the main addictive component of tobacco and modifies brain function via its action on neuronal acetylcholine nicotinic receptors (nAChRs). The... 
Nucleus accumbens | Neurosciences | Knockout mice | Biomedicine | Dopamine | Reinforcement | Pharmacology/Toxicology | Nicotinic receptors | Psychiatry | Ventral tegmental area | Nicotine | PSYCHIATRY | PLACE PREFERENCE | RELEASE | NEUROSCIENCES | ADDICTION | RAT NUCLEUS-ACCUMBENS | ACETYLCHOLINE-RECEPTORS | STIMULATION REWARD | SELF-STIMULATION | PHARMACOLOGY & PHARMACY | BRAIN | SUBUNIT | Nicotine - administration & dosage | Receptors, Nicotinic - metabolism | Mice, Inbred C57BL | Nucleus Accumbens - metabolism | Reinforcement (Psychology) | Male | Mice, Knockout | Nicotine - pharmacology | Nicotinic Agonists - administration & dosage | Self Administration | Animals | Microdialysis | Time Factors | Mice, Mutant Strains | Ventral Tegmental Area - metabolism | Mice | Neurons - metabolism | Reward | Receptors, Nicotinic - genetics | Dopamine - metabolism | Nicotinic Agonists - pharmacology | alpha7 Nicotinic Acetylcholine Receptor | Phenols | Acetylcholine | Genetically modified organisms | Drug addiction | Psychopharmacology | Rodents | Ventral tegmentum | Brain | Circuits | Mesolimbic system | Neurons | Drug self-administration | Tobacco | Addiction | Extracellular levels | Acetylcholine receptors (nicotinic) | Nucleus Accumbens | Receptors, Nicotinic | Neurons and Cognition | Psychology and behavior | Neurobiology | Life Sciences | Nicotinic Agonists | Ventral Tegmental Area | Cognitive Sciences
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 05/2018, Volume 151, pp. 214 - 225
Journal Article
Toxins, ISSN 2072-6651, 09/2016, Volume 8, Issue 9, pp. 249 - 67
The cyclic imine toxin 20-methyl spirolide G (20-meSPX-G), produced by the toxigenic dinoflagellate Alexandrium ostenfeldii/Alexandrium peruvianum, has been... 
Xenopus oocytes | Dinoflagellate toxin | Spirolides | Nicotinic currents | Nicotinic acetylcholine receptors | Competition-binding assays | Neuromuscular transmission | Molecular docking | PHYCOTOXINS | SUBTYPES | competition-binding assays | HIGH-AFFINITY | nicotinic currents | dinoflagellate toxin | WATERS | STRUCTURAL DETERMINANTS | ALEXANDRIUM-OSTENFELDII DINOPHYCEAE | spirolides | GYMNODIMINE | PINNATOXINS E | molecular docking | neuromuscular transmission | DIVERSITY | SHELLFISH | TOXICOLOGY | nicotinic acetylcholine receptors | Electric Stimulation | Isometric Contraction - drug effects | Neuromuscular Junction - drug effects | Neuromuscular Junction - metabolism | Nicotinic Antagonists - metabolism | Humans | Torpedo | Muscle, Skeletal - innervation | Muscle, Skeletal - metabolism | Structure-Activity Relationship | Action Potentials | Cholinergic Fibers - metabolism | Dose-Response Relationship, Drug | Transfection | Receptors, Nicotinic - chemistry | Muscle, Skeletal - drug effects | HEK293 Cells | Female | Binding Sites | Bridged Bicyclo Compounds, Heterocyclic - metabolism | Cholinergic Fibers - drug effects | Nicotinic Antagonists - toxicity | Spiro Compounds - chemistry | Binding, Competitive | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Xenopus laevis | Animals | Pyridines - metabolism | Spiro Compounds - toxicity | Nicotinic Antagonists - chemistry | Chickens | Protein Binding | Protein Conformation | Mice | Molecular Docking Simulation | In Vitro Techniques | Receptors, Nicotinic - genetics | Spiro Compounds - metabolism | Xenopus | Cricetulus | Neurons and Cognition | Neurobiology | Oocytes | Spiro Compounds | Life Sciences | Neuromuscular Junction | Isometric Contraction | Muscle Cells | CHO Cells | Cricetinae | Receptors, Nicotinic | Psychology and behavior | Marine Toxins | Patch-Clamp Techniques | Receptors, Muscarinic | Neurotoxicity Syndromes | Cognitive Sciences | alpha7 Nicotinic Acetylcholine Receptor
Journal Article
Biochemistry, ISSN 0006-2960, 11/2013, Volume 52, Issue 47, pp. 8480 - 8488
The differential action of the novel agonist JN403 at neuronal α7 and muscle nicotinic receptors (AChRs) was explored by using a combination of functional and... 
Nicotinic Agonists - metabolism | Nicotinic Antagonists - metabolism | Humans | Molecular Conformation | Torpedo | Fetal Proteins - metabolism | Nicotinic Antagonists - pharmacology | Fetal Proteins - agonists | Protein Subunits - metabolism | Carbamates - metabolism | Nerve Tissue Proteins - chemistry | Receptors, Nicotinic - chemistry | Muscle Proteins - metabolism | Nicotinic Agonists - pharmacology | Carbamates - pharmacology | Protein Subunits - genetics | Membrane Potentials - drug effects | Recombinant Proteins - metabolism | Cell Line | Receptors, Nicotinic - metabolism | alpha7 Nicotinic Acetylcholine Receptor - chemistry | Nerve Tissue Proteins - agonists | Protein Subunits - agonists | Quinuclidines - pharmacology | Recombinant Proteins - chemistry | alpha7 Nicotinic Acetylcholine Receptor - genetics | alpha7 Nicotinic Acetylcholine Receptor - agonists | Nerve Tissue Proteins - genetics | Muscle Proteins - genetics | Nerve Tissue Proteins - metabolism | Muscle Proteins - agonists | Animals | Nicotinic Antagonists - chemistry | Calcium Signaling - drug effects | Protein Binding | Fetal Proteins - genetics | Mice | Molecular Docking Simulation | Muscle Proteins - chemistry | Protein Subunits - chemistry | alpha7 Nicotinic Acetylcholine Receptor - metabolism | Kinetics | Quinuclidines - metabolism | Receptors, Nicotinic - genetics | Fetal Proteins - chemistry
Journal Article