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1. Full Text Nicotine replacement therapy for smoking cessation
by Stead, Lindsay F and Stead, Lindsay F and Perera, Rafael and Perera, Rafael and Bullen, Chris and Bullen, Chris and Mant, David and Mant, David and Hartmann-Boyce, Jamie and Hartmann-Boyce, Jamie and Cahill, Kate and Cahill, Kate and Lancaster, Tim and Lancaster, Tim
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2012, Volume 11, Issue 12, p. CD000146
Background The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and... 
PATCH THERAPY | CONTAINING CHEWING GUM | Tablets | NASAL SPRAY | CLINICAL-TRIAL | Smoking [prevention & control]; Smoking Cessation [methods] | Humans | Administration, Inhalation | Administration, Cutaneous | RANDOMIZED CONTROLLED-TRIAL | Chewing Gum | MEDICINE, GENERAL & INTERNAL | Nicotine [administration & dosage]; Nicotinic Agonists [administration & dosage]; Randomized Controlled Trials as Topic | WITHDRAWAL SYMPTOMS | DOUBLE-BLIND TRIAL | PLACEBO-CONTROLLED TRIAL | TRANSDERMAL NICOTINE | AMERICAN LIGHT SMOKERS | Nicotinic Agonists - administration & dosage | Nicotine - administration & dosage | Tobacco Use Cessation Devices | Smoking Cessation - methods | Smoking Prevention | Randomized Controlled Trials as Topic
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2. Full Text The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control
by Higgins, GA and Silenieks, LB and Rossmann, A and Rizos, Z and Noble, K and Soko, AD and Fletcher, PJ
NEUROPSYCHOPHARMACOLOGY, ISSN 0893-133X, 04/2012, Volume 37, Issue 5, pp. 1177 - 1191
Lorcaserin ((1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine HCl) is a selective 5-HT2C receptor agonist with clinical efficacy in phase-III obesity... 
reward | SMOKING-CESSATION | ACTIVATION | nicotine dependence | STIMULATION | PSYCHIATRY | SATIETY SEQUENCE | addiction | LOCOMOTOR-ACTIVITY | COCAINE | 5-HT2C receptor | NEUROSCIENCES | REACTION-TIME-TASK | SEROTONERGIC DRUGS | PHARMACOLOGY | impulsivity | PHARMACOLOGY & PHARMACY | D-FENFLURAMINE | obesity | Nicotine - administration & dosage | Motor Activity - drug effects | Male | Serotonin Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Self Administration | Conditioning, Operant - drug effects | Reaction Time - drug effects | Discrimination (Psychology) - drug effects | Behavior, Animal - drug effects | Indoles - pharmacology | Drug Administration Routes | Choice Behavior - drug effects | Reinforcement (Psychology) | Rats | Benzazepines - pharmacology | Rats, Sprague-Dawley | Feeding Behavior - drug effects | Eating - drug effects | Nicotinic Agonists - administration & dosage | Rotarod Performance Test | Animals | Analysis of Variance | Aminopyridines - pharmacology | Impulsive Behavior - drug therapy | metabolic disorders | animal models | nicotine | relapse | eating | serotonin | Original | addiction and substance abuse
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3. Full Text Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial
by Anthenelli, Robert M, Prof and Benowitz, Neal L, Prof and West, Robert, Prof and St Aubin, Lisa, DVM and McRae, Thomas, MD and Lawrence, David, PhD and Ascher, John, MD and Russ, Cristina, MD and Krishen, Alok, MS and Evins, A Eden, Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10037, pp. 2507 - 2520
Summary Background Substantial concerns have been raised about the neuropsychiatric safety of the smoking cessation medications varenicline and bupropion.... 
Internal Medicine | SMOKING-CESSATION | DEPRESSION | MEDICINE, GENERAL & INTERNAL | ABSTINENCE | RISK | SCHIZOPHRENIA | SUICIDE | ADVERSE EVENTS | Varenicline - adverse effects | Dopamine Uptake Inhibitors - adverse effects | Double-Blind Method | Humans | Middle Aged | Male | Mental Disorders - complications | Treatment Outcome | Smoking Cessation - methods | Smoking Prevention | Bupropion - administration & dosage | Varenicline - administration & dosage | Dopamine Uptake Inhibitors - administration & dosage | Nicotinic Agonists - adverse effects | Young Adult | Nicotinic Agonists - administration & dosage | Tobacco Use Cessation Products | Adolescent | Adult | Female | Aged | Smoking - psychology | Bupropion - adverse effects | Smoking Cessation - psychology | Drugs | Clinical trials | Smoking cessation programs | Smokers | Mental illness | Smoking cessation | Side effects | Mental disorders | Health risk assessment | Transdermal medication | Nicotine | Smoking
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4. Full Text Electronic cigarettes for smoking cessation and reduction
by Mcrobbie, Hayden and McRobbie, Hayden and Bullen, Chris and Bullen, Chris and Hartmann-Boyce, Jamie and Hartmann-Boyce, Jamie and Hajek, Peter and Hajek, Peter
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 12, Issue 12, p. CD010216
Background Electronic cigarettes (ECs) are electronic devices that heat a liquid -usually comprising propylene glycol and glycerol, with or without nicotine... 
DEVICE E-CIGARETTE | CONTROLLED-TRIAL | SAFETY | Humans | Nicotine [administration & dosage] | QUIT SMOKING | Middle | Randomized Controlled Trials as Topic | MEDICINE, GENERAL & INTERNAL | IMPACT | TOBACCO PRODUCT USE | NICOTINE-DELIVERY | Tobacco Use Cessation Products | HARM | Nicotinic Agonists [administration & dosage] | SMOKERS | Publication Bias | Aged | Smoking [epidemiology; prevention & control] | WITHDRAWAL | Electronic Cigarettes [adverse effects; instrumentation] | Cohort Studies | Smoking Cessation [methods] | Nicotine - administration & dosage | Tobacco Use Cessation Devices | Middle Aged | Electronic Nicotine Delivery Systems - adverse effects | Smoking Cessation - methods | Smoking Prevention | Electronic Nicotine Delivery Systems - instrumentation | Nicotinic Agonists - administration & dosage | Smoking - epidemiology
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5. Full Text Electronic cigarettes for smoking cessation
by Hartmann-Boyce, Jamie and Mcrobbie, Hayden and Bullen, Chris and Begh, Rachna and Stead, Lindsay F and Hajek, Peter
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 09/2016, Volume 2016, Issue 9, p. CD010216
Background Electronic cigarettes (ECs) are electronic devices that heat a liquid into an aerosol for inhalation. The liquid usually comprises propylene glycol... 
DEVICE E-CIGARETTE | Humans | Middle Aged | Nicotine [administration & dosage] | RANDOMIZED CONTROLLED-TRIAL | QUIT SMOKING | Randomized Controlled Trials as Topic | DELIVERY | MEDICINE, GENERAL & INTERNAL | TOBACCO PRODUCT USE | Tobacco Use Cessation Products | Nicotinic Agonists [administration & dosage] | SMOKERS | HARM PERCEPTIONS | Publication Bias | NICOTINE REPLACEMENT THERAPY | VAPOR PRODUCT | HELP PATIENTS | Smoking [epidemiology; prevention & control] | Electronic Cigarettes [adverse effects; instrumentation] | Cohort Studies | Smoking Cessation [methods]
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6. Full Text Phase 2 trial of an alpha-7 nicotinic receptor agonist (TC-5619) in negative and cognitive symptoms of schizophrenia
by Walling, David and Marder, Stephen R and Kane, John and Fleischhacker, W. Wolfgang and Keefe, Richard S. E and Hosford, David A and Dvergsten, Chris and Segreti, Anthony C and Beaver, Jessica S and Toler, Steven M and Jett, John E and Dunbar, Geoffrey C
Schizophrenia Bulletin, ISSN 0586-7614, 2016, Volume 42, Issue 2, pp. 335 - 343
Objectives: This trial was conducted to test the effects of an alpha7 nicotinic receptor full agonist, TC-5619, on negative and cognitive symptoms in subjects... 
Schizophrenia | Negative symptoms | Cognition | TARGETS | schizophrenia | cognition | DEFICITS | PSYCHIATRY | negative symptoms | Severity of Illness Index | Outcome Assessment (Health Care) | Humans | Middle Aged | Quinuclidines - pharmacology | Benzofurans - administration & dosage | Benzofurans - pharmacology | Male | alpha7 Nicotinic Acetylcholine Receptor - agonists | Quinuclidines - administration & dosage | Young Adult | Nicotinic Agonists - administration & dosage | Schizophrenia - physiopathology | Adult | Female | Schizophrenia - drug therapy | Nicotinic Agonists - pharmacology | Regular
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7. Full Text Nicotine replacement therapy for smoking cessation
by Stead, L.F and Perera, R and Bullen, C and Mant, D and Lancaster, T
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2008, Issue 1, p. CD000146
Background The aim of nicotine replacement therapy (NRT) is temporarily to replace much of the nicotine from cigarettes to reduce motivation to smoke and... 
Chewing gum | Randomized controlled trials as topic | Administration, inhalation | Nicotine [administration & dosage] | Smoking [ prevention & control] | Administration, cutaneous | Nicotinic agonists [administration & dosage] | cutaneous | PATCH THERAPY | CONTAINING CHEWING GUM | NASAL SPRAY | CLINICAL-TRIAL | administration | FOLLOW-UP | smoking [prevention & control] | RANDOMIZED CONTROLLED-TRIAL | randomized controlled trials | smoking cessation [methods] | nicotine [administration & dosage] | nicotinic agonists [administration & dosage] | inhalation | MEDICINE, GENERAL & INTERNAL | DOUBLE-BLIND TRIAL | chewing gum | PLACEBO-CONTROLLED TRIAL | TRANSDERMAL NICOTINE | tablets | humans | AMERICAN LIGHT SMOKERS | Chewing Gum | Nicotinic Agonists - administration & dosage | Nicotine - administration & dosage | Tablets | Humans | Administration, Inhalation | Administration, Cutaneous | Smoking Cessation - methods | Smoking Prevention | Randomized Controlled Trials as Topic
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