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Life Sciences, ISSN 0024-3205, 11/2017, Volume 188, pp. 1 - 9
The vasorelaxant effects of the anti-diabetic drug, mitiglinide in phenylephrine (Phe)-pre-contracted aortic rings were examined. Arterial tone measurement was... 
Mitiglinide | Voltage-dependent K+ channel | Aortic smooth muscle | SERCA pump | channel | Voltage-dependent K | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | PHYSIOLOGICAL ROLES | ATPASE | ARTERIES | GENES | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | AGENTS | TYPE-2 DIABETES-MELLITUS | EXPRESSION | MODULATION | Potassium Channels, Voltage-Gated - agonists | Endothelium, Vascular - drug effects | Male | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Muscle, Smooth - drug effects | Drug Interactions | Phenylephrine - pharmacology | Glyburide - pharmacology | Oxadiazoles - pharmacology | Aorta, Thoracic - physiology | Indoles - pharmacology | Muscle, Smooth - physiology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - antagonists & inhibitors | Aorta, Thoracic - drug effects | Isoindoles - pharmacology | 4-Aminopyridine - pharmacology | Rabbits | Nifedipine - pharmacology | Adenine - analogs & derivatives | Vasodilator Agents - pharmacology | Vasodilator Agents - antagonists & inhibitors | Adenine - pharmacology | Barium - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - physiology | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Thapsigargin - pharmacology | Carbazoles - pharmacology | Isoindoles - antagonists & inhibitors | Protein kinase A | Electric potential | Protein kinase G | Smooth muscle | Activation | Potassium conductance | Guanylate cyclase | Channels | Vasodilation | Ca2+-transporting ATPase | Adenylate cyclase | Thapsigargin | Phenylephrine | Measurement methods | Aorta | Life sciences | Potassium channels (voltage-gated) | Inhibition | Pretreatment | Glibenclamide | Diabetes mellitus | Muscles | Cyclopiazonic acid | Endothelium | Nifedipine | Resistance | Signaling | Conductance | Endoplasmic reticulum | Adenosine triphosphatase | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 12, pp. 3992 - 4003
The NMDAR plays a unique and vital role in subcellular signaling. Calcium influx initiates signaling cascades important for both synaptic plasticity and... 
IN-VITRO | STATE TRANSITIONS | LONG-TERM POTENTIATION | SUBUNIT COMPOSITION | D-ASPARTATE RECEPTOR | HUNTINGTONS-DISEASE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | DIFFERENTIAL ROLES | CELL-DEATH | NUCLEUS-ACCUMBENS | Microfluidic Analytical Techniques - methods | Electric Stimulation | Rats, Wistar | Embryo, Mammalian | Coculture Techniques | Receptors, N-Methyl-D-Aspartate - metabolism | Neurons - cytology | Cerebral Cortex - cytology | Corpus Striatum - cytology | N-Methylaspartate - pharmacology | CREB-Binding Protein - metabolism | Glycine Agents - pharmacology | Transfection - methods | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Tetrodotoxin - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | GABA-A Receptor Antagonists - pharmacology | Nifedipine - pharmacology | Synapses - physiology | Vesicular Glutamate Transport Protein 1 - metabolism | Cells, Cultured | Rats | Sodium Channel Blockers - pharmacology | Strychnine - pharmacology | Bicuculline - pharmacology | Calcium Channel Blockers - pharmacology | Nerve Tissue Proteins - metabolism | Pregnancy | Patch-Clamp Techniques | Animals | Analysis of Variance | Glutamate Decarboxylase - metabolism | Luminescent Proteins - genetics | Signal Transduction - physiology | Luminescent Proteins - metabolism
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2009, Volume 62, Issue 1, pp. 53 - 71
The molecular mechanisms controlling the termination of cortical interneuron migration are unknown. Here, we demonstrate that, prior to synaptogenesis,... 
CELLBIO | DEVBIO | MOLNEURO | NEURONAL MIGRATION | CHLORIDE HOMEOSTASIS | DOWN-REGULATION | GABAERGIC INTERNEURONS | GENE-EXPRESSION | CL-COTRANSPORTER KCC2 | TANGENTIAL MIGRATION | DEVELOPING CEREBRAL-CORTEX | NEUROSCIENCES | MEDIAL GANGLIONIC EMINENCE | INTERMEDIATE ZONE | Interneurons - physiology | Muscimol - pharmacology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Sequence Deletion | Age Factors | Calcium - metabolism | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Green Fluorescent Proteins - genetics | Cerebral Cortex - cytology | Cell Movement - physiology | Quinoxalines - pharmacology | omega-Conotoxin GVIA - pharmacology | Symporters - antagonists & inhibitors | Female | Organ Culture Techniques | Bicuculline - analogs & derivatives | Animals, Newborn | Membrane Potentials - drug effects | Nifedipine - pharmacology | Glutamic Acid - pharmacology | RNA, Small Interfering - pharmacology | Valine - analogs & derivatives | gamma-Aminobutyric Acid - pharmacology | Calcium Channels, L-Type - physiology | Mice, Transgenic | Bicuculline - pharmacology | Calcium Channel Blockers - pharmacology | Electroporation - methods | Membrane Potentials - physiology | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Symporters - metabolism | Gene Expression Regulation - drug effects | Pregnancy | Cell Movement - drug effects | GABA Agents - pharmacology | Animals | Models, Biological | Symporters - genetics | LIM-Homeodomain Proteins | Mice | Mice, Inbred BALB C | Transcription Factors | Valine - pharmacology | GABA | Methyl aspartate | Calcium channels | Neurosciences | Glutamate | Membrane potentials | Brain | Motility | Microscopy | Neurons | Rodents | Migration | Colleges & universities | Index Medicus
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 355 - 365
Binding of specific microbial epitopes [MAMPs (microbe-associated molecular patterns)] to PRRs (pattern recognition receptors) and subsequent receptor kinase... 
Ionotropic glutamate receptor channel | Elicitor | Microbe-associated molecular pattern | Calcium channel | Calcium signature | Plant immunity | calcium channel | calcium signature | DEFENSE | GATED ION-CHANNEL | microbe-associated molecular pattern | SIGNATURES | elicitor | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+ CHANNELS | PLANT-CELLS | ionotropic glutamate receptor channel | PLASMA-MEMBRANE | ROOT HAIRS | PERCEPTION | GENES | PATTERN-RECOGNITION RECEPTORS | plant immunity | Calcium Channels - metabolism | Seedlings - genetics | Type C Phospholipases - metabolism | Type C Phospholipases - antagonists & inhibitors | Arabidopsis Proteins - metabolism | Diltiazem - pharmacology | Estrenes - pharmacology | Plants, Genetically Modified | Pyrrolidinones - pharmacology | Gene Expression Regulation, Plant | Neomycin - pharmacology | Transcription, Genetic | Kynurenic Acid - pharmacology | Dideoxyadenosine - pharmacology | Arabidopsis Proteins - genetics | Nifedipine - pharmacology | Arabidopsis - drug effects | Receptors, Ionotropic Glutamate - metabolism | Aequorin - chemistry | Seedlings - drug effects | Calcium Channel Blockers - pharmacology | Chitin - pharmacology | Verapamil - pharmacology | Arabidopsis - metabolism | Arabidopsis - genetics | Receptors, Pattern Recognition | Bacterial Proteins - pharmacology | Calcium Signaling - drug effects | Alloxan - pharmacology | Mitogen-Activated Protein Kinases - genetics | Enzyme Activation | Arabidopsis Proteins - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Seedlings - metabolism
Journal Article
Circulation, ISSN 0009-7322, 09/2006, Volume 114, Issue 13, pp. 1372 - 1379
Background - At birth, the increase in oxygen causes contraction of the ductus arteriosus, thus diverting blood flow to the lungs. Although this contraction is... 
Oxygen | Ion channels | Vasoconstriction | Ductus arteriosus, patent | Heart defects, congenital | heart defects | CARDIAC & CARDIOVASCULAR SYSTEMS | ductus arteriosus, patent | TRPC1 | RECEPTOR | CLOSURE | congenital | CAPACITATIVE CA2+ ENTRY | PULMONARY VASOCONSTRICTION | CYTOSOLIC CALCIUM | ion channels | CONSTRICTION | PERIPHERAL VASCULAR DISEASE | vasoconstriction | SMOOTH-MUSCLE-CELLS | RABBIT | oxygen | Oxygen - pharmacology | Tetraethylammonium - pharmacology | Calcium Signaling - physiology | Maleimides - pharmacology | Potassium Channels - physiology | Thiourea - pharmacology | Polyunsaturated Alkamides | Isoquinolines - pharmacology | rho-Associated Kinases | Niflumic Acid - pharmacology | Indoles - pharmacology | Endocannabinoids | Ductus Arteriosus - physiology | Boron Compounds - pharmacology | Mibefradil - pharmacology | Nifedipine - pharmacology | Calcium - pharmacology | Oxidation-Reduction | Protein-Serine-Threonine Kinases - physiology | Rabbits - embryology | Calcium Channels, L-Type - physiology | Imidazoles - pharmacology | Calcium Channel Blockers - pharmacology | Potassium Channels - drug effects | Sulfonamides - pharmacology | Arachidonic Acids - pharmacology | Ductus Arteriosus - embryology | Patch-Clamp Techniques | Animals | Menthol - pharmacology | Ruthenium Red - pharmacology | Muscle Contraction - drug effects | Calcium Channels, L-Type - drug effects | Muscle Contraction - physiology | Thapsigargin - pharmacology | Cytosol - metabolism | In Vitro Techniques | Intracellular Signaling Peptides and Proteins - physiology | Thiourea - analogs & derivatives
Journal Article
Steroids, ISSN 0039-128X, 03/2011, Volume 76, Issue 4, pp. 409 - 415
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2011, Volume 37, Issue 3, pp. 353 - 357
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2009, Volume 329, Issue 3, pp. 928 - 937
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2007, Volume 104, Issue 24, pp. 9982 - 9987
Arginine contains the guanidinium group and thus has structural similarity to ligands of imidazoline and α-2 adrenoceptors (α-2 AR). Therefore, we investigated... 
Cell culture techniques | Signal transduction | Receptors | Imidazolines | Fluorescence | Agonists | Ligands | Toxins | Endothelial cells | Whooping cough | Calcium | Agmatine | Rauwolscine | rauwolscine | calcium | DEPENDENT VASODILATION | VASCULAR RELAXATION | MULTIDISCIPLINARY SCIENCES | agmatine | RELAXING FACTOR | PORCINE CORONARY-ARTERIES | RELEASE | SYNTHASE | SMOOTH-MUSCLE | CHOLESTEROL-FED RABBITS | S-NITROSOTHIOLS | Endothelium, Vascular - cytology | Aniline Compounds | Humans | Receptors, Adrenergic, alpha-2 - metabolism | Culture Media, Serum-Free | Adrenergic alpha-Antagonists - pharmacology | Calcium - analysis | Agmatine - pharmacology | Virulence Factors, Bordetella - pharmacology | Type C Phospholipases - antagonists & inhibitors | Yohimbine - pharmacology | Dose-Response Relationship, Drug | Idazoxan - pharmacology | Arginine - antagonists & inhibitors | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Agmatine - chemistry | Dexmedetomidine - pharmacology | Molecular Structure | Cell Culture Techniques | Nitric Oxide Synthase Type III - metabolism | Umbilical Veins - cytology | Nitrates - analysis | NG-Nitroarginine Methyl Ester - pharmacology | Nitric Oxide - biosynthesis | Nifedipine - pharmacology | Idazoxan - chemistry | Endothelial Cells - metabolism | Nitric Oxide - antagonists & inhibitors | Cells, Cultured | Imidazolines - pharmacology | Calcium Channel Blockers - pharmacology | Enzyme Activation - drug effects | Arginine - chemistry | Xanthenes | Endothelial Cells - cytology | Arginine - pharmacology | Lipopolysaccharides - pharmacology | Second Messenger Systems - physiology | Nitrites - analysis | Endothelial Cells - enzymology | Fluorescent Dyes | Amino acids | Biochemistry | Chemical synthesis | Nitric oxide | Cells | Veins & arteries | Biological Sciences
Journal Article