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Pharmacology Biochemistry and Behavior, ISSN 0091-3057, 06/2001, Volume 69, Issue 1-2, pp. 59 - 70
Current evidence indicates that the acute locomotor stimulant effects of caffeine involve dopamine (DA) receptor activation; however, few studies have... 
nisoxetine
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2000, Volume 39, Issue 4, pp. 578 - 585
Intracerebroventricular injections of the irreversible dopamine transporter (DAT) inhibitor, RTI-76 {3 beta -(3-p-chlorophenyl) tropan-2 beta -carboxylic acid... 
nisoxetine
Journal Article
Neurochemistry international, ISSN 0197-0186, 9/2016, Volume 98, pp. 122 - 128
Modulation of neurotransmission by the catecholamine dopamine (DA) is conserved across phylogeny. In the nematode C. elegans , excess DA signaling triggers... 
C. elegans | nematode | dopamine | nisoxetine | transporter
Journal Article
Synapse, ISSN 0887-4476, 03/1999, Volume 31, Issue 4, pp. 250 - 255
In the present study, [ super(3)H]nisoxetine binding to norepinephrine (NE) uptake sites and [ super(3)H]norepinephrine uptake were investigated within... 
nisoxetine
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 04/2018, Volume 59, Issue 4, pp. 659 - 664
Degeneration of noradrenergic neurons may underlie the disabling nonmotor symptoms in patients with Parkinson disease (PD). Quantification of the loss of... 
C-11-MeNER | HUMAN BRAIN | noradrenaline transporter | Parkinson disease | UPTAKE SITES | H-3 NISOXETINE | HUMAN LOCUS-COERULEUS | NOREPINEPHRINE TRANSPORTERS | IN-VIVO | NONMOTOR SYMPTOMS | positron emission tomography | RAPHE NUCLEI | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
NEUROSCIENCE LETTERS, ISSN 0304-3940, 04/2013, Volume 541, pp. 184 - 189
alpha(2)-Adrenergic agonists simulate norepinephrine (NE) action on alpha(2) receptors of sympathetic neurons to mediate feedback inhibition of NE release.... 
CLONIDINE | alpha 2 adrenergic agonist | Dexmedetomide | METAIODOBENZYLGUANIDINE | Nisoxetine | ALPHA-ADRENERGIC AGONISTS | Norepinephrine transporter | MONOAMINE TRANSPORTERS | NEUROBLASTOMA | NORADRENALINE | NEUROSCIENCES | KETAMINE
Journal Article
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 10/2014, Volume 25, Issue 18-19, pp. 1264 - 1269
Biotransformation of 3-chloro-1-phenylpropan-1-one in sixteen selected cultures of yeast strains has been carried out. For most of the biocatalysts studied the... 
NISOXETINE | ASYMMETRIC TRANSFER HYDROGENATION | ENANTIOMERS | RESOLUTION | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | TOMOXETINE | FLUOXETINE | CHEMISTRY, INORGANIC & NUCLEAR | KETONES | CHEMOENZYMATIC SYNTHESIS | DERIVATIVES | SEROTONIN UPTAKE | Enantiomers
Journal Article
Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 2005, Volume 29, Issue 2, pp. 297 - 303
Journal Article
Journal of Molecular Catalysis. B, Enzymatic, ISSN 1381-1177, 12/2013, Volume 97, pp. 150 - 155
Nitrile hydrolysing enzymes have found wide use in the pharmaceutical industry for the production of fine chemicals. This work presents a strategy that... 
High throughput screening | Nitrile hydrolysing activity | Enantioselectivity | Biotransformation | Bacterial isolates | NISOXETINE | BIOTRANSFORMATIONS | AMIDE | ENANTIOMERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, PHYSICAL | FLUOXETINE | BIOCATALYSIS | ASYMMETRIC HYDROLYSIS | CATALYZED HYDROLYSIS | DERIVATIVES
Journal Article
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, ISSN 1461-1457, 04/2014, Volume 17, Issue 4, pp. 553 - 560
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2002, Volume 22, Issue 2, pp. 389 - 395
Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the prefrontal cortex. This suggests that dopamine in this region is... 
Nucleus accumbens | Caudate | GBR 12909 | Nisoxetine | Cocaine | Frontal cortex | Synaptosomes | INCREASES EXTRACELLULAR DOPAMINE | MONOAMINE TRANSMITTERS | cocaine | synaptosomes | SUBCELLULAR-LOCALIZATION | nucleus accumbens | caudate | RAT PREFRONTAL CORTEX | NEUROSCIENCES | MICE LACKING | NUCLEUS-ACCUMBENS | frontal cortex | nisoxetine | NORADRENALINE CARRIER | SEROTONIN | STRIATUM | Norepinephrine - antagonists & inhibitors | Synaptosomes - drug effects | Nucleus Accumbens - chemistry | Frontal Lobe - metabolism | Nucleus Accumbens - metabolism | Synaptosomes - metabolism | Brain - metabolism | Dose-Response Relationship, Drug | Membrane Transport Proteins - deficiency | Membrane Transport Proteins - genetics | Fluoxetine - analogs & derivatives | Membrane Transport Proteins - metabolism | Membrane Glycoproteins | Dopamine - metabolism | Dopamine Plasma Membrane Transport Proteins | Fluoxetine - pharmacology | Caudate Nucleus - chemistry | Dopamine Uptake Inhibitors - pharmacology | Symporters - deficiency | Dopamine - pharmacokinetics | Nerve Tissue Proteins | Frontal Lobe - chemistry | Synaptosomes - chemistry | Piperazines - pharmacology | Symporters - metabolism | Caudate Nucleus - metabolism | Mice, Knockout | Cocaine - pharmacology | Norepinephrine Plasma Membrane Transport Proteins | Animals | Symporters - genetics | Brain Chemistry | Mice
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2005, Volume 94, Issue 2, pp. 337 - 351
We have synthesized and evaluated several new ligands for imaging the norepinephrine transporter (NET) system in baboons with positron emission tomography... 
lortalamine | oxaprotiline | norepinephrine transporter | positron emission tomography | nisoxetine | reboxetine | Reboxetine | Norepinephrine transporter | Lortalamine | Positron emission tomography | Oxaprotiline | Nisoxetine | RAT-BRAIN MEMBRANES | BIOCHEMISTRY & MOLECULAR BIOLOGY | THREO-METHYLPHENIDATE | UPTAKE SITES | NEUROSCIENCES | BABOON BRAIN | H-3 NISOXETINE | LABELED NOREPINEPHRINE | SEROTONIN | BINDING-SITES | IN-VIVO EVALUATION | PET | Brain - diagnostic imaging | Chromatography, High Pressure Liquid - methods | Fluoxetine - pharmacokinetics | Maprotiline - blood | Magnetic Resonance Imaging - methods | Positron-Emission Tomography | Morpholines - blood | Maprotiline - analogs & derivatives | Brain - metabolism | Dose-Response Relationship, Drug | Tissue Distribution | Drug Interactions | Fluorine Radioisotopes - pharmacokinetics | Time Factors | Nordefrin - antagonists & inhibitors | Fluoxetine - analogs & derivatives | Protein Binding - drug effects | Radioligand Assay - methods | Adrenergic Uptake Inhibitors - blood | Adrenergic Uptake Inhibitors - pharmacokinetics | Carbon Radioisotopes - pharmacokinetics | Autoradiography - methods | Image Processing, Computer-Assisted - methods | Fluoxetine - blood | Symporters - metabolism | Binding, Competitive - drug effects | Maprotiline - pharmacokinetics | Papio | Norepinephrine Plasma Membrane Transport Proteins | Benzopyrans - blood | Animals | Benzopyrans - pharmacokinetics | Brain Mapping | Brain Chemistry | Mice | Morpholines - pharmacokinetics | Evaluation Studies as Topic | Tomography | Comparative analysis | Monkeys & apes | Positrons | Emissions
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 2005, Volume 143, Issue 1, pp. 87 - 94
Binding assays for the norepinephrine (NE) transporter (NET) with [ H]nisoxetine have generally yielded weak potencies for compounds related to cocaine and... 
[ 3H]CIT | CFT | Benztropine | GBR 12909 | Desipramine | [ 3H]Nisoxetine | Mazindol | Norepinephrine transporter | Norepinephrine | Cocaine | Methylphenidate | CIT | H]Nisoxetine | H]CIT | norepinephrine | BIOGENIC-AMINE TRANSPORTERS | methylphenidate | [H-3]Nisoxetine | RAT-BRAIN MEMBRANES | SYNAPTOSOMAL PREPARATIONS | cocaine | HUMAN DOPAMINE TRANSPORTER | BIOCHEMICAL RESEARCH METHODS | HIGH-AFFINITY | MONOAMINE TRANSPORTERS | [H-3]CIT | UPTAKE SITES | NEUROSCIENCES | desipramine | mazindol | COCAINE BINDING | H-3 NISOXETINE | norepinephrine transporter | IDENTICAL CONDITIONS | benztropine | Brain Chemistry - drug effects | Cocaine - metabolism | Temperature | Fluoxetine - pharmacokinetics | Humans | Piperazines - metabolism | Dopamine Uptake Inhibitors - pharmacokinetics | Dopamine Uptake Inhibitors - metabolism | Fluoxetine - analogs & derivatives | Binding Sites - physiology | Radioligand Assay - methods | Cell Membrane - metabolism | Piperazines - pharmacokinetics | Buffers | Binding Sites - drug effects | Cell Membrane - drug effects | Cell Line | Reproducibility of Results | Binding, Competitive - physiology | Cocaine - pharmacokinetics | Symporters - metabolism | Brain Chemistry - physiology | Binding, Competitive - drug effects | Norepinephrine Plasma Membrane Transport Proteins | Norepinephrine - metabolism | Fluoxetine - metabolism | Symporters - drug effects | Cell research | Chemical properties | Coordination compounds | Heterocyclic compounds | Noradrenaline
Journal Article
PSYCHOPHARMACOLOGY, ISSN 0033-3158, 09/2006, Volume 188, Issue 1, pp. 119 - 127
Rationale Atomoxetine is a potent and selective norepinephrine transporter (NET) reuptake inhibitor acting as a nonstimulant for the treatment of... 
RADIOLIGAND | PSYCHIATRY | norepinephrine transporter occupancy | RADIOTRACERS | atomoxetine | NEUROSCIENCES | nonhuman primate brain | H-3 NISOXETINE | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | POSITRON-EMISSION-TOMOGRAPHY | PHARMACOLOGY & PHARMACY | MICE | RAT-BRAIN | BINDING-SITES | AUTORADIOGRAPHY | PET | (S,S)-[F-18]FMeNER-D-2 | REBOXETINE ANALOGS
Journal Article
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