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Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2010, Volume 12, Issue 8, pp. 648 - 658
Type 2 diabetes (T2DM) is a complex disease combining defects in insulin secretion and insulin action. New compounds have been developed for improving... 
DPP-4 inhibitor | Alogliptin | Sitagliptin | Linagliptin | Vildagliptin | Type 2 diabetes mellitus | Pharmacokinetics | Saxagliptin | DIPEPTIDYL PEPTIDASE-4 INHIBITOR | linagliptin | RECEPTOR AGONISTS | saxagliptin | SINGLE-DOSE PHARMACOKINETICS | RENAL IMPAIRMENT | ORAL ANTIDIABETIC AGENTS | sitagliptin | vildagliptin | HEALTHY MALE-VOLUNTEERS | alogliptin | IV INHIBITOR | ENDOCRINOLOGY & METABOLISM | pharmacokinetics | type 2 diabetes mellitus | HEPATIC IMPAIRMENT | TYPE-2 DIABETES-MELLITUS | Dipeptides - pharmacokinetics | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Half-Life | Male | Pyrazines - therapeutic use | Nitriles - pharmacokinetics | Pyrrolidines - therapeutic use | Drug Interactions | Adamantane - therapeutic use | Female | Triazoles - pharmacokinetics | Sitagliptin Phosphate | Adamantane - pharmacokinetics | Adamantane - analogs & derivatives | Triazoles - therapeutic use | Hypoglycemic Agents - therapeutic use | Hypoglycemic Agents - pharmacokinetics | Dipeptides - therapeutic use | Pyrrolidines - pharmacokinetics | Randomized Controlled Trials as Topic | Dipeptidyl-Peptidase IV Inhibitors - pharmacokinetics | Pyrazines - pharmacokinetics | Diabetes Mellitus, Type 2 - drug therapy | Nitriles - therapeutic use | Type 2 diabetes | Physiological aspects | Glucose | Metabolites | Dextrose | Cytochrome P-450
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 03/2012, Volume 72, Issue 6, pp. 1494 - 1503
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 06/2018, Volume 70, Issue 6, pp. 723 - 731
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 10/2016, Volume 55, Issue 10, pp. 1191 - 1204
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 3/2012, Volume 51, Issue 3, pp. 147 - 162
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 2, pp. 153 - 157
Glucagon-like peptide-1 (GLP-1) receptor agonists (liraglutide, exenatide, lixisenatide) have recently been used as anti-diabetes drugs. We examined... 
pharmacokinetics | dipeptidyl peptidase-4 inhibitor | glucagon-like peptide-1 receptor agonist | target molecular binding occupancy | pharmacodynamics | Dipeptidyl peptidase-4 inhibitor | Pharmacodynamics | Pharmacokinetics | Glucagon-like peptide-1 receptor agonist | Target molecular binding occupancy | GLUCAGON-LIKE PEPTIDE-1 | PHARMACOLOGY & PHARMACY | PROMOTES SATIETY | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - metabolism | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Peptides - pharmacokinetics | Nitriles - pharmacokinetics | Peptides - administration & dosage | Peptides - metabolism | Hypoglycemic Agents - administration & dosage | Pyrrolidines - metabolism | Adamantane - therapeutic use | Adamantane - administration & dosage | Adamantane - analogs & derivatives | Hypoglycemic Agents - therapeutic use | Sitagliptin Phosphate - administration & dosage | Hyperglycemia - prevention & control | Hypoglycemic Agents - pharmacokinetics | Piperidines - administration & dosage | Piperidines - metabolism | Pyrrolidines - pharmacokinetics | Adamantane - metabolism | Models, Molecular | Uracil - therapeutic use | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Dipeptidyl-Peptidase IV Inhibitors - pharmacokinetics | Liraglutide - therapeutic use | Venoms - therapeutic use | Ligands | Venoms - metabolism | Sitagliptin Phosphate - pharmacokinetics | Venoms - pharmacokinetics | Nitriles - therapeutic use | Liraglutide - metabolism | Sitagliptin Phosphate - metabolism | Pyrrolidines - administration & dosage | Diabetes Mellitus, Type 2 - metabolism | Molecular Targeted Therapy | Pyrrolidines - therapeutic use | Dose-Response Relationship, Drug | Nitriles - administration & dosage | Glucagon-Like Peptide-1 Receptor - metabolism | Liraglutide - pharmacokinetics | Uracil - administration & dosage | Venoms - administration & dosage | Dipeptidyl-Peptidase IV Inhibitors - metabolism | Piperidines - pharmacokinetics | Adamantane - pharmacokinetics | Nitriles - metabolism | Reproducibility of Results | Diabetes Mellitus, Type 2 - blood | Algorithms | Piperidines - therapeutic use | Sitagliptin Phosphate - therapeutic use | Uracil - metabolism | Liraglutide - administration & dosage | Diabetes Mellitus, Type 2 - drug therapy | Drug Monitoring | Uracil - pharmacokinetics | Glucagon-Like Peptide-1 Receptor - agonists | Peptides - therapeutic use | Uracil - analogs & derivatives | Binding | Drugs | Effectiveness | Peptidase | Glucagon | Diabetes mellitus | Theoretical analysis | Low level | Receptors | Inhibitors | Nitric oxide | Occupancy | Hemoglobin | Agonists | Glucagon-like peptide 1 | Drug dosages
Journal Article
Journal Article
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 09/2019, Volume 174, pp. 63 - 69
A rapid, sensitive and reliable bioanalytical method was firstly developed and validated based on ultra-performance liquid chromatography tandem mass... 
Human plasma | Metabolite | E0703 | Radioprotective | UPLC–MS/MS | Pharmacokinetic | CHEMISTRY, ANALYTICAL | MASS-SPECTROMETRY ASSAY | ESTRADIOL | ESTROGEN | UPLC-MS/MS | PHARMACOLOGY & PHARMACY | RADIATION | Metabolites | Ionization | Formic acid | Nitriles | Liquid chromatography | Mass spectrometry | Organic acids
Journal Article