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Biochemical journal, ISSN 0264-6021, 2000, Volume 351, Issue 1, pp. 95 - 105
Journal Article
Nature neuroscience, ISSN 1546-1726, 2004, Volume 7, Issue 7, pp. 711 - 718
Voltage-dependent Kv2.1 K+ channels, which mediate delayed rectifier Kv currents (I-K), are expressed in large clusters on the somata and dendrites of... 
ALPHA-SUBUNITS | RAT HIPPOCAMPAL-NEURONS | MAMMALIAN BRAIN | ACTIVATION | GATED POTASSIUM CHANNELS | RECEPTOR | NEOCORTICAL PYRAMIDAL NEURONS | IDENTIFICATION | KV2.1 K+ CHANNEL | BINDING | NEUROSCIENCES | Potassium - metabolism | Okadaic Acid - pharmacology | Potassium Channels, Voltage-Gated | Pyramidal Cells - metabolism | Cyclosporine - pharmacology | Cell Count | Neuronal Plasticity - drug effects | Pyrethrins - pharmacology | Translocation, Genetic - drug effects | Patch-Clamp Techniques - methods | Seizures - chemically induced | Dose-Response Relationship, Drug | Potassium Channels - metabolism | Phosphoprotein Phosphatases - pharmacology | Seizures - physiopathology | Drug Interactions | Neuronal Plasticity - physiology | Time Factors | Dendrites - physiology | Potassium Chloride - pharmacology | Nitriles | Pyramidal Cells - drug effects | Phosphorylation - drug effects | Cadmium Chloride - pharmacology | Ionophores - pharmacology | Potassium Channel Blockers - pharmacology | Disease Models, Animal | Animals, Newborn | Membrane Potentials - drug effects | Dendrites - drug effects | Translocation, Genetic - physiology | Glutamic Acid - pharmacology | Kainic Acid - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Nitrendipine - pharmacology | Calcium Channel Blockers - pharmacology | Delayed Rectifier Potassium Channels | Hippocampus - cytology | Membrane Potentials - physiology | Shab Potassium Channels | Calcimycin - pharmacology | Blotting, Western | Animals | Ion Channel Gating - drug effects | Physiological aspects | Phosphorylation | Ion channels | Research | Neurons
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2013, Volume 57, Issue 2, pp. 751 - 757
Journal Article
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 10/2007, Volume 85, Issue 7, pp. 558 - 566
It has been recognized that protease‐activated receptors (PARs), interleukin (IL)‐4 and IL‐6 are involved in the pathogenesis of allergic diseases, and that... 
mast cell | IL‐4 | IL‐12 | trypsin | protease‐activated receptor | tryptase | IL-4 | Trypsin | Mast cell | Protease-activated receptor | IL-12 | Tryptase | SERINE PROTEINASES | THROMBIN RECEPTORS | HISTAMINE-RELEASE | INDUCTION | IMMUNOLOGY | HUMAN AIRWAYS | CELL BIOLOGY | SMOOTH-MUSCLE | INTERFERON-GAMMA | IN-VIVO | protease-activated receptor | VASCULAR ENDOTHELIAL-CELLS | INFLAMMATORY MEDIATORS | Receptors, Proteinase-Activated - metabolism | Nitriles - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Receptors, Proteinase-Activated - genetics | Trypsin - pharmacology | Mast Cells - metabolism | Flavonoids - pharmacology | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-12 - pharmacology | Butadienes - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Imidazoles - pharmacology | Tyrphostins - pharmacology | Mast Cells - drug effects | Gene Expression Regulation - drug effects | Interleukin-4 - secretion | Animals | Tryptases - pharmacology | Mice | Pyridines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Tyrphostins, pharmacology | Up-Regulation | Chromones, pharmacology | Trypsin, pharmacology | Humans | Imidazoles, pharmacology | Tryptases, pharmacology | Oligopeptides, pharmacology | Interleukin-12, pharmacology | Flow Cytometry | Pyridines, pharmacology | Polymerase Chain Reaction | Receptor, PAR-1, drug effects | Morpholines, pharmacology | RNA, Messenger, metabolism | Flavonoids, pharmacology | Receptor, PAR-2, drug effects | Receptors, Thrombin, drug effects | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Butadienes, pharmacology | Down-Regulation | Mast Cells, drug effects | Interleukin-6, secretion | Nitriles, pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4, secretion | Fluorescent Antibody Technique
Journal Article
by Zhou, S and Liu, L and Li, H and Eilers, G and Kuang, Y and Shi, S and Yan, Z and Li, X and Corson, J M and Meng, F and Zhou, H and Sheng, Q and Fletcher, J A and Ou, W-B
British journal of cancer, ISSN 1532-1827, 2014, Volume 110, Issue 10, pp. 2479 - 2488
Background: Mesothelioma is a notoriously chemotherapy-resistant neoplasm, as is evident in the dismal overall survival for patients with those of... 
ACTIVATION | GROWTH-FACTOR-RECEPTOR | FACTOR SCATTER FACTOR | MALIGNANT PLEURAL MESOTHELIOMA | PHASE-II | tyrosine kinases | ANTITUMOR-ACTIVITY | MET RECEPTOR | PI3K/AKT/MDM2 | PI3K/AKT/mTOR | INHIBITION | ONCOLOGY | C-MET | mesothelioma | Mesothelioma - pathology | Nitriles - pharmacology | Humans | Neoplasm Proteins - physiology | Receptor Protein-Tyrosine Kinases - physiology | Neoplasm Proteins - antagonists & inhibitors | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Quinolines - pharmacology | MAP Kinase Signaling System | TOR Serine-Threonine Kinases - antagonists & inhibitors | raf Kinases - physiology | RNA Interference | TOR Serine-Threonine Kinases - physiology | Antineoplastic Agents - pharmacology | Chromones - pharmacology | Everolimus | Butadienes - pharmacology | Sirolimus - analogs & derivatives | RNA, Small Interfering - pharmacology | Morpholines - pharmacology | Imidazoles - pharmacology | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Sirolimus - pharmacology | Indazoles - pharmacology | Signal Transduction - drug effects | Mesothelioma - enzymology | Cell Line, Tumor | Phosphatidylinositol 3-Kinases - physiology | Protein Kinase Inhibitors - pharmacology | Cell Cycle - drug effects | Drug Screening Assays, Antitumor | Translational Therapeutics | PI3K | mTOR | MDM2 | AKT
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 2018, Volume 128, pp. 324 - 339
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 12/2005, Volume 315, Issue 3, pp. 1346 - 1353
Journal Article
Cancer Letters, ISSN 0304-3835, 2012, Volume 320, Issue 1, pp. 104 - 110
Abstract Molecularly targeted therapies have emerged as the leading theme in cancer therapeutics. Multi-cytotoxic drug regimens have been highly successful,... 
Hematology, Oncology and Palliative Medicine | Combination index | Dasatinib | Molecular targeted therapy | Rapamycin | ACTIVATION | SRC | BCR-ABL | TUMOR | MECHANISMS | SIMULATION | CHEMOTHERAPY | ONCOLOGY | RESISTANCE | SYSTEMS | KINASES | Niacinamide - analogs & derivatives | Paclitaxel - pharmacology | Nitriles - pharmacology | Humans | Epothilones - pharmacology | Thiazoles - administration & dosage | Chromones - administration & dosage | Phenylurea Compounds | Benzenesulfonates - administration & dosage | Tamoxifen - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Nitriles - administration & dosage | Benzenesulfonates - pharmacology | Female | Chromones - pharmacology | Paclitaxel - administration & dosage | Butadienes - pharmacology | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Morpholines - administration & dosage | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Pyrimidines - pharmacology | Breast Neoplasms - drug therapy | Sirolimus - pharmacology | Drug Synergism | Sirolimus - administration & dosage | Signal Transduction - drug effects | Butadienes - administration & dosage | Epothilones - administration & dosage | Tamoxifen - pharmacology | Cell Line, Tumor | Pyridines - pharmacology | Thiazoles - pharmacology | Care and treatment | Oncology, Experimental | Genes | Breast cancer | Research | Tamoxifen | Cancer | Index Medicus
Journal Article
Nature chemical biology, ISSN 1552-4469, 2014, Volume 10, Issue 8, pp. 656 - 663
Journal Article