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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2017, Volume 27, Issue 11, pp. 2459 - 2464
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2017, Volume 174, Issue 14, pp. 2161 - 2173
Azoreductases are flavoenzymes that have been characterized in a range of prokaryotes and eukaryotes. Bacterial azoreductases are associated with the... 
NITROAROMATIC COMPOUNDS | NAD(P)H-QUINONE OXIDOREDUCTASE-1 | FMN-DEPENDENT AZOREDUCTASE | DT-DIAPHORASE | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | OXIDOREDUCTASE 1 NQO1 | 5-AMINOSALICYLIC ACID | BETA-LAPACHONE | Neoplasms - metabolism | Bacteria - metabolism | Quinones - chemistry | Humans | Bacteria - drug effects | Anti-Bacterial Agents - metabolism | Antineoplastic Agents - chemistry | Nitrofurans - pharmacology | Neoplasms - drug therapy | Antineoplastic Agents - metabolism | Azo Compounds - chemistry | Anti-Bacterial Agents - chemistry | Nitrofurans - metabolism | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Azo Compounds - metabolism | NADH, NADPH Oxidoreductases - metabolism | Azo Compounds - pharmacology | Quinones - pharmacology | Nitrofurans - chemistry | Quinones - metabolism | Oxidases | Drugs | Drug resistance in microorganisms | Chemotherapy | Gastrointestinal diseases | Quinone | Physiological aspects | Azo compounds | Single nucleotide polymorphisms | Chromosomes | Cancer | Inflammatory bowel diseases | Prokaryotes | Medical treatment | Single-nucleotide polymorphism | Metabolism | Drug development | Substrates | NAD | Quinones | Reduction | Eukaryotes | Antibiotics | Intestine | Medical prognosis | Antibiotic resistance | Azoreductase | Azo | Drug metabolism | Bacteria | Colon | Themed Section | Review
Journal Article
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3842 - 3852
The tumor-suppressor p53 prevents cancer development via initiating cell-cycle arrest, cell death, repair, or antiangiogenesis processes. Over 50% of human... 
UBIQUITINATION | CELLS | CHEMOSENSITIVITY | IN-VITRO | INHIBITION | RESCUE | ONCOLOGY | STABILIZATION | MDM2 | MUTATIONS | BINDING | Tumor Suppressor Protein p53 - antagonists & inhibitors | Tumor Suppressor Proteins - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Piperazines - toxicity | Piperazines - chemistry | Nitrofurans - pharmacology | Recombinant Fusion Proteins - metabolism | Antineoplastic Agents - toxicity | Gene Knockdown Techniques | Genes, p53 | Proteolysis | Tumor Suppressor Proteins - genetics | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Camptothecin - analogs & derivatives | Nitrofurans - chemistry | Tumor Stem Cell Assay | DNA-Binding Proteins - physiology | DNA-Binding Proteins - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Tumor Suppressor Protein p53 - metabolism | Antineoplastic Agents - chemistry | DNA-Binding Proteins - genetics | Piperazines - pharmacology | Drug Synergism | Xenograft Model Antitumor Assays | Tumor Suppressor Proteins - physiology | Tumor Protein p73 | Signal Transduction - drug effects | Nitrofurans - toxicity | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Nuclear Proteins - physiology | Colorectal Neoplasms - pathology | Camptothecin - pharmacology | Drug Screening Assays, Antitumor
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2006, Volume 149, Issue 5, pp. 551 - 559
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 01/2007, Volume 165, Issue 1, pp. 1 - 13
Journal Article