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Science, ISSN 0036-8075, 11/2008, Volume 322, Issue 5906, pp. 1392 - 1395
Journal Article
Journal Article
Haematologica, ISSN 0390-6078, 07/2015, Volume 100, Issue 7, pp. 927 - 934
We previously demonstrated vast expansion of hypoxic areas in the leukemic microenvironment and provided a rationale for using hypoxia-activated prodrugs.... 
STEM-CELLS | INHIBITION | PR-104A | ACUTE MYELOGENOUS LEUKEMIA | BONE-MARROW | I TRIAL | KETO REDUCTASE 1C3 | HIF-1-ALPHA | HEMATOLOGY | CANCER-THERAPY | CHEMOTHERAPY | Recurrence | Humans | Middle Aged | Male | Antineoplastic Agents, Alkylating - administration & dosage | Carbonic Anhydrases - metabolism | Thrombocytopenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Anemia - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Bone Marrow - metabolism | Enterocolitis - genetics | Antigens, Neoplasm - metabolism | Bone Marrow - drug effects | Biomarkers - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications | Gene Expression | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Leukemia, Myeloid, Acute - pathology | Anemia - chemically induced | Hypoxia - complications | Thrombocytopenia - chemically induced | Thrombocytopenia - pathology | Nitrogen Mustard Compounds - adverse effects | Remission Induction | Hypoxia - pathology | Antineoplastic Agents, Alkylating - adverse effects | Enterocolitis - pathology | Prodrugs - administration & dosage | Hypoxia - drug therapy | Neutropenia - metabolism | Nitrogen Mustard Compounds - administration & dosage | Carbonic Anhydrases - genetics | Anemia - pathology | Leukemia, Myeloid, Acute - complications | Prodrugs - metabolism | Leukemia, Myeloid, Acute - drug therapy | Neutropenia - pathology | Adult | Female | Neutropenia - chemically induced | Neutropenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Carbonic Anhydrase IX | Enterocolitis - chemically induced | Antigens, Neoplasm - genetics | Nitroimidazoles - pharmacology | Thrombocytopenia - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Anemia - metabolism | Prodrugs - adverse effects | Hypoxia - genetics | Nitrogen Mustard Compounds - metabolism | Bone Marrow - pathology | Aged | Enterocolitis - metabolism | Antineoplastic Agents, Alkylating - metabolism | Leukemia, Myeloid, Acute - genetics
Journal Article
The Journal of antimicrobial chemotherapy, ISSN 0305-7453, 02/2018, Volume 73, Issue 2, pp. 265 - 279
Metronidazole, a nitroimidazole, remains a front-line choice for treatment of infections related to inflammatory disorders of the gastrointestinal tract... 
ANTIMICROBIAL SUSCEPTIBILITY | CLOSTRIDIUM-DIFFICILE INFECTION | NITROIMIDAZOLE DRUGS | INFECTIOUS DISEASES | MULTIDRUG-RESISTANT | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | BACTEROIDES-FRAGILIS GROUP | TRICHOMONAS-VAGINALIS | LACTATE-DEHYDROGENASE ACTIVITY | PHARMACOLOGY & PHARMACY | IN-VITRO ACTIVITY
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 06/2008, Volume 7, Issue 6, pp. 2357 - 2367
The first proteomic analysis of Trypanosoma cruzi resistance to Benznidazole (BZ) is presented. The differential proteome of T. cruzi with selected in vivo... 
Resistance | Proteome | Benznidazole | 2-DE | Trypanosoma cruzi | POPULATION | INCREASED EXPRESSION | BIOCHEMICAL RESEARCH METHODS | CHAGAS-DISEASE | EPIMASTIGOTES | resistance | proteome | OLD YELLOW ENZYME | GLUTAMATE-DEHYDROGENASE | PEROXIDASE | INFECTION | PROTEINS | CONTAINING SUPEROXIDE-DISMUTASE | Glutamate Dehydrogenase - analysis | Peroxiredoxins - metabolism | Nucleoside-Diphosphate Kinase - metabolism | Electrophoresis, Gel, Two-Dimensional | Nucleoside-Diphosphate Kinase - analysis | Hydroxyprostaglandin Dehydrogenases - metabolism | Cysteine Endopeptidases - analysis | Tandem Mass Spectrometry | Cysteine Endopeptidases - metabolism | Protozoan Proteins - metabolism | Tyrosine Transaminase - analysis | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Tyrosine Transaminase - metabolism | Glutamate Dehydrogenase - metabolism | Drug Resistance | Superoxide Dismutase - metabolism | Peptide Hydrolases - metabolism | Cyclophilin A - metabolism | Nitroimidazoles - pharmacology | Superoxide Dismutase - analysis | Trypanosoma cruzi - metabolism | Peptide Hydrolases - analysis | Proteome - analysis | Animals | Cyclophilin A - analysis | Peroxiredoxins - analysis | Trypanocidal Agents - pharmacology | Trypanosoma cruzi - drug effects | Hydroxyprostaglandin Dehydrogenases - analysis | Protozoan Proteins - analysis | Proteome - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article