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Critical care medicine, ISSN 0090-3493, 6/2018, Volume 46, Issue 6, pp. e600 - e608
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 12/2015, Volume 19, Issue Pt A, pp. 278 - 287
•4′-Demethylnobiletin (4DN) dose-dependently inhibited lipopolysaccharide (LPS)-induced nitric oxide production in macrophages.•4DN inhibited reduced... 
NF-κB | Metabolites | 4′-Demethylnobiletin | Nobiletin | Nrf2 | Anti-inflammation | 4'-Demethylnobiletin | ACTIVATION | CITRUS NOBILETIN | FOOD SCIENCE & TECHNOLOGY | MOUSE | SUPPRESSION | HUMAN MONOCYTES | COLON-CANCER CELLS | NF-kappa B | INFLAMMATION | MICE | NF-KAPPA-B | 4 '-Demethylnobiletin | nobiletin | COX-2 | 4′-demethylnobiletin | iNOS | anti-inflammation | AP-1 | metabolites
Journal Article
by Wei, D and Zhang, G and Zhu, Z and Zheng, Y and Yan, F and Pan, CX and Wang, ZY and Li, X and Wang, FL and Meng, P and Zheng, WX and Yan, Z and Zhai, DS and Lu, ZF and Yuan, JL
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 07/2019, Volume 10, p. 690
Nobiletin is a polymethoxy flavonoid isolated from Citrus depressa and Citrus reticulata. It has been reported that nobiletin can suppress tumors. We primarily... 
MIGRATION | nobiletin | METAANALYSIS | SRC | CITRUS NOBILETIN | STAT3 | AKT | PROLIFERATION | renal carcinoma cells | YY1AP1 | INVASION | PHARMACOLOGY & PHARMACY | CANCER STATISTICS | SUPPRESSES | TUMOR-GROWTH | Flow cytometry | Flavonoids | Usage | Flavones | Bioflavonoids | Analysis | Cancer cells | Cellular signal transduction | Research | Carcinoma | Cancer
Journal Article
by Wang, YB and Xie, J and Ai, ZX and Su, JS
INTERNATIONAL JOURNAL OF NANOMEDICINE, ISSN 1178-2013, 2019, Volume 14, pp. 7839 - 7849
Journal Article
International Journal of Oncology, ISSN 1019-6439, 06/2015, Volume 46, Issue 6, pp. 2629 - 2638
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 05/2017, Volume 18, Issue 5, p. 935
Journal Article
Cell Metabolism, ISSN 1550-4131, 04/2016, Volume 23, Issue 4, pp. 610 - 621
Journal Article
Frontiers in pharmacology, ISSN 1663-9812, 2019, Volume 10, p. 570
Osteoarthritis (OA), a common degenerative joint disease, is principally characterized by inflammation and destruction of cartilage. Nobiletin, an extract of... 
NF-κB | nobiletin | chondrocyte | inflammation | osteoarthritis | interleukin-1β
Journal Article
Food Chemistry, ISSN 0308-8146, 03/2017, Volume 218, pp. 15 - 21
•Alkaline hot water increased the yield of orange peel extract.•Orange peel extract have higher anti-inflammatory activity than their equivalent flavonoid... 
Nchenpi | Antioxidant | Nobiletin | Orange peel extract | Flavonoid | Anti-inflammation | CAPACITY | CELLS | PERICARPIUM | PHENOLIC-COMPOUNDS | FOOD SCIENCE & TECHNOLOGY | CACO-2 | HEAT-TREATMENT | NUTRITION & DIETETICS | NITRIC-OXIDE | "Nchenpi" | CHEMISTRY, APPLIED | EXTRACTS | CITRI-RETICULATAE | Flavones - analysis | Flavonoids - analysis | Citrus - chemistry | Drugs, Chinese Herbal - pharmacology | Chromatography, High Pressure Liquid | Nitric Oxide - analysis | Plant Extracts - analysis | Anti-Inflammatory Agents - analysis | Nitric Oxide Synthase Type II - antagonists & inhibitors | China | Flavonoids - pharmacology | Amidines - analysis | Antioxidants - analysis | Flavones - pharmacology | Picrates - analysis | Phenols - pharmacology | Cell Survival - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Fruit - chemistry | Nitric Oxide - antagonists & inhibitors | Sulfonic Acids - analysis | Antioxidants - pharmacology | California | Biphenyl Compounds - analysis | Phenols - analysis | Animals | Benzothiazoles - analysis | Cyclooxygenase 2 - metabolism | Cyclooxygenase 2 Inhibitors - analysis | RAW 264.7 Cells | Mice | Nitric Oxide Synthase Type II - metabolism | Antioxidants | Flavonoids | Flavones | Anti-inflammatory drugs | Bioflavonoids | Citrus | Citrus fruits | COX-2 inhibitors | Crop yields | Nitric oxide | Gastrointestinal diseases | Biological response modifiers | Mitogens | Interferon gamma | Isoflavones | Index Medicus
Journal Article
by Kim, JJ and Kim, K and Jung, YR and Bian, Y and Ngo, T and Bae, ON and Lim, KM and Chung, JH
MOLECULES, ISSN 1420-3049, 03/2019, Volume 24, Issue 7, p. 1197
A single herb can contain multiple constituents with diverse bioactivities. We found that the extract of Citrus unshiu peel (CUP), induced abnormal... 
nobiletin | MECHANISM | Citrus unshiu | BIOCHEMISTRY & MOLECULAR BIOLOGY | synephrine | bioassay | PLANTS | vasoconstriction | OBESE | hypertension | CHEMISTRY, MULTIDISCIPLINARY
Journal Article